GO:0042908

From wiki-pain
Jump to: navigation, search
Name xenobiotic transport
Categary Process
Go Slim No
Go Link GO:0042908
Unique Molecular Interactions 122
Total Molecular Interactions 150
Total Single Events 836
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for xenobiotic transport. They are ordered first by their pain relevance and then by number of times they were reported for xenobiotic transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
2 INT154439 Ufm1 Positive_regulation of Gene_expression of Abcb1a 1 0.00 0 0.85
3 INT106374 Olr833 Negative_regulation of Abcb1a 1 0.00 0 0.56
4 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
5 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54
6 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49
7 INT130311 Ccl4 Positive_regulation of Abcc1 1 0.47 0.28 0.47
8 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44
9 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38
10 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38
11 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
12 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36
13 INT106998 PAR4 Positive_regulation of NR1I2 1 0.22 0.67 0.35
14 INT146087 Abcb1b Regulation of Binding of Abcb1a 1 0.49 0.09 0.34
15 INT146088 Abcb1b Regulation of Abcb1a 1 0.49 0.09 0.34
16 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34
17 INT138721 Abcc1 Regulation of Gene_expression of Abcc4 1 0.50 0 0.31
18 INT133325 Mod2 Negative_regulation of Gene_expression of Abcb1a 1 0.01 0.18 0.31
19 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29
20 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27
21 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27
22 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27
23 INT114230 NR1I2 Positive_regulation of Positive_regulation of CYP2C9 1 0.13 0.61 0.27
24 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25
25 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25
26 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25
27 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24
28 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
29 INT107007 SPG21 Positive_regulation of NR1I2 1 0.39 0.39 0.22
30 INT106991 TPSD1 Positive_regulation of NR1I2 1 0.07 0.39 0.22
31 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21
32 INT112781 Abcc1 Regulation of Abcb1b 1 0.25 0 0.21
33 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2
34 INT55300 Slc2a1 Regulation of Gene_expression of Slc2a4 1 0.41 0.41 0.19
35 INT55295 Slc2a1 Regulation of Ins1 1 0.17 0.41 0.19
36 INT188922 Binding of Pc and Nr1i2 1 0.11 0 0.19
37 INT55299 Slc2a4 Regulation of Gene_expression of Slc2a1 1 0.41 0.41 0.19
38 INT326460 NR1I2 Regulation of Cyp4f18 1 0.01 0.72 0.18
39 INT138426 Abcb1b Regulation of Abcg2 1 0.29 0 0.17
40 INT151894 NR1I2 Positive_regulation of CYP3A4 1 0.19 0.23 0.16
41 INT278614 NR1I2 Regulation of Gene_expression of SULT2A1 1 0.11 0.11 0.15
42 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14
43 INT281194 Casr Positive_regulation of Positive_regulation of Nr1i2 1 0.27 0 0.13
44 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13
45 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
46 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13
47 INT107000 PRSS1 Positive_regulation of NR1I2 1 0.08 0.28 0.13
48 INT281193 Nr1i2 Positive_regulation of Positive_regulation of Casr 1 0.27 0 0.13
49 INT107009 PAR1 Positive_regulation of NR1I2 1 0.18 0.28 0.13
50 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
51 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12
52 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12
53 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12
54 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12
55 INT100479 Binding of Abcb1b and Camk1d 1 0.44 0 0.12
56 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11
57 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
58 INT262141 Edcs1 Positive_regulation of Nr1i2 1 0.02 0 0.1
59 INT262163 Positive_regulation of Binding of Nr1i2 and Plec 1 0.04 0.31 0.09
60 INT262142 Edcs1 Regulation of Nr1i2 1 0.01 0 0.09
61 INT262157 Binding of Nr1i2 and Plec 1 0.03 0.3 0.09
62 INT197644 NR1I2 Negative_regulation of Positive_regulation of CYP3A 1 0.02 0.47 0.08
63 INT197650 NR1I2 Negative_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08
64 INT197652 NR1I2 Positive_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08
65 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08
66 INT262176 Nr1i2 Regulation of Regulation of Casr 1 0.11 0.17 0.07
67 INT262219 Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07
68 INT159274 Tsiq1 Positive_regulation of Abcb1a 1 0.00 0.14 0.07
69 INT262161 Nr1i2 Positive_regulation of Gene_expression of Cyp27a1 1 0.29 0.24 0.07
70 INT262168 Nr1i2 Regulation of Casr 1 0.07 0.17 0.07
71 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07
72 INT262147 Nr1i2 Regulation of Gene_expression of Cyp2j8 1 0.00 0.07 0.07
73 INT262143 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp2d9 1 0.01 0.28 0.07
74 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
75 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
76 INT278601 NR1I2 Negative_regulation of Gene_expression of SULT2A1 1 0.10 0 0.06
77 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
78 INT262145 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.45 0.06
79 INT262209 Positive_regulation of Nr1i2 Positive_regulation of Transcription of Ppig 1 0.03 0 0.06
80 INT262233 Nr1i2 Negative_regulation of SOD1 1 0.03 0.23 0.05
81 INT278612 NR1I2 Regulation of SULT2A1 1 0.13 0 0.05
82 INT278603 NR1I2 Positive_regulation of Transcription of SULT2A1 1 0.12 0 0.05
83 INT262230 SOD1 Regulation of Nr1i2 1 0.02 0.3 0.05
84 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04
85 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04
86 INT262221 Nr1i2 Negative_regulation of Cyp24a1 1 0.27 0.15 0.04
87 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04
88 INT348220 Glp1r Regulation of Slc2a1 1 0.12 0.66 0.03
89 INT262162 Nr1i2 Regulation of Cyp2b9 1 0.14 0.14 0.03
90 INT262195 Nr1i2 Positive_regulation of Srebf1 1 0.08 0.18 0.03
91 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03
92 INT348226 Glp1r Regulation of Localization of Slc2a1 1 0.26 1.03 0.03
93 INT248701 Binding of Nr1i2 and Nr0b2 1 0.02 0.28 0.03
94 INT262184 Binding of Nr1i2 and Rare1 1 0.03 0.15 0.03
95 INT262169 Binding of Foxa2 and Nr1i2 1 0.17 0.33 0
96 INT262203 Nr1i2 Positive_regulation of Gene_expression of Hmgcs2 1 0.23 0.22 0
97 INT262170 Nr1i2 Positive_regulation of Gene_expression of Cyp24a1 1 0.29 0.4 0
98 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0
99 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0
100 INT262204 Nr1i2 Positive_regulation of Cyp3a11 1 0.33 0.08 0
101 INT262225 Binding of CYP3A4 and Nr1i2 1 0.13 0 0
102 INT135130 Binding of CYP3A4 and NR1I2 1 0.34 0.31 0
103 INT262215 Binding of Nr1i2 and Dnajc7 1 0.08 0.26 0
104 INT248705 Binding of Nr1i2 and Rxrb 1 0.01 0.18 0
105 INT248702 Nr1i2 Regulation of Transcription of Cyp3a62 1 0.03 0.17 0
106 INT262191 Binding of Nr1i2 and Foxo1 1 0.22 0.09 0
107 INT262223 Negative_regulation of Nr1i2 Negative_regulation of Gene_expression of CYP3A4 1 0.21 0.48 0
108 INT135127 Binding of RXRB and NR1I2 1 0.29 0.57 0
109 INT135129 NR1I2 Regulation of Transcription of CYP3A4 1 0.58 0.6 0
110 INT321530 Ubp1 Regulation of Abcb1b 1 0.43 0.06 0
111 INT262156 Nr1i2 Negative_regulation of Gene_expression of Hmgcs2 1 0.22 0.22 0
112 INT262192 Nr1i2 Regulation of Positive_regulation of Cyp3a11 1 0.32 0 0
113 INT135128 Binding of NR1I2 and NR1H4 1 0.09 0.57 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for xenobiotic transport. They are ordered first by their pain relevance and then by number of times they were reported in xenobiotic transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89
2 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81
3 INT83682 Positive_regulation of Abcb1a 22 0.68 3.3 15.6
4 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92
5 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39
6 INT80981 Regulation of Abcb1a 19 0.62 1.86 7.2
7 INT129901 Gene_expression of Nr1i2 60 0.73 22.44 6.04
8 INT54617 Positive_regulation of Gene_expression of Abcb1b 22 0.67 9.8 5.34
9 INT119909 Binding of Abcb1a 10 0.36 0.76 5.07
10 INT110202 Positive_regulation of Gene_expression of Abcb1a 13 0.67 2.08 5.01
11 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73
12 INT80983 Regulation of Abcb1b 16 0.60 1.95 4.32
13 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21
14 INT117828 Regulation of Gene_expression of Abcb1b 7 0.60 1.8 3.76
15 INT121942 Binding of Nr1i2 2 0.45 15.69 3.66
16 INT107011 Positive_regulation of NR1I2 14 0.49 8.85 3.11
17 INT119238 Positive_regulation of Positive_regulation of Abcb1a 5 0.40 1.14 3.09
18 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89
19 INT90299 Negative_regulation of Gene_expression of Abcb1a 4 0.43 0.54 2.65
20 INT40315 Gene_expression of Abcc1 10 0.76 5.66 2.53
21 INT129902 Regulation of Nr1i2 16 0.58 6.3 2.31
22 INT135396 Regulation of Gene_expression of Abcb1a 7 0.60 0.69 2.28
23 INT55291 Gene_expression of Slc2a1 20 0.68 11.46 2.16
24 INT60956 Binding of Abcb1b 8 0.47 2.49 2.09
25 INT112779 Positive_regulation of Abcc1 2 0.50 0.63 1.95
26 INT115309 Gene_expression of Slc2a1 6 0.75 2.85 1.64
27 INT262127 Negative_regulation of Gene_expression of Nr1i2 1 0.55 6.92 1.57
28 INT78352 Localization of Abcb1a 4 0.68 1.44 1.52
29 INT136981 Positive_regulation of Gene_expression of Nr1i2 2 0.65 3.63 1.34
30 INT147162 Positive_regulation of Abcb1b 13 0.57 7.29 1.15
31 INT262114 Negative_regulation of Nr1i2 1 0.55 4.72 1.12
32 INT154437 Positive_regulation of Slc2a1 4 0.26 2.67 1.08
33 INT130297 Positive_regulation of Gene_expression of Abcc1 3 0.56 1.06 0.97
34 INT158439 Transcription of Nr1i2 2 0.23 0.17 0.93
35 INT135398 Transcription of Abcb1a 2 0.55 1.53 0.89
36 INT283514 Localization of NR1I2 2 0.74 3.15 0.87
37 INT112780 Positive_regulation of Slc2a1 6 0.46 1.85 0.78
38 INT135399 Regulation of Positive_regulation of Abcb1a 1 0.49 0 0.73
39 INT136980 Negative_regulation of Positive_regulation of Nr1i2 1 0.48 0.33 0.72
40 INT135397 Positive_regulation of Regulation of Abcb1a 1 0.37 0 0.71
41 INT149654 Negative_regulation of NR1I2 2 0.41 1.19 0.59
42 INT215899 Negative_regulation of Gene_expression of Slc2a1 6 0.43 3.96 0.55
43 INT55292 Positive_regulation of Gene_expression of Slc2a1 5 0.61 2.98 0.46
44 INT206949 Regulation of Nr1i2 3 0.57 2.5 0.45
45 INT133322 Positive_regulation of Localization of Abcb1a 1 0.14 0.41 0.44
46 INT133324 Negative_regulation of Localization of Abcb1a 1 0.12 0.41 0.44
47 INT231553 Localization of Slc2a1 2 0.48 3.96 0.39
48 INT262054 Regulation of Gene_expression of Nr1i2 1 0.42 1.45 0.36
49 INT260463 Regulation of Slc2a1 2 0.27 1.58 0.33
50 INT80980 Regulation of Regulation of Abcb1a 1 0.45 0 0.32
51 INT80982 Regulation of Regulation of Abcb1b 1 0.60 0 0.32
52 INT135133 Binding of NR1I2 7 0.42 1.7 0.29
53 INT184526 Phosphorylation of Slc2a1 2 0.18 1.53 0.29
54 INT262086 Negative_regulation of Binding of Nr1i2 1 0.40 0.62 0.27
55 INT166936 Positive_regulation of Gene_expression of NR1I2 2 0.43 0.22 0.25
56 INT206952 Positive_regulation of Nr1i2 2 0.43 0.88 0.21
57 INT250673 Negative_regulation of Gene_expression of Abcb1b 2 0.42 1.66 0.19
58 INT262092 Regulation of Binding of Nr1i2 1 0.42 0 0.14
59 INT142509 Regulation of NR1I2 1 0.24 0 0.14
60 INT262094 Regulation of Positive_regulation of Nr1i2 2 0.42 0.52 0.13
61 INT134255 Localization of Abcb1b 1 0.78 0 0.13
62 INT262044 Transcription of Nr1i2 1 0.50 0.58 0.12
63 INT262046 Positive_regulation of Transcription of Nr1i2 1 0.44 0.59 0.12
64 INT295162 Transcription of Abcb1b 4 0.59 1.69 0.11
65 INT285348 Negative_regulation of Negative_regulation of Abcb1a 1 0.28 0.28 0.11
66 INT60955 Positive_regulation of Negative_regulation of Abcb1b 1 0.30 0.23 0.1
67 INT197658 Positive_regulation of Positive_regulation of NR1I2 1 0.30 0.54 0.08
68 INT348219 Regulation of Localization of Slc2a1 1 0.27 0.61 0.08
69 INT248675 Negative_regulation of Nr1i2 1 0.13 0.75 0.05
70 INT206945 Gene_expression of Nr1i2 8 0.63 2.03 0.04
71 INT253095 Regulation of Gene_expression of Slc2a1 1 0.30 0.14 0.04
72 INT321528 Positive_regulation of Transcription of Abcb1b 1 0.41 0.21 0.04
73 INT215896 Binding of Slc2a1 2 0.36 0.42 0.03
74 INT248688 Binding of Nr1i2 1 0.11 0.24 0.03
75 INT262068 Localization of Nr1i2 1 0.75 0.35 0.03
76 INT348202 Positive_regulation of Localization of Slc2a1 1 0.30 0.65 0.03
77 INT348212 Regulation of Gene_expression of Slc2a1 1 0.16 0.65 0
78 INT248662 Phosphorylation of Nr1i2 1 0.14 0.18 0
79 INT262073 Positive_regulation of Localization of Nr1i2 1 0.47 0.23 0
80 INT348208 Negative_regulation of Gene_expression of Slc2a1 1 0.26 0.32 0
81 INT250679 Regulation of Positive_regulation of Abcb1b 1 0.26 0.47 0
82 INT348201 Negative_regulation of Binding of Slc2a1 1 0.25 0.5 0
83 INT321523 Negative_regulation of Binding of Abcb1b 1 0.35 0 0
84 INT248673 Positive_regulation of Gene_expression of Nr1i2 1 0.11 0.18 0
85 INT348209 Negative_regulation of Slc2a1 1 0.25 0.49 0
86 INT248687 Regulation of Gene_expression of Nr1i2 1 0.10 0.49 0
87 INT215898 Regulation of Slc2a1 1 0.20 0.47 0
88 INT348216 Binding of Slc2a1 1 0.22 0.5 0
89 INT262126 Positive_regulation of Negative_regulation of Nr1i2 1 0.47 0.54 0
90 INT187890 Negative_regulation of Abcc1 1 0.25 0.06 0
91 INT248668 Positive_regulation of Transcription of Nr1i2 1 0.11 0.17 0
92 INT321527 Regulation of Transcription of Abcb1b 1 0.51 0.14 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox