GO:0043009

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Name chordate embryonic development
Categary Process
Go Slim No
Go Link GO:0043009
Unique Molecular Interactions 47
Total Molecular Interactions 59
Total Single Events 311
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chordate embryonic development. They are ordered first by their pain relevance and then by number of times they were reported for chordate embryonic development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
2 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
3 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
4 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
5 INT56092 FGFR1 Positive_regulation of Transcription of SERPINE1 1 0.29 0.41 0.29
6 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
7 INT154044 Gm6983 Positive_regulation of Localization of FGFR1 1 0.00 0.06 0.28
8 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
9 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
10 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
11 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18
12 INT125550 FGFR1 Negative_regulation of Cyp2e1 1 0.02 0.06 0.18
13 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18
14 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
15 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
16 INT125551 Binding of FGFR1 and Cyp2e1 1 0.02 0.07 0.13
17 INT125549 Binding of CYP2B6 and FGFR1 1 0.00 0.07 0.13
18 INT117838 FGFR1 Regulation of FGF2 1 0.33 0.17 0.09
19 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
20 INT243783 FGFR1 Positive_regulation of FGF20 1 0.05 0 0.04
21 INT267093 FGFR1 Positive_regulation of Gene_expression of P2rx1 1 0.03 0.2 0.03
22 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03
23 INT267092 FGFR1 Positive_regulation of Gene_expression of P2rx6 1 0.04 0.2 0.03
24 INT267094 FGFR1 Negative_regulation of Gene_expression of P2rx6 1 0.04 0.21 0.03
25 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
26 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
27 INT260268 Binding of FGF2 and FGFR1 1 0.46 0.94 0
28 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
29 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
30 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0
31 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
32 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
33 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
34 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
35 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
36 INT219349 FGFR1 Positive_regulation of Gene_expression of MMP11 1 0.09 0.55 0
37 INT219354 FGFR1 Positive_regulation of Gene_expression of PAK1 1 0.10 0.55 0
38 INT267091 FGFR1 Positive_regulation of Negative_regulation of P2rx6 1 0.04 0 0
39 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
40 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
41 INT219385 FGFR1 Positive_regulation of Sympk 1 0.00 0.53 0
42 INT219351 FGFR1 Positive_regulation of Gene_expression of SMARCB1 1 0.10 0.55 0
43 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0
44 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0
45 INT326793 FGFR1 Positive_regulation of Gene_expression of ST8SIA2 1 0.00 0.07 0
46 INT260265 Binding of FGF1 and FGFR1 1 0.45 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chordate embryonic development. They are ordered first by their pain relevance and then by number of times they were reported in chordate embryonic development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56
2 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36
3 INT97903 Negative_regulation of FGFR1 16 0.17 5.6 4.57
4 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
5 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
6 INT142908 Localization of FGFR1 18 0.38 11.46 2.57
7 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
8 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
9 INT74977 Binding of FGFR1 6 0.41 4.66 1.02
10 INT97899 Positive_regulation of Gene_expression of FGFR1 7 0.62 5.99 0.9
11 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
12 INT99239 Negative_regulation of Negative_regulation of FGFR1 1 0.06 0.3 0.69
13 INT97901 Regulation of FGFR1 5 0.24 2.56 0.55
14 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
15 INT97904 Negative_regulation of Gene_expression of FGFR1 1 0.38 0.92 0.55
16 INT267122 Negative_regulation of Positive_regulation of FGFR1 1 0.03 1.03 0.44
17 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
18 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
19 INT154043 Positive_regulation of Localization of FGFR1 1 0.02 0.06 0.28
20 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
21 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
22 INT172486 Regulation of Localization of FGFR1 2 0.21 0.52 0.19
23 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
24 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
25 INT89690 Binding of Brca2 2 0.37 1.8 0.18
26 INT89689 Binding of Brca1 2 0.37 2.55 0.18
27 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
28 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
29 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
30 INT238986 Protein_catabolism of FGFR1 1 0.18 0.2 0.1
31 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
32 INT234186 Localization of BRCA2 2 0.69 1.48 0.07
33 INT187589 Positive_regulation of Gene_expression of Brca1 2 0.55 1.93 0.03
34 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
35 INT267088 Positive_regulation of Positive_regulation of FGFR1 1 0.07 0.22 0.03
36 INT259116 Transcription of BRCA1 3 0.44 3.77 0
37 INT167536 Positive_regulation of BRCA2 2 0.49 0.29 0
38 INT212457 Phosphorylation of Brca1 2 0.51 0.96 0
39 INT234191 Positive_regulation of Localization of BRCA2 1 0.46 0.68 0
40 INT187580 Positive_regulation of Brca1 1 0.10 1.17 0
41 INT314708 Gene_expression of Brca2 1 0.41 1.75 0
42 INT119064 Regulation of Gene_expression of BRCA1 1 0.53 0.05 0
43 INT314707 Regulation of Transcription of Brca2 1 0.27 0.56 0
44 INT314706 Transcription of Brca1 1 0.43 0.53 0
45 INT314705 Transcription of Brca2 1 0.42 0.56 0
46 INT221271 Negative_regulation of Binding of BRCA1 1 0.28 0.93 0
47 INT173224 Regulation of BRCA2 1 0.21 1.3 0
48 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0
49 INT234188 Positive_regulation of Localization of BRCA1 1 0.42 0.68 0
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