GO:0043139

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Name 5'-3' DNA helicase activity
Categary Function
Go Slim No
Go Link GO:0043139
Unique Molecular Interactions 10
Total Molecular Interactions 17
Total Single Events 47
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 5'-3' DNA helicase activity. They are ordered first by their pain relevance and then by number of times they were reported for 5'-3' DNA helicase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
2 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
3 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
4 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
5 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
6 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
7 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
8 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0
9 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
10 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 5'-3' DNA helicase activity. They are ordered first by their pain relevance and then by number of times they were reported in 5'-3' DNA helicase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
2 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
3 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
4 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
5 INT251828 Negative_regulation of C10orf2 3 0.37 2.87 0.41
6 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
7 INT302693 Localization of C10orf2 1 0.59 1 0.11
8 INT302695 Negative_regulation of Localization of C10orf2 1 0.33 1 0.11
9 INT251831 Positive_regulation of C10orf2 1 0.50 1.23 0.08
10 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
11 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
12 INT251833 Binding of C10orf2 1 0.37 0.47 0
13 INT149430 Localization of ERCC2 1 0.43 0.76 0
14 INT251826 Gene_expression of C10orf2 1 0.67 0.28 0
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