GO:0043201

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Name response to leucine
Categary Process
Go Slim No
Go Link GO:0043201
Unique Molecular Interactions 27
Total Molecular Interactions 33
Total Single Events 254
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to leucine. They are ordered first by their pain relevance and then by number of times they were reported for response to leucine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
2 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
3 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11
4 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
5 INT205204 LPA Positive_regulation of Positive_regulation of Pik3c3 1 0.02 0.22 0.09
6 INT92584 Negative_regulation of PIK3C3 Negative_regulation of Gene_expression of PTGER2 1 0.01 0.46 0.07
7 INT313886 RPS6KB1 Positive_regulation of Gene_expression of XRCC1 1 0.01 0.8 0.05
8 INT150048 Ins1 Positive_regulation of Rps6kb1 2 0.23 0.83 0.04
9 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04
10 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04
11 INT228679 Binding of Rps6kb1 and Fig4 1 0.08 0.08 0.04
12 INT257868 Agt Positive_regulation of Rps6kb1 1 0.10 0.37 0.04
13 INT273117 Trh Positive_regulation of Rps6kb1 1 0.01 0.09 0.04
14 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
15 INT253412 ATIC Negative_regulation of Rps6kb1 1 0.02 0 0.03
16 INT284311 RPS6KB1 Positive_regulation of Phosphorylation of IRS1 1 0.18 0.24 0
17 INT246799 Pik3c3 Positive_regulation of Negative_regulation of Ogg1 1 0.04 0 0
18 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
19 INT246789 Pik3c3 Regulation of Tsc2 1 0.02 0.34 0
20 INT49943 Binding of Th and Pdx1 1 0.02 0.17 0
21 INT253380 Il6 Positive_regulation of Phosphorylation of Rps6kb1 1 0.29 0.07 0
22 INT253364 Lep Positive_regulation of Rps6kb1 1 0.30 0.08 0
23 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
24 INT246802 Pik3c3 Positive_regulation of Positive_regulation of Akt1 1 0.04 0 0
25 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
26 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
27 INT289527 Lep Regulation of Rps6kb1 1 0.10 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to leucine. They are ordered first by their pain relevance and then by number of times they were reported in response to leucine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
2 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
3 INT94572 Negative_regulation of Pik3c3 5 0.13 1.37 1.41
4 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
5 INT148027 Localization of Pik3c3 1 0.24 0.34 1.17
6 INT150942 Regulation of Pik3c3 2 0.18 0.96 0.94
7 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
8 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
9 INT112465 Binding of Rps6kb1 3 0.25 1.26 0.69
10 INT205200 Positive_regulation of Pik3c3 7 0.08 2.76 0.51
11 INT263820 Phosphorylation of RPS6KB1 6 0.52 1.43 0.42
12 INT90876 Negative_regulation of RPS6KB1 2 0.47 1.29 0.36
13 INT122996 Positive_regulation of Phosphorylation of Rps6kb1 9 0.58 1.53 0.34
14 INT156399 Regulation of Pdx1 1 0.00 0.96 0.33
15 INT281599 Localization of Rps6kb1 2 0.59 0.61 0.28
16 INT49942 Positive_regulation of Pdx1 5 0.02 1.24 0.26
17 INT281588 Negative_regulation of Localization of Rps6kb1 2 0.33 0.16 0.22
18 INT222130 Gene_expression of Pik3c3 3 0.12 0.62 0.21
19 INT276186 Negative_regulation of Gene_expression of Pik3c3 1 0.07 0.3 0.21
20 INT270722 Regulation of Positive_regulation of RPS6KB1 2 0.49 1.07 0.19
21 INT228901 Positive_regulation of RPS6KB1 5 0.55 2.44 0.18
22 INT92586 Negative_regulation of PIK3C3 2 0.03 0.73 0.18
23 INT257862 Negative_regulation of Positive_regulation of Rps6kb1 3 0.38 1.24 0.13
24 INT46335 Regulation of Rps6kb1 8 0.40 2.39 0.11
25 INT351430 Binding of PIK3C3 1 0.01 0 0.11
26 INT228902 Gene_expression of RPS6KB1 5 0.75 2.32 0.1
27 INT123875 Localization of Pdx1 1 0.80 0.28 0.09
28 INT349555 Positive_regulation of Localization of Rps6kb1 1 0.39 0.45 0.09
29 INT70606 Positive_regulation of Positive_regulation of Pdx1 1 0.02 0.4 0.09
30 INT122998 Positive_regulation of Gene_expression of Rps6kb1 2 0.60 0.62 0.08
31 INT284331 Positive_regulation of Phosphorylation of RPS6KB1 5 0.32 0.7 0.05
32 INT263818 Negative_regulation of Phosphorylation of RPS6KB1 1 0.01 0.43 0.05
33 INT257851 Regulation of Phosphorylation of Rps6kb1 1 0.40 0.95 0.03
34 INT97829 Gene_expression of Pdx1 7 0.32 1.14 0
35 INT228900 Positive_regulation of Gene_expression of RPS6KB1 2 0.49 1.6 0
36 INT246778 Positive_regulation of Positive_regulation of Pik3c3 1 0.06 0 0
37 INT351115 Negative_regulation of Binding of RPS6KB1 1 0.34 0.29 0
38 INT289570 Positive_regulation of Regulation of Rps6kb1 1 0.24 0.06 0
39 INT351117 Binding of RPS6KB1 1 0.30 0.77 0
40 INT132735 Positive_regulation of Gene_expression of Pdx1 1 0.29 0 0
41 INT246766 Positive_regulation of Gene_expression of Pik3c3 1 0.04 0.32 0
42 INT253407 Negative_regulation of Gene_expression of Rps6kb1 1 0.29 0 0
43 INT49941 Negative_regulation of Pdx1 1 0.02 0.07 0
44 INT208050 Localization of PIK3C3 1 0.01 0.13 0
45 INT49938 Negative_regulation of Positive_regulation of Pdx1 1 0.02 0.07 0
46 INT351129 Regulation of RPS6KB1 1 0.36 0.15 0
47 INT208038 Regulation of PIK3C3 1 0.00 0.64 0
48 INT284330 Positive_regulation of Positive_regulation of RPS6KB1 1 0.23 0.24 0
49 INT49940 Positive_regulation of Negative_regulation of Pdx1 1 0.02 0.07 0
50 INT257856 Positive_regulation of Positive_regulation of Rps6kb1 1 0.61 0.64 0
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