GO:0042809

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Name vitamin D receptor binding
Categary Function
Go Slim No
Go Link GO:0042809
Unique Molecular Interactions 74
Total Molecular Interactions 131
Total Single Events 554
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for vitamin D receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for vitamin D receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
2 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
3 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
4 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
5 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
6 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
7 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24
8 INT264189 HR Positive_regulation of Gene_expression of IL10 1 0.00 1.48 0.19
9 INT312550 DAK Positive_regulation of Rxra 1 0.00 1.48 0.18
10 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
11 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
12 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
13 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
14 INT251294 Binding of HR and MIR1249 1 0.00 0 0.15
15 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09
16 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
17 INT324731 Binding of Prkaca and HR 1 0.00 1.11 0.08
18 INT324732 Positive_regulation of Binding of Prkaca and HR 1 0.00 1.12 0.08
19 INT248704 Trib3 Positive_regulation of Phosphorylation of Rxrb 1 0.00 0.49 0.08
20 INT231638 HR Positive_regulation of Gene_expression of PTGER2 1 0.00 0 0.08
21 INT278684 Binding of NR1I3 and Rxra 1 0.00 0 0.07
22 INT236932 Binding of Rxra and Pprc1 1 0.00 0.45 0.07
23 INT278685 Binding of CASR and Rxra 1 0.00 0 0.07
24 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
25 INT285384 Binding of Rare1 and Rxra 1 0.01 0.08 0.05
26 INT187602 Binding of Ppara and Rxrb 1 0.00 0 0.05
27 INT307218 Binding of Rxra and D0Nrs1 1 0.00 0.1 0.05
28 INT248703 Mapk8 Positive_regulation of Phosphorylation of Rxrb 1 0.01 0.25 0.04
29 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
30 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
31 INT248700 Binding of Nr0b2 and Rxrb 1 0.01 0.29 0.03
32 INT297377 Binding of PPARA and Rxra 1 0.02 0.25 0.03
33 INT297375 Binding of VDR and Rxra 1 0.02 0.2 0.03
34 INT297374 Binding of TXNRD1 and Rxra 1 0.01 0.2 0.03
35 INT231633 HR Positive_regulation of Positive_regulation of PTGER2 1 0.00 0 0.03
36 INT231637 Gene_expression of HR Positive_regulation of Gene_expression of PTGER2 1 0.00 0.05 0.03
37 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
38 INT231632 HR Positive_regulation of Binding of PTGER2 1 0.00 0 0
39 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
40 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
41 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
42 INT291715 Binding of DR1 and Rxra 1 0.09 0 0
43 INT291716 Binding of SOD1 and Rxra 1 0.21 0 0
44 INT333697 Binding of Hr and Trp53 1 0.19 0.56 0
45 INT236719 Binding of Dr1 and Rxra 1 0.01 0 0
46 INT333682 Binding of Gc and Hr 1 0.02 0.5 0
47 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
48 INT239239 Binding of PPARA and RXRB 1 0.12 0.63 0
49 INT177286 Binding of CXADR and MED1 1 0.27 0 0
50 INT330959 Binding of RXRB and VDR 1 0.05 0.14 0
51 INT291712 Binding of Rxra and SPNS1 1 0.04 0 0
52 INT333693 Hr Negative_regulation of Gene_expression of Trp53 1 0.27 0.9 0
53 INT248705 Binding of Nr1i2 and Rxrb 1 0.01 0.18 0
54 INT333698 Gene_expression of Hr Negative_regulation of Casp3 1 0.14 0.73 0
55 INT135127 Binding of RXRB and NR1I2 1 0.29 0.57 0
56 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
57 INT291711 Rxra Positive_regulation of VDR 1 0.09 0 0
58 INT291713 Binding of TNFRSF10B and Rxra 1 0.05 0 0
59 INT333683 Hr Negative_regulation of Gene_expression of Gc 1 0.01 0.43 0
60 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
61 INT332735 Binding of Shbg and Hr 1 0.06 0.6 0
62 INT333686 Gene_expression of Hr Negative_regulation of Gene_expression of Trp53 1 0.23 1.02 0
63 INT333684 Binding of Hr and Hdac1 1 0.19 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for vitamin D receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in vitamin D receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
2 INT181186 Binding of Rxra 78 0.35 14.93 4.87
3 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
4 INT17039 Regulation of Hr 11 0.27 5.22 2.58
5 INT17037 Negative_regulation of Hr 11 0.22 11.81 2.46
6 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
7 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
8 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
9 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
10 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
11 INT187617 Binding of Rxrb 7 0.06 4.86 1.37
12 INT132577 Binding of RXRB 12 0.30 6.58 1.25
13 INT137860 Positive_regulation of Hr 2 0.14 3.9 1.16
14 INT166720 Positive_regulation of Rxrb 2 0.36 0.84 1.13
15 INT251303 Binding of HR 14 0.47 3.87 0.7
16 INT220433 Gene_expression of RXRB 3 0.14 1.83 0.63
17 INT114959 Gene_expression of RXRA 2 0.50 1.06 0.63
18 INT17038 Negative_regulation of Regulation of Hr 1 0.05 0.17 0.62
19 INT114960 Positive_regulation of Gene_expression of RXRA 1 0.32 0.24 0.61
20 INT199723 Localization of Rxra 8 0.59 1.31 0.58
21 INT248682 Gene_expression of Rxrb 8 0.60 1.41 0.58
22 INT114277 Regulation of Gene_expression of Rxra 1 0.28 0.75 0.58
23 INT265656 Positive_regulation of Gene_expression of RXRB 1 0.04 0.24 0.5
24 INT351328 Positive_regulation of Positive_regulation of Hr 1 0.09 1.23 0.4
25 INT264487 Regulation of Positive_regulation of Rxrb 1 0.21 0.36 0.4
26 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
27 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
28 INT285391 Binding of RXRA 2 0.03 0.08 0.36
29 INT199725 Negative_regulation of Gene_expression of Rxra 2 0.38 0.3 0.3
30 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
31 INT101839 Gene_expression of Hr 4 0.31 3.62 0.26
32 INT236564 Positive_regulation of Binding of Rxra 2 0.18 1.3 0.24
33 INT206946 Gene_expression of Rxra 4 0.60 2.2 0.17
34 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
35 INT332732 Positive_regulation of Negative_regulation of Hr 1 0.09 0.73 0.15
36 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
37 INT332731 Negative_regulation of Negative_regulation of Hr 1 0.08 1.02 0.12
38 INT332915 Positive_regulation of Localization of Rxra 1 0.03 0.3 0.11
39 INT210322 Gene_expression of HR 6 0.54 0.05 0.1
40 INT256913 Gene_expression of Hr 6 0.46 35.3 0.1
41 INT251302 Positive_regulation of Binding of HR 1 0.00 0 0.1
42 INT214072 Regulation of Gene_expression of RXRA 1 0.01 0.83 0.09
43 INT166719 Positive_regulation of Rxra 1 0.36 0.31 0.09
44 INT251307 Regulation of Binding of HR 1 0.00 0 0.07
45 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
46 INT264489 Transcription of Rxrb 1 0.53 0.09 0.07
47 INT101840 Binding of Hr 3 0.24 1 0.06
48 INT220435 Regulation of Gene_expression of RXRB 1 0.01 0.25 0.06
49 INT256518 Positive_regulation of Transcription of Rxra 1 0.04 0.24 0.06
50 INT234452 Phosphorylation of RXRB 1 0.29 0.66 0.06
51 INT220430 Negative_regulation of Gene_expression of RXRB 1 0.02 0.25 0.06
52 INT291692 Regulation of Binding of Rxra 4 0.32 0.57 0.05
53 INT333670 Regulation of Hr 1 0.32 1.59 0.05
54 INT248665 Phosphorylation of Rxrb 1 0.07 0.42 0.04
55 INT248680 Positive_regulation of Phosphorylation of Rxrb 1 0.05 0.24 0.04
56 INT225406 Transcription of Rxra 3 0.41 0.33 0.03
57 INT248671 Regulation of Rxrb 1 0.02 0.86 0.03
58 INT256507 Regulation of Transcription of Rxra 1 0.04 0.12 0.03
59 INT291693 Negative_regulation of Binding of Rxra 1 0.22 0.07 0.03
60 INT173697 Localization of HR 3 0.68 0.38 0
61 INT210320 Positive_regulation of HR 3 0.56 0 0
62 INT307189 Localization of Med1 3 0.53 0.32 0
63 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
64 INT210089 Positive_regulation of Hr 2 0.24 2.43 0
65 INT210319 Negative_regulation of HR 2 0.36 0.23 0
66 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
67 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
68 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
69 INT307188 Transcription of Med1 1 0.48 0.7 0
70 INT333677 Regulation of Gene_expression of Hr 1 0.24 2.14 0
71 INT248676 Positive_regulation of Gene_expression of Rxrb 1 0.05 0.18 0
72 INT333666 Regulation of Localization of Hr 1 0.24 0.81 0
73 INT231922 Negative_regulation of Positive_regulation of Rxra 1 0.06 0.33 0
74 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
75 INT333676 Positive_regulation of Gene_expression of Hr 1 0.36 10.93 0
76 INT177320 Binding of MED1 1 0.25 0 0
77 INT352848 Positive_regulation of Gene_expression of Hr 1 0.04 1.08 0
78 INT303035 Positive_regulation of Transcription of HR 1 0.49 0.05 0
79 INT225457 Binding of Med1 1 0.35 0.28 0
80 INT346487 Negative_regulation of Phosphorylation of RXRA 1 0.01 0.63 0
81 INT291694 Negative_regulation of Localization of Rxra 1 0.22 0 0
82 INT248686 Regulation of Gene_expression of Rxrb 1 0.04 0.23 0
83 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
84 INT291695 Regulation of Negative_regulation of Rxra 1 0.23 0.14 0
85 INT346494 Phosphorylation of RXRA 1 0.01 0.63 0
86 INT303034 Regulation of HR 1 0.52 1.03 0
87 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
88 INT333672 Binding of Hr 1 0.19 0.56 0
89 INT291698 Negative_regulation of Negative_regulation of Rxra 1 0.22 0 0
90 INT352847 Negative_regulation of Gene_expression of Hr 1 0.03 1.07 0
91 INT303033 Transcription of HR 1 0.67 0.05 0
92 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
93 INT333673 Localization of Hr 1 0.39 0.8 0
94 INT333665 Negative_regulation of Gene_expression of Hr 1 0.25 4.43 0
95 INT333674 Negative_regulation of Hr 1 0.22 0.92 0
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