GO:0042734

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Name presynaptic membrane
Categary Component
Go Slim No
Go Link GO:0042734
Unique Molecular Interactions 707
Total Molecular Interactions 984
Total Single Events 10142
Pain Genes Associated 62

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for presynaptic membrane. They are ordered first by their pain relevance and then by number of times they were reported for presynaptic membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
2 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
3 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
4 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
5 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
6 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
7 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
8 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
9 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
10 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
11 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
12 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
13 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
14 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
15 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
16 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
17 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
18 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
19 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
20 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
21 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
22 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
23 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
24 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
25 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27
26 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
27 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
28 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22
29 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
30 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
31 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
32 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
33 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
34 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
35 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
36 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
37 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
38 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
39 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
40 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
41 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
42 INT87805 Pnoc Negative_regulation of Gene_expression of Fosl1 1 0.33 0 1.08
43 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
44 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
45 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
46 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
47 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
48 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
49 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
50 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
51 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
52 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
53 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03
54 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02
55 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
56 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
57 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
58 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
59 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
60 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
61 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93
62 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
63 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
64 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
65 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
66 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
67 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
68 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
69 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
70 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
71 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
72 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
73 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
74 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87
75 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
76 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83
77 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
78 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
79 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
80 INT131650 Cck Positive_regulation of Fosl1 1 0.17 0 0.8
81 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
82 INT144062 Grm8 Regulation of Localization of Pag1 1 0.21 0.63 0.79
83 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
84 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
85 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
86 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
87 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
88 INT74829 Oprd1 Regulation of Slc1a2 1 0.17 0 0.76
89 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
90 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
91 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
92 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
93 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
94 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
95 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
96 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
97 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
98 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
99 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
100 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72
101 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
102 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
103 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
104 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
105 INT197234 Grik1 Positive_regulation of Localization of Gabrg1 1 0.15 0.82 0.71
106 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
107 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
108 INT195545 Rel Regulation of Gene_expression of Grm3 1 0.01 0.46 0.71
109 INT296288 Grin2a Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
110 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
111 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
112 INT282139 Grm1 Regulation of Grip2 1 0.00 0.62 0.69
113 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69
114 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
115 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
116 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
117 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
118 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
119 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
120 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64
121 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64
122 INT197238 Grik1 Regulation of Gene_expression of Gabrg1 1 0.17 0.13 0.64
123 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
124 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64
125 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
126 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63
127 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
128 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
129 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
130 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
131 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
132 INT197239 Grik1 Regulation of Localization of Gabrg1 1 0.10 0.56 0.61
133 INT201294 Negative_regulation of Grik1 Negative_regulation of Gabrg1 1 0.30 0 0.6
134 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59
135 INT296486 Binding of Pick1 and GRIP1 1 0.03 0.32 0.59
136 INT157141 Cpox Positive_regulation of Gene_expression of Camk2a 1 0.19 0.13 0.58
137 INT296475 Binding of Pick1 and Myo18a 2 0.01 1.63 0.57
138 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
139 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57
140 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
141 INT296446 Binding of Gria2 and Gria4 1 0.13 0.55 0.57
142 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
143 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
144 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
145 INT311524 Gnrhr Positive_regulation of Transcription of Grin2a 1 0.02 0.54 0.55
146 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
147 INT343597 Gys1 Regulation of Transcription of Gria2 1 0.00 0 0.55
148 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
149 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
150 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
151 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
152 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
153 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
154 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
155 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54
156 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
157 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
158 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
159 INT208122 Grin2a Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
160 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
161 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
162 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
163 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
164 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
165 INT208120 Binding of Grin2a and Hpcal1 1 0.10 0.07 0.48
166 INT71318 Grik4 Positive_regulation of Localization of Npy 1 0.05 0 0.47
167 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
168 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
169 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
170 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
171 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
172 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
173 INT83111 LIAS Negative_regulation of Binding of Chrna7 1 0.02 0 0.45
174 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
175 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
176 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
177 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
178 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
179 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42
180 INT215651 Binding of Adora1 and Cpa1 1 0.00 0 0.42
181 INT354704 Binding of MAP3K1 and Pick1 1 0.00 0.76 0.41
182 INT160971 Gm2111 Positive_regulation of Grm7 1 0.01 0.16 0.41
183 INT141242 Binding of SYP and DNLZ 1 0.29 1.74 0.41
184 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
185 INT354719 Binding of ASIC1 and Pick1 1 0.40 2.34 0.4
186 INT106114 Binding of ASIC2 and Pick1 1 0.14 0.1 0.4
187 INT158104 Binding of Trpv1 and P2rx2 1 0.03 0.27 0.4
188 INT106116 Binding of ASIC1 and Pick1 1 0.04 0.1 0.4
189 INT223474 Binding of Grik1 and P2rx3 1 0.03 0.36 0.4
190 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
191 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
192 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
193 INT223870 Regulation of Gria2 Positive_regulation of Gene_expression of Ltp 1 0.01 0 0.4
194 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
195 INT334665 Ltp Regulation of Gria2 1 0.23 0.22 0.4
196 INT148514 Binding of Gad2 and Penk 1 0.25 0 0.4
197 INT296301 Binding of Grin2a and Kcnip3 1 0.27 0 0.4
198 INT106115 Pick1 Positive_regulation of Phosphorylation of ASIC2 1 0.13 0.07 0.39
199 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
200 INT106117 Pick1 Positive_regulation of ASIC2 1 0.14 0.09 0.39

Single Events

The table below shows the top 100 pain related interactions that have been reported for presynaptic membrane. They are ordered first by their pain relevance and then by number of times they were reported in presynaptic membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
2 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
3 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
4 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
5 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
6 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
7 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
8 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
9 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
10 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
11 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
12 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
13 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
14 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
15 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
16 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
17 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
18 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
19 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
20 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
21 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
22 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
23 INT276 Regulation of Ache 83 0.62 16.75 25.99
24 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
25 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
26 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
27 INT48536 Positive_regulation of Grm8 46 0.61 14.31 23.56
28 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
29 INT82461 Gene_expression of Gad2 40 0.78 19.12 22.79
30 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
31 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
32 INT124670 Gene_expression of Grik1 53 0.77 4.83 19.13
33 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
34 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
35 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
36 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
37 INT48055 Gene_expression of Grm1 27 0.78 14.29 17.01
38 INT62564 Gene_expression of Syp 40 0.76 15.56 17
39 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
40 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
41 INT19071 Localization of Ache 66 0.81 5.1 16.27
42 INT197210 Positive_regulation of Grik1 24 0.69 3.15 16.24
43 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
44 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
45 INT91285 Negative_regulation of P2rx2 29 0.57 12.74 15.48
46 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38
47 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
48 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
49 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
50 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
51 INT74745 Gene_expression of Grm8 30 0.68 9.85 14.52
52 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
53 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
54 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
55 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
56 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75
57 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
58 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
59 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
60 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
61 INT100919 Positive_regulation of Grm1 21 0.70 7.82 11.55
62 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
63 INT86544 Positive_regulation of Camk2a 20 0.47 4.59 11.37
64 INT7903 Positive_regulation of Fosl1 21 0.70 3.53 11.36
65 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
66 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
67 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
68 INT102370 Positive_regulation of Grm2 10 0.45 5.03 10.9
69 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
70 INT19155 Binding of Adora1 25 0.47 6.41 10.72
71 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
72 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
73 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
74 INT106477 Positive_regulation of Syp 21 0.68 8.69 10.3
75 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3
76 INT1252 Binding of Ache 46 0.48 9.94 10.25
77 INT145875 Gene_expression of Grm2 28 0.58 6.81 10.19
78 INT115614 Binding of Gria2 25 0.43 8.97 9.91
79 INT82769 Positive_regulation of Grm1 20 0.00 7.78 9.82
80 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
81 INT130280 Positive_regulation of Gene_expression of Gad2 7 0.69 8.13 9.55
82 INT105304 Negative_regulation of Gene_expression of P2rx2 11 0.28 11.07 9.53
83 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
84 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47
85 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
86 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
87 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
88 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
89 INT34544 Gene_expression of L1cam 43 0.77 5.3 8.89
90 INT63739 Regulation of Gad2 15 0.58 3.44 8.86
91 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71
92 INT48088 Regulation of Grm8 12 0.62 4.93 8.71
93 INT71590 Gene_expression of Camk2a 17 0.78 2.3 8.63
94 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
95 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
96 INT69460 Positive_regulation of Grm2 12 0.49 6.54 8.18
97 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
98 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
99 INT73544 Gene_expression of Grm7 34 0.64 31.28 8.04
100 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
101 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
102 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
103 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53
104 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
105 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
106 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
107 INT9167 Binding of Adora1 6 0.40 0.53 6.9
108 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
109 INT197216 Localization of Grik1 9 0.80 0.39 6.78
110 INT120261 Binding of P2rx2 19 0.28 5.8 6.72
111 INT94649 Gene_expression of Grm1 19 0.77 5.11 6.58
112 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
113 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
114 INT115677 Positive_regulation of Gene_expression of Syp 15 0.63 4.69 6.25
115 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
116 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14
117 INT141751 Localization of Syt1 21 0.78 11.19 5.98
118 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
119 INT157121 Gene_expression of GAD2 15 0.67 7.21 5.91
120 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
121 INT111384 Gene_expression of Adora3 18 0.75 10.53 5.73
122 INT75978 Transcription of Gad2 11 0.69 2.28 5.68
123 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
124 INT80344 Regulation of Camk2a 9 0.56 0.99 5.66
125 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55
126 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
127 INT113153 Regulation of Grm1 6 0.44 4.11 5.41
128 INT188852 Gene_expression of Pde2a 13 0.19 6.44 5.35
129 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
130 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31
131 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
132 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
133 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
134 INT141750 Positive_regulation of Localization of Syt1 10 0.67 5.53 5.28
135 INT74394 Negative_regulation of Gad2 6 0.42 1.96 5.26
136 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25
137 INT208108 Localization of Grin2a 19 0.70 1.5 5.22
138 INT105306 Regulation of Gene_expression of P2rx2 7 0.21 6.92 5.22
139 INT135998 Localization of Gria2 18 0.72 3.14 5.15
140 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
141 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
142 INT19549 Binding of Grin2a 12 0.45 1.24 5.09
143 INT85946 Localization of Gria2 10 0.61 1.23 5.09
144 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
145 INT5201 Negative_regulation of Gene_expression of Fosl1 8 0.54 1.63 5.06
146 INT53007 Regulation of Gene_expression of Fosl1 6 0.27 1.28 5.06
147 INT26042 Binding of Gria2 20 0.40 4.88 5.04
148 INT135474 Negative_regulation of Gene_expression of Grin2a 7 0.39 6.94 4.89
149 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
150 INT100920 Positive_regulation of Gene_expression of Grm1 7 0.70 5.88 4.87
151 INT91055 Negative_regulation of Grm1 7 0.45 5.14 4.87
152 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
153 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84
154 INT148649 Transcription of P2rx2 8 0.43 8.11 4.79
155 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
156 INT124920 Positive_regulation of Negative_regulation of Slc1a2 4 0.58 0.06 4.69
157 INT49060 Negative_regulation of Camk2a 10 0.45 2.59 4.67
158 INT197219 Positive_regulation of Gene_expression of Grik1 5 0.69 0.83 4.67
159 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
160 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
161 INT151350 Regulation of Gene_expression of Camk2a 1 0.62 0.79 4.57
162 INT79682 Gene_expression of Grm7 6 0.75 4.74 4.5
163 INT100520 Regulation of Grm1 8 0.44 1.3 4.48
164 INT145876 Regulation of Gene_expression of Grm2 3 0.00 2.4 4.46
165 INT197230 Regulation of Positive_regulation of Grik1 4 0.45 0 4.42
166 INT111055 Localization of Slc1a2 4 0.71 2.04 4.41
167 INT71594 Positive_regulation of Gene_expression of Camk2a 8 0.47 1.07 4.35
168 INT63740 Positive_regulation of Gad2 11 0.66 0.78 4.32
169 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
170 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
171 INT11946 Transcription of Ache 18 0.69 2.62 4.13
172 INT195522 Gene_expression of Grm3 12 0.24 2.32 4.13
173 INT106274 Positive_regulation of Syt1 16 0.67 9.76 4.1
174 INT74814 Binding of Grm1 5 0.45 2.69 4.1
175 INT63481 Gene_expression of FOSL1 11 0.75 1.39 4.01
176 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
177 INT85190 Positive_regulation of FOSL1 5 0.67 4.21 3.97
178 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
179 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92
180 INT89516 Negative_regulation of Grm8 7 0.41 4.01 3.82
181 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
182 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
183 INT121986 Phosphorylation of Grin2a 5 0.76 0.83 3.71
184 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
185 INT131969 Regulation of Grik1 6 0.61 0.57 3.69
186 INT22578 Gene_expression of Syt1 43 0.77 11.02 3.66
187 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
188 INT215163 Phosphorylation of P2rx2 19 0.60 1.43 3.62
189 INT79680 Binding of Grm7 6 0.47 2.83 3.58
190 INT8778 Regulation of Ache 17 0.62 3.7 3.57
191 INT197207 Negative_regulation of Grik1 5 0.43 1.91 3.5
192 INT215604 Localization of Adora1 10 0.78 1.47 3.49
193 INT99535 Transcription of Slc1a2 6 0.72 1.31 3.46
194 INT209221 Regulation of Gene_expression of Grin2a 5 0.24 2.81 3.45
195 INT145873 Positive_regulation of Gene_expression of Grm2 3 0.26 3.44 3.45
196 INT95785 Positive_regulation of Positive_regulation of Grm1 6 0.49 3.59 3.3
197 INT170351 Positive_regulation of Gene_expression of Gria2 13 0.67 3.67 3.27
198 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
199 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
200 INT81830 Localization of P2rx2 14 0.73 5.42 3.16
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