GO:0043083

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Name synaptic cleft
Categary Component
Go Slim No
Go Link GO:0043083
Unique Molecular Interactions 223
Total Molecular Interactions 323
Total Single Events 3206
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic cleft. They are ordered first by their pain relevance and then by number of times they were reported for synaptic cleft. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17300 Prss12 Positive_regulation of Localization of Acot1 4 0.11 0 3.28
2 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
3 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
4 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
5 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
6 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
7 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
8 INT150455 Binding of Prss12 and Nts 3 0.24 1.42 2.66
9 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
10 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
11 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
12 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
13 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
14 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
15 INT17299 Prss12 Regulation of Localization of Acot1 3 0.05 0 2.07
16 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
17 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
18 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
19 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
20 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
21 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
22 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
23 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
24 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
25 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
26 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
27 INT777 Prss12 Positive_regulation of Prl 1 0.19 0 1.33
28 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
29 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
30 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23
31 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
32 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
33 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
34 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
35 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
36 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
37 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
38 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
39 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
40 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
41 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
42 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
43 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
44 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
45 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
46 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
47 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
48 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
49 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
50 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
51 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
52 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
53 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
54 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
55 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
56 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
57 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
58 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
59 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
60 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
61 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
62 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
63 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
64 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
65 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
66 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
67 INT154258 Binding of Abat and Prss12 1 0.03 0 0.87
68 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
69 INT154257 Binding of Prss12 and Cfp 1 0.02 0 0.87
70 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
71 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
72 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
73 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
74 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
75 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
76 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
77 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
78 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
79 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
80 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
81 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
82 INT784 Prss12 Positive_regulation of Gh1 1 0.06 0 0.7
83 INT783 Prss12 Positive_regulation of Positive_regulation of Oprl1 1 0.05 0 0.7
84 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
85 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
86 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
87 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
88 INT13595 Penk Positive_regulation of Localization of Prss12 1 0.12 0 0.67
89 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
90 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
91 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
92 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
93 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
94 INT780 Prss12 Positive_regulation of Gene_expression of Prl 1 0.14 0 0.65
95 INT781 Prss12 Positive_regulation of Gene_expression of Gnrhr 1 0.10 0 0.65
96 INT40762 Trh Negative_regulation of Prss12 1 0.06 0 0.65
97 INT773 Prss12 Positive_regulation of Gnrhr 1 0.04 0 0.64
98 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
99 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
100 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
101 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
102 INT281079 Binding of Nsf and Gria3 1 0.19 0.05 0.61
103 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
104 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
105 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
106 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
107 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54
108 INT46434 Prss12 Negative_regulation of Prl 1 0.16 0 0.54
109 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
110 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
111 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
112 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51
113 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
114 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5
115 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
116 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
117 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
118 INT283736 Tbs1 Positive_regulation of Grin1 1 0.04 0 0.48
119 INT39076 Prss12 Regulation of Penk 1 0.04 0.44 0.46
120 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
121 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
122 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
123 INT10550 Prss12 Positive_regulation of Localization of Abat 1 0.06 0 0.45
124 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
125 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
126 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43
127 INT10549 Prss12 Regulation of Localization of Abat 1 0.04 0 0.43
128 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
129 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
130 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
131 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
132 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
133 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
134 INT296300 Binding of Grin1 and Kcnip3 1 0.18 0 0.4
135 INT131180 Binding of Grin1 and Oprd1 1 0.24 0 0.39
136 INT39093 Negative_regulation of Prss12 Positive_regulation of Localization of Ren 1 0.10 0 0.37
137 INT39096 Prss12 Negative_regulation of Ren 1 0.12 0 0.37
138 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
139 INT121757 Grin1 Regulation of Gene_expression of Fos 1 0.44 0.44 0.35
140 INT13374 Binding of Grin1 and Ltp 1 0.20 0 0.35
141 INT121758 Grin1 Regulation of Positive_regulation of Fos 1 0.44 0.44 0.35
142 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
143 INT150458 Prss12 Regulation of Helt 1 0.00 0 0.34
144 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
145 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33
146 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
147 INT16382 Binding of Grin1 and Gnmt 1 0.04 0.17 0.32
148 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
149 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
150 INT263749 Binding of Grin2b and Neto1 1 0.38 0 0.3
151 INT46432 Prl Negative_regulation of Prss12 1 0.16 0 0.3
152 INT317571 Grin1 Regulation of Trpv1 1 0.00 0 0.29
153 INT317562 Binding of Grin1 and Gnptab 1 0.00 0 0.29
154 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
155 INT334666 Slc9a1 Positive_regulation of Grin1 1 0.09 0.09 0.27
156 INT46433 Nts Negative_regulation of Prss12 1 0.12 0 0.27
157 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
158 INT310402 Binding of CALM1 and Grin1 1 0.00 0 0.26
159 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
160 INT208123 Hpcal1 Regulation of Grin2b 1 0.10 0 0.21
161 INT263765 Neto1 Regulation of Grin1 1 0.39 0.26 0.2
162 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
163 INT263721 Binding of Grin1 and Neto1 1 0.33 0 0.18
164 INT234303 Gria3 Negative_regulation of Gria4 1 0.36 0 0.16
165 INT238087 Binding of Grin1 and Mmp3 1 0.13 0 0.15
166 INT273238 Grin1 Positive_regulation of Ptprs 1 0.07 0.51 0.14
167 INT8161 Fos Regulation of Gene_expression of Prss12 1 0.07 0.31 0.13
168 INT45518 Prss12 Positive_regulation of Localization of LH 1 0.07 0.36 0.13
169 INT45516 Prss12 Regulation of Regulation of LH 1 0.07 0.36 0.13
170 INT260495 VEGFA Positive_regulation of Grin1 1 0.08 1.08 0.12
171 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
172 INT350343 Csnk2a2 Regulation of Grin1 1 0.11 0.09 0.11
173 INT234302 Negative_regulation of Gria3 Positive_regulation of Swd1 1 0.01 0.47 0.1
174 INT263729 Grin2b Positive_regulation of Gene_expression of Car1 1 0.20 0 0.1
175 INT231301 Prnp Regulation of Regulation of Grin1 1 0.26 0.24 0.08
176 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08
177 INT263725 Neto1 Regulation of Localization of Grin1 1 0.39 0.15 0.08
178 INT263755 Grin1 Regulation of Localization of Grin2b 1 0.27 0.17 0.07
179 INT263782 Grin2a Regulation of Localization of Grin1 1 0.29 0.17 0.07
180 INT263741 Grin2b Regulation of Localization of Dlg4 1 0.17 0.17 0.07
181 INT263761 Grin1 Regulation of Localization of Vamp2 1 0.27 0.17 0.07
182 INT263784 Dlg4 Regulation of Localization of Grin1 1 0.17 0.17 0.07
183 INT263748 Grin1 Regulation of Localization of Gria2 1 0.20 0.17 0.07
184 INT263728 Grin2b Regulation of Localization of Grin1 1 0.27 0.17 0.07
185 INT263723 Grin2b Regulation of Localization of Gria2 1 0.18 0.17 0.07
186 INT263759 Grin1 Regulation of Localization of Grin2a 1 0.29 0.17 0.07
187 INT263742 Grin1 Regulation of Localization of Dlg4 1 0.19 0.17 0.07
188 INT263762 Grin2a Regulation of Localization of Grin2b 1 0.26 0.17 0.07
189 INT263722 Dlg4 Regulation of Localization of Grin2b 1 0.15 0.17 0.07
190 INT263739 Grin2b Regulation of Localization of Vamp2 1 0.24 0.17 0.07
191 INT350345 Tbp Positive_regulation of Positive_regulation of Grin1 1 0.18 0 0.07
192 INT263768 Grin2b Regulation of Localization of Grin2a 1 0.26 0.17 0.07
193 INT263767 Binding of Camk2a and Grin2b 1 0.18 0 0.06
194 INT263770 Rasgrf1 Positive_regulation of Positive_regulation of Grin1 1 0.24 0 0.06
195 INT231300 Positive_regulation of Grin2b Positive_regulation of Prnp 1 0.39 0.16 0.05
196 INT202893 Camk4 Negative_regulation of Grin1 1 0.10 0.17 0.05
197 INT263763 Localization of Neto1 Regulation of Localization of Grin2b 1 0.36 0.18 0.05
198 INT263727 Binding of Grin2b and Rasgrf1 1 0.18 0 0.05
199 INT250073 Grin2a Regulation of Grin2b 1 0.39 0.9 0.05
200 INT263781 Localization of Neto1 Regulation of Localization of Grin1 1 0.39 0.18 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic cleft. They are ordered first by their pain relevance and then by number of times they were reported in synaptic cleft. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
5 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
6 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
7 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
8 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
9 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
10 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
11 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
12 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
13 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
14 INT11246 Binding of Grin1 65 0.48 14.53 36.93
15 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
16 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
17 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
18 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
19 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
20 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
21 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
22 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
23 INT8362 Localization of Prss12 53 0.78 5.09 27
24 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
25 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
26 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
27 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
28 INT16624 Localization of Grin1 38 0.79 8.46 17.15
29 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
30 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
31 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
32 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
33 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
34 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
35 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
36 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
37 INT112103 Binding of Grin1 28 0.48 4.21 12.08
38 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
39 INT10546 Positive_regulation of Prss12 12 0.44 4.57 10.05
40 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
41 INT8360 Positive_regulation of Localization of Prss12 14 0.26 1.72 9.38
42 INT13593 Binding of Prss12 13 0.36 4.35 9.37
43 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
44 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
45 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
46 INT8160 Gene_expression of Prss12 20 0.67 4.83 8.17
47 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
48 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
49 INT135113 Localization of Grin1 18 0.73 3.73 7.69
50 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
51 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
52 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
53 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
54 INT10547 Regulation of Prss12 11 0.41 3.11 5.74
55 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
56 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
57 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
58 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
59 INT13594 Regulation of Localization of Prss12 5 0.30 1.55 4.88
60 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
61 INT53787 Transcription of Prss12 7 0.21 3.29 4.4
62 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
63 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
64 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
65 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
66 INT11661 Negative_regulation of Prss12 7 0.37 0.78 4.16
67 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
68 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
69 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
70 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
71 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
72 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
73 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
74 INT76715 Gene_expression of Gria3 16 0.75 1.89 2.77
75 INT169088 Gene_expression of GRIA3 7 0.76 1.32 2.67
76 INT11892 Gene_expression of ACHE 10 0.68 1.32 2.63
77 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
78 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
79 INT114026 Transcription of Grin1 7 0.67 3.13 2.45
80 INT27338 Regulation of ACHE 6 0.62 1.25 2.38
81 INT73347 Positive_regulation of Positive_regulation of Prss12 1 0.09 1.23 2.38
82 INT114024 Positive_regulation of Transcription of Grin1 1 0.49 1.69 2.37
83 INT14890 Localization of ACHE 5 0.80 0.47 2.21
84 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
85 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
86 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89
87 INT111405 Negative_regulation of Regulation of Grin1 1 0.54 0.09 1.81
88 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
89 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
90 INT8757 Binding of ACHE 10 0.48 5.84 1.72
91 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71
92 INT322821 Binding of GRIA3 1 0.47 2.06 1.67
93 INT14891 Positive_regulation of ACHE 10 0.70 5.37 1.64
94 INT8359 Negative_regulation of Localization of Prss12 2 0.32 0 1.6
95 INT135112 Regulation of Phosphorylation of Grin1 2 0.44 0.3 1.58
96 INT74592 Regulation of Transcription of Grin1 2 0.60 1.05 1.51
97 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
98 INT115355 Regulation of Negative_regulation of Grin1 2 0.23 0.23 1.44
99 INT59040 Regulation of Positive_regulation of Grin1 3 0.27 1.61 1.42
100 INT296265 Regulation of Phosphorylation of Grin2b 2 0.44 1.06 1.4
101 INT119522 Positive_regulation of Gene_expression of Prss12 1 0.60 2.34 1.39
102 INT251602 Regulation of Binding of Grin1 2 0.25 0.05 1.34
103 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
104 INT58567 Negative_regulation of Positive_regulation of Prss12 2 0.21 0 1.21
105 INT96330 Regulation of Regulation of Grin1 2 0.14 0.83 1.2
106 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
107 INT105326 Regulation of Localization of Grin1 3 0.44 0.76 1.16
108 INT322822 Regulation of GRIA3 4 0.61 1.19 1.11
109 INT143091 Positive_regulation of Negative_regulation of Grin2b 2 0.44 0.9 1.09
110 INT291961 Negative_regulation of Regulation of Grin2b 1 0.30 1.65 1.09
111 INT317484 Positive_regulation of Localization of Grin1 1 0.28 0.11 1.07
112 INT58606 Negative_regulation of Binding of Prss12 4 0.20 0 1.01
113 INT135114 Negative_regulation of Localization of Grin1 1 0.41 0.17 1
114 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
115 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85
116 INT143092 Negative_regulation of Negative_regulation of Grin2b 1 0.27 0.33 0.83
117 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74
118 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
119 INT322816 Transcription of GRIA3 2 0.71 0.75 0.7
120 INT121717 Positive_regulation of Negative_regulation of Grin1 2 0.66 0.13 0.69
121 INT322819 Regulation of Binding of GRIA3 1 0.61 1.07 0.68
122 INT139895 Positive_regulation of Gene_expression of GRIN2B 2 0.49 0.9 0.65
123 INT235994 Protein_catabolism of Grin1 2 0.42 0.64 0.63
124 INT147397 Negative_regulation of Binding of Grin2b 1 0.16 0.87 0.63
125 INT122116 Negative_regulation of Transcription of Grin2b 1 0.43 0.34 0.62
126 INT238082 Positive_regulation of Localization of Grin1 2 0.37 0.23 0.61
127 INT230974 Positive_regulation of Gene_expression of GRIA3 2 0.49 0 0.57
128 INT271625 Protein_catabolism of Grin2b 1 0.38 0.26 0.57
129 INT296255 Negative_regulation of Localization of Grin2b 1 0.30 0.16 0.56
130 INT144394 Protein_catabolism of ACHE 1 0.89 0.24 0.53
131 INT271631 Negative_regulation of Localization of Grin1 2 0.32 0.58 0.52
132 INT156378 Regulation of Binding of Grin2b 1 0.28 0.17 0.52
133 INT224806 Negative_regulation of Gria3 2 0.56 1.09 0.5
134 INT163895 Positive_regulation of Phosphorylation of GRIN2B 1 0.09 0.99 0.48
135 INT271632 Negative_regulation of Regulation of Grin2b 2 0.28 1.06 0.47
136 INT250065 Positive_regulation of Localization of Grin2b 1 0.45 0 0.47
137 INT273217 Protein_catabolism of Grin1 1 0.55 1.31 0.43
138 INT352667 Positive_regulation of Transcription of GRIA3 1 0.08 0.39 0.42
139 INT352661 Positive_regulation of GRIA3 1 0.12 0.33 0.41
140 INT170354 Positive_regulation of Binding of Grin1 3 0.49 0 0.38
141 INT11660 Regulation of Negative_regulation of Prss12 1 0.16 0 0.37
142 INT271630 Negative_regulation of Localization of Grin2b 1 0.25 0 0.37
143 INT273225 Regulation of Protein_catabolism of Grin1 1 0.30 1.16 0.36
144 INT250062 Positive_regulation of Transcription of Grin2b 1 0.39 0.47 0.34
145 INT272581 Binding of Gria3 2 0.36 0.29 0.33
146 INT169090 Regulation of Gene_expression of GRIA3 2 0.61 0.46 0.32
147 INT322820 Localization of GRIA3 1 0.74 0.31 0.31
148 INT53816 Negative_regulation of Binding of Grin1 2 0.39 0 0.3
149 INT163897 Negative_regulation of Phosphorylation of GRIN2B 1 0.08 0.39 0.28
150 INT271629 Positive_regulation of Protein_catabolism of Grin2b 1 0.27 0.13 0.28
151 INT255780 Negative_regulation of Negative_regulation of ACHE 2 0.43 1.28 0.24
152 INT313623 Regulation of Localization of Grin2b 1 0.32 0 0.24
153 INT273223 Positive_regulation of Protein_catabolism of Grin2b 1 0.40 0.73 0.23
154 INT208117 Positive_regulation of Binding of Grin2b 1 0.46 0 0.23
155 INT273229 Protein_catabolism of Grin2b 1 0.57 1.29 0.22
156 INT322824 Regulation of Regulation of GRIA3 1 0.44 0.42 0.2
157 INT35620 Positive_regulation of Negative_regulation of ACHE 1 0.48 0 0.17
158 INT238075 Regulation of Protein_catabolism of Grin1 1 0.13 0 0.16
159 INT238070 Positive_regulation of Protein_catabolism of Grin1 1 0.24 0 0.16
160 INT273228 Positive_regulation of Protein_catabolism of Grin1 1 0.28 0.31 0.14
161 INT281212 Negative_regulation of Negative_regulation of Grin1 1 0.08 0.06 0.12
162 INT270427 Negative_regulation of Binding of ACHE 2 0.42 1.82 0.11
163 INT234296 Phosphorylation of Gria3 1 0.68 0 0.1
164 INT234298 Positive_regulation of Negative_regulation of Gria3 1 0.48 0.47 0.1
165 INT186574 Negative_regulation of Gene_expression of ACHE 1 0.37 0.51 0.08
166 INT231288 Positive_regulation of Regulation of Grin1 1 0.42 0.24 0.08
167 INT220701 Regulation of Negative_regulation of ACHE 2 0.25 1.06 0
168 INT307610 Positive_regulation of Phosphorylation of ACHE 1 0.08 0.2 0
169 INT19017 Negative_regulation of Positive_regulation of ACHE 1 0.42 0.09 0
170 INT307614 Phosphorylation of ACHE 1 0.14 0.2 0
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