GO:0043113

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Name receptor clustering
Categary Process
Go Slim No
Go Link GO:0043113
Unique Molecular Interactions 380
Total Molecular Interactions 659
Total Single Events 2772
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor clustering. They are ordered first by their pain relevance and then by number of times they were reported for receptor clustering. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
6 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
7 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
8 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
9 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
10 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
11 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
12 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
13 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
14 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
15 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
16 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
17 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
18 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
19 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
20 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
21 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
22 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
23 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
24 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
25 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
26 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
27 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
28 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
29 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
30 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
31 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
32 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
33 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
34 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
35 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
36 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
37 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
38 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
39 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
40 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
41 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
42 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
43 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
44 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
45 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
46 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
47 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
48 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
49 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
50 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
51 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
52 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
53 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
54 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
55 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
56 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
57 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
58 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
59 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
60 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
61 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
62 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
63 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
64 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
65 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
66 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
67 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
68 INT232622 Magi2 Regulation of Cysltr1 1 0.01 0.58 0.67
69 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
70 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
71 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
72 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
73 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64
74 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64
75 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
76 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63
77 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
78 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
79 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
80 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59
81 INT296486 Binding of Pick1 and GRIP1 1 0.03 0.32 0.59
82 INT296475 Binding of Pick1 and Myo18a 2 0.01 1.63 0.57
83 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
84 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
85 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
86 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
87 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
88 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
89 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
90 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
91 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
92 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
93 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
94 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
95 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
96 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
97 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
98 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
99 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
100 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
101 INT354704 Binding of MAP3K1 and Pick1 1 0.00 0.76 0.41
102 INT274781 Agrn Positive_regulation of Chrna2 1 0.08 0.18 0.41
103 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
104 INT354719 Binding of ASIC1 and Pick1 1 0.40 2.34 0.4
105 INT106114 Binding of ASIC2 and Pick1 1 0.14 0.1 0.4
106 INT106116 Binding of ASIC1 and Pick1 1 0.04 0.1 0.4
107 INT299181 Cysltr1 Regulation of Musk 1 0.08 1.21 0.4
108 INT296296 Binding of Grin2b and Kcnip3 1 0.24 0 0.4
109 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
110 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
111 INT106115 Pick1 Positive_regulation of Phosphorylation of ASIC2 1 0.13 0.07 0.39
112 INT106117 Pick1 Positive_regulation of ASIC2 1 0.14 0.09 0.39
113 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
114 INT296476 Binding of Pick1 and Rbm39 1 0.00 0.57 0.37
115 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
116 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
117 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
118 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
119 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
120 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
121 INT354697 Positive_regulation of Binding of Gria2 and Pick1 1 0.08 0.73 0.33
122 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
123 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
124 INT251148 Negative_regulation of Binding of Grin2a and Dlg2 1 0.37 0.45 0.32
125 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
126 INT296447 Pick1 Regulation of Gria2 1 0.16 0.49 0.3
127 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
128 INT334834 Binding of Pick1 and Camkk1 1 0.00 0.5 0.3
129 INT263749 Binding of Grin2b and Neto1 1 0.38 0 0.3
130 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
131 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
132 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
133 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
134 INT274946 Binding of Pick1 and Insrr 1 0.00 0 0.28
135 INT274944 Binding of Dlg4 and Pick1 1 0.04 0 0.28
136 INT274934 Binding of Pick1 and Grip1 1 0.05 0 0.27
137 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
138 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
139 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
140 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
141 INT197232 Binding of Grik5 and Kars 1 0.17 0.1 0.25
142 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
143 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
144 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
145 INT208123 Hpcal1 Regulation of Grin2b 1 0.10 0 0.21
146 INT354710 Pick1 Regulation of ASIC1 1 0.37 1.12 0.21
147 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
148 INT354721 Pick1 Regulation of Gene_expression of ASIC1 1 0.37 1.1 0.2
149 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
150 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
151 INT354700 Binding of Pick1 and Bfar 1 0.05 0.9 0.19
152 INT111380 Musk Negative_regulation of Phka2 1 0.03 0.92 0.19
153 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
154 INT355305 Use1 Positive_regulation of Gene_expression of Clec2i 1 0.01 3 0.18
155 INT355304 Use1 Positive_regulation of Clec2i 1 0.01 3 0.18
156 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17
157 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
158 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
159 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
160 INT244045 Binding of Arhgef9 and Gphn 1 0.02 0.2 0.15
161 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
162 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
163 INT273233 Negative_regulation of Cdk5 Negative_regulation of Positive_regulation of Ltp 1 0.20 0.39 0.13
164 INT273239 Cdk5 Positive_regulation of Positive_regulation of GRIN1 1 0.51 0.37 0.12
165 INT312631 Binding of Musk and Agrn 1 0.40 0.63 0.12
166 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
167 INT354712 Pick1 Positive_regulation of Gene_expression of ASIC1 1 0.39 0.74 0.11
168 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
169 INT263729 Grin2b Positive_regulation of Gene_expression of Car1 1 0.20 0 0.1
170 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
171 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
172 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
173 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
174 INT221954 Binding of CDK5 and CDK5R2 1 0.02 0.36 0.09
175 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
176 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
177 INT354713 Pick1 Regulation of Localization of ASIC1 1 0.22 0.48 0.08
178 INT20957 Binding of Pak1 and Pak2 1 0.27 0.65 0.08
179 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
180 INT263755 Grin1 Regulation of Localization of Grin2b 1 0.27 0.17 0.07
181 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
182 INT263741 Grin2b Regulation of Localization of Dlg4 1 0.17 0.17 0.07
183 INT335890 Binding of Dkk1 and Lrp4 1 0.37 0.64 0.07
184 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07
185 INT263728 Grin2b Regulation of Localization of Grin1 1 0.27 0.17 0.07
186 INT263723 Grin2b Regulation of Localization of Gria2 1 0.18 0.17 0.07
187 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
188 INT312645 Binding of DNAJA3 and Musk 1 0.08 0.96 0.07
189 INT263762 Grin2a Regulation of Localization of Grin2b 1 0.26 0.17 0.07
190 INT263722 Dlg4 Regulation of Localization of Grin2b 1 0.15 0.17 0.07
191 INT263739 Grin2b Regulation of Localization of Vamp2 1 0.24 0.17 0.07
192 INT263768 Grin2b Regulation of Localization of Grin2a 1 0.26 0.17 0.07
193 INT312636 Negative_regulation of Binding of Musk and Lrp4 1 0.21 0.32 0.06
194 INT263767 Binding of Camk2a and Grin2b 1 0.18 0 0.06
195 INT312639 Binding of Musk and Lrp4 1 0.23 0.91 0.06
196 INT312632 Binding of Agrn and Lrp4 1 0.17 0.32 0.06
197 INT312647 Binding of Agrn and SYCP3 1 0.39 0.32 0.06
198 INT312627 Negative_regulation of Binding of Musk and Agrn 1 0.46 0.32 0.06
199 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
200 INT231300 Positive_regulation of Grin2b Positive_regulation of Prnp 1 0.39 0.16 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor clustering. They are ordered first by their pain relevance and then by number of times they were reported in receptor clustering. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
3 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
4 INT221172 Binding of Flna 32 0.42 1.37 51.59
5 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
6 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
7 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
8 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
9 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
10 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
11 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
12 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
13 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
14 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
15 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
16 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
17 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
18 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
19 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
20 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
21 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
22 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
23 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
24 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
25 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
26 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
27 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
28 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
29 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
30 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
31 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
32 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
33 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
34 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
35 INT112099 Negative_regulation of Dlg2 2 0.40 6.17 8.16
36 INT112101 Gene_expression of Dlg2 9 0.73 5.06 6.5
37 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
38 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
39 INT251134 Binding of Dlg2 6 0.31 4.26 5.99
40 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
41 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
42 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
43 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
44 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
45 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
46 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
47 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
48 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
49 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
50 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
51 INT39948 Binding of FLNA 45 0.42 58.05 4.27
52 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
53 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
54 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
55 INT221168 Localization of Flna 1 0.58 0.05 4.05
56 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
57 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
58 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
59 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
60 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
61 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
62 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
63 INT154198 Binding of Pick1 9 0.48 6.91 3.16
64 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
65 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
66 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
67 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
68 INT166378 Positive_regulation of Gene_expression of Pick1 6 0.61 1.94 2.77
69 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
70 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
71 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
72 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
73 INT46646 Localization of FLNA 19 0.73 18.83 2.53
74 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
75 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
76 INT251126 Regulation of Dlg2 1 0.40 1.56 2.46
77 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
78 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
79 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
80 INT251127 Regulation of Gene_expression of Dlg2 1 0.35 1.49 2.23
81 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
82 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
83 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
84 INT221179 Regulation of Flna 1 0.24 0.13 2.04
85 INT251128 Regulation of Negative_regulation of Dlg2 1 0.24 1.97 2.01
86 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
87 INT166380 Positive_regulation of Pick1 5 0.44 1.26 1.95
88 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
89 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
90 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
91 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
92 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
93 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
94 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
95 INT124667 Negative_regulation of Grik2 4 0.41 2.06 1.7
96 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
97 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
98 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
99 INT124669 Gene_expression of Grik2 6 0.75 1.66 1.47
100 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
101 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
102 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
103 INT296265 Regulation of Phosphorylation of Grin2b 2 0.44 1.06 1.4
104 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
105 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
106 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
107 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
108 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
109 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
110 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
111 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
112 INT131970 Regulation of Grik2 3 0.26 0.65 1.15
113 INT113607 Positive_regulation of Pick1 1 0.48 0.82 1.13
114 INT143091 Positive_regulation of Negative_regulation of Grin2b 2 0.44 0.9 1.09
115 INT291961 Negative_regulation of Regulation of Grin2b 1 0.30 1.65 1.09
116 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
117 INT116659 Regulation of Pick1 3 0.41 0.86 1.01
118 INT166377 Gene_expression of Pick1 3 0.68 2.9 0.97
119 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
120 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
121 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
122 INT168534 Gene_expression of Grik5 3 0.38 0.64 0.9
123 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
124 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
125 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
126 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
127 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85
128 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
129 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85
130 INT287954 Gene_expression of DVL1 8 0.24 2.48 0.83
131 INT167424 Positive_regulation of Pak1 1 0.14 1.43 0.83
132 INT143092 Negative_regulation of Negative_regulation of Grin2b 1 0.27 0.33 0.83
133 INT131967 Transcription of Grik2 2 0.67 0.73 0.82
134 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
135 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
136 INT131966 Regulation of Regulation of Grik2 1 0.26 0.45 0.75
137 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74
138 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
139 INT106106 Gene_expression of Pick1 3 0.70 0.66 0.68
140 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
141 INT196790 Localization of Cdk5 6 0.74 2.6 0.67
142 INT141227 Phosphorylation of CACNA1A 1 0.55 0.78 0.66
143 INT139895 Positive_regulation of Gene_expression of GRIN2B 2 0.49 0.9 0.65
144 INT147397 Negative_regulation of Binding of Grin2b 1 0.16 0.87 0.63
145 INT122116 Negative_regulation of Transcription of Grin2b 1 0.43 0.34 0.62
146 INT271625 Protein_catabolism of Grin2b 1 0.38 0.26 0.57
147 INT127557 Positive_regulation of Phosphorylation of Cdk5 2 0.50 0.43 0.56
148 INT296255 Negative_regulation of Localization of Grin2b 1 0.30 0.16 0.56
149 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55
150 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54
151 INT156378 Regulation of Binding of Grin2b 1 0.28 0.17 0.52
152 INT163895 Positive_regulation of Phosphorylation of GRIN2B 1 0.09 0.99 0.48
153 INT271632 Negative_regulation of Regulation of Grin2b 2 0.28 1.06 0.47
154 INT250065 Positive_regulation of Localization of Grin2b 1 0.45 0 0.47
155 INT256033 Negative_regulation of Musk 2 0.42 0.92 0.44
156 INT166384 Positive_regulation of Positive_regulation of Pick1 1 0.15 0.19 0.44
157 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
158 INT106108 Phosphorylation of Pick1 1 0.54 0.07 0.39
159 INT221178 Positive_regulation of Gene_expression of Flna 1 0.39 0 0.38
160 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
161 INT273218 Negative_regulation of Negative_regulation of Cdk5 1 0.42 3.06 0.37
162 INT271630 Negative_regulation of Localization of Grin2b 1 0.25 0 0.37
163 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36
164 INT168536 Localization of Grik5 1 0.07 0.09 0.34
165 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
166 INT250062 Positive_regulation of Transcription of Grin2b 1 0.39 0.47 0.34
167 INT168539 Regulation of Gene_expression of Grik5 1 0.02 0.09 0.34
168 INT155753 Regulation of Gene_expression of CACNA1A 1 0.27 0.66 0.32
169 INT354672 Positive_regulation of Binding of Pick1 1 0.61 1.32 0.31
170 INT287931 Positive_regulation of Gene_expression of DVL1 2 0.09 0.08 0.29
171 INT163897 Negative_regulation of Phosphorylation of GRIN2B 1 0.08 0.39 0.28
172 INT271629 Positive_regulation of Protein_catabolism of Grin2b 1 0.27 0.13 0.28
173 INT326820 Negative_regulation of Positive_regulation of Cdk5 1 0.36 1.27 0.28
174 INT298972 Transcription of Cdk5 1 0.15 1.63 0.28
175 INT319268 Positive_regulation of Dlg2 1 0.16 0.42 0.28
176 INT313623 Regulation of Localization of Grin2b 1 0.32 0 0.24
177 INT164788 Regulation of Gene_expression of Cdk5 1 0.27 0.31 0.24
178 INT273223 Positive_regulation of Protein_catabolism of Grin2b 1 0.40 0.73 0.23
179 INT208117 Positive_regulation of Binding of Grin2b 1 0.46 0 0.23
180 INT335874 Regulation of Lrp4 1 0.18 0 0.23
181 INT238079 Gene_expression of Agrn 1 0.14 0.16 0.22
182 INT273229 Protein_catabolism of Grin2b 1 0.57 1.29 0.22
183 INT312604 Gene_expression of Lrp4 2 0.71 1.48 0.21
184 INT238072 Protein_catabolism of Agrn 1 0.14 0.24 0.2
185 INT238084 Localization of Agrn 1 0.16 0.24 0.2
186 INT219375 Localization of CDK5 4 0.52 2.8 0.19
187 INT221974 Phosphorylation of CDK5 1 0.56 0.99 0.19
188 INT299175 Regulation of Musk 1 0.18 0.5 0.19
189 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
190 INT355263 Gene_expression of Clec2i 1 0.05 2.95 0.18
191 INT273226 Negative_regulation of Gene_expression of Cdk5 2 0.42 0.79 0.17
192 INT289128 Negative_regulation of Gene_expression of DVL1 1 0.07 0.31 0.17
193 INT289117 Negative_regulation of DVL1 1 0.07 0.31 0.17
194 INT270959 Binding of Pick1 2 0.35 0.2 0.16
195 INT157582 Regulation of Phosphorylation of Cdk5 1 0.26 0.25 0.16
196 INT221972 Regulation of CDK5 1 0.42 1.87 0.16
197 INT287922 Phosphorylation of DVL1 4 0.20 1.21 0.12
198 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
199 INT354674 Negative_regulation of Pick1 1 0.37 0.48 0.12
200 INT326822 Negative_regulation of Phosphorylation of Cdk5 1 0.36 0.43 0.12
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