GO:0043085

From wiki-pain
Jump to: navigation, search
Name positive regulation of catalytic activity
Categary Process
Go Slim No
Go Link GO:0043085
Unique Molecular Interactions 1005
Total Molecular Interactions 1348
Total Single Events 12844
Pain Genes Associated 65

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of catalytic activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of catalytic activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
2 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
3 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
4 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
5 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
6 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
7 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
8 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
9 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
10 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
11 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
12 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
13 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
14 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
15 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
16 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
17 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 0.12 0.07 1.21
18 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
19 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
20 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
21 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
22 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
23 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
24 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
25 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
26 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
27 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
28 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
29 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
30 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
31 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
32 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
33 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
34 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
35 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
36 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
37 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
38 INT182203 Binding of CXCL1 and CXCR2 1 0.14 1.25 0.95
39 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
40 INT182199 Binding of CXCR5 and CXCL1 1 0.16 1.24 0.94
41 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
42 INT182195 Binding of CXCL1 and CXCR4 1 0.13 1.25 0.94
43 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
44 INT182189 Binding of CXCL1 and CXCL13 1 0.14 1.24 0.93
45 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
46 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
47 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
48 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
49 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
50 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
51 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
52 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 0.36 0.33 0.88
53 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
54 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
55 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
56 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
57 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
58 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
59 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
60 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
61 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
62 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
63 INT105249 Cyb5b Positive_regulation of Localization of Prl 1 0.04 0 0.79
64 INT105250 Cyb5b Regulation of Localization of Gh1 1 0.00 0 0.79
65 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
66 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
67 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
68 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
69 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
70 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
71 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
72 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
73 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
74 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
75 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
76 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
77 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
78 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
79 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
80 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
81 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
82 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
83 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
84 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
85 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
86 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
87 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
88 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
89 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
90 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
91 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
92 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
93 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
94 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
95 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
96 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
97 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
98 INT108018 Binding of Slc37a4 and Clec4d 1 0.00 1.18 0.6
99 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
100 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
101 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
102 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
103 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
104 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
105 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
106 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
107 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57
108 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
109 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
110 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
111 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
112 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
113 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
114 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
115 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
116 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
117 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
118 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
119 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
120 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
121 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
122 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
123 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
124 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
125 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
126 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
127 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
128 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
129 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
130 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
131 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
132 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
133 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
134 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
135 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
136 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
137 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
138 INT65007 DAK Negative_regulation of CTSA 1 0.03 0.35 0.48
139 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
140 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
141 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
142 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
143 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
144 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
145 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
146 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
147 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
148 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45
149 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
150 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
151 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
152 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
153 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
154 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
155 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
156 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
157 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
158 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
159 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
160 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
161 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43
162 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
163 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
164 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
165 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
166 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
167 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
168 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
169 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
170 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
171 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
172 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
173 INT7636 RFC1 Negative_regulation of Localization of Oxt 1 0.14 0 0.39
174 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
175 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
176 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
177 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
178 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
179 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37
180 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
181 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
182 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
183 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
184 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
185 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
186 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
187 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
188 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
189 INT187219 Vip Negative_regulation of Gene_expression of Ccl3 1 0.32 0.65 0.35
190 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
191 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
192 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
193 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
194 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
195 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
196 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
197 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
198 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
199 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
200 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of catalytic activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of catalytic activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
2 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
3 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
4 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
5 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
6 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
7 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
8 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
9 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
10 INT1158 Regulation of Agt 106 0.61 29.4 30.29
11 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
12 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
13 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
14 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
15 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
16 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
17 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
18 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
19 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
20 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
21 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
22 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
23 INT2066 Localization of Agt 56 0.80 9.95 16.25
24 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
25 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
26 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
27 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
28 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
29 INT3962 Regulation of AGT 50 0.62 20.96 13.01
30 INT4199 Binding of Agt 76 0.48 21.06 12.66
31 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
32 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
33 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35
34 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
35 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
36 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
37 INT398 Localization of AGT 45 0.78 16.97 11.54
38 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
39 INT8065 Binding of AGT 54 0.48 20.54 10.85
40 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
41 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
42 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
43 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
44 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
45 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
46 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
47 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
48 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
49 INT82709 Negative_regulation of Slc37a4 17 0.34 3.41 8.6
50 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
51 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
52 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
53 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
54 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
55 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
56 INT97623 Negative_regulation of Adc 17 0.56 3.81 8.14
57 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
58 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
59 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
60 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
61 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
62 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
63 INT197493 Localization of Apoe 61 0.79 27.48 7.06
64 INT127691 Gene_expression of CXCL1 23 0.66 18.11 7.04
65 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
66 INT110104 Localization of Prkce 17 0.79 3.75 6.92
67 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
68 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
69 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
70 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
71 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
72 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
73 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
74 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
75 INT63042 Binding of Apoe 59 0.48 31.23 5.88
76 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
77 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
78 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
79 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
80 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
81 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
82 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
83 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
84 INT157802 Negative_regulation of Timp2 7 0.54 5.75 5.51
85 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
86 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
87 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
88 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
89 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
90 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92
91 INT97624 Positive_regulation of Adc 13 0.69 5.56 4.87
92 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
93 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69
94 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
95 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
96 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
97 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55
98 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
99 INT111068 Regulation of Psenen 6 0.35 4.17 4.33
100 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
101 INT55743 Gene_expression of Timp2 25 0.31 8.95 4.3
102 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
103 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
104 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
105 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
106 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
107 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
108 INT184288 Localization of HMGB1 20 0.61 14.5 3.84
109 INT151427 Gene_expression of ADC 31 0.55 21.86 3.81
110 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81
111 INT25709 Negative_regulation of Igf2 11 0.56 9.38 3.76
112 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
113 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
114 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
115 INT200385 Negative_regulation of ADC 19 0.18 16.56 3.6
116 INT228465 Positive_regulation of Timp2 4 0.64 6.29 3.54
117 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
118 INT109840 Localization of Prkce 5 0.74 3.01 3.45
119 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
120 INT181357 Negative_regulation of Ccl3 12 0.59 13.09 3.38
121 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
122 INT72141 Binding of Apoe 11 0.37 10.91 3.27
123 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
124 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
125 INT97710 Localization of Apoe 1 0.79 7.18 3.2
126 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
127 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
128 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
129 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
130 INT179338 Gene_expression of Timp2 7 0.55 5.75 3.13
131 INT27446 Negative_regulation of CTSA 11 0.57 5.58 3.08
132 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
133 INT105884 Binding of Bcl2 19 0.35 15.67 3
134 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
135 INT36886 Transcription of Myc 6 0.69 3.16 2.86
136 INT9335 Gene_expression of Igf2 18 0.72 12.76 2.78
137 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71
138 INT50080 Binding of APOE 38 0.45 29.61 2.67
139 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64
140 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
141 INT91899 Binding of Sod1 17 0.47 11.56 2.63
142 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
143 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
144 INT31989 Binding of SOD1 43 0.47 19.38 2.55
145 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
146 INT184272 Binding of HMGB1 14 0.37 8.78 2.49
147 INT169553 Positive_regulation of Slc37a4 9 0.13 2.94 2.49
148 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
149 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
150 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
151 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
152 INT163544 Binding of Psen1 40 0.36 15.28 2.42
153 INT200384 Regulation of ADC 12 0.25 5.46 2.41
154 INT99607 Transcription of NR4A2 2 0.68 1.61 2.41
155 INT9327 Localization of Igf2 8 0.80 5.07 2.36
156 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31
157 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
158 INT31118 Localization of Casp3 17 0.73 11.55 2.3
159 INT130230 Positive_regulation of Sod1 3 0.67 1.63 2.3
160 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29
161 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
162 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
163 INT51083 Gene_expression of Adc 14 0.53 8.24 2.25
164 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
165 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
166 INT120109 Negative_regulation of Timp2 8 0.33 3.28 2.23
167 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
168 INT57132 Positive_regulation of Igf2 9 0.50 5.15 2.22
169 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
170 INT68277 Positive_regulation of CXCL1 6 0.56 6.98 2.14
171 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
172 INT86460 Binding of Slc37a4 5 0.04 1.8 2.08
173 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
174 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
175 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
176 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
177 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
178 INT124052 Binding of Prkce 2 0.06 2.52 2.03
179 INT60723 Localization of Psen2 5 0.68 2.11 2.02
180 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
181 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
182 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
183 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
184 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
185 INT134097 Binding of CXCL1 1 0.17 1.35 1.88
186 INT69222 Positive_regulation of Sod1 15 0.61 8.19 1.87
187 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
188 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
189 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
190 INT145655 Transcription of Sod1 3 0.42 0.92 1.84
191 INT69221 Negative_regulation of Sod1 14 0.56 10.57 1.83
192 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81
193 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
194 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
195 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
196 INT127692 Positive_regulation of Gene_expression of CXCL1 8 0.56 6.26 1.71
197 INT81169 Localization of Nr4a2 1 0.68 0 1.71
198 INT3152 Transcription of Agt 7 0.72 5.09 1.68
199 INT99258 Regulation of Aph1a 3 0.25 2.79 1.68
200 INT215928 Binding of Timp2 1 0.23 0.79 1.66
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox