GO:0043030

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Name regulation of macrophage activation
Categary Process
Go Slim No
Go Link GO:0043030
Unique Molecular Interactions 41
Total Molecular Interactions 51
Total Single Events 653
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of macrophage activation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of macrophage activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
3 INT261410 Slc7a2 Positive_regulation of Ltp 1 0.06 0.08 1.21
4 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
5 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
6 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6
7 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6
8 INT66769 Negative_regulation of Il1b Positive_regulation of Pla2g10 1 0.04 0.25 0.53
9 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
10 INT195769 MIF Regulation of Gene_expression of TP53I11 1 0.19 1.24 0.47
11 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
12 INT355571 MIF Positive_regulation of IL8 1 0.04 1.05 0.44
13 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
14 INT121364 ZNF398 Negative_regulation of Transcription of MIF 1 0.00 0.9 0.43
15 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
16 INT121365 ZNF398 Negative_regulation of Gene_expression of MIF 1 0.00 0.73 0.38
17 INT355570 MIF Positive_regulation of Gene_expression of IL8 1 0.07 1.11 0.36
18 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
19 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
20 INT355567 IRF6 Positive_regulation of MIF 1 0.01 0.29 0.25
21 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
22 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
23 INT195770 Binding of CPB1 and MIF 1 0.01 0.47 0.15
24 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
25 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
26 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
27 INT197777 Pla2g10 Regulation of Pla2g2a 1 0.02 0.61 0.08
28 INT197776 Pla2g10 Regulation of Pla2g4a 1 0.18 0.61 0.08
29 INT178969 Slc7a2 Regulation of Ins1 1 0.01 0.56 0.05
30 INT178968 Slc7a2 Negative_regulation of Glb1 1 0.02 1.77 0.05
31 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
32 INT190890 Binding of RORA and Grip1 1 0.00 0.09 0
33 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
34 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
35 INT178967 Slc7a2 Regulation of Localization of Ins1 1 0.01 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of macrophage activation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of macrophage activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
2 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78
3 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
4 INT125444 Gene_expression of Rora 5 0.75 3.05 8.97
5 INT117553 Regulation of MIF 10 0.56 12.76 8.67
6 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08
7 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12
8 INT40782 Gene_expression of Slc7a2 10 0.57 4.59 5
9 INT66760 Gene_expression of Pla2g10 8 0.76 4.43 4.83
10 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73
11 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
12 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
13 INT66762 Negative_regulation of Pla2g10 6 0.48 7.8 4.54
14 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
15 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
16 INT123595 Regulation of Snca 7 0.62 4.3 3.06
17 INT163290 Binding of MIF 9 0.31 7.57 2.8
18 INT243350 Binding of CD74 2 0.11 4.86 2.72
19 INT190881 Positive_regulation of Rora 2 0.43 1.76 2.71
20 INT120011 Localization of MIF 6 0.58 5.72 2.6
21 INT118251 Localization of Pla2g10 5 0.73 3.07 2.55
22 INT125442 Negative_regulation of Gene_expression of Rora 5 0.57 2.92 2.54
23 INT197228 Positive_regulation of Gene_expression of Rora 1 0.05 0 2.43
24 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
25 INT118250 Positive_regulation of Gene_expression of Pla2g10 3 0.49 2.47 1.93
26 INT127125 Localization of Snca 6 0.81 8.24 1.88
27 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
28 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
29 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
30 INT40783 Localization of Slc7a2 1 0.62 0 1.25
31 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
32 INT66759 Transcription of Pla2g10 1 0.59 0.41 1.19
33 INT151753 Transcription of Snca 6 0.69 1.99 1.11
34 INT121375 Transcription of MIF 4 0.62 2.85 1.1
35 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
36 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
37 INT121369 Negative_regulation of Gene_expression of MIF 3 0.50 2.48 0.92
38 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
39 INT124246 Binding of Snca 10 0.37 6.53 0.9
40 INT121376 Negative_regulation of Transcription of MIF 3 0.37 2.26 0.87
41 INT217990 Negative_regulation of Slc7a2 1 0.41 2.16 0.85
42 INT197772 Positive_regulation of Pla2g10 1 0.38 5.94 0.85
43 INT33195 Positive_regulation of Slc7a2 2 0.23 0 0.82
44 INT135816 Transcription of Slc7a2 1 0.54 0 0.81
45 INT135819 Positive_regulation of Transcription of Slc7a2 1 0.38 0 0.81
46 INT135821 Negative_regulation of Transcription of Slc7a2 1 0.32 0 0.81
47 INT197226 Regulation of Gene_expression of Rora 1 0.04 0 0.71
48 INT66763 Negative_regulation of Transcription of Pla2g10 1 0.48 0.22 0.61
49 INT66765 Negative_regulation of Gene_expression of Pla2g10 1 0.48 0.27 0.58
50 INT167595 Gene_expression of RORA 2 0.05 1.51 0.54
51 INT197215 Regulation of Regulation of Rora 1 0.03 0.08 0.46
52 INT197227 Regulation of Rora 1 0.06 0.08 0.46
53 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
54 INT197214 Binding of Rora 1 0.04 0.09 0.39
55 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
56 INT197775 Regulation of Pla2g10 1 0.17 2.26 0.39
57 INT62874 Gene_expression of CD74 1 0.00 0.64 0.37
58 INT169628 Binding of SNCA 4 0.47 3.53 0.36
59 INT343973 Localization of SNCA 1 0.63 0.07 0.3
60 INT121374 Regulation of Gene_expression of MIF 2 0.39 1.01 0.29
61 INT142052 Binding of Snca 4 0.47 1.02 0.22
62 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
63 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
64 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
65 INT217991 Regulation of Slc7a2 1 0.19 0.44 0.16
66 INT157084 Localization of Snca 1 0.51 0.17 0.16
67 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
68 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
69 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
70 INT145362 Positive_regulation of RORA 3 0.49 0.61 0.14
71 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09
72 INT125443 Negative_regulation of Rora 1 0.57 0.74 0.08
73 INT292946 Positive_regulation of Localization of Snca 1 0.50 0.52 0.06
74 INT190888 Positive_regulation of Phosphorylation of RORA 1 0.01 0.25 0.06
75 INT190886 Phosphorylation of RORA 1 0.01 0.25 0.06
76 INT50097 Regulation of RORA 2 0.01 0 0
77 INT194148 Positive_regulation of CD74 2 0.27 0.68 0
78 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0
79 INT50098 Negative_regulation of RORA 1 0.02 0 0
80 INT178964 Positive_regulation of Gene_expression of Slc7a2 1 0.10 0.66 0
81 INT190887 Binding of RORA 1 0.00 0.1 0
82 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
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