GO:0042743

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Name hydrogen peroxide metabolic process
Categary Process
Go Slim No
Go Link GO:0042743
Unique Molecular Interactions 46
Total Molecular Interactions 58
Total Single Events 649
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hydrogen peroxide metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for hydrogen peroxide metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
2 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
3 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
4 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
5 INT351391 Binding of Sod2 and Gtf3a 1 0.00 0.18 0.27
6 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
7 INT199191 Negative_regulation of Sod2 Positive_regulation of Ros1 1 0.08 0 0.19
8 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
9 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12
10 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11
11 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 0.11 0.41 0.11
12 INT356272 Egf Negative_regulation of Gene_expression of Egfr 1 0.15 0.2 0.1
13 INT55502 NDUFC1 Regulation of Nox1 1 0.00 0 0.08
14 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
15 INT309390 Gene_expression of Sod2 Negative_regulation of Nos3 1 0.31 0.2 0.08
16 INT201736 Nfkb1 Positive_regulation of Transcription of Sod2 1 0.01 0.93 0.08
17 INT297735 Cbr1 Positive_regulation of Sod2 1 0.11 1.28 0.07
18 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
19 INT243119 Binding of amd and Sod2 1 0.29 3.25 0.06
20 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
21 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
22 INT143993 Prdx2 Positive_regulation of Atp13a4 1 0.00 0 0.05
23 INT266902 Nfe2l2 Positive_regulation of Sod2 1 0.16 0.19 0.04
24 INT204172 Regulation of Binding of Cs and Nox1 1 0.08 1.01 0.04
25 INT252808 TNF Positive_regulation of NOX1 1 0.06 1.03 0.04
26 INT266898 Gtf3a Positive_regulation of Sod2 1 0.00 0 0.04
27 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
28 INT204173 Binding of Cs and Nox1 1 0.07 1 0.04
29 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
30 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
31 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
32 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
33 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
34 INT353283 Prdx2 Positive_regulation of Phosphorylation of Tgif1 1 0.10 0.06 0.03
35 INT353292 Prdx2 Positive_regulation of Tgif1 1 0.10 0.06 0.03
36 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
37 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
38 INT317316 Park7 Positive_regulation of Protein_catabolism of Hmbs 1 0.11 0.68 0
39 INT257344 Gene_expression of Cyba Positive_regulation of Nox1 1 0.23 1.15 0
40 INT161454 Mmp8 Positive_regulation of Egfr 1 0.36 0 0
41 INT317324 Park7 Positive_regulation of Protein_catabolism of SNCAIP 1 0.38 0.69 0
42 INT330056 Bcl2 Regulation of Localization of Cyct 1 0.27 0.97 0
43 INT317308 Binding of Park7 and Mul1 1 0.01 0.62 0
44 INT257346 Gene_expression of Lox Positive_regulation of Nox1 1 0.02 0.57 0
45 INT349296 Binding of CSF2 and PARK7 1 0.24 1.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hydrogen peroxide metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in hydrogen peroxide metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
2 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
3 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
4 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
5 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
6 INT4545 Negative_regulation of Nox1 15 0.53 10.08 3.4
7 INT172852 Localization of Cyct 28 0.78 21.42 3.34
8 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
9 INT172853 Positive_regulation of Localization of Cyct 14 0.67 10.48 2.65
10 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08
11 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
12 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
13 INT152569 Positive_regulation of Gene_expression of NOX1 1 0.31 0.67 1.51
14 INT152560 Gene_expression of NOX1 3 0.49 0.73 1.49
15 INT154763 Gene_expression of Nox1 3 0.67 1.83 1.48
16 INT154764 Localization of Nox1 1 0.65 1.07 1.47
17 INT108249 Negative_regulation of Prdx2 3 0.32 1.85 1.36
18 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
19 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
20 INT238533 Negative_regulation of Localization of Cyct 7 0.57 5.75 1.15
21 INT108243 Positive_regulation of Prdx2 3 0.34 0.85 0.95
22 INT42504 Negative_regulation of Nox1 5 0.43 0.55 0.91
23 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9
24 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
25 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
26 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
27 INT266894 Positive_regulation of Positive_regulation of Sod2 5 0.41 3.26 0.67
28 INT66783 Positive_regulation of Negative_regulation of Nox1 1 0.63 0.81 0.66
29 INT193672 Gene_expression of Prdx2 3 0.50 2.75 0.64
30 INT270033 Regulation of Gene_expression of Sod2 5 0.45 2.34 0.63
31 INT66903 Positive_regulation of Nox1 3 0.25 1.1 0.62
32 INT147440 Gene_expression of Nox1 3 0.57 1.61 0.6
33 INT111960 Binding of Sod2 4 0.37 2.03 0.59
34 INT320644 Binding of Egfr 7 0.34 5.9 0.56
35 INT79725 Regulation of Sod2 8 0.61 4.95 0.54
36 INT142943 Phosphorylation of Egfr 5 0.81 1.56 0.45
37 INT142942 Positive_regulation of Phosphorylation of Egfr 4 0.68 1.52 0.45
38 INT65962 Negative_regulation of NOX1 1 0.07 0.89 0.39
39 INT124298 Localization of Sod2 8 0.74 3.5 0.37
40 INT275368 Gene_expression of Cyct 5 0.65 3.21 0.37
41 INT275370 Positive_regulation of Gene_expression of Cyct 1 0.49 1.62 0.37
42 INT144475 Protein_catabolism of Sod2 1 0.17 0.58 0.33
43 INT349301 Negative_regulation of PARK7 1 0.41 3.44 0.26
44 INT143991 Gene_expression of Prdx2 5 0.61 1.54 0.22
45 INT353278 Binding of Prdx2 1 0.21 0.05 0.18
46 INT353270 Regulation of Binding of Prdx2 1 0.25 0.05 0.18
47 INT353274 Transcription of Prdx2 1 0.39 0.51 0.16
48 INT124301 Negative_regulation of Localization of Sod2 1 0.38 1.25 0.16
49 INT353264 Negative_regulation of Negative_regulation of Prdx2 1 0.24 0.45 0.15
50 INT144682 Negative_regulation of Regulation of Egfr 1 0.43 0.41 0.15
51 INT299514 Localization of Egfr 2 0.37 0.38 0.14
52 INT281868 Negative_regulation of Park7 1 0.00 1.69 0.14
53 INT233419 Negative_regulation of Positive_regulation of Egfr 2 0.40 0.97 0.12
54 INT270029 Negative_regulation of Phosphorylation of Sod2 1 0.26 1.3 0.12
55 INT349300 Gene_expression of PARK7 1 0.75 8.65 0.12
56 INT270035 Phosphorylation of Sod2 1 0.50 1.29 0.12
57 INT266895 Positive_regulation of Negative_regulation of Sod2 2 0.46 1.36 0.11
58 INT204986 Gene_expression of Park7 5 0.38 5.48 0.1
59 INT173981 Gene_expression of Park7 2 0.56 0.73 0.1
60 INT219647 Negative_regulation of Negative_regulation of Egfr 1 0.19 0.13 0.1
61 INT193676 Positive_regulation of Gene_expression of Prdx2 2 0.06 1.31 0.09
62 INT94000 Positive_regulation of NOX1 1 0.20 0.2 0.09
63 INT309388 Regulation of Positive_regulation of Sod2 1 0.41 0.26 0.08
64 INT71291 Binding of Nox1 1 0.11 0.25 0.08
65 INT71290 Regulation of Nox1 1 0.08 0.25 0.08
66 INT243711 Binding of Park7 3 0.25 1.5 0.06
67 INT299512 Regulation of Localization of Egfr 1 0.13 0.11 0.06
68 INT205021 Positive_regulation of Gene_expression of Egfr 3 0.64 4.15 0.05
69 INT204990 Positive_regulation of Gene_expression of Park7 2 0.24 1.79 0.05
70 INT204169 Regulation of Nox1 1 0.16 1 0.04
71 INT315158 Positive_regulation of Cyct 3 0.67 3.03 0.03
72 INT204973 Positive_regulation of Park7 2 0.23 1.62 0.03
73 INT199177 Positive_regulation of Localization of Sod2 2 0.37 0.06 0.03
74 INT297729 Regulation of Regulation of Sod2 1 0.37 0.05 0.03
75 INT204164 Negative_regulation of Positive_regulation of Nox1 1 0.17 1.02 0.03
76 INT239155 Positive_regulation of Transcription of Sod2 1 0.62 1.75 0.03
77 INT143990 Regulation of Prdx2 1 0.22 0 0.03
78 INT204970 Localization of Park7 3 0.54 2.76 0
79 INT349303 Positive_regulation of Positive_regulation of PARK7 1 0.49 1 0
80 INT295905 Negative_regulation of Cyct 1 0.41 0.94 0
81 INT330034 Binding of Cyct 1 0.35 0.95 0
82 INT204167 Positive_regulation of Nox1 1 0.19 1 0
83 INT204162 Negative_regulation of Binding of Nox1 1 0.17 0.06 0
84 INT204166 Regulation of Negative_regulation of Nox1 1 0.11 0.96 0
85 INT257320 Negative_regulation of Gene_expression of Nox1 1 0.22 0.58 0
86 INT298775 Regulation of NOX1 1 0.00 0.67 0
87 INT349298 Phosphorylation of PARK7 1 0.79 0.9 0
88 INT295912 Negative_regulation of Negative_regulation of Cyct 1 0.41 0.94 0
89 INT349304 Positive_regulation of PARK7 1 0.67 9.44 0
90 INT204163 Binding of Nox1 1 0.15 0.06 0
91 INT334699 Positive_regulation of Positive_regulation of Cyct 1 0.49 0.82 0
92 INT275369 Regulation of Localization of Cyct 1 0.44 0 0
93 INT208272 Regulation of Gene_expression of Park7 1 0.19 0.27 0
94 INT349302 Localization of PARK7 1 0.78 3.09 0
95 INT349299 Binding of PARK7 1 0.41 1.86 0
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