GO:0043089

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Name positive regulation of Cdc42 GTPase activity
Categary Process
Go Slim No
Go Link GO:0043089
Unique Molecular Interactions 70
Total Molecular Interactions 133
Total Single Events 726
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Cdc42 GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of Cdc42 GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
3 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
4 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
5 INT140934 Binding of Cd40 and Ean5 1 0.09 1.03 0.98
6 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
7 INT92998 Positive_regulation of SFTPA1 Positive_regulation of Localization of CD40 1 0.15 0.34 0.61
8 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
9 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55
10 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52
11 INT189846 Binding of Cd40 and Churc1 1 0.01 0.73 0.41
12 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
13 INT188696 Binding of Cd40 and Eae1 1 0.05 1.57 0.21
14 INT238001 Cxcl10 Positive_regulation of Gene_expression of Cd40 1 0.17 0.91 0.21
15 INT311987 Binding of Cd40 and Negative_regulation of Regulation of Hand1 1 0.28 0.27 0.21
16 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18
17 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18
18 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18
19 INT337180 CD40 Positive_regulation of Gene_expression of CD83 1 0.17 1.07 0.17
20 INT310257 Tlr4 Positive_regulation of Gene_expression of Cd40 1 0.13 0.06 0.15
21 INT188697 Il6 Positive_regulation of Cd40 1 0.05 0.18 0.14
22 INT47351 Binding of Ralbp1 and Ccl4 1 0.11 0.17 0.14
23 INT249598 Stat1 Positive_regulation of Gene_expression of Cd40 1 0.41 0.46 0.14
24 INT272776 CD40 Positive_regulation of Gene_expression of IGHG3 1 0.01 0.18 0.14
25 INT47352 Positive_regulation of Binding of Ralbp1 and Ccl4 1 0.14 0.17 0.14
26 INT324128 Binding of Cd4 and Cd40 2 0.29 0.3 0.13
27 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13
28 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13
29 INT331564 Binding of Apcs and Cd40 1 0.12 0.74 0.13
30 INT324082 CD40 Positive_regulation of MAPK9 1 0.21 0.64 0.13
31 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1
32 INT189848 IFN1@ Positive_regulation of Gene_expression of Cd40 1 0.69 0 0.09
33 INT249601 IFNA1 Negative_regulation of Gene_expression of Cd40 1 0.42 0.51 0.09
34 INT252344 Binding of Cd40 and Mthfd1 2 0.16 0.34 0.08
35 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08
36 INT231504 Binding of Tlr4 and Cd40 1 0.09 0.18 0.08
37 INT337166 PTGER2 Positive_regulation of Gene_expression of CD40 1 0.02 0.77 0.07
38 INT234381 Binding of CD40 and PPARA 1 0.19 1.39 0.07
39 INT220903 Regulation of Binding of Crp and Cd40 1 0.05 0.37 0.05
40 INT220906 Binding of Crp and Cd40 1 0.04 0.37 0.05
41 INT284559 Gopc Positive_regulation of Cd40 1 0.19 0.23 0.05
42 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05
43 INT325261 Ralbp1 Positive_regulation of Gene_expression of Il33 1 0.01 0 0.05
44 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04
45 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03
46 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
47 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03
48 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 0.17 0.74 0.03
49 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
50 INT252339 Binding of Cd40 and Positive_regulation of Mthfd1 1 0.04 0.19 0
51 INT316500 INO80B Positive_regulation of RALBP1 1 0.00 0.31 0
52 INT349016 Negative_regulation of Binding of Cd80 and Cd40 1 0.25 0 0
53 INT220901 Regulation of Binding of Saa1 and Cd40 1 0.04 0.36 0
54 INT170586 CD40 Negative_regulation of Positive_regulation of RELA 1 0.12 0.24 0
55 INT276390 Positive_regulation of CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0
56 INT276378 CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0
57 INT290160 Atp6v1e1 Positive_regulation of Cd40 1 0.24 0.5 0
58 INT252341 Cd40 Positive_regulation of Gene_expression of Cd80 1 0.12 0.1 0
59 INT248298 Binding of Cd40 and Rf 1 0.08 0 0
60 INT314970 Binding of Cd40 and Lbr 1 0.03 0.07 0
61 INT252334 Positive_regulation of Binding of Cd40 and Cd40lg 1 0.11 0.1 0
62 INT277864 Binding of ERBB2 and Ralbp1 1 0.28 0.57 0
63 INT284553 Adc Positive_regulation of Gene_expression of Cd40 1 0.18 0.35 0
64 INT288008 Binding of CD40 and LRRC23 1 0.02 0.45 0
65 INT220900 Binding of C4bp and Cd40 1 0.21 0.72 0
66 INT220908 Binding of Saa1 and Cd40 1 0.04 0.36 0
67 INT352086 Binding of CD40 and ADAM11 1 0.08 0.77 0
68 INT349017 Binding of Cd80 and Cd40 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Cdc42 GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of Cdc42 GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
2 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
3 INT133156 Binding of Cd40 77 0.48 45.92 13.77
4 INT93003 Binding of CD40 28 0.47 20.25 7.13
5 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51
6 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56
7 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
8 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
9 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
10 INT140932 Binding of Cd40 1 0.44 4.19 3.6
11 INT93915 Positive_regulation of Gene_expression of CD40 14 0.44 12.45 3.35
12 INT142606 Regulation of Gene_expression of Cd40 13 0.56 6.15 3.27
13 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1
14 INT140929 Gene_expression of Cd40 9 0.72 8.76 2.88
15 INT96151 Negative_regulation of Gene_expression of Cd40 20 0.58 6.06 2.58
16 INT248297 Negative_regulation of Cd40 14 0.58 8.96 2.34
17 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
18 INT93001 Localization of CD40 4 0.78 1.97 1.45
19 INT188691 Negative_regulation of Binding of Cd40 3 0.42 2.49 1.31
20 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
21 INT189836 Regulation of Cd40 10 0.40 3.02 1.1
22 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
23 INT140930 Positive_regulation of Gene_expression of Cd40 4 0.64 3.26 0.99
24 INT170603 Negative_regulation of Gene_expression of CD40 5 0.32 2.18 0.78
25 INT5211 Localization of Cd40 6 0.78 1.75 0.71
26 INT97130 Negative_regulation of CD40 5 0.35 1.96 0.63
27 INT269970 Positive_regulation of Positive_regulation of Cd40 2 0.50 1.79 0.57
28 INT188663 Regulation of Binding of Cd40 1 0.41 0.95 0.55
29 INT311966 Positive_regulation of Cd40 2 0.50 1.46 0.49
30 INT354384 Regulation of CCL19 1 0.23 1.89 0.47
31 INT238502 Regulation of CD40 6 0.28 3.7 0.44
32 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43
33 INT216992 Regulation of Binding of CD40 1 0.13 0.06 0.41
34 INT188680 Positive_regulation of Binding of Cd40 1 0.46 1.33 0.32
35 INT176333 Transcription of Cd40 1 0.52 0.8 0.28
36 INT5213 Regulation of Localization of Cd40 1 0.26 0 0.27
37 INT105135 Positive_regulation of Ralbp1 1 0.60 1.49 0.26
38 INT105134 Regulation of Ralbp1 1 0.23 1.5 0.26
39 INT217002 Positive_regulation of Localization of CD40 1 0.14 0 0.26
40 INT305840 Positive_regulation of Gene_expression of Ccr7 1 0.27 0.25 0.24
41 INT311985 Regulation of Positive_regulation of Cd40 1 0.45 0.64 0.24
42 INT220167 Localization of Ccr7 1 0.31 0.39 0.18
43 INT252316 Regulation of Regulation of Cd40 2 0.24 0.71 0.15
44 INT238504 Positive_regulation of Positive_regulation of CD40 2 0.36 3.03 0.15
45 INT316515 Positive_regulation of RALBP1 28 0.25 10.37 0.14
46 INT234680 Localization of Cd40 1 0.18 0.16 0.14
47 INT188260 Gene_expression of Ralbp1 1 0.02 0.53 0.14
48 INT47350 Binding of Ralbp1 1 0.10 0.17 0.14
49 INT170592 Regulation of Gene_expression of CD40 4 0.17 0 0.11
50 INT316511 Gene_expression of RALBP1 5 0.28 5.24 0.1
51 INT105132 Localization of Ralbp1 2 0.60 0.52 0.09
52 INT105133 Positive_regulation of Localization of Ralbp1 1 0.40 0.47 0.09
53 INT288014 Negative_regulation of Positive_regulation of CD40 1 0.17 0.63 0.09
54 INT311981 Regulation of Protein_catabolism of Cd40 1 0.45 0.31 0.07
55 INT311983 Protein_catabolism of Cd40 1 0.88 0.31 0.07
56 INT275162 Negative_regulation of Gene_expression of Cd40 1 0.14 1.23 0.06
57 INT352112 Transcription of CCL19 1 0.38 1.37 0.06
58 INT352100 Positive_regulation of Transcription of CCL19 1 0.37 1.38 0.06
59 INT211878 Transcription of CD40 2 0.35 2.01 0.03
60 INT326159 Positive_regulation of Gene_expression of RALBP1 1 0.25 1.58 0.03
61 INT352095 Regulation of Gene_expression of CCL19 1 0.21 0.68 0.03
62 INT337233 Positive_regulation of Binding of CD40 1 0.26 0.6 0.03
63 INT316514 Regulation of Positive_regulation of RALBP1 1 0.07 0.38 0
64 INT352113 Positive_regulation of Positive_regulation of CCL19 1 0.27 1.06 0
65 INT316512 Negative_regulation of Gene_expression of RALBP1 1 0.07 0.23 0
66 INT166967 Negative_regulation of Ccr7 1 0.09 0 0
67 INT316509 Positive_regulation of Positive_regulation of RALBP1 1 0.08 0.65 0
68 INT352098 Negative_regulation of Gene_expression of CCL19 1 0.23 1.48 0
69 INT284542 Negative_regulation of Positive_regulation of Cd40 1 0.27 0.28 0
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