GO:0043114

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Name regulation of vascular permeability
Categary Process
Go Slim No
Go Link GO:0043114
Unique Molecular Interactions 69
Total Molecular Interactions 78
Total Single Events 679
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of vascular permeability. They are ordered first by their pain relevance and then by number of times they were reported for regulation of vascular permeability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
2 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16
3 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02
4 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
5 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
6 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84
7 INT166902 NPPB Positive_regulation of TRPA1 1 0.78 0.76 0.77
8 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
9 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
10 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
11 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
12 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
13 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
14 INT332701 Binding of BDKRB1 and BDKRB2 1 0.01 0.5 0.39
15 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
16 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
17 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34
18 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
19 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
20 INT166901 NPPB Positive_regulation of Gene_expression of TRPA1 1 0.68 0.33 0.3
21 INT118853 Negative_regulation of SRC Negative_regulation of Positive_regulation of STAT3 1 0.41 0.08 0.28
22 INT118855 Binding of SRC and GNA14 1 0.01 0.13 0.27
23 INT100680 IL4 Positive_regulation of SRC 1 0.42 0.66 0.26
24 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
25 INT118858 PRKCA Regulation of Phosphorylation of SRC 1 0.10 0.15 0.24
26 INT170158 NPPA Positive_regulation of Gene_expression of NPPB 1 0.13 0.91 0.23
27 INT118850 GNA14 Positive_regulation of Phosphorylation of SRC 1 0.02 0.15 0.23
28 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
29 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
30 INT269333 Binding of BDKRB2 and NOS3 1 0.02 0 0.17
31 INT251435 Gnat3 Positive_regulation of NPR1 1 0.22 0.2 0.15
32 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11
33 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
34 INT299291 Negative_regulation of PTPN3 Positive_regulation of Phosphorylation of SRC 1 0.07 0.12 0.07
35 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05
36 INT281906 BDKRB2 Positive_regulation of ANG 1 0.11 0.51 0.05
37 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05
38 INT238113 SRC Regulation of Phosphorylation of STAT3 1 0.46 0 0.04
39 INT316217 BDKRB1 Positive_regulation of BDKRB2 1 0.09 0.71 0.03
40 INT316218 GOPC Positive_regulation of BDKRB2 1 0.08 0.71 0.03
41 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03
42 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
43 INT338198 SRC Positive_regulation of STAT3 1 0.11 0.34 0
44 INT299303 SRC Regulation of Phosphorylation of VEGFA 1 0.12 0.05 0
45 INT285579 Binding of S100A8 and SRC 1 0.05 0.2 0
46 INT299305 VEGFA Positive_regulation of Positive_regulation of SRC 1 0.22 0 0
47 INT299300 SRC Positive_regulation of Phosphorylation of AKT1 1 0.24 0 0
48 INT279289 TXK Regulation of SRC 1 0.04 0.68 0
49 INT299296 SRC Regulation of RPTOR 1 0.32 0 0
50 INT114712 SRC Positive_regulation of Gene_expression of IGF1R 1 0.63 0.51 0
51 INT338189 SRC Positive_regulation of HGFAC 1 0.00 0.4 0
52 INT299285 SRC Regulation of Gene_expression of QPCT 1 0.03 0 0
53 INT256210 NPPB Regulation of PVR 1 0.24 1.14 0
54 INT302174 Positive_regulation of SRC Positive_regulation of Phosphorylation of STAT3 1 0.11 1.01 0
55 INT302142 PTGER3 Positive_regulation of SRC 1 0.09 1.07 0
56 INT299308 SRC Regulation of PI3 1 0.20 0 0
57 INT299298 SRC Negative_regulation of PI3 1 0.19 0 0
58 INT338195 Binding of SRC and FIBP 1 0.00 0.31 0
59 INT309906 Binding of EGF and SRC 1 0.11 0.64 0
60 INT114713 Binding of IGF1R and SRC 1 0.33 0.6 0
61 INT340928 Negative_regulation of SRC Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
62 INT299294 SRC Regulation of VEGFA 1 0.20 0 0
63 INT238120 SRC Positive_regulation of Positive_regulation of STAT3 1 0.71 0 0
64 INT238114 Binding of CSK and SRC 1 0.07 0 0
65 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
66 INT338196 Binding of SRC and CDCP1 1 0.00 0.31 0
67 INT198019 NPY6R Negative_regulation of Gene_expression of SRC 1 0.06 1.75 0
68 INT256211 NPPB Regulation of PDAP1 1 0.28 1.14 0
69 INT114711 SRC Positive_regulation of Gene_expression of INSRR 1 0.01 0.51 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of vascular permeability. They are ordered first by their pain relevance and then by number of times they were reported in regulation of vascular permeability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04
2 INT66718 Positive_regulation of BDKRB2 21 0.64 9.89 11.6
3 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81
4 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
5 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54
6 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
7 INT83095 Regulation of Gene_expression of BDKRB2 2 0.59 4.06 5.39
8 INT48277 Regulation of BDKRB2 9 0.59 2.69 5.05
9 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
10 INT159472 Localization of NPPB 32 0.79 33.67 3.59
11 INT53347 Localization of BDKRB2 5 0.75 4.96 3.39
12 INT66720 Negative_regulation of BDKRB2 5 0.57 1.92 3.11
13 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
14 INT53348 Binding of BDKRB2 7 0.37 2.85 3
15 INT26205 Positive_regulation of Positive_regulation of NPR1 3 0.24 1.57 2.52
16 INT11065 Gene_expression of NPR1 6 0.55 3.41 2.32
17 INT120752 Positive_regulation of Gene_expression of NPPB 17 0.67 16.4 2.21
18 INT84264 Regulation of NPPB 22 0.61 21.18 1.94
19 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
20 INT98464 Positive_regulation of Positive_regulation of SRC 10 0.67 5.71 1.86
21 INT11098 Regulation of NPR1 5 0.37 1.39 1.74
22 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7
23 INT114715 Binding of SRC 8 0.36 4.26 1.32
24 INT120406 Positive_regulation of Positive_regulation of BDKRB2 2 0.27 1.48 1.28
25 INT11099 Localization of NPR1 5 0.67 1.49 1.21
26 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15
27 INT133846 Binding of NPPB 14 0.42 11.52 0.98
28 INT11100 Positive_regulation of Gene_expression of NPR1 2 0.37 1.49 0.98
29 INT23921 Negative_regulation of NPPB 13 0.58 16.19 0.9
30 INT11066 Negative_regulation of NPR1 5 0.27 0.89 0.88
31 INT32513 Regulation of Localization of NPR1 3 0.36 0.84 0.81
32 INT118004 Positive_regulation of Gene_expression of SRC 13 0.49 11.05 0.8
33 INT290271 Negative_regulation of Binding of BDKRB2 1 0.37 0.99 0.76
34 INT70530 Binding of NPR1 3 0.17 0.71 0.65
35 INT254132 Positive_regulation of Localization of NPPB 2 0.40 2.9 0.58
36 INT70532 Regulation of Regulation of NPR1 1 0.12 0.31 0.49
37 INT82608 Positive_regulation of Phosphorylation of SRC 3 0.49 1.28 0.48
38 INT166903 Negative_regulation of Gene_expression of NPPB 5 0.43 4.18 0.41
39 INT70531 Negative_regulation of Negative_regulation of NPR1 1 0.19 0.24 0.37
40 INT254367 Transcription of TEK 1 0.14 1.08 0.36
41 INT242293 Positive_regulation of Positive_regulation of NPPB 5 0.56 2.92 0.33
42 INT138051 Negative_regulation of Positive_regulation of SRC 3 0.57 0.84 0.33
43 INT32566 Positive_regulation of Localization of NPR1 1 0.58 0.17 0.33
44 INT181921 Binding of TEK 2 0.09 1.88 0.32
45 INT254372 Negative_regulation of TEK 1 0.12 1.05 0.31
46 INT159473 Regulation of Localization of NPPB 2 0.61 1 0.25
47 INT164162 Negative_regulation of Phosphorylation of SRC 3 0.29 2.12 0.21
48 INT271363 Positive_regulation of Regulation of NPPB 1 0.15 0.97 0.21
49 INT277030 Negative_regulation of Binding of NPPB 1 0.26 1.29 0.21
50 INT316230 Negative_regulation of Localization of BDKRB2 1 0.21 0.92 0.21
51 INT181788 Positive_regulation of Gene_expression of TEK 1 0.27 1.26 0.2
52 INT235725 Regulation of SRC 7 0.44 4.71 0.19
53 INT142561 Phosphorylation of NPPB 3 0.66 1.65 0.18
54 INT8094 Positive_regulation of Gene_expression of BDKRB2 1 0.12 1.02 0.15
55 INT226281 Regulation of TEK 1 0.60 1.33 0.11
56 INT299357 Localization of SRC 1 0.51 0 0.09
57 INT316232 Positive_regulation of Transcription of BDKRB2 1 0.23 0.7 0.09
58 INT316235 Transcription of BDKRB2 1 0.26 0.7 0.09
59 INT238187 Regulation of Positive_regulation of SRC 2 0.26 1.37 0.05
60 INT159886 Regulation of Gene_expression of NPPB 3 0.44 0.9 0.04
61 INT242291 Protein_catabolism of NPPB 2 0.57 1.79 0.04
62 INT254131 Negative_regulation of Localization of NPPB 1 0.37 0.72 0.04
63 INT238193 Regulation of Gene_expression of SRC 1 0.44 0 0.03
64 INT218765 Regulation of Localization of TEK 1 0.02 0.87 0
65 INT284146 Transcription of NPPB 1 0.06 0.27 0
66 INT218764 Localization of TEK 1 0.04 0.87 0
67 INT296884 Negative_regulation of Negative_regulation of NPPB 1 0.01 1.37 0
68 INT159885 Regulation of Regulation of NPPB 1 0.44 0 0
69 INT238185 Regulation of Binding of SRC 1 0.44 0.06 0
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