GO:0042921

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Name glucocorticoid receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0042921
Unique Molecular Interactions 68
Total Molecular Interactions 90
Total Single Events 769
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glucocorticoid receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for glucocorticoid receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
2 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
3 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
4 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
5 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
6 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
7 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
8 INT52820 Oprd1 Regulation of NR3C1 1 0.02 0.17 0.61
9 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
10 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48
11 INT141729 NR3C1 Regulation of Positive_regulation of Cnr1 1 0.06 0.7 0.47
12 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
13 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44
14 INT227566 NR3C1 Positive_regulation of RS1 1 0.01 0 0.4
15 INT227568 NR3C1 Positive_regulation of HTR1A 1 0.00 0 0.4
16 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
17 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
18 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37
19 INT106511 Binding of Cpox and Ptges3 2 0.01 0.7 0.36
20 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
21 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
22 INT235884 Htr3a Regulation of Nr3c1 1 0.00 0.63 0.32
23 INT210803 Igh-Dex Regulation of Nr3c1 1 0.05 0 0.24
24 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24
25 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19
26 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 0.26 0 0.18
27 INT314269 Binding of PTGES and PTGES3 1 0.12 0.68 0.18
28 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
29 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16
30 INT146744 Binding of NR3C1 and PLA2G4A 1 0.26 0.25 0.15
31 INT276813 NR3C1 Regulation of Gene_expression of Hgs 1 0.03 1.09 0.13
32 INT276767 NR3C1 Regulation of Gene_expression of UTS2R 1 0.00 1.09 0.13
33 INT68493 Pomc Positive_regulation of NR3C1 1 0.02 0 0.12
34 INT128551 Binding of Cebpb and Nr3c1 1 0.06 0.15 0.11
35 INT352030 Binding of NR3C1 and IL2 1 0.15 0.5 0.11
36 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
37 INT227565 NR3C1 Positive_regulation of UFM1 1 0.00 0.07 0.08
38 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
39 INT278613 NR3C1 Regulation of Gene_expression of SULT2A1 1 0.02 0.05 0.07
40 INT345966 Binding of Arid1a and al44 1 0.00 1.56 0.05
41 INT336994 CALR Negative_regulation of ESR1 1 0.04 0 0
42 INT351732 SSD Regulation of CALR 1 0.01 2.95 0
43 INT307306 Gene_expression of COMP Positive_regulation of CALR 1 0.27 0.99 0
44 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0
45 INT307305 Gene_expression of COMP Positive_regulation of Positive_regulation of CALR 1 0.27 0.41 0
46 INT333928 Binding of CALR and ESR1 1 0.09 0.09 0
47 INT351733 CALR Positive_regulation of ROS1 1 0.03 0.3 0
48 INT142932 Binding of Arid1a and Samsn1 1 0.01 1.55 0
49 INT351730 CALR Positive_regulation of Positive_regulation of ROS1 1 0.02 0.72 0
50 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0
51 INT340917 Binding of Ptges3 and Ptplad1 1 0.14 0.17 0
52 INT333931 Binding of CALR and PDIA3 1 0.18 0.18 0
53 INT307309 Binding of CALR and EREG 1 0.00 0.83 0
54 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0
55 INT307310 Binding of CALR and COMP 1 0.28 0.82 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for glucocorticoid receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in glucocorticoid receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
2 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
3 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
4 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
5 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
6 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
7 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
8 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
9 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
10 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
11 INT52818 Localization of NR3C1 13 0.69 7.65 4.57
12 INT125282 Negative_regulation of Positive_regulation of NR3C1 3 0.57 0.54 4.31
13 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
14 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44
15 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
16 INT106513 Gene_expression of Ptges3 7 0.73 3.57 2.42
17 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
18 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32
19 INT125281 Positive_regulation of Positive_regulation of NR3C1 1 0.49 0 2.11
20 INT51316 Regulation of NR3C1 7 0.51 4.23 2.09
21 INT99039 Negative_regulation of Gene_expression of Nr3c1 2 0.37 1.96 2.08
22 INT70526 Binding of CALR 11 0.35 7.09 1.97
23 INT21941 Regulation of CALR 7 0.53 3.88 1.96
24 INT135313 Regulation of Gene_expression of Nr3c1 3 0.39 3.44 1.94
25 INT52305 Binding of Nr3c1 7 0.15 3.95 1.9
26 INT167456 Regulation of Gene_expression of Nr3c1 2 0.14 0.76 1.87
27 INT26750 Positive_regulation of Nr3c1 6 0.46 5.46 1.75
28 INT49448 Positive_regulation of Positive_regulation of Nr3c1 1 0.38 0 1.55
29 INT7578 Transcription of Nr3c1 5 0.32 0.43 1.47
30 INT139886 Gene_expression of PTGES3 11 0.72 1.5 1.27
31 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
32 INT91776 Negative_regulation of Gene_expression of Nr3c1 4 0.42 2.26 1.03
33 INT71314 Regulation of Ptges3 1 0.13 0.84 1.02
34 INT166449 Positive_regulation of Gene_expression of NR3C1 4 0.68 3.73 0.99
35 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
36 INT117581 Positive_regulation of Gene_expression of Ptges3 1 0.39 0.93 0.93
37 INT117584 Regulation of Gene_expression of Ptges3 1 0.21 0.93 0.93
38 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87
39 INT184157 Gene_expression of Ptges3 6 0.45 2.93 0.71
40 INT68486 Transcription of NR3C1 4 0.20 0.19 0.69
41 INT7576 Positive_regulation of Transcription of Nr3c1 1 0.19 0.3 0.62
42 INT162801 Localization of CALR 7 0.73 8.69 0.6
43 INT96323 Regulation of Transcription of Nr3c1 1 0.20 0 0.59
44 INT170768 Regulation of Gene_expression of NR3C1 3 0.42 2.61 0.58
45 INT83353 Negative_regulation of Binding of NR3C1 3 0.24 1.09 0.57
46 INT117583 Positive_regulation of Ptges3 1 0.36 0.59 0.57
47 INT130507 Negative_regulation of Ptges3 1 0.35 0.81 0.53
48 INT129748 Transcription of Nr3c1 1 0.58 0.53 0.48
49 INT129747 Regulation of Transcription of Nr3c1 1 0.22 0.53 0.48
50 INT290850 Regulation of Positive_regulation of Nr3c1 1 0.12 0.75 0.47
51 INT103896 Negative_regulation of Gene_expression of NR3C1 1 0.09 0.83 0.45
52 INT189927 Gene_expression of Arid1a 8 0.59 9.03 0.43
53 INT139890 Regulation of Gene_expression of PTGES3 2 0.50 0.82 0.43
54 INT52815 Regulation of Negative_regulation of Nr3c1 1 0.08 0.05 0.43
55 INT175024 Positive_regulation of Localization of NR3C1 1 0.10 0.5 0.41
56 INT38685 Regulation of Binding of NR3C1 2 0.61 0.59 0.4
57 INT168697 Binding of Nedd4 1 0.26 0.48 0.38
58 INT345950 Positive_regulation of Gene_expression of Arid1a 1 0.12 3.63 0.37
59 INT128546 Binding of Nr3c1 4 0.34 1.4 0.35
60 INT345951 Negative_regulation of Arid1a 1 0.10 6.11 0.33
61 INT195871 Positive_regulation of Gene_expression of CALR 9 0.29 3 0.27
62 INT189913 Positive_regulation of Arid1a 4 0.44 1.82 0.26
63 INT318982 Positive_regulation of Binding of CALR 1 0.09 0.32 0.24
64 INT310797 Positive_regulation of Gene_expression of PTGES3 1 0.17 0.7 0.23
65 INT310800 Positive_regulation of PTGES3 1 0.24 0.7 0.23
66 INT168693 Negative_regulation of Binding of Nedd4 1 0.31 0.29 0.21
67 INT168696 Positive_regulation of Binding of Nedd4 1 0.34 0.29 0.21
68 INT252169 Negative_regulation of Gene_expression of Ptges3 1 0.16 0.5 0.21
69 INT151659 Regulation of Positive_regulation of Nr3c1 1 0.03 0.1 0.2
70 INT79657 Positive_regulation of Transcription of NR3C1 1 0.17 0.09 0.19
71 INT345964 Regulation of Arid1a 1 0.11 0.95 0.19
72 INT79655 Positive_regulation of Phosphorylation of NR3C1 1 0.17 0.09 0.19
73 INT79662 Phosphorylation of NR3C1 1 0.30 0.09 0.19
74 INT317595 Negative_regulation of Transcription of Nr3c1 1 0.05 0.14 0.18
75 INT268931 Positive_regulation of Regulation of Nr3c1 1 0.10 0.34 0.13
76 INT280628 Regulation of Transcription of NR3C1 1 0.09 0 0.07
77 INT354146 Regulation of Gene_expression of CALR 1 0.04 0.73 0.07
78 INT341638 Binding of Arid1a 2 0.09 4.25 0.04
79 INT134850 Positive_regulation of Negative_regulation of Nr3c1 1 0.02 0 0.04
80 INT353546 Positive_regulation of Localization of CALR 1 0.05 0.49 0.03
81 INT310796 Transcription of PTGES3 1 0.27 0.05 0.03
82 INT307326 Negative_regulation of Gene_expression of CALR 3 0.25 1.78 0
83 INT245628 Regulation of Localization of Nr3c1 1 0.15 0 0
84 INT307324 Positive_regulation of Positive_regulation of CALR 1 0.25 0.36 0
85 INT189916 Regulation of Gene_expression of Arid1a 1 0.40 2.01 0
86 INT307331 Negative_regulation of Positive_regulation of CALR 1 0.29 0.36 0
87 INT310799 Negative_regulation of Gene_expression of PTGES3 1 0.17 0 0
88 INT307332 Negative_regulation of Localization of CALR 1 0.29 0.72 0
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