GO:0043196

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Name varicosity
Categary Component
Go Slim No
Go Link GO:0043196
Unique Molecular Interactions 299
Total Molecular Interactions 510
Total Single Events 3596
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for varicosity. They are ordered first by their pain relevance and then by number of times they were reported for varicosity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
2 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
3 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
4 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
5 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
6 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
7 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
8 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
9 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
10 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
11 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
12 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
13 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
14 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
15 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
16 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
17 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
18 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
19 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
20 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
21 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
22 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
23 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
24 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
25 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
26 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
27 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
28 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
29 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
30 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
31 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
32 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
33 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
34 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
35 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
36 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
37 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
38 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
39 INT289659 Tnfrsf1b Negative_regulation of Mcpt3 1 0.02 0.82 1.13
40 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
41 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
42 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
43 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1
44 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
45 INT31549 Binding of Dbh and Vip 1 0.32 0 1.08
46 INT356316 Crh Positive_regulation of Localization of Cea 1 0.34 0 1.06
47 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
48 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
49 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
50 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
51 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
52 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
53 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96
54 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96
55 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
56 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91
57 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
58 INT21006 Oprl1 Regulation of Localization of Crh 1 0.19 0 0.84
59 INT64629 Binding of Gal and Crh 1 0.18 0.1 0.83
60 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
61 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
62 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8
63 INT36003 Crh Positive_regulation of Localization of LH 2 0.45 0 0.79
64 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76
65 INT28620 Penk Regulation of Crh 2 0.40 0.25 0.75
66 INT30838 Crh Negative_regulation of D230030E09Rik 1 0.17 0.1 0.73
67 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73
68 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
69 INT290553 Positive_regulation of Oprk1 Positive_regulation of Crh 1 0.33 0.39 0.72
70 INT187171 Binding of Tnfrsf1b and Gtf3a 1 0.03 2.15 0.72
71 INT5971 Il1a Positive_regulation of Crh 2 0.51 0.57 0.71
72 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71
73 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71
74 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
75 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 0.38 0 0.7
76 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
77 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
78 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69
79 INT253830 Cck Positive_regulation of Crh 1 0.38 0 0.68
80 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
81 INT135119 Binding of Pomc and Crh 1 0.35 0 0.67
82 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
83 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
84 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
85 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64
86 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
87 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
88 INT34212 PSG2 Regulation of Localization of Crh 1 0.02 0.09 0.63
89 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
90 INT142432 Regulation of Cp Positive_regulation of Crh 1 0.18 0.75 0.63
91 INT23576 Binding of Penk and Crh 2 0.18 0 0.62
92 INT20162 Crh Regulation of GNRH1 2 0.02 0.07 0.62
93 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
94 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61
95 INT356328 Crh Positive_regulation of Cea 1 0.26 0.28 0.6
96 INT57246 Crh Positive_regulation of Positive_regulation of Caprin2 1 0.01 0.55 0.6
97 INT104050 Binding of Crh and Nts 1 0.40 0 0.6
98 INT59540 Crh Regulation of Gnrh1 2 0.36 2.61 0.58
99 INT356315 Crh Regulation of Cea 1 0.16 0.08 0.58
100 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
101 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
102 INT62445 Pomc Negative_regulation of Localization of Crh 1 0.12 0.07 0.58
103 INT30268 Binding of Gnrh1 and Crh 1 0.45 0.65 0.57
104 INT356311 Crh Regulation of Gabrg1 1 0.08 0.08 0.57
105 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57
106 INT30267 Binding of Crh and Gnrhr 1 0.33 0.65 0.57
107 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
108 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
109 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55
110 INT60627 Crh Positive_regulation of Localization of Mc2r 2 0.11 0.44 0.53
111 INT139750 Ubqln1 Regulation of Dbh 1 0.00 0 0.52
112 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
113 INT139751 Dbh Regulation of Localization of Prl 1 0.02 0 0.52
114 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
115 INT55208 Prl Negative_regulation of Localization of Crh 1 0.43 0 0.51
116 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51
117 INT62446 Il6 Positive_regulation of Crh 1 0.22 0.05 0.5
118 INT27066 Crh Positive_regulation of Localization of Oxt 1 0.40 0 0.48
119 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
120 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
121 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
122 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
123 INT28619 Negative_regulation of Penk Regulation of Crh 1 0.41 0 0.46
124 INT62447 Gnrh1 Regulation of Localization of Crh 1 0.40 0.17 0.45
125 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
126 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
127 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44
128 INT30083 Binding of Crh and Lvp1 1 0.00 0.35 0.44
129 INT290543 Binding of Crh and Pdyn 1 0.25 1.04 0.43
130 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43
131 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42
132 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42
133 INT55202 Crh Positive_regulation of Negative_regulation of Prl 1 0.51 0 0.41
134 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
135 INT273939 Positive_regulation of Crem Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39
136 INT273956 Binding of Crem and Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39
137 INT34856 Hpd Negative_regulation of Dbh 1 0.00 0 0.39
138 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38
139 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
140 INT356319 ORF61 Regulation of Crh 1 0.00 0.1 0.38
141 INT25763 Crh Positive_regulation of Prkacb 1 0.56 0.07 0.37
142 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36
143 INT26197 Qrfp Regulation of Localization of Crh 1 0.02 0 0.36
144 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36
145 INT66368 Pomc Regulation of Positive_regulation of Crh 1 0.36 0 0.35
146 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34
147 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
148 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
149 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
150 INT280838 Binding of Crh and gr 1 0.06 0 0.33
151 INT30418 Crh Negative_regulation of Localization of Gh1 1 0.41 0.72 0.33
152 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33
153 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33
154 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33
155 INT26196 Npy Positive_regulation of Localization of Crh 1 0.40 0 0.33
156 INT60628 Crh Positive_regulation of Pomc 1 0.52 0.17 0.32
157 INT251582 TNF Positive_regulation of Tnfrsf1b 1 0.29 2.11 0.32
158 INT26071 Adarb1 Regulation of Localization of Crh 1 0.01 0.21 0.32
159 INT30420 Crh Positive_regulation of Localization of Gh1 1 0.67 0.47 0.32
160 INT107944 Crh Regulation of Adarb1 1 0.06 0 0.32
161 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31
162 INT141019 Crh Positive_regulation of Gene_expression of Pomc 1 0.20 0.1 0.31
163 INT290552 Crh Positive_regulation of Positive_regulation of Pdyn 1 0.38 0.23 0.3
164 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29
165 INT74331 Crh Regulation of Transcription of Penk 1 0.40 0.25 0.29
166 INT74335 Penk Regulation of Transcription of Crh 1 0.40 0.25 0.29
167 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
168 INT42354 Dbh Regulation of Localization of Gh1 1 0.07 0 0.28
169 INT98816 Crhr2 Positive_regulation of Negative_regulation of Ucn 1 0.33 0.09 0.28
170 INT78484 Binding of DBH and TH 1 0.09 0 0.28
171 INT187170 Binding of Ltbr and Tnfrsf1b 1 0.06 0.88 0.28
172 INT74330 Crh Regulation of Transcription of Fos 1 0.49 0.24 0.28
173 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27
174 INT273953 Crem Regulation of Transcription of Crh 1 0.26 0.99 0.27
175 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27
176 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25
177 INT56978 Crh Positive_regulation of Localization of Gnrh1 1 0.10 0 0.24
178 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
179 INT154523 Binding of Oxt and Crh 1 0.11 0 0.24
180 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22
181 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
182 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
183 INT92205 Crh Positive_regulation of Localization of SST 1 0.30 0.87 0.21
184 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
185 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21
186 INT33560 Binding of POMC and Crh 1 0.24 0.22 0.2
187 INT62451 Il2 Regulation of Localization of Crh 1 0.53 0.19 0.2
188 INT216041 Binding of Tnfrsf1b and Rtn4r 1 0.10 0.75 0.2
189 INT143394 Ucn Regulation of Crh 1 0.44 0.19 0.2
190 INT280820 S100a8 Positive_regulation of Gene_expression of Crh 1 0.01 0.65 0.19
191 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19
192 INT25053 Crh Regulation of PLOD1 1 0.11 0 0.19
193 INT25052 Crh Regulation of FSHR 1 0.08 0 0.19
194 INT59589 Npy Regulation of Crh 1 0.27 0 0.18
195 INT121045 Crh Regulation of Gene_expression of Pomc 1 0.03 0.16 0.18
196 INT55988 POMC Positive_regulation of Negative_regulation of Crh 1 0.01 0 0.18
197 INT342647 Negative_regulation of Binding of Avp and Crh 1 0.37 0.64 0.18
198 INT59588 Npy Positive_regulation of Crh 1 0.41 0 0.18
199 INT121046 Crh Regulation of Localization of Pomc 1 0.03 0.16 0.18
200 INT59587 Npy Regulation of Gene_expression of Crh 1 0.27 0 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for varicosity. They are ordered first by their pain relevance and then by number of times they were reported in varicosity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1562 Localization of Crh 499 0.81 126.74 236.68
2 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
3 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
4 INT1898 Regulation of Crh 220 0.62 61.33 102.64
5 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
6 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
7 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
8 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
9 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
10 INT16879 Binding of Crh 72 0.48 21.65 28.43
11 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
12 INT21379 Transcription of Crh 65 0.72 15.64 27.92
13 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
14 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23
15 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
16 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
17 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
18 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
19 INT8075 Localization of Crh 64 0.81 25.41 19.45
20 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
21 INT4073 Localization of Dbh 28 0.81 6.06 16.37
22 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
23 INT7585 Regulation of Crh 24 0.58 9.88 12.97
24 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
25 INT87193 Gene_expression of Tnfrsf1b 30 0.58 29.4 9.22
26 INT3922 Negative_regulation of Pnmt 29 0.59 3.18 8.96
27 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01
28 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
29 INT21179 Negative_regulation of Crh 22 0.58 8.03 7.87
30 INT47546 Binding of Dbh 11 0.44 5.69 7.84
31 INT151823 Binding of Tnfrsf1b 19 0.42 17.92 7.31
32 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
33 INT23132 Positive_regulation of Pnmt 17 0.67 2.02 6.84
34 INT77789 Positive_regulation of Tnfrsf1b 12 0.65 13.77 6.58
35 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46
36 INT133638 Gene_expression of Dbh 9 0.78 1.23 5.46
37 INT18244 Regulation of Positive_regulation of Crh 11 0.45 3.87 5.41
38 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24
39 INT124976 Positive_regulation of Tnfrsf1b 15 0.67 14.92 5.15
40 INT14455 Transcription of Pnmt 17 0.72 2.13 4.95
41 INT97894 Positive_regulation of Gene_expression of Crh 27 0.70 11.82 4.82
42 INT113373 Positive_regulation of Gene_expression of Tnfrsf1b 15 0.65 8.64 4.79
43 INT12380 Localization of Pnmt 10 0.80 0.07 4.7
44 INT19777 Binding of Crh 16 0.40 6.65 4.36
45 INT134008 Transcription of Crh 8 0.59 6.12 3.95
46 INT63441 Regulation of Transcription of Crh 9 0.60 4.51 3.9
47 INT18538 Regulation of Pnmt 11 0.60 1.03 3.84
48 INT5400 Positive_regulation of DBH 6 0.70 2.02 3.38
49 INT140107 Negative_regulation of Tnfrsf1b 6 0.36 6.11 3.2
50 INT103739 Negative_regulation of Gene_expression of Crh 19 0.59 10.19 3.17
51 INT15253 Binding of DBH 7 0.36 3.21 3.17
52 INT28715 Negative_regulation of Regulation of Crh 7 0.43 0.97 3.06
53 INT46291 Negative_regulation of Dbh 6 0.56 0.91 3.06
54 INT54740 Positive_regulation of Localization of Crh 10 0.47 7.27 3.01
55 INT124974 Regulation of Tnfrsf1b 4 0.59 4.59 3.01
56 INT28376 Regulation of Localization of Dbh 1 0.31 0 2.87
57 INT184255 Binding of Tnfrsf1b 4 0.43 4.45 2.78
58 INT235853 Regulation of Gene_expression of Crh 7 0.51 1.98 2.66
59 INT2958 Transcription of Dbh 4 0.71 2.57 2.64
60 INT5510 Negative_regulation of Negative_regulation of Crh 8 0.43 1.05 2.61
61 INT22339 Positive_regulation of Negative_regulation of Crh 5 0.67 1.36 2.59
62 INT122187 Positive_regulation of Crhr2 3 0.58 2.46 2.56
63 INT122651 Transcription of Tnfrsf1b 6 0.67 3.63 2.49
64 INT2695 Regulation of DBH 5 0.45 1.09 2.48
65 INT94119 Localization of Tnfrsf1b 8 0.75 5.66 2.42
66 INT28971 Positive_regulation of Gene_expression of Dbh 4 0.47 0.58 2.39
67 INT101955 Gene_expression of Crhr2 6 0.64 3.62 2.31
68 INT77784 Regulation of Tnfrsf1b 7 0.57 4.61 2.17
69 INT2961 Regulation of Regulation of Dbh 3 0.24 0.95 2.05
70 INT28468 Positive_regulation of Transcription of Pnmt 4 0.67 0.63 2.04
71 INT100021 Localization of Tnfrsf1b 7 0.80 3.4 1.96
72 INT22087 Negative_regulation of DBH 3 0.59 1.45 1.84
73 INT30834 Regulation of Negative_regulation of Crh 3 0.45 0.62 1.81
74 INT142929 Regulation of Crhr2 1 0.44 1.28 1.73
75 INT29084 Regulation of Localization of Crh 4 0.29 1.24 1.72
76 INT80162 Localization of Ucn 6 0.80 0.6 1.66
77 INT323984 Regulation of Trpm7 2 0.61 0.66 1.64
78 INT18710 Regulation of Regulation of Crh 6 0.60 0.79 1.6
79 INT139334 Regulation of Gene_expression of Tnfrsf1b 2 0.55 3.89 1.6
80 INT196105 Gene_expression of Trpm7 8 0.77 3.03 1.51
81 INT4074 Negative_regulation of Localization of Dbh 4 0.59 0.61 1.48
82 INT133637 Negative_regulation of Gene_expression of Dbh 2 0.43 0.25 1.46
83 INT28478 Regulation of Gene_expression of Pnmt 5 0.44 0 1.41
84 INT101954 Binding of Crhr2 4 0.31 1.23 1.34
85 INT141233 Negative_regulation of Positive_regulation of Dbh 2 0.42 0.39 1.33
86 INT21178 Positive_regulation of Negative_regulation of Crh 1 0.37 0.13 1.28
87 INT151820 Positive_regulation of Binding of Tnfrsf1b 4 0.48 2.49 1.27
88 INT135144 Negative_regulation of Gene_expression of Tnfrsf1b 7 0.40 3.84 1.25
89 INT28888 Positive_regulation of Crhr2 6 0.68 3.8 1.23
90 INT38650 Positive_regulation of Negative_regulation of Dbh 3 0.50 0 1.16
91 INT28469 Positive_regulation of Gene_expression of Pnmt 4 0.49 0.73 1.11
92 INT23716 Localization of DBH 1 0.29 0.06 1.11
93 INT28972 Regulation of Gene_expression of Dbh 2 0.42 0.86 1.08
94 INT25043 Positive_regulation of Regulation of Crh 5 0.50 1 1.06
95 INT87192 Positive_regulation of Gene_expression of Tnfrsf1b 7 0.35 3.66 1.04
96 INT50812 Regulation of Positive_regulation of Dbh 2 0.45 1.04 1
97 INT144087 Positive_regulation of Trpm7 3 0.69 1.23 0.92
98 INT30598 Negative_regulation of Transcription of Dbh 1 0.42 0.35 0.91
99 INT58050 Regulation of Binding of Crh 2 0.42 0.84 0.86
100 INT290532 Gene_expression of Ucn3 1 0.22 0.59 0.83
101 INT80159 Gene_expression of Ucn 3 0.67 0.47 0.82
102 INT104040 Regulation of Crhr2 2 0.36 1.29 0.81
103 INT47518 Negative_regulation of Positive_regulation of Pnmt 2 0.42 0.32 0.8
104 INT355888 Negative_regulation of Trpm7 1 0.58 0.87 0.8
105 INT28974 Negative_regulation of Negative_regulation of Dbh 1 0.40 0 0.78
106 INT101952 Negative_regulation of Crhr2 1 0.17 0.97 0.77
107 INT280771 Positive_regulation of Positive_regulation of Crh 2 0.41 0.21 0.76
108 INT133639 Positive_regulation of Gene_expression of Dbh 1 0.50 0 0.75
109 INT2959 Regulation of Transcription of Dbh 2 0.45 1.18 0.73
110 INT140282 Negative_regulation of Positive_regulation of Crh 3 0.39 1.09 0.71
111 INT12379 Regulation of Localization of Pnmt 1 0.17 0 0.69
112 INT4072 Positive_regulation of Positive_regulation of Dbh 3 0.50 1.77 0.67
113 INT142429 Positive_regulation of Transcription of Crh 1 0.47 0.73 0.67
114 INT134009 Regulation of Transcription of Crh 2 0.37 1.1 0.66
115 INT28889 Transcription of Crhr2 2 0.64 1.13 0.66
116 INT25761 Regulation of Positive_regulation of Crh 1 0.45 0.15 0.65
117 INT80160 Negative_regulation of Ucn 2 0.58 0.29 0.56
118 INT98814 Negative_regulation of Ucn 2 0.27 0.14 0.55
119 INT101949 Negative_regulation of Binding of Crhr2 1 0.24 0.6 0.55
120 INT122186 Binding of Ucn 2 0.23 0.37 0.53
121 INT80163 Positive_regulation of Gene_expression of Ucn 1 0.50 0.41 0.52
122 INT3381 Positive_regulation of Regulation of Dbh 2 0.44 0.37 0.47
123 INT187167 Transcription of Tnfrsf1b 2 0.69 0.92 0.46
124 INT134393 Regulation of Dbh 1 0.44 0.44 0.46
125 INT19776 Positive_regulation of Binding of Crh 1 0.43 0 0.44
126 INT305077 Localization of CRHBP 1 0.76 0.28 0.44
127 INT133179 Transcription of DBH 1 0.70 0.23 0.44
128 INT355892 Negative_regulation of Gene_expression of Trpm7 1 0.51 0.66 0.44
129 INT123831 Regulation of Ucn 2 0.42 0 0.42
130 INT148784 Negative_regulation of Crhr2 2 0.40 0.76 0.42
131 INT83897 Protein_catabolism of Crh 2 0.86 1.75 0.39
132 INT122648 Positive_regulation of Transcription of Tnfrsf1b 2 0.43 1.01 0.39
133 INT47547 Positive_regulation of Binding of Dbh 1 0.47 0 0.39
134 INT144599 Gene_expression of Crhr2 3 0.49 2.16 0.36
135 INT77787 Regulation of Positive_regulation of Tnfrsf1b 1 0.08 0.84 0.36
136 INT251551 Negative_regulation of Gene_expression of Tnfrsf1b 1 0.30 0.85 0.32
137 INT247097 Binding of CRHBP 3 0.34 0.4 0.28
138 INT290535 Negative_regulation of Negative_regulation of Crh 1 0.32 0.19 0.28
139 INT83525 Negative_regulation of Transcription of Pnmt 3 0.57 0 0.27
140 INT280795 Positive_regulation of Ucn 1 0.31 0.06 0.27
141 INT280775 Regulation of Regulation of Crh 1 0.37 0.08 0.27
142 INT122676 Positive_regulation of Ucn 1 0.43 0.92 0.26
143 INT184254 Positive_regulation of Binding of Tnfrsf1b 1 0.47 0.57 0.26
144 INT143391 Gene_expression of Ucn 1 0.67 0.2 0.26
145 INT83526 Negative_regulation of Gene_expression of Pnmt 1 0.41 0 0.25
146 INT273222 Phosphorylation of Bin1 1 0.06 0.62 0.23
147 INT143393 Transcription of Crhr2 1 0.52 0.19 0.21
148 INT13931 Protein_catabolism of Dbh 1 0.58 0 0.2
149 INT55986 Positive_regulation of Binding of Crh 1 0.48 0.76 0.19
150 INT16756 Regulation of Transcription of Pnmt 2 0.39 0.08 0.18
151 INT111306 Negative_regulation of Gene_expression of Dbh 1 0.25 0.45 0.17
152 INT196102 Transcription of Trpm7 1 0.56 0.35 0.17
153 INT112935 Binding of Crhr2 1 0.32 0.33 0.17
154 INT124226 Negative_regulation of Tnfrsf1b 4 0.38 0.66 0.15
155 INT251549 Positive_regulation of Phosphorylation of Tnfrsf1b 1 0.35 0.21 0.14
156 INT139335 Negative_regulation of Positive_regulation of Tnfrsf1b 1 0.38 1.26 0.14
157 INT163408 Negative_regulation of Gene_expression of Crhr2 2 0.27 1.56 0.13
158 INT251558 Phosphorylation of Tnfrsf1b 1 0.58 0.21 0.13
159 INT92090 Negative_regulation of Protein_catabolism of Crh 1 0.04 0.99 0.12
160 INT318349 Regulation of Binding of Tnfrsf1b 1 0.18 0.41 0.1
161 INT253240 Positive_regulation of Positive_regulation of Tnfrsf1b 1 0.38 0.98 0.09
162 INT318341 Regulation of Localization of Tnfrsf1b 1 0.18 0.5 0.09
163 INT66162 Positive_regulation of Binding of Pnmt 1 0.49 0 0.08
164 INT66164 Negative_regulation of Binding of Pnmt 1 0.41 0 0.08
165 INT66163 Binding of Pnmt 1 0.36 0 0.08
166 INT355887 Regulation of Negative_regulation of Trpm7 1 0.45 0 0.08
167 INT280766 Localization of Ucn 1 0.46 0 0.07
168 INT165756 Positive_regulation of Gene_expression of Crhr2 1 0.31 0.62 0.07
169 INT205027 Positive_regulation of Positive_regulation of Crhr2 1 0.58 0.14 0.07
170 INT280768 Localization of Ucn3 1 0.35 0 0.07
171 INT355893 Positive_regulation of Regulation of Trpm7 1 0.46 0.11 0.07
172 INT165755 Regulation of Gene_expression of Crhr2 1 0.28 0.62 0.07
173 INT355891 Positive_regulation of Positive_regulation of Trpm7 1 0.50 0 0.04
174 INT355886 Regulation of Positive_regulation of Trpm7 1 0.27 0.24 0.04
175 INT355889 Negative_regulation of Positive_regulation of Trpm7 1 0.42 0 0.04
176 INT355890 Positive_regulation of Gene_expression of Trpm7 1 0.50 0.17 0.04
177 INT222594 Binding of Ucn 1 0.06 0 0.03
178 INT53238 Negative_regulation of Binding of Crh 1 0.48 0.8 0.03
179 INT237347 Binding of Bin1 1 0.36 0.44 0.03
180 INT252623 Positive_regulation of Negative_regulation of Tnfrsf1b 1 0.30 0.34 0.03
181 INT280784 Negative_regulation of Transcription of Crh 1 0.48 0.25 0
182 INT76171 Regulation of Regulation of Pnmt 1 0.19 0 0
183 INT318355 Positive_regulation of Transcription of Tnfrsf1b 1 0.20 0 0
184 INT205029 Regulation of Gene_expression of Crhr2 1 0.22 1.03 0
185 INT205186 Regulation of Transcription of Tnfrsf1b 1 0.04 0 0
186 INT318339 Negative_regulation of Localization of Tnfrsf1b 1 0.17 0 0
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