GO:0042993

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Name positive regulation of transcription factor import into nucleus
Categary Process
Go Slim No
Go Link GO:0042993
Unique Molecular Interactions 92
Total Molecular Interactions 158
Total Single Events 1141
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of transcription factor import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of transcription factor import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
6 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
7 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
8 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
9 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
10 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
11 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89
12 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
13 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
14 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
15 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
16 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
17 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
18 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
19 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
20 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
21 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
22 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
23 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
24 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
25 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
26 INT346450 Binding of IFNA1 and DDX58 1 0.01 0.54 0.15
27 INT290314 MAVS Positive_regulation of DDX58 1 0.06 0.63 0.13
28 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
29 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
30 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
31 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07
32 INT311916 Smad3 Negative_regulation of Gene_expression of Mmp13 1 0.12 0.27 0.06
33 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06
34 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
35 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
36 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04
37 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04
38 INT353294 Binding of Smad2 and Smad3 1 0.15 0.08 0.04
39 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
40 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
41 INT254852 Binding of Col7a1 and Smad3 1 0.01 0.57 0.03
42 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
43 INT346453 Binding of DDX58 and IFIH1 1 0.00 1.04 0.03
44 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0
45 INT254849 Negative_regulation of Rhoa Positive_regulation of Phosphorylation of Smad3 1 0.11 0.45 0
46 INT204997 Ppp1r15b Regulation of Mavs 1 0.00 0.87 0
47 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
48 INT298450 Binding of CDH1 and Efs 1 0.03 0.96 0
49 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0
50 INT269937 Binding of Smad3 and Mgst1 1 0.09 0 0
51 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0
52 INT338018 Binding of AR and Flna 1 0.11 0.33 0
53 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0
54 INT269919 Sox17 Negative_regulation of Binding of Smad3 1 0.36 0 0
55 INT269924 Smad3 Regulation of Gene_expression of Cdkn2b 1 0.23 0.26 0
56 INT312318 Binding of Cdh1 and Regulation of Transcription of Prl 1 0.30 0.39 0
57 INT269955 Positive_regulation of Binding of Smad3 and Sox17 1 0.39 0.05 0
58 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
59 INT254863 Tgfb1 Positive_regulation of Transcription of Smad3 1 0.03 0.23 0
60 INT310042 Binding of Cdh1 and Lsr1 1 0.01 0.09 0
61 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0
62 INT254857 Tgfb1 Positive_regulation of Phosphorylation of Smad3 1 0.03 0.44 0
63 INT255165 PM20D2 Regulation of FLNA 1 0.00 0.76 0
64 INT269921 Binding of Smad3 and Scn4a 1 0.12 0 0
65 INT269213 Binding of SNAI1 and Positive_regulation of Gene_expression of CDH1 1 0.37 1.03 0
66 INT269942 Sox17 Regulation of Smad3 1 0.37 0.12 0
67 INT312316 Gene_expression of Cdh1 Negative_regulation of Prl 1 0.29 0 0
68 INT218665 Olr811 Negative_regulation of Phosphorylation of Smad3 1 0.01 0.33 0
69 INT269929 Binding of Cdkn2b and Smad3 1 0.18 0.89 0
70 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
71 INT269935 Binding of Smad3 and Scn5a 1 0.13 0 0
72 INT269930 Binding of Smad3 and Sox17 1 0.40 1.16 0
73 INT337407 MIR200A Positive_regulation of CDH1 1 0.00 0.29 0
74 INT217314 IFNA1 Positive_regulation of MAVS 1 0.01 1.47 0
75 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
76 INT255163 Binding of FLNA and PM20D2 1 0.00 0 0
77 INT269946 Binding of Smad3 and Gopc 1 0.08 0 0
78 INT236529 Binding of Om and Flna 1 0.00 0.09 0
79 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
80 INT310039 Binding of Cdh1 and Slc30a4 1 0.04 0.46 0
81 INT298438 Binding of CDH1 and SNAI1 1 0.14 1.16 0
82 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
83 INT232594 CDH1 Regulation of HEPACAM 1 0.01 1.02 0
84 INT312317 Cdh1 Regulation of Transcription of Prl 1 0.41 0.39 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of transcription factor import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of transcription factor import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221172 Binding of Flna 32 0.42 1.37 51.59
2 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
3 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
4 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
5 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77
6 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
7 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
8 INT39948 Binding of FLNA 45 0.42 58.05 4.27
9 INT221168 Localization of Flna 1 0.58 0.05 4.05
10 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
11 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
12 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
13 INT46646 Localization of FLNA 19 0.73 18.83 2.53
14 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
15 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
16 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
17 INT221179 Regulation of Flna 1 0.24 0.13 2.04
18 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72
19 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
20 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
21 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28
22 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
23 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15
24 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15
25 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
26 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
27 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
28 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
29 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
30 INT235069 Localization of Cdh1 9 0.74 3.81 0.71
31 INT86370 Regulation of CDH1 10 0.54 13.89 0.7
32 INT116007 Negative_regulation of Mavs 1 0.03 0.08 0.69
33 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66
34 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57
35 INT84573 Regulation of Mavs 1 0.01 1.37 0.49
36 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48
37 INT166728 Regulation of MAVS 1 0.32 0.15 0.44
38 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42
39 INT346479 Positive_regulation of DDX58 1 0.06 5.3 0.42
40 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
41 INT221178 Positive_regulation of Gene_expression of Flna 1 0.39 0 0.38
42 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
43 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
44 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35
45 INT163489 Binding of CDH1 13 0.19 8.63 0.35
46 INT127871 Regulation of Gene_expression of CDH1 4 0.44 2.34 0.34
47 INT181918 Positive_regulation of SMAD3 6 0.35 2.62 0.31
48 INT346492 Protein_catabolism of MAVS 1 0.06 1.74 0.31
49 INT140795 Positive_regulation of Gene_expression of Smad3 3 0.48 3.16 0.3
50 INT262797 Regulation of Gene_expression of Smad3 2 0.34 2.27 0.25
51 INT234858 Binding of Cdh1 11 0.47 4.58 0.22
52 INT215000 Transcription of Cdh1 4 0.40 1.17 0.22
53 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
54 INT254701 Transcription of CDH1 6 0.67 2.5 0.17
55 INT157797 Negative_regulation of Phosphorylation of Smad3 3 0.40 0.95 0.17
56 INT204974 Positive_regulation of Mavs 1 0.02 3.77 0.16
57 INT204989 Gene_expression of Mavs 3 0.02 0.86 0.15
58 INT346493 Binding of MAVS 1 0.03 0.54 0.15
59 INT164160 Localization of CDH1 8 0.66 3.39 0.14
60 INT158903 Gene_expression of Smad3 2 0.56 0.54 0.13
61 INT158890 Negative_regulation of Gene_expression of Smad3 1 0.42 0.13 0.13
62 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12
63 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
64 INT296622 Positive_regulation of Gene_expression of Cdh1 3 0.52 2.24 0.09
65 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09
66 INT276619 Negative_regulation of Transcription of Cdh1 1 0.24 0.57 0.09
67 INT305385 Negative_regulation of Localization of FLNA 1 0.16 0.79 0.08
68 INT217383 Regulation of Regulation of Mavs 1 0.01 0.79 0.08
69 INT251364 Negative_regulation of Gene_expression of Cdh1 4 0.32 1.02 0.07
70 INT265317 Negative_regulation of Gene_expression of Smad3 2 0.41 0.9 0.06
71 INT269223 Positive_regulation of Localization of CDH1 1 0.38 0.84 0.06
72 INT349912 Negative_regulation of Negative_regulation of Cdh1 1 0.42 1.04 0.05
73 INT290325 Binding of DDX58 1 0.04 0.52 0.05
74 INT217374 Positive_regulation of Regulation of Mavs 1 0.01 0.37 0.05
75 INT178278 Regulation of Positive_regulation of FLNA 1 0.04 0.4 0.05
76 INT189881 Binding of Cdh1 6 0.36 1.24 0.04
77 INT262799 Localization of Smad3 6 0.56 2.09 0.04
78 INT251361 Transcription of Cdh1 1 0.36 0 0.04
79 INT349906 Negative_regulation of Localization of Cdh1 1 0.42 0.37 0.04
80 INT184722 Positive_regulation of Smad3 3 0.47 1.22 0.03
81 INT236523 Binding of Flna 3 0.30 0.45 0.03
82 INT271419 Localization of SMAD3 2 0.11 0.13 0.03
83 INT204980 Regulation of Gene_expression of Mavs 1 0.01 0.3 0.03
84 INT287933 Negative_regulation of Binding of CDH1 1 0.03 0.65 0.03
85 INT254812 Positive_regulation of Phosphorylation of Smad3 1 0.25 0.94 0.03
86 INT254805 Transcription of Smad3 1 0.28 0.76 0.03
87 INT346490 Phosphorylation of DDX58 1 0.07 1.03 0.03
88 INT287949 Positive_regulation of Positive_regulation of CDH1 3 0.06 1.4 0
89 INT276544 Gene_expression of Flna 3 0.63 1.97 0
90 INT251359 Regulation of Cdh1 2 0.34 0.47 0
91 INT189878 Localization of Cdh1 2 0.56 0.34 0
92 INT276523 Negative_regulation of Gene_expression of Flna 2 0.48 0.8 0
93 INT265337 Binding of Smad3 2 0.35 1 0
94 INT263281 Negative_regulation of Transcription of CDH1 2 0.41 1.84 0
95 INT251362 Regulation of Gene_expression of Cdh1 2 0.46 0.4 0
96 INT269913 Positive_regulation of Binding of Smad3 1 0.34 0.3 0
97 INT218693 Negative_regulation of Phosphorylation of Smad3 1 0.19 0.32 0
98 INT298446 Negative_regulation of Negative_regulation of CDH1 1 0.15 0.59 0
99 INT329784 Gene_expression of SMAD3 1 0.31 0.41 0
100 INT350778 Regulation of Binding of CDH1 1 0.02 0.29 0
101 INT268384 Positive_regulation of Phosphorylation of SMAD3 1 0.29 1.22 0
102 INT189879 Positive_regulation of Binding of Cdh1 1 0.08 0.15 0
103 INT301987 Negative_regulation of Positive_regulation of Cdh1 1 0.07 1.28 0
104 INT312313 Protein_catabolism of Cdh1 1 0.75 0.21 0
105 INT287950 Negative_regulation of Positive_regulation of CDH1 1 0.03 0.56 0
106 INT259156 Protein_catabolism of CDH1 1 0.16 0.38 0
107 INT346315 Negative_regulation of Regulation of CDH1 1 0.04 0.47 0
108 INT269873 Positive_regulation of Negative_regulation of Smad3 1 0.34 0.31 0
109 INT255171 Negative_regulation of Binding of FLNA 1 0.14 0.39 0
110 INT349911 Regulation of Negative_regulation of Cdh1 1 0.44 0.23 0
111 INT214620 Regulation of Localization of FLNA 1 0.02 0.46 0
112 INT268382 Phosphorylation of SMAD3 1 0.34 0.6 0
113 INT324055 Regulation of Transcription of Cdh1 1 0.09 0.49 0
114 INT273927 Transcription of Mavs 1 0.00 0 0
115 INT189883 Negative_regulation of Localization of Cdh1 1 0.07 0.06 0
116 INT296611 Positive_regulation of Negative_regulation of Cdh1 1 0.11 0.78 0
117 INT254809 Positive_regulation of Transcription of Smad3 1 0.25 0.24 0
118 INT269224 Regulation of Transcription of CDH1 1 0.20 0.86 0
119 INT310014 Phosphorylation of Cdh1 1 0.16 0.24 0
120 INT214621 Regulation of Gene_expression of FLNA 1 0.02 1.09 0
121 INT301989 Positive_regulation of Binding of Cdh1 1 0.08 0.42 0
122 INT337958 Localization of Flna 1 0.61 0.43 0
123 INT349904 Regulation of Localization of Cdh1 1 0.44 0.05 0
124 INT337474 Positive_regulation of Binding of CDH1 1 0.07 0.54 0
125 INT268363 Binding of SMAD3 1 0.20 0.56 0
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