GO:0042730

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Name fibrinolysis
Categary Process
Go Slim No
Go Link GO:0042730
Unique Molecular Interactions 361
Total Molecular Interactions 539
Total Single Events 3273
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fibrinolysis. They are ordered first by their pain relevance and then by number of times they were reported for fibrinolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
2 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
3 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
4 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
5 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
6 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
7 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
8 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
9 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
10 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
11 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 0.02 1.29 0.9
12 INT153516 PLG Positive_regulation of Pas5a 1 0.57 0.05 0.83
13 INT125523 PLAT Positive_regulation of GDF15 1 0.13 1.33 0.75
14 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72
15 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
16 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
17 INT180961 Binding of MOCS1 and PLAU 1 0.00 0.61 0.67
18 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
19 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64
20 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63
21 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
22 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
23 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
24 INT101719 PLAT Positive_regulation of NFYC 1 0.13 0.1 0.6
25 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59
26 INT207504 Binding of ap and Klkb1 1 0.13 0 0.58
27 INT37034 PLAT Positive_regulation of PLDN 1 0.08 0.15 0.58
28 INT37035 PLAT Negative_regulation of ODC1 1 0.45 0.15 0.58
29 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
30 INT96089 Binding of F2 and Pf4 1 0.00 1.31 0.56
31 INT96098 Binding of PPBP and F2 1 0.00 1.31 0.56
32 INT113548 NFKB1 Regulation of Localization of PLAU 1 0.26 1.93 0.55
33 INT99736 Binding of PLG and Serpinf2 1 0.01 0.73 0.55
34 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52
35 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5
36 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
37 INT84520 Gene_expression of F2 Positive_regulation of F13A1 1 0.03 0.16 0.49
38 INT180958 Binding of F13A1 and PLAT 2 0.03 2.16 0.47
39 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46
40 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46
41 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45
42 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
43 INT353631 Oas1a Positive_regulation of Klkb1 1 0.00 0 0.44
44 INT48715 PTGER2 Regulation of Gene_expression of SERPINE1 1 0.21 0.6 0.44
45 INT48716 IL1B Regulation of Gene_expression of SERPINE1 1 0.42 0.59 0.44
46 INT125520 PLAT Positive_regulation of Gene_expression of GDF15 1 0.13 0.74 0.42
47 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
48 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
49 INT120894 Binding of Gp1ba and Vwf 1 0.00 1.38 0.4
50 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
51 INT48714 PTGER2 Negative_regulation of Gene_expression of SERPINE1 1 0.15 0.28 0.38
52 INT113560 Negative_regulation of Binding of FN1 and PLAUR 1 0.26 0.87 0.37
53 INT113556 Binding of FN1 and PLAUR 1 0.22 0.81 0.37
54 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
55 INT161004 Binding of Cpe and Cpb2 1 0.03 0.53 0.37
56 INT161006 Itgam Regulation of Cpb2 1 0.07 0.52 0.37
57 INT161003 Binding of Itgam and Cpb2 1 0.10 0.52 0.37
58 INT113553 Negative_regulation of Binding of PLAU and PLAUR 1 0.36 0.87 0.37
59 INT161007 Gfap Regulation of Cpb2 1 0.04 0.52 0.37
60 INT160999 Binding of Gfap and Cpb2 1 0.14 0.52 0.37
61 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
62 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
63 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
64 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
65 INT214854 SERPINE1 Positive_regulation of PLAT 1 0.24 0.42 0.33
66 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
67 INT56090 TNF Regulation of SERPINE1 1 0.43 0.41 0.33
68 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33
69 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32
70 INT138469 Cpb2 Negative_regulation of Gene_expression of Ryr2 1 0.04 0.25 0.32
71 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32
72 INT338051 Ngf Positive_regulation of Localization of F2 1 0.11 0 0.32
73 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32
74 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
75 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31
76 INT207502 Positive_regulation of Binding of ap and Klkb1 1 0.18 0 0.31
77 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
78 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31
79 INT207503 Binding of Klkb1 and Scn7a 1 0.02 0 0.3
80 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
81 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
82 INT56092 FGFR1 Positive_regulation of Transcription of SERPINE1 1 0.29 0.41 0.29
83 INT96100 Binding of SELP and F2 1 0.01 0.67 0.29
84 INT247083 Binding of F5 and PLAT 1 0.03 0.88 0.29
85 INT96094 Binding of Selp and F2 1 0.00 0.67 0.29
86 INT113558 Negative_regulation of NFKB1 Negative_regulation of Localization of PLAU 1 0.41 0.97 0.29
87 INT96099 Binding of TAT and F2 1 0.01 0.68 0.29
88 INT96093 Binding of Serpinc1 and F2 1 0.00 0.68 0.29
89 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
90 INT162044 F2 Positive_regulation of Localization of FOS 1 0.32 0.9 0.28
91 INT56091 FGF2 Positive_regulation of Transcription of SERPINE1 1 0.43 0.41 0.28
92 INT162040 F2 Positive_regulation of Localization of JUN 1 0.20 0.9 0.28
93 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28
94 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
95 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27
96 INT44759 Negative_regulation of PLAT Positive_regulation of ODC1 1 0.27 0 0.27
97 INT231025 Cpb2 Positive_regulation of Gene_expression of Fos 1 0.20 0.19 0.27
98 INT231030 Cpb2 Regulation of Gene_expression of Fos 1 0.11 0.31 0.27
99 INT338039 F2 Positive_regulation of Positive_regulation of Prkca 1 0.04 0.52 0.27
100 INT44760 PLAT Positive_regulation of ODC1 1 0.29 0 0.27
101 INT207505 Negative_regulation of Binding of ap and Klkb1 1 0.15 0 0.26
102 INT125522 PLAT Regulation of Gene_expression of GDF15 1 0.08 0.46 0.26
103 INT125513 PLAT Positive_regulation of Transcription of GDF15 1 0.12 0.44 0.26
104 INT76081 Plg Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.26
105 INT76082 Plg Regulation of Gene_expression of IL6 1 0.01 0.19 0.26
106 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25
107 INT125517 Negative_regulation of PLAT Positive_regulation of GDF15 1 0.12 0.46 0.25
108 INT180964 PLG Positive_regulation of MMP13 1 0.24 0.45 0.25
109 INT31097 Binding of Penk and Plg 1 0.29 0.07 0.24
110 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
111 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
112 INT125519 Regulation of PLAT Positive_regulation of NFKB1 1 0.07 0.44 0.24
113 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
114 INT119717 Binding of ADRA1D and F12 1 0.35 0.23 0.23
115 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
116 INT37033 PLAT Negative_regulation of PLDN 1 0.08 0.07 0.23
117 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
118 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
119 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23
120 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
121 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
122 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22
123 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22
124 INT48713 PTGER1 Negative_regulation of Gene_expression of SERPINE1 1 0.02 0.28 0.22
125 INT202183 PLAU Regulation of Protein_catabolism of PLAUR 1 0.11 1.25 0.21
126 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
127 INT202184 SERPINE1 Regulation of Protein_catabolism of PLAUR 1 0.23 1.25 0.21
128 INT115006 Binding of Serpine1 and Cpb2 1 0.09 1.53 0.2
129 INT255259 Binding of Plg and Tsp1 1 0.05 0.84 0.2
130 INT27675 Plg Positive_regulation of Protein_catabolism of F13A1 1 0.00 0.75 0.2
131 INT338043 F2 Positive_regulation of Localization of Prkca 1 0.04 0.1 0.2
132 INT99735 Binding of PLG and Ppp1r1a 1 0.00 0.24 0.19
133 INT338391 Thim Positive_regulation of Cpb2 1 0.08 0.37 0.19
134 INT99727 Binding of SERPINE1 and PLG 1 0.02 0.24 0.19
135 INT99734 Binding of SERPINE1 and Serpinf2 1 0.00 0.25 0.19
136 INT46306 Asrgl1 Positive_regulation of Negative_regulation of Plg 1 0.01 1.07 0.19
137 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
138 INT338050 Ngf Positive_regulation of F2 1 0.11 0.25 0.18
139 INT253776 Binding of THBD and F2 1 0.00 1.15 0.18
140 INT247082 Binding of PLAT and PTBP1 1 0.14 0.59 0.18
141 INT338061 Nrtn Positive_regulation of F2 1 0.07 0.25 0.18
142 INT169117 PLAU Regulation of Gene_expression of MMP9 1 0.47 0.49 0.17
143 INT169118 PLAU Regulation of Gene_expression of CSF2 1 0.41 0.49 0.17
144 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 0.02 0.31 0.17
145 INT92269 Binding of F13A1 and F2 1 0.00 0.44 0.17
146 INT83514 SERPINC1 Negative_regulation of F2 2 0.16 0.62 0.16
147 INT63511 F2 Negative_regulation of SERPINE2 1 0.15 0.97 0.16
148 INT83512 F2 Negative_regulation of PLAU 1 0.27 0.57 0.16
149 INT109887 F2 Negative_regulation of F8 1 0.00 1.32 0.16
150 INT83513 Negative_regulation of SERPINC1 Negative_regulation of F2 1 0.16 0.64 0.16
151 INT83515 F2 Positive_regulation of PLAU 1 0.31 0.57 0.16
152 INT83511 F2 Negative_regulation of PRH1 1 0.01 0.6 0.15
153 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15
154 INT37659 IGHG3 Negative_regulation of F2 1 0.06 0.79 0.15
155 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15
156 INT248147 PLAT Positive_regulation of Gene_expression of CPOX 1 0.00 0.51 0.15
157 INT106008 Binding of PLAUR and Plaur 1 0.15 1.36 0.15
158 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15
159 INT319119 SERPINE1 Negative_regulation of Positive_regulation of PLG 1 0.11 1.56 0.15
160 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14
161 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
162 INT11641 Binding of SERPINE1 and Serpinc1 1 0.00 0.78 0.13
163 INT174917 Negative_regulation of PLG Negative_regulation of Positive_regulation of FUT1 1 0.01 0.68 0.13
164 INT338055 F2 Positive_regulation of Par2 1 0.08 0.22 0.13
165 INT11632 Binding of SERPINE1 and TAT 1 0.11 0.78 0.13
166 INT107005 F2 Positive_regulation of PRSS1 1 0.00 0.28 0.13
167 INT207109 F2 Positive_regulation of Phosphorylation of Akt2 1 0.08 0.25 0.12
168 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12
169 INT99737 Serpinf2 Negative_regulation of Localization of SERPINE1 1 0.00 0.24 0.12
170 INT99732 Serpinf2 Negative_regulation of PLG 1 0.01 0.24 0.12
171 INT307075 Tbxas1 Negative_regulation of Negative_regulation of PLG 1 0.01 1.22 0.11
172 INT195710 SERPINC1 Positive_regulation of F2 1 0.08 0.69 0.11
173 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
174 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 0.08 0.7 0.11
175 INT347515 Binding of GP1BA and Vwf 1 0.01 0.19 0.11
176 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11
177 INT294456 KLK4 Negative_regulation of SERPINB2 1 0.01 0 0.1
178 INT22670 PLAT Positive_regulation of SERPINE1 1 0.03 0.1 0.1
179 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1
180 INT3562 Trh Positive_regulation of Klkb1 1 0.10 0 0.1
181 INT294450 KLK4 Negative_regulation of SERPINE1 1 0.01 0 0.1
182 INT8673 Binding of F2 and F8 1 0.08 0.48 0.1
183 INT22672 Positive_regulation of Binding of SERPINE1 and PLAT 1 0.03 0.1 0.1
184 INT8672 Positive_regulation of Binding of F2 and F8 1 0.11 0.48 0.1
185 INT44591 PLAT Negative_regulation of CNOT4 1 0.10 0.33 0.1
186 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
187 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
188 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 0.02 0.17 0.09
189 INT115717 TNF Regulation of Gene_expression of PLAU 1 0.49 0.56 0.09
190 INT298502 F10 Positive_regulation of F2 1 0.00 0.12 0.09
191 INT232010 PLG Positive_regulation of TRGC1 1 0.08 0.51 0.09
192 INT115720 TNF Regulation of Gene_expression of PLAUR 1 0.49 0.56 0.09
193 INT61217 Negative_regulation of PRTN3 Negative_regulation of F2 1 0.01 0.16 0.08
194 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08
195 INT289711 Binding of F2 and Spp1 1 0.08 0.21 0.08
196 INT97314 Binding of ETFA and KRT1 1 0.07 0.75 0.08
197 INT289710 F2 Regulation of Spp1 1 0.04 0 0.08
198 INT253774 THBD Regulation of F2 1 0.00 0.61 0.08
199 INT115718 TNF Regulation of PLAU 1 0.31 0.48 0.08
200 INT115719 IL1B Regulation of PLAU 1 0.49 0.48 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for fibrinolysis. They are ordered first by their pain relevance and then by number of times they were reported in fibrinolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
2 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
3 INT24684 Localization of PLAT 30 0.78 26.21 13.56
4 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
5 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31
6 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95
7 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
8 INT18334 Positive_regulation of Cpb2 24 0.69 2.98 11.22
9 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
10 INT27937 Gene_expression of Klkb1 35 0.55 1.86 10.08
11 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
12 INT13432 Positive_regulation of Klkb1 23 0.57 5.36 8.65
13 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
14 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88
15 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
16 INT10145 Gene_expression of Plg 28 0.62 12.68 7.46
17 INT50990 Regulation of Cpb2 12 0.37 2.71 7.07
18 INT717 Regulation of F2 29 0.61 17.46 6.99
19 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
20 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74
21 INT10610 Negative_regulation of Plg 22 0.40 11.81 6.74
22 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49
23 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21
24 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
25 INT22839 Gene_expression of F2 31 0.74 15.53 5.56
26 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08
27 INT51839 Positive_regulation of Localization of PLAT 5 0.49 7.09 4.92
28 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81
29 INT15474 Gene_expression of PLAUR 36 0.75 22.32 4.63
30 INT9842 Binding of F2 36 0.47 22.79 4.42
31 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
32 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
33 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
34 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12
35 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07
36 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05
37 INT78737 Positive_regulation of Gene_expression of Cpb2 5 0.38 1.77 3.84
38 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62
39 INT28802 Binding of F2 15 0.47 8.8 3.47
40 INT63506 Localization of F2 21 0.77 7.53 3.41
41 INT25344 Localization of Plg 10 0.57 5 3.27
42 INT93343 Gene_expression of Cpb2 10 0.58 4.63 3.24
43 INT16390 Regulation of Plg 13 0.48 6.72 3.2
44 INT1924 Regulation of PLAT 11 0.60 6.3 3.16
45 INT27465 Positive_regulation of F12 21 0.70 8.09 3.06
46 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02
47 INT10101 Binding of PLAT 24 0.36 12.62 2.78
48 INT73029 Negative_regulation of Klkb1 7 0.35 0 2.72
49 INT14447 Localization of F2 20 0.79 12.77 2.67
50 INT67884 Positive_regulation of PLAU 15 0.68 11.21 2.61
51 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
52 INT104041 Positive_regulation of Cpb2 7 0.59 2.88 2.39
53 INT11357 Negative_regulation of Gene_expression of PLAU 10 0.56 5.3 2.38
54 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36
55 INT4560 Protein_catabolism of PLG 18 0.96 11.64 2.32
56 INT111922 Binding of Cpb2 3 0.41 3.12 2.3
57 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2
58 INT35058 Positive_regulation of PLAUR 11 0.61 7.21 2.16
59 INT6750 Positive_regulation of Klkb1 6 0.28 2.01 2.09
60 INT17268 Localization of PLG 9 0.78 11.71 2.06
61 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06
62 INT50896 Negative_regulation of Cpb2 6 0.37 0.6 2.01
63 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98
64 INT59283 Positive_regulation of Gene_expression of Plg 6 0.25 2.36 1.97
65 INT28830 Localization of Klkb1 9 0.61 0.6 1.96
66 INT17326 Binding of Plg 14 0.43 11.72 1.94
67 INT11364 Regulation of Gene_expression of PLAU 4 0.58 3.23 1.92
68 INT48722 Negative_regulation of Gene_expression of SERPINE1 12 0.43 7.66 1.85
69 INT27936 Positive_regulation of Gene_expression of Klkb1 5 0.41 1.28 1.75
70 INT48720 Transcription of SERPINE1 11 0.68 4.76 1.67
71 INT14405 Gene_expression of SERPINF2 14 0.65 3 1.64
72 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
73 INT73330 Positive_regulation of SERPINB2 6 0.47 5.33 1.57
74 INT115721 Positive_regulation of Gene_expression of PLAU 11 0.67 7.66 1.55
75 INT22836 Regulation of F2 9 0.59 2.3 1.49
76 INT12035 Regulation of F2 21 0.45 12.66 1.47
77 INT14404 Negative_regulation of SERPINF2 11 0.47 3.15 1.47
78 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42
79 INT16388 Protein_catabolism of Plg 6 0.79 3.46 1.4
80 INT157067 Regulation of Regulation of Cpb2 2 0.22 1.29 1.39
81 INT17325 Negative_regulation of Protein_catabolism of Plg 1 0.32 0 1.37
82 INT113567 Localization of PLAU 12 0.79 7.16 1.34
83 INT17052 Binding of SERPINB2 4 0.43 4.89 1.32
84 INT39634 Regulation of Gene_expression of F2 4 0.22 1.72 1.31
85 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3
86 INT133255 Gene_expression of Anxa2 8 0.41 8.52 1.3
87 INT39443 Positive_regulation of Positive_regulation of F2 6 0.70 4.31 1.3
88 INT2355 Negative_regulation of Klkb1 6 0.26 2.5 1.3
89 INT69723 Gene_expression of SERPINB2 7 0.60 4.54 1.28
90 INT177840 Negative_regulation of PLAU 3 0.41 3.37 1.27
91 INT10133 Negative_regulation of F12 16 0.49 5.21 1.26
92 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26
93 INT130330 Positive_regulation of Gp1ba 1 0.47 0.62 1.25
94 INT138343 Positive_regulation of Localization of F2 5 0.41 5.06 1.24
95 INT18422 Regulation of Plg 6 0.45 1.71 1.22
96 INT27155 Binding of F12 8 0.36 1.61 1.21
97 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16
98 INT122481 Binding of PLAU 10 0.36 6.1 1.16
99 INT5643 Positive_regulation of SERPINF2 3 0.35 0.94 1.09
100 INT111923 Regulation of Cpb2 1 0.33 1.3 1.08
101 INT37687 Binding of PLAUR 8 0.29 3.61 1.03
102 INT4609 Gene_expression of Klkb1 5 0.47 0.81 1.03
103 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02
104 INT101841 Localization of SERPINF2 4 0.68 1.27 1.01
105 INT108040 Gene_expression of Gp1ba 3 0.72 1.77 1
106 INT171636 Negative_regulation of Gene_expression of PLAT 6 0.35 2.92 0.93
107 INT93677 Transcription of PLAU 3 0.70 2.89 0.9
108 INT97768 Positive_regulation of Gene_expression of PLG 5 0.49 2.49 0.89
109 INT207500 Binding of Klkb1 2 0.31 0 0.87
110 INT35141 Regulation of PLG 6 0.44 2.64 0.85
111 INT196322 Binding of F2 18 0.15 7.74 0.83
112 INT48717 Positive_regulation of Localization of SERPINE1 6 0.66 2.64 0.83
113 INT160993 Negative_regulation of Cpb2 2 0.18 1.68 0.83
114 INT93676 Regulation of Transcription of PLAU 1 0.44 0.07 0.82
115 INT83577 Negative_regulation of Gene_expression of Cpb2 1 0.35 0 0.81
116 INT73030 Regulation of SERPINF2 10 0.39 5.69 0.8
117 INT79181 Negative_regulation of GP1BA 2 0.06 2.23 0.8
118 INT354257 Regulation of Localization of PLAT 1 0.18 0.91 0.79
119 INT30926 Regulation of Gene_expression of Plg 11 0.45 2.14 0.78
120 INT11919 Regulation of KRT1 9 0.10 4.97 0.77
121 INT118669 Binding of Cpb2 4 0.31 0.97 0.76
122 INT17051 Regulation of SERPINB2 2 0.41 2.41 0.74
123 INT138606 Negative_regulation of Positive_regulation of F2 2 0.12 0.54 0.74
124 INT44001 Negative_regulation of Positive_regulation of F12 5 0.59 2.53 0.73
125 INT79169 Binding of PLG 10 0.47 5.88 0.72
126 INT134754 Positive_regulation of Gene_expression of PLAT 9 0.49 4.75 0.72
127 INT13702 Protein_catabolism of Plg 4 0.12 0.88 0.69
128 INT11362 Regulation of Localization of SERPINE1 3 0.39 1.55 0.69
129 INT28835 Positive_regulation of Localization of Klkb1 2 0.41 0.17 0.69
130 INT52901 Localization of PLAUR 2 0.49 1.92 0.68
131 INT90699 Regulation of F12 4 0.45 2.7 0.67
132 INT113566 Negative_regulation of Localization of PLAU 4 0.55 2.7 0.67
133 INT113565 Regulation of PLAU 6 0.58 5.8 0.66
134 INT108039 Positive_regulation of Gene_expression of Gp1ba 1 0.15 1.12 0.64
135 INT157066 Regulation of Gene_expression of Cpb2 1 0.22 0.47 0.64
136 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63
137 INT35059 Protein_catabolism of PLAUR 5 0.88 4.61 0.61
138 INT142625 Negative_regulation of Localization of SERPINF2 1 0.31 0.16 0.59
139 INT69098 Positive_regulation of Gene_expression of F2 5 0.66 3.79 0.58
140 INT70971 Negative_regulation of Positive_regulation of SERPINE1 3 0.40 2.65 0.58
141 INT59012 Negative_regulation of Positive_regulation of Cpb2 1 0.37 0 0.58
142 INT98932 Positive_regulation of Negative_regulation of F2 1 0.04 1.06 0.58
143 INT113568 Protein_catabolism of PLAU 5 0.94 4.79 0.57
144 INT106004 Positive_regulation of Gene_expression of PLAUR 9 0.67 5.96 0.56
145 INT46340 Positive_regulation of Negative_regulation of Plg 2 0.15 1.71 0.54
146 INT58591 Negative_regulation of Positive_regulation of PLG 4 0.42 2.46 0.51
147 INT9207 Negative_regulation of SERPINB2 2 0.38 2.34 0.51
148 INT99615 Gene_expression of GP1BA 12 0.75 2.98 0.5
149 INT3561 Regulation of Klkb1 3 0.29 0.28 0.5
150 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5
151 INT130331 Negative_regulation of Gp1ba 1 0.54 0.28 0.5
152 INT130327 Negative_regulation of Gene_expression of Gp1ba 1 0.54 0.28 0.5
153 INT207492 Negative_regulation of Gene_expression of Klkb1 1 0.35 0 0.49
154 INT96864 Localization of Plg 7 0.67 2.07 0.48
155 INT151903 Positive_regulation of Positive_regulation of PLG 3 0.45 1.53 0.48
156 INT70445 Binding of KRT1 10 0.35 5.38 0.47
157 INT195092 Protein_catabolism of F2 4 0.26 2.75 0.47
158 INT56094 Protein_catabolism of SERPINE1 2 0.61 1.66 0.47
159 INT11363 Regulation of Gene_expression of PLAT 1 0.27 0.87 0.46
160 INT67179 Negative_regulation of Binding of F2 3 0.41 2.23 0.45
161 INT17269 Negative_regulation of Localization of PLG 1 0.03 0.54 0.45
162 INT113641 Negative_regulation of Gene_expression of GP1BA 4 0.57 2.2 0.44
163 INT12343 Protein_catabolism of PLAT 2 0.76 0.73 0.44
164 INT158577 Negative_regulation of Gene_expression of Plg 7 0.17 3.36 0.43
165 INT258821 Negative_regulation of Localization of PLAT 4 0.57 3.32 0.43
166 INT113564 Regulation of PLAUR 3 0.48 5.15 0.41
167 INT10102 Regulation of Binding of PLAT 2 0.42 1.24 0.41
168 INT29637 Localization of KRT1 6 0.20 5.55 0.4
169 INT18335 Positive_regulation of Positive_regulation of Cpb2 1 0.28 0 0.4
170 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39
171 INT69104 Positive_regulation of Localization of F2 2 0.66 0.06 0.39
172 INT106005 Regulation of Gene_expression of PLAUR 2 0.59 2.66 0.39
173 INT39640 Negative_regulation of Gene_expression of Plg 2 0.25 1.13 0.39
174 INT48721 Negative_regulation of Localization of SERPINE1 3 0.43 2.4 0.38
175 INT10129 Gene_expression of F12 4 0.65 3.4 0.37
176 INT69103 Negative_regulation of Localization of F2 2 0.56 0.48 0.37
177 INT92242 Binding of Plg 2 0.32 1.09 0.37
178 INT161436 Transcription of F2 2 0.69 1.21 0.36
179 INT96865 Regulation of Positive_regulation of Plg 1 0.01 0.05 0.36
180 INT203309 Regulation of Anxa2 1 0.42 1.03 0.35
181 INT85646 Transcription of PLAT 2 0.67 1.2 0.34
182 INT274379 Negative_regulation of Binding of SERPINE1 1 0.03 0.91 0.33
183 INT152276 Regulation of Positive_regulation of PLG 2 0.44 1.53 0.32
184 INT207495 Regulation of Gene_expression of Klkb1 1 0.22 0 0.32
185 INT162051 Positive_regulation of Phosphorylation of F2 1 0.29 0.99 0.3
186 INT207498 Regulation of Positive_regulation of Klkb1 1 0.42 0 0.29
187 INT207499 Transcription of Klkb1 2 0.57 0.86 0.27
188 INT180969 Positive_regulation of Protein_catabolism of PLG 1 0.36 0.47 0.27
189 INT113563 Positive_regulation of Localization of PLAU 1 0.66 0.95 0.27
190 INT162802 Regulation of Gene_expression of F2 3 0.37 1.56 0.26
191 INT48719 Negative_regulation of Transcription of SERPINE1 1 0.42 0.17 0.26
192 INT2751 Regulation of Klkb1 2 0.11 0.25 0.25
193 INT180280 Positive_regulation of Phosphorylation of SERPINE1 2 0.48 0 0.24
194 INT180281 Phosphorylation of SERPINE1 2 0.78 0 0.24
195 INT200522 Negative_regulation of Negative_regulation of PLG 2 0.41 1.53 0.24
196 INT202186 Negative_regulation of Phosphorylation of SERPINE1 1 0.41 0 0.24
197 INT92264 Protein_catabolism of F2 2 0.03 0.98 0.23
198 INT153877 Positive_regulation of Binding of Plg 1 0.44 0.41 0.23
199 INT77156 Regulation of Binding of F12 1 0.13 0.25 0.23
200 INT1920 Positive_regulation of Positive_regulation of PLAT 3 0.40 2.29 0.22
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