GO:0042752

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Name regulation of circadian rhythm
Categary Process
Go Slim No
Go Link GO:0042752
Unique Molecular Interactions 313
Total Molecular Interactions 415
Total Single Events 3750
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of circadian rhythm. They are ordered first by their pain relevance and then by number of times they were reported for regulation of circadian rhythm. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
2 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
3 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
4 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
5 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
6 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
7 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
8 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
9 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
10 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
11 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
12 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
13 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
14 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
15 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
16 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
17 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
18 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
19 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
20 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
21 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
22 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
23 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
24 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
25 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
26 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
27 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
28 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
29 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
30 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
31 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
32 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
33 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
34 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
35 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
36 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
37 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
38 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
39 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
40 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
41 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
42 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
43 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
44 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
45 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
46 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
47 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
48 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
49 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
50 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
51 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
52 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
53 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
54 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
55 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
56 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
57 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
58 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
59 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
60 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
61 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
62 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
63 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
64 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
65 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
66 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
67 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
68 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
69 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
70 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
71 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
72 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
73 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
74 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
75 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
76 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
77 INT92974 Creb1 Regulation of Positive_regulation of Galr1 1 0.32 0 0.57
78 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
79 INT305732 Tst Positive_regulation of Creb1 1 0.12 0.33 0.57
80 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
81 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
82 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
83 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
84 INT141371 Positive_regulation of CREM Negative_regulation of Crem 1 0.00 0 0.54
85 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
86 INT141372 CREM Negative_regulation of Crem 1 0.00 0 0.53
87 INT305738 Binding of Creb1 and Atf6b 1 0.08 0.34 0.53
88 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
89 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
90 INT305735 Binding of Bdnf and Creb1 1 0.08 0.49 0.47
91 INT305746 Positive_regulation of Creb1 Positive_regulation of BDNF 1 0.32 0.41 0.47
92 INT305743 Binding of Bdnf and Positive_regulation of Positive_regulation of Creb1 1 0.11 0.49 0.47
93 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47
94 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
95 INT305736 Positive_regulation of Creb1 Positive_regulation of Bdnf 1 0.10 0.41 0.46
96 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
97 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
98 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
99 INT317636 Creb1 Positive_regulation of Phosphorylation of Hmmr 1 0.04 0.55 0.45
100 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
101 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
102 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
103 INT106333 Olr1254 Positive_regulation of Creb1 1 0.02 0 0.43
104 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
105 INT186148 Camk4 Positive_regulation of Phosphorylation of Creb1 2 0.50 1.11 0.4
106 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4
107 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39
108 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38
109 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
110 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36
111 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36
112 INT274937 Ephb2 Regulation of Phosphorylation of Creb1 1 0.21 0 0.36
113 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33
114 INT207212 Creb1 Regulation of Bdnf 1 0.17 0.92 0.32
115 INT126851 Prkcg Positive_regulation of Creb1 1 0.46 0.09 0.32
116 INT182837 Binding of Creb1 and Crebbp 1 0.12 0.57 0.32
117 INT126852 Prkaca Positive_regulation of Creb1 1 0.27 0.09 0.32
118 INT124258 Creb1 Regulation of Gene_expression of Cpox 1 0.17 0.44 0.32
119 INT186430 Creb1 Positive_regulation of Trib3 1 0.04 0.17 0.3
120 INT118655 Bdnf Positive_regulation of Phosphorylation of Creb1 1 0.44 0.16 0.3
121 INT118653 Binding of Bdnf and Creb1 1 0.39 0.19 0.3
122 INT186152 Camk4 Regulation of Phosphorylation of Creb1 3 0.27 0.44 0.29
123 INT73657 Binding of Jun and Creb1 1 0.25 0.5 0.29
124 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28
125 INT296284 Calm3 Regulation of Positive_regulation of Creb1 1 0.09 0.31 0.28
126 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28
127 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28
128 INT286701 Rps6ka5 Positive_regulation of Phosphorylation of Creb1 1 0.20 0.18 0.28
129 INT283732 Prkaca Positive_regulation of Creb1 1 0.03 0 0.28
130 INT283733 Trib3 Positive_regulation of Creb1 1 0.00 0 0.28
131 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
132 INT296287 Camk4 Regulation of Positive_regulation of Creb1 1 0.27 0.31 0.27
133 INT186151 Camk4 Regulation of Creb1 2 0.27 1.06 0.25
134 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
135 INT194714 CREB1 Regulation of Gene_expression of IK 1 0.00 0.07 0.25
136 INT169049 Positive_regulation of Binding of Creb1 and Sult4a1 1 0.47 0.11 0.24
137 INT169051 Binding of Creb1 and Sult4a1 1 0.32 0.11 0.24
138 INT95741 Creb1 Regulation of Mapk8 1 0.39 0 0.23
139 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22
140 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22
141 INT255940 Elk1 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
142 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
143 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
144 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22
145 INT255947 CREB1 Regulation of Transcription of Elk1 1 0.03 0.12 0.22
146 INT255943 Elk1 Regulation of Binding of CREB1 1 0.03 0.12 0.22
147 INT255938 CREB1 Regulation of Binding of Elk1 1 0.03 0.12 0.22
148 INT87169 Creb1 Positive_regulation of Gene_expression of Nkx1-1 1 0.11 0.17 0.21
149 INT137228 MAPK1 Positive_regulation of Phosphorylation of Creb1 1 0.46 0 0.2
150 INT257233 PRKG1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0.09 0.2
151 INT257224 Pde5a Positive_regulation of Phosphorylation of Creb1 1 0.03 0.09 0.2
152 INT57383 Binding of Creb1 and Penk 1 0.05 0.67 0.2
153 INT99797 Jun Positive_regulation of Creb1 1 0.15 0.19 0.2
154 INT308669 CREB1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19
155 INT308657 Creb1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19
156 INT182929 Binding of CREB1 and KCNIP3 1 0.18 0.37 0.19
157 INT320260 Binding of Atf4 and Creb1 1 0.15 0.36 0.17
158 INT114936 Myoz1 Positive_regulation of Creb1 1 0.00 0 0.17
159 INT156970 Negative_regulation of Kcnip3 Positive_regulation of Transcription of Creb1 1 0.47 0.45 0.17
160 INT320257 Binding of Atf3 and Creb1 1 0.15 0.36 0.17
161 INT156971 Kcnip3 Negative_regulation of Creb1 1 0.48 0.46 0.17
162 INT194838 Binding of CREB1 and Nfatc1 1 0.01 0.07 0.16
163 INT194826 Binding of CREB1 and Crebbp 1 0.02 0.07 0.16
164 INT103889 Pdyn Regulation of Gene_expression of Creb1 1 0.03 0.19 0.15
165 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
166 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
167 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
168 INT117912 CREB1 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.89 0.13
169 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
170 INT182958 Binding of CA2 and CREB1 1 0.04 0.25 0.13
171 INT309130 Edc4 Regulation of Creb1 1 0.02 0.12 0.13
172 INT280819 Binding of Creb1 and gr 1 0.01 0 0.13
173 INT201749 Creb1 Positive_regulation of Ngf 1 0.03 0.33 0.13
174 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12
175 INT54544 CREB1 Regulation of PENK 1 0.59 0 0.12
176 INT54545 Binding of CREB1 and PENK 1 0.35 0 0.12
177 INT266063 PAG1 Regulation of Gene_expression of Creb1 1 0.06 0.53 0.12
178 INT194671 MAPKAPK2 Positive_regulation of CREB1 1 0.06 0.05 0.1
179 INT286046 Binding of Wwox and Creb1 1 0.14 1.67 0.1
180 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
181 INT194825 Camk4 Positive_regulation of CREB1 1 0.01 0 0.1
182 INT194721 MAPK1 Positive_regulation of CREB1 1 0.08 0.05 0.1
183 INT261892 Creb1 Regulation of Gene_expression of Ppp1r1b 1 0.31 1.46 0.09
184 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08
185 INT157271 Adipor1 Positive_regulation of PRKAA1 1 0.01 0.89 0.08
186 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
187 INT194668 CREB1 Negative_regulation of Transcription of IK 1 0.00 0.07 0.08
188 INT114932 Slc12a6 Positive_regulation of Phosphorylation of Creb1 1 0.00 0 0.08
189 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
190 INT77722 Ptger2 Positive_regulation of Phosphorylation of Creb1 1 0.13 0 0.07
191 INT254462 Binding of Ca2 and Creb1 1 0.16 0 0.07
192 INT275102 Prkcg Regulation of CREB1 1 0.01 0 0.06
193 INT303062 Rorb Regulation of Creb1 1 0.00 1.06 0.06
194 INT264835 Binding of Creb1 and Tpr 1 0.01 0.05 0.06
195 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
196 INT92567 Creb1 Positive_regulation of Binding of Prkaca 1 0.06 0 0.05
197 INT106194 Crem Regulation of TRPV1 1 0.00 0 0.05
198 INT273944 Negative_regulation of Creb1 Positive_regulation of Positive_regulation of Crem 1 0.26 0.62 0.05
199 INT253413 ATIC Positive_regulation of Gene_expression of Prkaa2 1 0.02 0 0.04
200 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of circadian rhythm. They are ordered first by their pain relevance and then by number of times they were reported in regulation of circadian rhythm. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
6 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
7 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
8 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
9 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
10 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
11 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
12 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
13 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
14 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
15 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
16 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
17 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
18 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
19 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
20 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
21 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
22 INT16713 Binding of Creb1 53 0.48 20.24 13.06
23 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
24 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
25 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
26 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
27 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
28 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
29 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
30 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
31 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
32 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
33 INT92971 Binding of Creb1 31 0.47 11.3 6.22
34 INT74208 Positive_regulation of Crem 14 0.69 2.49 5.98
35 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
36 INT61986 Localization of Creb1 16 0.69 2.12 5.66
37 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
38 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
39 INT121866 Localization of Creb1 13 0.73 1.95 4.48
40 INT74205 Gene_expression of Crem 6 0.77 5.31 3.93
41 INT74206 Positive_regulation of Gene_expression of Crem 6 0.69 3.3 3.85
42 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
43 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
44 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
45 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
46 INT158666 Regulation of Transcription of Creb1 6 0.45 2.41 2.44
47 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
48 INT159118 Protein_catabolism of Creb1 3 0.61 0.37 2.17
49 INT106718 Regulation of Positive_regulation of Creb1 9 0.45 3.7 2.16
50 INT69917 Negative_regulation of CREB1 8 0.58 2.28 1.59
51 INT128322 Gene_expression of Cry1 11 0.60 1.03 1.4
52 INT169776 Gene_expression of Opn4 52 0.77 8.75 1.38
53 INT128321 Regulation of Gene_expression of Cry1 2 0.34 0.09 1.38
54 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26
55 INT169721 Negative_regulation of Negative_regulation of Creb1 1 0.43 0.09 1.22
56 INT121867 Positive_regulation of Localization of Creb1 2 0.60 0.43 1.2
57 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1
58 INT207201 Positive_regulation of Transcription of Creb1 4 0.50 0.69 1.09
59 INT71476 Negative_regulation of Regulation of Creb1 1 0.18 0.17 1.06
60 INT142829 Transcription of CREB1 9 0.46 3.37 1.03
61 INT144326 Regulation of Gene_expression of Crem 1 0.58 0.15 1.02
62 INT71747 Positive_regulation of Prkaa2 19 0.46 8.76 0.98
63 INT119118 Transcription of Crem 1 0.58 0 0.89
64 INT115494 Negative_regulation of Positive_regulation of CREB1 2 0.05 1.25 0.83
65 INT54546 Binding of CREB1 9 0.41 3.44 0.72
66 INT114536 Regulation of Negative_regulation of Creb1 1 0.45 0 0.72
67 INT128314 Gene_expression of Cry2 2 0.46 0.18 0.68
68 INT128326 Regulation of Gene_expression of Cry2 1 0.03 0.09 0.68
69 INT271162 Positive_regulation of Regulation of Creb1 1 0.20 0.3 0.67
70 INT121868 Regulation of Localization of Creb1 1 0.23 0 0.66
71 INT169778 Positive_regulation of Opn4 8 0.68 1.63 0.63
72 INT93674 Regulation of Binding of Creb1 1 0.38 0.1 0.62
73 INT142827 Regulation of Gene_expression of CREB1 3 0.61 0.39 0.61
74 INT303595 Negative_regulation of Localization of Creb1 1 0.19 0.86 0.57
75 INT228570 Phosphorylation of Prkaa2 24 0.61 7.9 0.5
76 INT74207 Positive_regulation of Positive_regulation of Crem 1 0.46 0.26 0.47
77 INT207194 Regulation of Regulation of Creb1 2 0.45 1.09 0.46
78 INT317620 Negative_regulation of Binding of Creb1 1 0.40 0.81 0.46
79 INT116134 Positive_regulation of Positive_regulation of CREB1 2 0.28 0.59 0.45
80 INT142828 Regulation of Transcription of CREB1 1 0.24 0 0.45
81 INT64130 Localization of Crem 2 0.51 0.64 0.42
82 INT124256 Positive_regulation of Binding of Creb1 2 0.40 1.27 0.39
83 INT274924 Positive_regulation of Protein_catabolism of Creb1 1 0.30 0 0.39
84 INT129741 Regulation of Crem 1 0.00 0.34 0.34
85 INT217889 Binding of Cry1 4 0.32 0 0.33
86 INT124253 Negative_regulation of Binding of Creb1 3 0.42 0.75 0.32
87 INT71752 Negative_regulation of Prkaa2 17 0.39 2.81 0.3
88 INT71750 Regulation of Prkaa2 12 0.41 2.98 0.29
89 INT226115 Positive_regulation of PRKAA1 2 0.15 0.45 0.29
90 INT229206 Regulation of Positive_regulation of CREB1 2 0.11 0.25 0.25
91 INT187504 Gene_expression of Prkaa2 5 0.65 1.3 0.22
92 INT253395 Negative_regulation of Phosphorylation of Prkaa2 9 0.39 1.35 0.2
93 INT266053 Positive_regulation of Protein_catabolism of Creb1 1 0.50 0.96 0.17
94 INT273921 Regulation of Binding of Creb1 2 0.35 0.28 0.16
95 INT266056 Protein_catabolism of Creb1 1 0.88 0.95 0.16
96 INT253401 Positive_regulation of Positive_regulation of Prkaa2 2 0.33 1.39 0.15
97 INT94156 Negative_regulation of Crem 1 0.00 1.5 0.15
98 INT338872 Regulation of Regulation of Creb1 1 0.21 0.28 0.15
99 INT169775 Positive_regulation of Positive_regulation of Opn4 1 0.49 0.12 0.13
100 INT266058 Regulation of Localization of Creb1 1 0.39 0.38 0.11
101 INT207192 Negative_regulation of Transcription of Creb1 1 0.43 0.58 0.11
102 INT187495 Positive_regulation of Gene_expression of Prkaa2 1 0.49 0.09 0.11
103 INT217884 Transcription of Cry1 9 0.55 1.82 0.1
104 INT98920 Localization of CREB1 4 0.52 1.77 0.1
105 INT69911 Negative_regulation of Binding of CREB1 1 0.48 0 0.1
106 INT243453 Negative_regulation of Opn4 13 0.50 2.37 0.09
107 INT253404 Positive_regulation of Phosphorylation of Prkaa2 3 0.29 1.23 0.09
108 INT271380 Regulation of Cry1 2 0.25 0.59 0.09
109 INT253390 Negative_regulation of Positive_regulation of Prkaa2 4 0.28 0.76 0.08
110 INT264282 Positive_regulation of Gene_expression of Opn4 3 0.50 0.25 0.08
111 INT332857 Binding of Cry2 2 0.32 0 0.08
112 INT194802 Negative_regulation of Gene_expression of CREB1 1 0.14 0.07 0.08
113 INT332841 Negative_regulation of Binding of Cry1 1 0.29 0 0.08
114 INT332843 Negative_regulation of Binding of Cry2 1 0.33 0 0.08
115 INT248969 Transcription of Cry2 2 0.59 0.56 0.06
116 INT259746 Phosphorylation of CSNK1D 1 0.03 0.99 0.05
117 INT253387 Negative_regulation of Regulation of Prkaa2 1 0.28 0.08 0.05
118 INT217887 Regulation of Transcription of Cry1 2 0.46 0.06 0.04
119 INT290790 Phosphorylation of Cry2 1 0.46 0.29 0.04
120 INT290783 Protein_catabolism of Cry2 1 0.48 0.19 0.04
121 INT290799 Positive_regulation of Protein_catabolism of Cry2 1 0.34 0.19 0.04
122 INT217890 Positive_regulation of Transcription of Cry1 2 0.38 0.49 0
123 INT253402 Binding of Prkaa2 2 0.24 0.43 0
124 INT253408 Positive_regulation of Negative_regulation of Prkaa2 1 0.33 0.44 0
125 INT311757 Localization of Opn4 1 0.64 0 0
126 INT330234 Localization of Prkaa2 1 0.21 0 0
127 INT217882 Protein_catabolism of Cry1 1 0.75 0 0
128 INT217885 Positive_regulation of Cry1 1 0.30 0 0
129 INT300158 Negative_regulation of Transcription of Cry2 1 0.25 0.13 0
130 INT243454 Regulation of Gene_expression of Opn4 1 0.23 0.25 0
131 INT311762 Regulation of Opn4 1 0.27 0.19 0
132 INT217892 Negative_regulation of Gene_expression of Cry1 1 0.32 0 0
133 INT253394 Negative_regulation of Negative_regulation of Prkaa2 1 0.28 0.33 0
134 INT300160 Negative_regulation of Cry2 1 0.25 0.13 0
135 INT217880 Localization of Cry1 1 0.60 0 0
136 INT311759 Negative_regulation of Transcription of Opn4 1 0.37 0.15 0
137 INT243452 Negative_regulation of Gene_expression of Opn4 1 0.36 0.26 0
138 INT347091 Binding of Opn4 1 0.37 0.48 0
139 INT294005 Regulation of Negative_regulation of CSNK1D 1 0.28 0.19 0
140 INT311761 Transcription of Opn4 1 0.59 0.16 0
141 INT204014 Phosphorylation of Cry1 1 0.01 0.16 0
142 INT292831 Positive_regulation of Gene_expression of Cry1 1 0.54 0 0
143 INT294021 Negative_regulation of CSNK1D 1 0.26 0.17 0
144 INT238857 Phosphorylation of PRKAA1 1 0.01 1.73 0
145 INT217883 Positive_regulation of Localization of Cry1 1 0.38 0 0
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