GO:0043197

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Name dendritic spine
Categary Component
Go Slim No
Go Link GO:0043197
Unique Molecular Interactions 1585
Total Molecular Interactions 2178
Total Single Events 22451
Pain Genes Associated 125

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dendritic spine. They are ordered first by their pain relevance and then by number of times they were reported for dendritic spine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
2 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
3 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
4 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
5 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
6 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
7 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
8 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
9 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
10 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
11 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
12 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
13 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
14 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
15 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
16 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
17 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
18 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
19 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
20 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
21 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
22 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
23 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
24 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
25 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
26 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
27 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
28 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
29 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
30 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
31 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
32 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
33 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
34 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
35 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
36 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
37 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
38 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94
39 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
40 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
41 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
42 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
43 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
44 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
45 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
46 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
47 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
48 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
49 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
50 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
51 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
52 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
53 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
54 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
55 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
56 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
57 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
58 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
59 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
60 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
61 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
62 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
63 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
64 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
65 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
66 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
67 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
68 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
69 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
70 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
71 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
72 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
73 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
74 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
75 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
76 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
77 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
78 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
79 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
80 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
81 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
82 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
83 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
84 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
85 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
86 INT100816 PPP1R14C Regulation of Ppp1cc 1 0.08 0 1.27
87 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
88 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26
89 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
90 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
91 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
92 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
93 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
94 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
95 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
96 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
97 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
98 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
99 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
100 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
101 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
102 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
103 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
104 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17
105 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
106 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
107 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16
108 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
109 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
110 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
111 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
112 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
113 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
114 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12
115 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
116 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
117 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
118 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11
119 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
120 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
121 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
122 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
123 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
124 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
125 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
126 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
127 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
128 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
129 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
130 INT218846 Ppp1r9a Regulation of Ltp 1 0.15 2.24 1.07
131 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
132 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
133 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
134 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
135 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
136 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
137 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
138 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
139 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
140 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
141 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
142 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
143 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
144 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04
145 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
146 INT162250 Binding of TRPV1 and Grm5 1 0.01 0.8 1.03
147 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03
148 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
149 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02
150 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
151 INT151768 Ngf Positive_regulation of P2rx6 1 0.00 0.81 1.01
152 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
153 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
154 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
155 INT151765 Ngf Positive_regulation of Positive_regulation of P2rx6 1 0.00 0.81 1.01
156 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
157 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
158 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
159 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
160 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
161 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
162 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
163 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
164 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
165 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
166 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
167 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
168 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
169 INT89828 Atp4b Positive_regulation of Localization of Grip2 1 0.10 0.54 0.97
170 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
171 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
172 INT274899 Positive_regulation of P2rx4 Positive_regulation of Localization of Gtf3a 1 0.02 1.67 0.95
173 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
174 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
175 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94
176 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
177 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94
178 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
179 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93
180 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
181 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
182 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
183 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
184 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
185 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
186 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
187 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
188 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
189 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
190 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
191 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
192 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
193 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
194 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
195 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
196 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
197 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
198 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
199 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
200 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9

Single Events

The table below shows the top 100 pain related interactions that have been reported for dendritic spine. They are ordered first by their pain relevance and then by number of times they were reported in dendritic spine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
5 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
6 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
7 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
8 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
9 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
10 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
11 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35
12 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
13 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
14 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
15 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
16 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
17 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
18 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
19 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
20 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
21 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
22 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
23 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
24 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
25 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
26 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
27 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
28 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
29 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
30 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
31 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
32 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
33 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22
34 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
35 INT11246 Binding of Grin1 65 0.48 14.53 36.93
36 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
37 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
38 INT13501 Binding of Drd2 65 0.48 23.76 35.6
39 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
40 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
41 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
42 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
43 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72
44 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
45 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
46 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
47 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
48 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
49 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
50 INT49110 Regulation of Grip2 46 0.61 13.57 30.87
51 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93
52 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
53 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
54 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
55 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
56 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
57 INT4459 Positive_regulation of Arc 74 0.69 33.61 28.29
58 INT73314 Gene_expression of Arc 133 0.78 67.78 27.44
59 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
60 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
61 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99
62 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23
63 INT48832 Positive_regulation of Grip2 48 0.69 12.13 25.99
64 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
65 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
66 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
67 INT12484 Binding of Drd2 45 0.48 15.17 24.72
68 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
69 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
70 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
71 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
72 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
73 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
74 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
75 INT78571 Positive_regulation of Grm5 35 0.69 11.81 22.45
76 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
77 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
78 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
79 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
80 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
81 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
82 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
83 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
84 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
85 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
86 INT49774 Binding of DRD2 48 0.48 17.42 20.73
87 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
88 INT166115 Positive_regulation of Gene_expression of Lpar1 42 0.61 31 20.71
89 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
90 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
91 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
92 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
93 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19
94 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
95 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
96 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
97 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
98 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
99 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
100 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
101 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
102 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
103 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
104 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
105 INT16624 Localization of Grin1 38 0.79 8.46 17.15
106 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
107 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
108 INT48055 Gene_expression of Grm1 27 0.78 14.29 17.01
109 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
110 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
111 INT48690 Localization of Grip2 33 0.61 6.13 16.81
112 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
113 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
114 INT49263 Binding of Grip2 31 0.41 9.86 16.38
115 INT153913 Positive_regulation of Lpar1 31 0.70 33.5 16.14
116 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
117 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
118 INT86790 Gene_expression of P2rx6 34 0.74 14.04 15.92
119 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
120 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
121 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
122 INT91285 Negative_regulation of P2rx2 29 0.57 12.74 15.48
123 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4
124 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38
125 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
126 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
127 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
128 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
129 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
130 INT94650 Gene_expression of Grm5 32 0.77 11.26 14.82
131 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
132 INT54052 Gene_expression of App 33 0.78 25.08 14.7
133 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
134 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
135 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
136 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
137 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
138 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
139 INT49538 Binding of Gria1 22 0.47 2.66 13.35
140 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
141 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
142 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
143 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
144 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75
145 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
146 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
147 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
148 INT29745 Binding of APP 47 0.48 26.49 12.4
149 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
150 INT112103 Binding of Grin1 28 0.48 4.21 12.08
151 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
152 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98
153 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
154 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
155 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
156 INT100919 Positive_regulation of Grm1 21 0.70 7.82 11.55
157 INT107522 Regulation of Grm5 9 0.44 6.42 11.46
158 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
159 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
160 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23
161 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
162 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
163 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
164 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
165 INT48912 Localization of NOS1 52 0.77 24.14 10.92
166 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
167 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
168 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78
169 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
170 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
171 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
172 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
173 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
174 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
175 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42
176 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
177 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
178 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3
179 INT5476 Regulation of Gabbr1 21 0.45 4.01 10.26
180 INT98329 Gene_expression of P2RX4 23 0.75 13.13 10.25
181 INT8072 Localization of Gria1 17 0.75 2.62 10.04
182 INT115614 Binding of Gria2 25 0.43 8.97 9.91
183 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
184 INT6356 Binding of Gabbr1 30 0.48 4.62 9.82
185 INT82769 Positive_regulation of Grm1 20 0.00 7.78 9.82
186 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
187 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
188 INT112428 Positive_regulation of Gene_expression of P2rx4 12 0.68 12.67 9.57
189 INT105304 Negative_regulation of Gene_expression of P2rx2 11 0.28 11.07 9.53
190 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
191 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
192 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
193 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47
194 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
195 INT41569 Regulation of APP 32 0.62 17.15 9.4
196 INT168991 Negative_regulation of P2rx4 9 0.43 12.77 9.39
197 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
198 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
199 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
200 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
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