GO:0042994

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Name cytoplasmic sequestering of transcription factor
Categary Process
Go Slim No
Go Link GO:0042994
Unique Molecular Interactions 90
Total Molecular Interactions 145
Total Single Events 830
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytoplasmic sequestering of transcription factor. They are ordered first by their pain relevance and then by number of times they were reported for cytoplasmic sequestering of transcription factor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
2 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
3 INT33135 Binding of NFKBIL1 and PRL 1 0.09 0.29 1.01
4 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
5 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
6 INT6409 Binding of NFKBIL1 and Oprm1 1 0.00 0 0.8
7 INT6408 Binding of NFKBIL1 and Ap1m2 1 0.00 0 0.8
8 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
9 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
10 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
11 INT233669 gr Positive_regulation of Transcription of Nfkbia 1 0.26 0.33 0.64
12 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 0.43 0.1 0.62
13 INT2686 Binding of Thra and SGSM3 1 0.36 0.1 0.61
14 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
15 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
16 INT77218 Binding of NFKBIL1 and NKIRAS2 1 0.00 0.27 0.51
17 INT87934 Phosphorylation of Nfkbia Positive_regulation of Nfkb1 1 0.02 0.1 0.45
18 INT87936 Nfkbia Positive_regulation of Nfkb1 1 0.03 0.1 0.44
19 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4
20 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
21 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29
22 INT143724 Binding of Ikbkg and Nfkbia 1 0.02 0.79 0.29
23 INT143723 Positive_regulation of Binding of Ikbkg and Nfkbia 1 0.02 0.8 0.29
24 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28
25 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
26 INT80873 Positive_regulation of Nfkb1 Positive_regulation of Protein_catabolism of Nfkbia 2 0.01 0.58 0.27
27 INT72223 Binding of NFKBIL1 and EMID1 1 0.00 0 0.26
28 INT108878 ZNF236 Regulation of Protein_catabolism of Nfkbia 1 0.00 0.38 0.26
29 INT108880 ZNF236 Regulation of Gene_expression of Nfkbia 1 0.00 0.38 0.26
30 INT108877 ZNF236 Regulation of Phosphorylation of Nfkbia 1 0.00 0.38 0.26
31 INT108881 ZNF236 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.26
32 INT72231 Negative_regulation of Binding of NFKBIL1 and BTRC 1 0.00 0 0.24
33 INT144241 CGA Negative_regulation of Phosphorylation of NFKBIA 1 0.10 0.34 0.22
34 INT144244 TNF Positive_regulation of Protein_catabolism of NFKBIA 1 0.28 0.34 0.22
35 INT144253 TNF Positive_regulation of Phosphorylation of NFKBIA 1 0.39 0.34 0.22
36 INT144247 CGA Positive_regulation of Protein_catabolism of NFKBIA 1 0.11 0.34 0.22
37 INT144243 CGA Positive_regulation of Phosphorylation of NFKBIA 1 0.11 0.34 0.22
38 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
39 INT101812 Binding of KEAP1 and Positive_regulation of Gene_expression of GCLC 1 0.54 0.1 0.19
40 INT159788 Tnf Positive_regulation of Phosphorylation of Nfkbia 1 0.01 0.39 0.19
41 INT319663 Binding of Nfe2l2 and Keap1 1 0.40 2.83 0.17
42 INT319680 Keap1 Negative_regulation of Positive_regulation of Nfe2l2 1 0.36 0.93 0.17
43 INT139790 PRSS53 Negative_regulation of Phosphorylation of NFKBIA 1 0.01 0.9 0.11
44 INT306265 Binding of NFKB1 and NFKBIA 1 0.21 0.48 0.11
45 INT139789 TNFAIP8 Positive_regulation of Phosphorylation of NFKBIA 1 0.02 0.89 0.11
46 INT139788 TNFAIP8 Positive_regulation of NFKBIA 1 0.01 0.88 0.11
47 INT261379 Nsdhl Positive_regulation of Thra 1 0.07 1.12 0.11
48 INT313308 Binding of SQSTM1 and KEAP1 1 0.46 1.16 0.1
49 INT313301 SQSTM1 Regulation of Protein_catabolism of KEAP1 1 0.43 0.58 0.1
50 INT263449 Binding of NFKBIA and TBK1 1 0.07 0.2 0.1
51 INT319672 Nfe2l2 Regulation of Binding of Keap1 1 0.23 0.46 0.09
52 INT263450 NFKB2 Positive_regulation of Protein_catabolism of NFKBIA 1 0.17 0.17 0.09
53 INT131598 Keap1 Negative_regulation of Nfe2l2 2 0.65 1.27 0.08
54 INT131130 Binding of PKD1 and Krt16 1 0.01 1 0.08
55 INT101807 Gene_expression of KEAP1 Negative_regulation of Positive_regulation of GCLC 1 0.46 0 0.08
56 INT4580 Positive_regulation of Thra Positive_regulation of Babr 1 0.00 0 0.07
57 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06
58 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
59 INT161532 Tlr4 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.76 0.03
60 INT161531 Nfkbia Regulation of Gene_expression of Tlr4 1 0.01 0.75 0.03
61 INT161534 Tlr4 Positive_regulation of Phosphorylation of Nfkbia 1 0.00 0.77 0.03
62 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0
63 INT315265 Eri1 Negative_regulation of Keap1 1 0.01 0.26 0
64 INT319668 Keap1 Regulation of Nfe2l2 1 0.52 0.84 0
65 INT245158 AD5 Regulation of PKD1 1 0.00 0.44 0
66 INT313293 Binding of KEAP1 and GOPC 1 0.04 0.24 0
67 INT300664 Binding of Gla and Thra 1 0.08 0 0
68 INT313298 Negative_regulation of SQSTM1 Positive_regulation of KEAP1 1 0.39 0.39 0
69 INT315262 Negative_regulation of Keap1 Negative_regulation of Gene_expression of Nfe2l2 1 0.30 0.48 0
70 INT315260 Eri1 Regulation of Keap1 1 0.00 0.48 0
71 INT246061 KEAP1 Regulation of Positive_regulation of NFE2L2 1 0.34 0 0
72 INT246058 Binding of KEAP1 and Positive_regulation of NFE2L2 1 0.38 0 0
73 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
74 INT319692 Binding of Keap1 and Gadd45gip1 1 0.35 0.18 0
75 INT315270 Rela Positive_regulation of Negative_regulation of Keap1 1 0.10 0.63 0
76 INT319670 Negative_regulation of Binding of Nfe2l2 and Keap1 1 0.36 0.44 0
77 INT215414 KEAP1 Regulation of Regulation of NFE2L2 1 0.02 0.19 0
78 INT313299 Negative_regulation of Binding of NFE2L2 and KEAP1 1 0.24 0.14 0
79 INT197544 Binding of KEAP1 and KLHL2 1 0.02 0.43 0
80 INT319662 Gadd45gip1 Negative_regulation of Keap1 1 0.42 0.66 0
81 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0
82 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
83 INT313296 Binding of KEAP1 and PGAM5 1 0.11 0.15 0
84 INT319669 Binding of Keap1 and Gopc 1 0.08 0 0
85 INT164909 IL33 Positive_regulation of Phosphorylation of NFKBIA 1 0.53 0.05 0
86 INT319676 Gadd45gip1 Regulation of Keap1 1 0.27 0.36 0
87 INT313310 KEAP1 Regulation of Gene_expression of SQSTM1 1 0.43 0.35 0
88 INT313311 SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.45 0 0
89 INT313306 KEAP1 Positive_regulation of SPARC 1 0.02 0.37 0
90 INT313294 Negative_regulation of SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.39 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytoplasmic sequestering of transcription factor. They are ordered first by their pain relevance and then by number of times they were reported in cytoplasmic sequestering of transcription factor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13363 Binding of NFKBIL1 23 0.08 2.65 13.09
2 INT81538 Phosphorylation of Nfkbia 27 0.62 8.86 10.49
3 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62
4 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24
5 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 21 0.54 8.92 7.38
6 INT93481 Negative_regulation of Protein_catabolism of Nfkbia 14 0.39 7.24 7.21
7 INT88498 Protein_catabolism of Nfkbia 14 0.82 6.94 7.1
8 INT81541 Negative_regulation of Nfkbia 12 0.51 5.73 6.79
9 INT50070 Negative_regulation of NFKBIL1 14 0.48 3.76 5.92
10 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
11 INT81535 Negative_regulation of Phosphorylation of Nfkbia 15 0.44 5.74 5.18
12 INT143234 Gene_expression of Nfkbia 10 0.62 5.2 5.02
13 INT88496 Positive_regulation of Protein_catabolism of Nfkbia 8 0.53 3.05 4.78
14 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73
15 INT131253 Positive_regulation of Gene_expression of Nfkbia 4 0.41 3.28 4.71
16 INT87210 Positive_regulation of Nfkbia 9 0.61 3.89 4.35
17 INT81543 Positive_regulation of Phosphorylation of Nfkbia 7 0.37 2.51 4.1
18 INT5996 Positive_regulation of NFKBIL1 4 0.12 1.24 4.1
19 INT108868 Transcription of Nfkbia 2 0.57 2.91 4.03
20 INT13362 Gene_expression of NFKBIL1 12 0.59 3.79 3.99
21 INT2897 Positive_regulation of Thra 20 0.45 5.17 3.01
22 INT233606 Transcription of Nfkbia 1 0.66 1.55 2.71
23 INT93401 Positive_regulation of Protein_catabolism of Nfkbia 11 0.46 3.89 2.7
24 INT107968 Positive_regulation of NFKBIA 9 0.46 5.27 2.69
25 INT47974 Negative_regulation of Protein_catabolism of NFKBIA 7 0.49 2.38 2.69
26 INT108869 Localization of Nfkbia 5 0.56 1.04 2.63
27 INT122003 Phosphorylation of NFKBIA 9 0.59 5.44 2.51
28 INT54081 Regulation of NFKBIL1 5 0.04 1.46 2.28
29 INT129318 Negative_regulation of NFKBIA 10 0.38 6.19 2.02
30 INT26317 Gene_expression of NFKBIA 5 0.45 2.97 1.96
31 INT56080 Transcription of NFKBIA 2 0.40 2.16 1.93
32 INT151269 Positive_regulation of Localization of Nfkbia 1 0.37 0 1.86
33 INT58605 Positive_regulation of Binding of NFKBIL1 1 0.01 0 1.73
34 INT126236 Positive_regulation of Positive_regulation of NFKBIA 4 0.46 2.18 1.69
35 INT47972 Positive_regulation of Protein_catabolism of NFKBIA 5 0.46 2.09 1.53
36 INT233612 Regulation of Transcription of Nfkbia 1 0.36 0.55 1.43
37 INT87215 Localization of Nfkbia 5 0.69 1.64 1.39
38 INT233638 Positive_regulation of Transcription of Nfkbia 1 0.56 1.01 1.33
39 INT131254 Positive_regulation of Transcription of Nfkbia 1 0.36 0.99 1.28
40 INT2681 Binding of Thra 11 0.32 5.98 1.27
41 INT2682 Regulation of Thra 4 0.55 0.49 1.21
42 INT166013 Positive_regulation of Gene_expression of NFKBIA 2 0.32 1.15 1.2
43 INT19277 Gene_expression of Thra 4 0.58 0.68 1.1
44 INT55216 Negative_regulation of Positive_regulation of NFKBIL1 1 0.02 0 1.09
45 INT59667 Regulation of Positive_regulation of NFKBIL1 1 0.01 0.45 1.07
46 INT65029 Negative_regulation of Binding of NFKBIL1 2 0.01 0 1.06
47 INT129726 Regulation of Nfkbia 2 0.06 1.63 1.05
48 INT107971 Regulation of NFKBIA 3 0.24 2.03 1.04
49 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
50 INT81542 Regulation of Protein_catabolism of Nfkbia 2 0.04 0.43 1.02
51 INT143235 Positive_regulation of Gene_expression of Nfkbia 2 0.56 0.97 1.01
52 INT124198 Negative_regulation of Nfkbia 4 0.37 2.58 0.97
53 INT81540 Positive_regulation of Nfkbia 4 0.22 1.37 0.92
54 INT143714 Phosphorylation of Nfkbia 4 0.64 2.94 0.87
55 INT143720 Negative_regulation of Phosphorylation of Nfkbia 3 0.33 2.68 0.83
56 INT154654 Positive_regulation of Keap1 4 0.68 1.55 0.82
57 INT13329 Localization of NFKBIL1 3 0.69 0 0.82
58 INT159548 Regulation of Protein_catabolism of Nfkbia 1 0.18 0.62 0.82
59 INT68469 Positive_regulation of Gene_expression of NFKBIL1 1 0.00 0.51 0.79
60 INT233630 Regulation of Nfkbia 1 0.42 0.27 0.76
61 INT233646 Regulation of Localization of Nfkbia 1 0.42 0.27 0.76
62 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
63 INT95298 Negative_regulation of Gene_expression of Nfkbia 2 0.38 0.62 0.71
64 INT81533 Negative_regulation of Negative_regulation of Nfkbia 1 0.04 0.36 0.7
65 INT143719 Negative_regulation of Gene_expression of Nfkbia 2 0.43 1.31 0.68
66 INT166019 Regulation of Gene_expression of NFKBIA 1 0.05 0.64 0.65
67 INT167742 Negative_regulation of Keap1 14 0.55 9.16 0.63
68 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
69 INT122004 Negative_regulation of Phosphorylation of NFKBIA 3 0.41 1.59 0.58
70 INT56076 Negative_regulation of Protein_catabolism of NFKBIL1 2 0.22 0.86 0.57
71 INT263482 Positive_regulation of Transcription of NFKBIA 1 0.39 0.61 0.57
72 INT56081 Protein_catabolism of NFKBIL1 2 0.37 0.85 0.56
73 INT131597 Gene_expression of Keap1 17 0.76 6.65 0.55
74 INT25362 Binding of NFKBIA 4 0.26 2.52 0.55
75 INT101815 Binding of KEAP1 6 0.44 5.29 0.39
76 INT13330 Transcription of NFKBIL1 1 0.59 0 0.38
77 INT154653 Negative_regulation of Positive_regulation of Keap1 2 0.36 0.59 0.34
78 INT132627 Binding of Nfkbia 1 0.03 0.41 0.31
79 INT101821 Localization of KEAP1 4 0.71 0.93 0.28
80 INT167737 Positive_regulation of Negative_regulation of Keap1 2 0.47 1.6 0.27
81 INT56079 Negative_regulation of Transcription of NFKBIA 1 0.05 0.54 0.26
82 INT154656 Regulation of Keap1 2 0.46 1.9 0.25
83 INT108867 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.25
84 INT315230 Binding of Keap1 5 0.43 3.91 0.23
85 INT197575 Protein_catabolism of KEAP1 4 0.91 3.44 0.23
86 INT101820 Negative_regulation of KEAP1 20 0.58 18.79 0.19
87 INT151129 Negative_regulation of Localization of Nfkbia 1 0.30 0.31 0.19
88 INT154558 Regulation of Phosphorylation of Nfkbia 1 0.00 0.33 0.17
89 INT131596 Positive_regulation of Gene_expression of Keap1 6 0.52 2.09 0.16
90 INT87209 Negative_regulation of Positive_regulation of Nfkbia 1 0.31 0.15 0.16
91 INT87213 Positive_regulation of Localization of Nfkbia 1 0.34 0.15 0.16
92 INT199521 Protein_catabolism of PKD1 2 0.96 0.39 0.15
93 INT101831 Gene_expression of KEAP1 21 0.77 10.82 0.12
94 INT197563 Regulation of KEAP1 10 0.56 3.18 0.11
95 INT313329 Positive_regulation of Binding of KEAP1 1 0.46 0.44 0.11
96 INT139798 Positive_regulation of Phosphorylation of NFKBIA 1 0.04 0.88 0.11
97 INT167741 Localization of Keap1 3 0.70 1.35 0.1
98 INT101824 Positive_regulation of Localization of KEAP1 2 0.57 0 0.09
99 INT101830 Negative_regulation of Localization of KEAP1 1 0.48 0 0.09
100 INT177630 Regulation of Gene_expression of NFKBIL1 1 0.37 0.92 0.09
101 INT319632 Regulation of Binding of Keap1 1 0.40 0.45 0.09
102 INT197562 Positive_regulation of KEAP1 16 0.63 6.78 0.08
103 INT101827 Positive_regulation of Gene_expression of KEAP1 5 0.69 2.67 0.08
104 INT319614 Protein_catabolism of Keap1 1 0.89 0.28 0.07
105 INT286583 Localization of PKD2 1 0.35 0.17 0.06
106 INT211006 Binding of PKD1 6 0.22 2.69 0.05
107 INT261879 Binding of PKD2 3 0.13 2.59 0.05
108 INT197560 Negative_regulation of Gene_expression of KEAP1 5 0.58 3.12 0
109 INT315237 Negative_regulation of Gene_expression of Keap1 4 0.38 1.55 0
110 INT315240 Regulation of Gene_expression of Keap1 3 0.40 1.03 0
111 INT175892 Negative_regulation of PKD1 2 0.42 1.03 0
112 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
113 INT315231 Negative_regulation of Binding of Keap1 2 0.38 0.42 0
114 INT210870 Gene_expression of Thra 1 0.35 0.23 0
115 INT315238 Negative_regulation of Regulation of Keap1 1 0.32 0.68 0
116 INT315222 Transcription of Keap1 1 0.52 0.6 0
117 INT315227 Regulation of Regulation of Keap1 1 0.34 0.61 0
118 INT313325 Regulation of Gene_expression of KEAP1 1 0.41 0 0
119 INT197556 Positive_regulation of Protein_catabolism of KEAP1 1 0.50 0.74 0
120 INT293537 Negative_regulation of Gene_expression of Thra 1 0.24 0.11 0
121 INT197574 Positive_regulation of Negative_regulation of KEAP1 1 0.50 1.15 0
122 INT46503 Positive_regulation of Negative_regulation of Thra 1 0.07 0 0
123 INT315233 Regulation of Negative_regulation of Keap1 1 0.34 0.49 0
124 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
125 INT175898 Positive_regulation of PKD1 1 0.50 1.24 0
126 INT261880 Negative_regulation of Binding of PKD1 1 0.16 0.6 0
127 INT319639 Positive_regulation of Binding of Keap1 1 0.45 0.06 0
128 INT315234 Negative_regulation of Negative_regulation of Keap1 1 0.32 0.48 0
129 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
130 INT293535 Regulation of Gene_expression of Thra 1 0.26 0.28 0
131 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
132 INT313316 Regulation of Positive_regulation of KEAP1 1 0.41 0 0
133 INT197555 Transcription of KEAP1 1 0.71 2.33 0
134 INT175896 Transcription of PKD1 1 0.53 1.22 0
135 INT175890 Negative_regulation of Gene_expression of PKD1 1 0.42 0.11 0
136 INT315225 Positive_regulation of Transcription of Keap1 1 0.38 0.26 0
137 INT197570 Negative_regulation of Transcription of KEAP1 1 0.58 1.19 0
138 INT313317 Positive_regulation of Positive_regulation of KEAP1 1 0.46 0 0
139 INT214908 Positive_regulation of Gene_expression of PKD1 1 0.35 0.86 0
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