GO:0042800

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Name histone methyltransferase activity (H3-K4 specific)
Categary Function
Go Slim No
Go Link GO:0042800
Unique Molecular Interactions 21
Total Molecular Interactions 23
Total Single Events 129
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone methyltransferase activity (H3-K4 specific). They are ordered first by their pain relevance and then by number of times they were reported for histone methyltransferase activity (H3-K4 specific). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT168256 Binding of MLL and TNFRSF1B 1 0.00 1.2 0.53
2 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49
3 INT330464 Setd1a Regulation of Gene_expression of RT1-CE1 1 0.00 0.47 0.35
4 INT330463 Setd1a Positive_regulation of Regulation of Adh1 1 0.00 0.09 0.23
5 INT232653 Binding of CD2 and MLL 1 0.02 0.27 0.1
6 INT215461 Binding of MLL and TNFSF13B 1 0.01 1.62 0.1
7 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
8 INT156144 MLL Positive_regulation of Epcam 1 0.00 0.47 0.06
9 INT312940 Chol1 Positive_regulation of Setd1a 1 0.00 0 0.06
10 INT156143 MLL Positive_regulation of PECAM1 1 0.00 0.47 0.06
11 INT312939 Binding of Hes3 and Setd1a 1 0.01 0.66 0
12 INT312945 ANTXR1 Regulation of Setd1a 1 0.00 0.36 0
13 INT227843 Binding of ERCC6 and MLL 1 0.00 0.34 0
14 INT254850 Setd1a Negative_regulation of Rac1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone methyltransferase activity (H3-K4 specific). They are ordered first by their pain relevance and then by number of times they were reported in histone methyltransferase activity (H3-K4 specific). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18
2 INT48192 Gene_expression of Setd1a 8 0.42 4.41 1.26
3 INT31014 Negative_regulation of Setd1a 4 0.27 1.11 0.88
4 INT139312 Negative_regulation of Gene_expression of MLL 2 0.00 1.22 0.56
5 INT168257 Binding of MLL 4 0.02 4.25 0.53
6 INT78201 Regulation of MLL 2 0.02 0.79 0.48
7 INT156944 Positive_regulation of Setd1a 2 0.30 1.31 0.41
8 INT156943 Negative_regulation of Negative_regulation of Setd1a 1 0.18 0.71 0.32
9 INT232656 Localization of MLL 2 0.05 2.33 0.29
10 INT156942 Positive_regulation of Gene_expression of Setd1a 1 0.21 0.58 0.28
11 INT227872 Positive_regulation of MLL 7 0.01 2.44 0.19
12 INT48193 Regulation of Setd1a 3 0.15 0.92 0.17
13 INT86107 Regulation of Negative_regulation of Setd1a 1 0.04 0.14 0
14 INT239565 Localization of Setd1a 1 0.01 0.85 0
15 INT341085 Positive_regulation of Positive_regulation of MLL 1 0.01 0.15 0
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