GO:0043117

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Name positive regulation of vascular permeability
Categary Process
Go Slim No
Go Link GO:0043117
Unique Molecular Interactions 1227
Total Molecular Interactions 1940
Total Single Events 16049
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of vascular permeability. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of vascular permeability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
2 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
3 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
4 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
5 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
6 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
7 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
8 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
9 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
10 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
11 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
12 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
13 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
14 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
15 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
16 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
17 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
18 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
19 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
20 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
21 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
22 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
23 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
24 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
25 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
26 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
27 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
28 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
29 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
30 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
31 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
32 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
33 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
34 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
35 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
36 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
37 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
38 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
39 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
40 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
41 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
42 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
43 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
44 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
45 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
46 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
47 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
48 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
49 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
50 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
51 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79
52 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
53 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77
54 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
55 INT95458 Nka1 Positive_regulation of Positive_regulation of Tacr1 1 0.52 0.16 0.77
56 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77
57 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
58 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
59 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
60 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
61 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
62 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
63 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
64 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
65 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
66 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
67 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
68 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
69 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
70 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
71 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
72 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
73 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
74 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65
75 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
76 INT189020 Tacr1 Positive_regulation of Pla2g1b 1 0.14 0.13 0.65
77 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64
78 INT124904 Binding of Tacr1 and Adarb1 2 0.01 0.5 0.63
79 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
80 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
81 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
82 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
83 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
84 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
85 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
86 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
87 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
88 INT167859 Tac1 Regulation of Gene_expression of Tacr1 1 0.09 0 0.6
89 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
90 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
91 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
92 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58
93 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
94 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
95 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
96 INT176370 IL18BP Negative_regulation of IL18 1 0.15 0.76 0.56
97 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55
98 INT69898 Binding of Olfr19 and Tacr1 1 0.00 0.1 0.55
99 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55
100 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
101 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54
102 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52
103 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
104 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
105 INT15273 Calca Regulation of Tacr1 1 0.22 0 0.5
106 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
107 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
108 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
109 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
110 INT157003 Gal Regulation of Localization of Tacr1 1 0.01 0.1 0.49
111 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
112 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
113 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
114 INT130312 Ccl4 Negative_regulation of Abcc3 1 0.33 0.28 0.48
115 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
116 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
117 INT130310 Ccl4 Positive_regulation of Abcc2 1 0.44 0.28 0.47
118 INT130311 Ccl4 Positive_regulation of Abcc1 1 0.47 0.28 0.47
119 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
120 INT148466 Ccl4 Positive_regulation of Hmox1 1 0.28 0.06 0.47
121 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
122 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
123 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
124 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
125 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
126 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45
127 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
128 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
129 INT354395 TNFSF12 Regulation of Gene_expression of IL18 1 0.47 0.79 0.45
130 INT127395 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Tacr1 1 0.07 0.71 0.45
131 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
132 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
133 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
134 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
135 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
136 INT98726 Binding of Msr1 and Tacr2 1 0.00 0.06 0.42
137 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
138 INT172136 IL18 Positive_regulation of Gene_expression of IFN1@ 1 0.09 0.63 0.42
139 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42
140 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42
141 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
142 INT178823 TNF Regulation of Il18 1 0.18 3.28 0.41
143 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
144 INT151633 Binding of Npy and Tacr1 1 0.16 0.39 0.4
145 INT22921 Ccl4 Positive_regulation of Gpt 1 0.00 0.24 0.39
146 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 0.10 0.84 0.39
147 INT141016 Il18 Positive_regulation of Gene_expression of Ifng 1 0.39 0.27 0.39
148 INT22920 Negative_regulation of Ccl4 Positive_regulation of Gpt 1 0.00 0.24 0.39
149 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
150 INT182054 Il18 Positive_regulation of LOH19CR1 1 0.55 0.74 0.38
151 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
152 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38
153 INT182052 Il18 Positive_regulation of Col7a1 1 0.03 0.74 0.38
154 INT182051 Il18 Positive_regulation of Il1 1 0.18 0.77 0.38
155 INT148465 Positive_regulation of Ccl4 Positive_regulation of Gclc 1 0.32 0.06 0.38
156 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37
157 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
158 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
159 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
160 INT148467 Ccl4 Positive_regulation of Gclc 1 0.32 0.05 0.37
161 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
162 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
163 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
164 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
165 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
166 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
167 INT176373 IL18 Regulation of FASLG 1 0.41 0.4 0.35
168 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
169 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
170 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
171 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
172 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
173 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
174 INT39971 Ccl4 Positive_regulation of Lpolv 1 0.15 0.32 0.33
175 INT207408 Il6 Positive_regulation of Gene_expression of Tacr1 1 0.08 0.56 0.33
176 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33
177 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
178 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
179 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33
180 INT98013 Il18 Positive_regulation of Gene_expression of IFNG 1 0.66 0.44 0.32
181 INT176362 Binding of IL18 and IL18BP 1 0.12 0.49 0.32
182 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
183 INT207409 Ptger2 Positive_regulation of Gene_expression of Tacr1 1 0.04 0.56 0.32
184 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31
185 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
186 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3
187 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
188 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
189 INT182053 Il18 Positive_regulation of TNF 1 0.06 0.63 0.29
190 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
191 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
192 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
193 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
194 INT75108 Binding of Tac2 and Tacr1 1 0.18 0.1 0.29
195 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
196 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
197 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
198 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
199 INT176372 Positive_regulation of IL18 Positive_regulation of IFNA1 1 0.16 0.36 0.28
200 INT98816 Crhr2 Positive_regulation of Negative_regulation of Ucn 1 0.33 0.09 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of vascular permeability. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of vascular permeability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
3 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
4 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
5 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
6 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
7 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
8 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
9 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
10 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
11 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
12 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
13 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
14 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
15 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
16 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
17 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
18 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
19 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
20 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
21 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
22 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
23 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48
24 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
25 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
26 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
27 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
28 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3
29 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
30 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
31 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
32 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
33 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
34 INT155808 Gene_expression of Ccl4 24 0.65 21.36 9.18
35 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
36 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
37 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
38 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
39 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
40 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
41 INT91721 Binding of IL18 21 0.48 21.17 6.56
42 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
43 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
44 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01
45 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
46 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
47 INT124705 Binding of Il18 29 0.47 19.02 5.59
48 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
49 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
50 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
51 INT188852 Gene_expression of Pde2a 13 0.19 6.44 5.35
52 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
53 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
54 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73
55 INT104549 Localization of Il18 16 0.78 13.01 4.64
56 INT165891 Transcription of Il18 5 0.69 7.63 4.37
57 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
58 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
59 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
60 INT35175 Localization of IL18 18 0.80 12.96 3.83
61 INT141015 Regulation of Il18 14 0.59 6.3 3.73
62 INT14936 Negative_regulation of Binding of Tacr1 4 0.58 0.75 3.67
63 INT148151 Regulation of Il18 7 0.28 5.4 3.5
64 INT56601 Positive_regulation of Ccl4 9 0.47 6.27 3.28
65 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
66 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
67 INT75815 Positive_regulation of PDE2A 10 0.40 5.1 3.15
68 INT8712 Regulation of Tacr2 5 0.45 0.53 3.02
69 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
70 INT176383 Negative_regulation of Binding of IL18 1 0.35 5.91 2.91
71 INT107950 Regulation of Gene_expression of Tacr1 6 0.61 1.13 2.84
72 INT65126 Transcription of Tacr1 5 0.63 3.44 2.77
73 INT30172 Positive_regulation of Pde2a 3 0.39 0.55 2.77
74 INT139562 Transcription of IL18 10 0.68 6.14 2.73
75 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73
76 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
77 INT222289 Localization of Il18 4 0.30 3.24 2.58
78 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
79 INT122367 Positive_regulation of Positive_regulation of Tacr1 5 0.46 1.47 2.4
80 INT165892 Positive_regulation of Transcription of Il18 3 0.66 3.72 2.38
81 INT147525 Gene_expression of Tacr2 4 0.37 2.34 2.35
82 INT133567 Regulation of IL18 11 0.50 9.54 2.31
83 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
84 INT91046 Negative_regulation of Regulation of Tacr1 3 0.40 1.33 2.31
85 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
86 INT98898 Localization of Tacr1 6 0.72 2.47 2.25
87 INT148152 Binding of Il18 4 0.46 4.44 2.19
88 INT104548 Positive_regulation of Positive_regulation of Il18 7 0.66 5.74 2.13
89 INT94128 Positive_regulation of Gene_expression of Il18 6 0.50 3.64 2.06
90 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
91 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05
92 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
93 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02
94 INT136471 Phosphorylation of Tacr1 4 0.46 1.03 1.99
95 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
96 INT155807 Positive_regulation of Gene_expression of Ccl4 8 0.40 5.13 1.9
97 INT75177 Negative_regulation of Tacr2 3 0.08 1.05 1.83
98 INT64530 Negative_regulation of Positive_regulation of Pde2a 1 0.36 0 1.81
99 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77
100 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
101 INT12781 Regulation of Pde2a 4 0.23 1.14 1.69
102 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
103 INT124337 Gene_expression of Tacr2 4 0.66 0.57 1.68
104 INT80162 Localization of Ucn 6 0.80 0.6 1.66
105 INT64529 Localization of Pde2a 1 0.59 0 1.63
106 INT38856 Positive_regulation of Ccl4 24 0.69 9.55 1.62
107 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
108 INT1580 Negative_regulation of Pde2a 7 0.52 3.26 1.59
109 INT188855 Positive_regulation of Gene_expression of Pde2a 5 0.12 1.97 1.53
110 INT48773 Binding of Tacr2 5 0.46 1.22 1.53
111 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
112 INT159978 Regulation of Gene_expression of Tacr2 1 0.29 1.24 1.49
113 INT173717 Gene_expression of Ccl4 22 0.65 13.98 1.47
114 INT14856 Regulation of Negative_regulation of Tacr1 1 0.20 0.21 1.46
115 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
116 INT8812 Localization of Tacr2 2 0.29 0.33 1.39
117 INT167678 Localization of Ccl4 3 0.52 2.22 1.37
118 INT100569 Positive_regulation of Binding of Tacr1 1 0.50 0.66 1.37
119 INT14195 Localization of Pde2a 4 0.16 0.34 1.33
120 INT159598 Positive_regulation of Transcription of IL18 3 0.48 1.84 1.32
121 INT69037 Regulation of Gene_expression of IL18 4 0.43 3.29 1.31
122 INT49204 Protein_catabolism of Tacr1 3 0.50 0.84 1.24
123 INT48289 Regulation of Tacr2 4 0.60 0.35 1.2
124 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
125 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
126 INT65124 Negative_regulation of Positive_regulation of Tacr1 3 0.53 0.9 1.18
127 INT176379 Regulation of Binding of IL18 1 0.37 2.37 1.17
128 INT47348 Binding of Ccl4 8 0.37 3.24 1.08
129 INT35174 Positive_regulation of Localization of IL18 7 0.69 5.22 1.08
130 INT39703 Regulation of Ccl4 3 0.39 0.39 1.08
131 INT7834 Gene_expression of Pde2a 5 0.51 1.9 1.01
132 INT5805 Positive_regulation of Tacr2 5 0.66 0.24 1
133 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
134 INT219031 Positive_regulation of Regulation of Tacr1 1 0.26 0.65 0.95
135 INT188851 Regulation of Gene_expression of Pde2a 1 0.04 0.75 0.94
136 INT275518 Binding of Ccl4 3 0.26 2.74 0.93
137 INT14935 Regulation of Binding of Tacr1 1 0.24 0 0.88
138 INT252286 Phosphorylation of Il18 2 0.79 2.22 0.86
139 INT132587 Negative_regulation of Gene_expression of Tacr1 3 0.57 1.22 0.85
140 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
141 INT80159 Gene_expression of Ucn 3 0.67 0.47 0.82
142 INT89776 Positive_regulation of Pde2a 2 0.47 2.84 0.81
143 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
144 INT98275 Negative_regulation of PDE2A 4 0.17 3.96 0.79
145 INT177533 Negative_regulation of Binding of Pde3a 1 0.21 2.46 0.76
146 INT165240 Negative_regulation of Transcription of Tacr1 3 0.42 0.81 0.74
147 INT163786 Regulation of Gene_expression of Il18 1 0.28 0.88 0.74
148 INT163788 Negative_regulation of Regulation of Il18 1 0.27 0.87 0.73
149 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
150 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
151 INT138489 Negative_regulation of Il18 1 0.02 0.48 0.7
152 INT178818 Regulation of Gene_expression of Il18 3 0.40 2.98 0.68
153 INT183161 Regulation of Pde2a 2 0.05 0.5 0.67
154 INT162911 Gene_expression of PDE3A 2 0.24 2.47 0.65
155 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
156 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
157 INT167854 Positive_regulation of Regulation of Tacr1 1 0.41 0 0.59
158 INT51159 Positive_regulation of Binding of Tacr1 1 0.34 0.17 0.59
159 INT167857 Positive_regulation of Localization of Tacr1 1 0.44 0 0.59
160 INT120190 Negative_regulation of Ccl4 5 0.41 3.17 0.57
161 INT182050 Negative_regulation of Gene_expression of Il18 4 0.57 1.98 0.56
162 INT80160 Negative_regulation of Ucn 2 0.58 0.29 0.56
163 INT99832 Regulation of Negative_regulation of Tacr1 2 0.27 1.28 0.56
164 INT51157 Regulation of Binding of Tacr1 1 0.31 0.2 0.56
165 INT75814 Regulation of Positive_regulation of PDE2A 1 0.23 0.26 0.56
166 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
167 INT98814 Negative_regulation of Ucn 2 0.27 0.14 0.55
168 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
169 INT122186 Binding of Ucn 2 0.23 0.37 0.53
170 INT80163 Positive_regulation of Gene_expression of Ucn 1 0.50 0.41 0.52
171 INT322701 Positive_regulation of Binding of Ccl4 1 0.33 0.18 0.52
172 INT322706 Negative_regulation of Binding of Ccl4 1 0.28 0.18 0.52
173 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
174 INT176384 Positive_regulation of Binding of IL18 1 0.41 0.98 0.51
175 INT252287 Positive_regulation of Phosphorylation of Il18 1 0.13 0.59 0.49
176 INT205689 Protein_catabolism of Il18 2 0.23 0.8 0.47
177 INT219033 Regulation of Transcription of Tacr1 1 0.15 0.62 0.46
178 INT162903 Localization of PDE2A 2 0.61 0.89 0.45
179 INT137942 Negative_regulation of Gene_expression of Tacr2 2 0.37 0.13 0.44
180 INT121469 Binding of Pde3a 2 0.23 1.42 0.44
181 INT216759 Binding of PDE2A 1 0.00 0.08 0.44
182 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
183 INT123831 Regulation of Ucn 2 0.42 0 0.42
184 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
185 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
186 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
187 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
188 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
189 INT205684 Negative_regulation of Localization of Il18 1 0.13 0.61 0.39
190 INT91668 Positive_regulation of Negative_regulation of IL18 1 0.38 0.24 0.38
191 INT168788 Positive_regulation of Positive_regulation of Il18 1 0.16 0.73 0.38
192 INT182047 Negative_regulation of Negative_regulation of Il18 1 0.42 0.74 0.37
193 INT235122 Negative_regulation of Positive_regulation of PDE2A 1 0.01 0.72 0.35
194 INT235113 Positive_regulation of Negative_regulation of PDE2A 1 0.01 0.72 0.35
195 INT135945 Positive_regulation of Positive_regulation of PDE2A 2 0.12 0.78 0.34
196 INT205688 Regulation of Localization of Il18 1 0.08 0.59 0.34
197 INT329566 Negative_regulation of Gene_expression of Ccl4 4 0.37 2.05 0.33
198 INT181416 Negative_regulation of Ccl4 3 0.26 2.34 0.32
199 INT219588 Negative_regulation of Gene_expression of Pde3a 1 0.25 0 0.32
200 INT84195 Negative_regulation of Binding of Tacr1 1 0.02 0 0.32
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