GO:0043149

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Name stress fiber assembly
Categary Process
Go Slim No
Go Link GO:0043149
Unique Molecular Interactions 100
Total Molecular Interactions 133
Total Single Events 855
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for stress fiber assembly. They are ordered first by their pain relevance and then by number of times they were reported for stress fiber assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
2 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
3 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
4 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
5 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
6 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
7 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
8 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
9 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
10 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
11 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
12 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
13 INT81329 Binding of ARRB1 and OPRK1 1 0.05 0.1 0.93
14 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
15 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
16 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
17 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71
18 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
19 INT94366 Binding of ARRB1 and OPRD1 1 0.11 0 0.67
20 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
21 INT81330 ARRB1 Regulation of OPRK1 1 0.04 0.09 0.47
22 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42
23 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
24 INT116678 Binding of ARRB1 and Oxtr 1 0.13 0.15 0.38
25 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
26 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
27 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
28 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23
29 INT285640 Eln Regulation of Tnfrsf12a 1 0.14 0.16 0.22
30 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
31 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19
32 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
33 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
34 INT319311 Binding of Glud1 and Ptk2b 1 0.36 0 0.19
35 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
36 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
37 INT161547 Trpv1 Regulation of Sorbs1 1 0.03 0.25 0.17
38 INT271444 Binding of Lox and Eln 1 0.21 0.82 0.16
39 INT319314 Binding of Ptk2b and Rbm39 1 0.01 0.08 0.14
40 INT319316 Binding of GRIN1 and Ptk2b 1 0.52 0.08 0.14
41 INT180447 Binding of Rhoa and Car2 1 0.17 0.56 0.13
42 INT241454 Rgnef Positive_regulation of Positive_regulation of Rhoa 1 0.04 0.11 0.13
43 INT254488 Dtx1 Regulation of Sorbs1 1 0.01 0 0.12
44 INT326387 Binding of PROC and Rhoa 1 0.00 0.59 0.12
45 INT241446 Rgnef Positive_regulation of Rhoa 1 0.04 0.1 0.12
46 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
47 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
48 INT180449 Rhoa Regulation of Positive_regulation of Car2 1 0.13 0 0.09
49 INT180443 Rhoa Regulation of Negative_regulation of Mlc1 1 0.04 0 0.09
50 INT355604 VEGFA Regulation of Positive_regulation of Ptk2b 1 0.22 1.47 0.08
51 INT243309 TNFAIP1 Positive_regulation of Localization of TNF 1 0.07 0.71 0.08
52 INT243313 TNFAIP1 Positive_regulation of TNF 1 0.31 0.71 0.08
53 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07
54 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07
55 INT319309 Egr2 Regulation of Ptk2b 1 0.29 0.37 0.07
56 INT333256 Gene_expression of Cxcl12 Negative_regulation of Ptk2b 1 0.10 0.99 0.07
57 INT326377 Ezr Positive_regulation of Positive_regulation of Rhoa 1 0.05 0.16 0.06
58 INT326378 Binding of Rhoa and Ezr 1 0.04 0.17 0.06
59 INT326384 Slc9a3r2 Positive_regulation of Positive_regulation of Rhoa 1 0.03 0.16 0.05
60 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
61 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
62 INT202928 Binding of Eln and Fbln2 1 0.11 0.29 0.04
63 INT271452 Binding of TGFB1 and Eln 1 0.00 0.38 0.04
64 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
65 INT202929 Binding of Eln and Fbln1 1 0.09 0.21 0.03
66 INT180438 Positive_regulation of Rhoa Positive_regulation of Car2 1 0.22 0.48 0.03
67 INT241450 Binding of Rhoa and Dpysl3 1 0.02 0 0.03
68 INT288829 Binding of Rhoa and Rac1 2 0.21 1.88 0
69 INT326383 Binding of Rhoa and Gopc 2 0.04 0.89 0
70 INT254849 Negative_regulation of Rhoa Positive_regulation of Phosphorylation of Smad3 1 0.11 0.45 0
71 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
72 INT180446 Rhoa Regulation of Gene_expression of Car2 1 0.21 0.17 0
73 INT334472 Gopc Regulation of Positive_regulation of Rhoa 1 0.02 0.3 0
74 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
75 INT191698 Binding of TAT and SORBS1 1 0.01 1.08 0
76 INT254851 C3 Negative_regulation of Rhoa 1 0.06 0 0
77 INT254848 Tgfb1 Negative_regulation of Rhoa 1 0.02 0 0
78 INT342432 Binding of Rhoa and Positive_regulation of Atp9a 1 0.20 0 0
79 INT334469 Gopc Regulation of Localization of Rhoa 1 0.02 0.3 0
80 INT254854 Positive_regulation of C3 Negative_regulation of Rhoa 1 0.05 0 0
81 INT334473 PGGT1B Regulation of Localization of Rhoa 1 0.04 0.47 0
82 INT173127 Binding of INS and SORBS1 1 0.02 0.22 0
83 INT305986 Binding of Nfe2l2 and Cul3 1 0.39 0.44 0
84 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
85 INT254865 Rhoa Positive_regulation of Fbrs 1 0.08 0.81 0
86 INT228005 Binding of Eln and Loxl1 1 0.35 1.58 0
87 INT228006 Positive_regulation of Binding of Eln and Loxl1 1 0.37 0.55 0
88 INT254864 Rhoa Positive_regulation of Egfl7 1 0.02 0.82 0
89 INT334468 Rhoa Regulation of Localization of Rac1 1 0.25 0.18 0
90 INT161548 Sorbs1 Positive_regulation of Gene_expression of Ros1 1 0.22 0.07 0
91 INT254853 Rhoa Positive_regulation of Rac1 1 0.10 0.81 0
92 INT180125 Rhoa Positive_regulation of Rock1 1 0.14 0 0
93 INT201741 Binding of Rhoa and Ngfr 1 0.01 1 0
94 INT180439 Rhoa Regulation of Gene_expression of Acot1 1 0.07 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for stress fiber assembly. They are ordered first by their pain relevance and then by number of times they were reported in stress fiber assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63
2 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
3 INT8533 Regulation of Sorbs1 9 0.27 3.01 11.98
4 INT8535 Localization of Sorbs1 9 0.80 2.71 9.07
5 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36
6 INT72539 Gene_expression of Sorbs1 10 0.78 4.98 8.14
7 INT77404 Gene_expression of ARRB1 19 0.62 1.53 7.22
8 INT77408 Binding of ARRB1 11 0.36 0.31 6.51
9 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61
10 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
11 INT8536 Binding of Sorbs1 2 0.14 1.24 3.64
12 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
13 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
14 INT106833 Positive_regulation of ARRB1 4 0.39 1.21 2.71
15 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
16 INT122060 Positive_regulation of Positive_regulation of Sorbs1 2 0.34 0.06 2.57
17 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
18 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
19 INT77396 Regulation of ARRB1 6 0.35 2.04 2.22
20 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
21 INT8537 Negative_regulation of Regulation of Sorbs1 1 0.18 0 2.17
22 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
23 INT77410 Positive_regulation of Gene_expression of ARRB1 3 0.55 0.21 1.98
24 INT275860 Negative_regulation of Localization of TNFAIP1 1 0.03 4.41 1.91
25 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
26 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85
27 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
28 INT179670 Protein_catabolism of Eln 3 0.19 6.16 1.84
29 INT113539 Positive_regulation of Binding of ARRB1 1 0.02 0.11 1.72
30 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
31 INT243339 Localization of TNFAIP1 4 0.41 3.7 1.39
32 INT77398 Negative_regulation of ARRB1 1 0.47 0 1.31
33 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
34 INT106830 Positive_regulation of Positive_regulation of ARRB1 1 0.16 0.13 1.28
35 INT180763 Positive_regulation of Binding of Sorbs1 1 0.02 1.25 1.26
36 INT180762 Negative_regulation of Binding of Sorbs1 1 0.02 1.24 1.26
37 INT319293 Phosphorylation of Ptk2b 9 0.80 3.14 1.24
38 INT22235 Gene_expression of Eln 11 0.76 5.4 1.23
39 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
40 INT106832 Localization of ARRB1 2 0.22 0.3 1.21
41 INT77411 Regulation of Gene_expression of ARRB1 3 0.36 0.61 1.12
42 INT106835 Positive_regulation of Localization of ARRB1 1 0.15 0.11 1.04
43 INT92988 Protein_catabolism of Eln 6 0.47 5.48 1.03
44 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
45 INT135032 Negative_regulation of SRF 1 0.49 0 1.03
46 INT290411 Gene_expression of Ptk2b 10 0.65 3.72 1.01
47 INT180423 Positive_regulation of Gene_expression of Rhoa 7 0.40 6.22 0.98
48 INT236927 Positive_regulation of Ptk2b 9 0.67 3.41 0.94
49 INT26531 Regulation of Srf 3 0.18 0.62 0.9
50 INT266561 Negative_regulation of Positive_regulation of Sorbs1 1 0.01 1.01 0.88
51 INT146195 Positive_regulation of Localization of Rhoa 4 0.45 2.67 0.84
52 INT44955 Negative_regulation of Eln 8 0.42 3.79 0.83
53 INT231380 Negative_regulation of Phosphorylation of Rhoa 1 0.13 1.28 0.79
54 INT85678 Binding of Arrb1 1 0.20 0.09 0.78
55 INT82928 Positive_regulation of Eln 7 0.69 3.54 0.77
56 INT45293 Transcription of Srf 2 0.47 0.79 0.76
57 INT181326 Binding of TNFAIP1 2 0.29 0.81 0.74
58 INT231369 Phosphorylation of Rhoa 1 0.25 1.22 0.73
59 INT116081 Negative_regulation of Binding of ARRB1 1 0.41 0 0.72
60 INT45489 Gene_expression of SRF 5 0.77 3.29 0.71
61 INT77406 Negative_regulation of Negative_regulation of ARRB1 1 0.47 0 0.71
62 INT77401 Regulation of Regulation of ARRB1 1 0.25 0 0.69
63 INT179653 Localization of Eln 3 0.15 2.75 0.65
64 INT230410 Negative_regulation of Gene_expression of TNFAIP1 3 0.16 3.67 0.63
65 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
66 INT179661 Gene_expression of Eln 9 0.56 7.59 0.58
67 INT316940 Positive_regulation of Phosphorylation of Rhoa 1 0.41 0.41 0.58
68 INT316931 Phosphorylation of Rhoa 1 0.48 0.41 0.57
69 INT140368 Positive_regulation of Positive_regulation of Rhoa 3 0.69 0.2 0.56
70 INT180420 Negative_regulation of Gene_expression of Rhoa 3 0.37 1.65 0.55
71 INT180422 Regulation of Gene_expression of Rhoa 2 0.39 0.6 0.55
72 INT181325 Positive_regulation of TNFAIP1 4 0.36 4.64 0.52
73 INT323479 Phosphorylation of Sorbs1 1 0.06 1.8 0.49
74 INT319254 Localization of Ptk2b 1 0.78 0.26 0.46
75 INT140373 Binding of Rhoa 3 0.48 0.28 0.45
76 INT319284 Binding of Ptk2b 1 0.36 0.9 0.45
77 INT122162 Localization of Eln 2 0.69 0.81 0.44
78 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
79 INT179654 Positive_regulation of Eln 5 0.44 4.3 0.43
80 INT162531 Binding of Eln 4 0.43 3.8 0.42
81 INT319286 Transcription of Ptk2b 1 0.52 1.17 0.4
82 INT27554 Regulation of Eln 6 0.52 6.76 0.39
83 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
84 INT156120 Localization of Arrb1 1 0.00 0 0.38
85 INT156119 Positive_regulation of Localization of Arrb1 1 0.00 0 0.38
86 INT254484 Positive_regulation of Gene_expression of Sorbs1 4 0.12 1.9 0.37
87 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
88 INT119229 Positive_regulation of Protein_catabolism of Eln 2 0.24 1.8 0.32
89 INT319276 Positive_regulation of Phosphorylation of Ptk2b 1 0.49 0.62 0.32
90 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
91 INT7610 Localization of Srf 3 0.67 0.98 0.27
92 INT140371 Positive_regulation of Negative_regulation of Rhoa 1 0.46 0 0.26
93 INT142864 Positive_regulation of Phosphorylation of ARRB1 1 0.01 0 0.25
94 INT142865 Phosphorylation of ARRB1 1 0.01 0 0.25
95 INT109859 Localization of Rhoa 3 0.54 1.09 0.24
96 INT179671 Binding of Eln 5 0.31 5.32 0.23
97 INT289343 Regulation of Gene_expression of Rhoa 1 0.13 0.28 0.23
98 INT140365 Negative_regulation of Protein_catabolism of Rhoa 1 0.43 0 0.23
99 INT140358 Negative_regulation of Positive_regulation of Rhoa 1 0.43 0 0.23
100 INT289342 Negative_regulation of Gene_expression of Rhoa 1 0.20 0.28 0.23
101 INT289353 Positive_regulation of Gene_expression of Rhoa 1 0.23 0.28 0.23
102 INT180415 Regulation of Rhoa 7 0.53 3.92 0.22
103 INT274219 Positive_regulation of Gene_expression of Eln 4 0.06 2.69 0.22
104 INT140359 Positive_regulation of Protein_catabolism of Rhoa 1 0.69 0 0.22
105 INT140369 Protein_catabolism of Rhoa 1 0.99 0 0.22
106 INT180418 Binding of Rhoa 16 0.32 7.05 0.2
107 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
108 INT20828 Positive_regulation of Negative_regulation of TNFAIP1 1 0.36 0.1 0.19
109 INT319247 Regulation of Ptk2b 1 0.60 0 0.18
110 INT140361 Regulation of Positive_regulation of Rhoa 1 0.45 0 0.17
111 INT179672 Positive_regulation of Localization of Eln 1 0.07 1.1 0.17
112 INT89766 Binding of SRF 1 0.17 0.89 0.15
113 INT89767 Positive_regulation of Binding of SRF 1 0.23 0.89 0.15
114 INT274220 Negative_regulation of Gene_expression of Eln 1 0.05 2.6 0.13
115 INT179657 Negative_regulation of Binding of Eln 1 0.05 0.93 0.13
116 INT179664 Negative_regulation of Eln 3 0.19 2.35 0.12
117 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
118 INT181323 Regulation of TNFAIP1 4 0.35 0.92 0.11
119 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
120 INT282407 Transcription of Rhoa 1 0.15 0.52 0.1
121 INT92191 Positive_regulation of Positive_regulation of Eln 1 0.15 0.54 0.1
122 INT259603 Positive_regulation of Gene_expression of Eln 1 0.10 0.3 0.08
123 INT109862 Negative_regulation of Localization of Rhoa 1 0.33 0.37 0.08
124 INT22789 Binding of Srf 1 0.37 0.07 0.07
125 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
126 INT190544 Transcription of Srf 1 0.19 0.43 0.06
127 INT190570 Localization of Srf 1 0.20 0.49 0.06
128 INT126629 Negative_regulation of Transcription of Rhoa 1 0.33 0 0.05
129 INT303892 Regulation of Negative_regulation of Eln 1 0.08 0.32 0.05
130 INT180419 Regulation of Positive_regulation of Rhoa 2 0.39 0.9 0.04
131 INT274221 Regulation of Gene_expression of Eln 1 0.04 0.82 0.04
132 INT126630 Transcription of Rhoa 1 0.54 0 0.04
133 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
134 INT268102 Transcription of SRF 1 0.53 0.85 0.03
135 INT225413 Binding of Srf 1 0.10 0.27 0.03
136 INT157800 Gene_expression of Srf 2 0.45 0.88 0
137 INT200683 Gene_expression of PTK2B 2 0.67 1.02 0
138 INT173193 Binding of SORBS1 2 0.14 1.29 0
139 INT181322 Positive_regulation of Gene_expression of TNFAIP1 2 0.39 3.28 0
140 INT105753 Positive_regulation of Gene_expression of SRF 1 0.01 0.13 0
141 INT271433 Transcription of Eln 1 0.55 1.19 0
142 INT243389 Transcription of PTK2B 1 0.64 0.52 0
143 INT181324 Regulation of Gene_expression of TNFAIP1 1 0.35 0 0
144 INT200665 Negative_regulation of Gene_expression of PTK2B 1 0.04 0.69 0
145 INT212954 Positive_regulation of Negative_regulation of Rhoa 1 0.19 1.18 0
146 INT236340 Negative_regulation of Positive_regulation of Eln 1 0.01 0.92 0
147 INT313615 Positive_regulation of Negative_regulation of Eln 1 0.02 0.07 0
148 INT191647 Regulation of Regulation of Rhoa 1 0.13 0.32 0
149 INT179652 Positive_regulation of Protein_catabolism of Eln 1 0.05 0.93 0
150 INT105752 Positive_regulation of SRF 1 0.01 0.13 0
151 INT268104 Negative_regulation of Gene_expression of SRF 1 0.38 0.16 0
152 INT213446 Regulation of Gene_expression of SRF 1 0.22 0.71 0
153 INT334441 Regulation of Localization of Rhoa 1 0.33 0.88 0
154 INT225408 Negative_regulation of Srf 1 0.05 0.39 0
155 INT179655 Negative_regulation of Protein_catabolism of Eln 1 0.05 0.93 0
156 INT156922 Positive_regulation of Phosphorylation of PTK2B 1 0.23 0 0
157 INT339743 Positive_regulation of SORBS1 1 0.06 0.39 0
158 INT157799 Negative_regulation of Gene_expression of Srf 1 0.18 0.07 0
159 INT290418 Regulation of Gene_expression of Ptk2b 1 0.17 0.1 0
160 INT157794 Phosphorylation of Srf 1 0.26 0.07 0
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