GO:0042904

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Name 9-cis-retinoic acid biosynthetic process
Categary Process
Go Slim No
Go Link GO:0042904
Unique Molecular Interactions 27
Total Molecular Interactions 43
Total Single Events 316
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 9-cis-retinoic acid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for 9-cis-retinoic acid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
2 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
3 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
4 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
5 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
6 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
7 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
8 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
9 INT57171 Binding of RYBP and Cyp1a1 1 0.01 0 0.23
10 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
11 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
12 INT65883 Binding of CYP1A1 and PPP4C 1 0.02 0 0.15
13 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15
14 INT57170 Binding of Cyp1a1 and Cyp2b1 1 0.39 0 0.13
15 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
16 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
17 INT162506 Gtf3a Regulation of CYP1A1 1 0.00 0.09 0.09
18 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
19 INT206895 Binding of ESR1 and Aldh1a1 1 0.03 0 0
20 INT235303 Aldh1a1 Positive_regulation of Cpa1 1 0.17 0.4 0
21 INT342365 Binding of Rdh9 and OSBPL1A 1 0.40 0 0
22 INT235304 Binding of Aldh1a1 and Cpa1 1 0.12 0.86 0
23 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
24 INT342361 Binding of Irs1 and Rdh9 1 0.38 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 9-cis-retinoic acid biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in 9-cis-retinoic acid biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
2 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
3 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
4 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
5 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
6 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
7 INT17862 Localization of Cyp1a1 5 0.74 0.34 1.34
8 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25
9 INT68220 Binding of CYP1A1 8 0.48 0.8 0.99
10 INT195976 Gene_expression of Aldh1a1 26 0.75 14.23 0.6
11 INT38755 Regulation of Aldh1a1 3 0.44 2.14 0.55
12 INT115826 Transcription of Cyp1a1 4 0.52 1.15 0.53
13 INT2438 Regulation of Regulation of Cyp1a1 1 0.27 0 0.52
14 INT86006 Gene_expression of Aldh1a1 5 0.53 3.22 0.43
15 INT27414 Positive_regulation of Negative_regulation of Cyp1a1 1 0.49 0.44 0.41
16 INT115835 Negative_regulation of Positive_regulation of Cyp1a1 2 0.32 1.35 0.36
17 INT13676 Negative_regulation of Gene_expression of Cyp1a1 1 0.33 0.1 0.29
18 INT96886 Positive_regulation of Gene_expression of CYP1A1 8 0.64 3.15 0.27
19 INT99628 Positive_regulation of Gene_expression of Cyp1a1 4 0.25 1.3 0.27
20 INT115926 Negative_regulation of Positive_regulation of CYP1A1 1 0.30 0.16 0.27
21 INT52176 Positive_regulation of Binding of Cyp1a1 1 0.44 0 0.26
22 INT115834 Positive_regulation of Transcription of Cyp1a1 2 0.38 0.64 0.23
23 INT65885 Negative_regulation of CYP1A1 2 0.18 0.64 0.2
24 INT96884 Regulation of Gene_expression of CYP1A1 2 0.60 0.54 0.2
25 INT96889 Negative_regulation of Gene_expression of CYP1A1 2 0.42 0.9 0.2
26 INT344918 Regulation of Aldh1a1 1 0.43 0.69 0.2
27 INT134195 Regulation of Transcription of Cyp1a1 1 0.13 0.14 0.16
28 INT17866 Positive_regulation of Localization of Cyp1a1 1 0.49 0 0.12
29 INT349935 Transcription of CYP1A1 1 0.47 1.22 0.12
30 INT68218 Regulation of Positive_regulation of CYP1A1 3 0.45 2.35 0.1
31 INT17863 Regulation of Positive_regulation of Cyp1a1 1 0.27 0 0.09
32 INT342321 Gene_expression of Rdh9 1 0.75 1.1 0.07
33 INT274054 Localization of CYP1A1 1 0.12 0 0.07
34 INT342334 Positive_regulation of Gene_expression of Rdh9 1 0.48 1.1 0.07
35 INT81873 Positive_regulation of Aldh1a1 1 0.15 0.13 0.06
36 INT274056 Protein_catabolism of CYP1A1 1 0.15 0 0.06
37 INT68219 Positive_regulation of Binding of CYP1A1 1 0.50 0 0.05
38 INT167112 Regulation of CYP1A1 3 0.26 0.37 0
39 INT86007 Transcription of Aldh1a1 2 0.54 1.41 0
40 INT235278 Negative_regulation of Binding of Aldh1a1 1 0.41 0.69 0
41 INT294588 Positive_regulation of Positive_regulation of CYP1A1 1 0.07 0.25 0
42 INT342322 Regulation of Rdh9 1 0.26 0 0
43 INT342336 Binding of Rdh9 1 0.36 0.07 0
44 INT235263 Positive_regulation of Aldh1a1 1 0.49 0.44 0
45 INT235281 Localization of Aldh1a1 1 0.68 0.75 0
46 INT235279 Negative_regulation of Gene_expression of Aldh1a1 1 0.57 0.66 0
47 INT235264 Binding of Aldh1a1 1 0.36 0.69 0
48 INT235273 Regulation of Gene_expression of Aldh1a1 1 0.44 0.52 0
49 INT85223 Regulation of Localization of Cyp1a1 1 0.03 0.1 0
50 INT235266 Positive_regulation of Transcription of Aldh1a1 1 0.49 0.92 0
51 INT167111 Regulation of Binding of CYP1A1 1 0.43 0 0
52 INT235293 Transcription of Aldh1a1 1 0.67 0.92 0
53 INT86005 Positive_regulation of Transcription of Aldh1a1 1 0.39 0.86 0
54 INT235288 Negative_regulation of Aldh1a1 1 0.57 3.49 0
55 INT235286 Protein_catabolism of Aldh1a1 1 0.86 0.47 0
56 INT197269 Regulation of Gene_expression of Cyp1a1 1 0.16 0 0
57 INT235267 Positive_regulation of Gene_expression of Aldh1a1 1 0.67 3.95 0
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