GO:0043204

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Name perikaryon
Categary Component
Go Slim No
Go Link GO:0043204
Unique Molecular Interactions 2484
Total Molecular Interactions 3624
Total Single Events 31469
Pain Genes Associated 104

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for perikaryon. They are ordered first by their pain relevance and then by number of times they were reported for perikaryon. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
3 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15
4 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
5 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
6 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
7 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
8 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
9 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
10 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
11 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
12 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
13 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47
14 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
15 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
16 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
17 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
18 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
19 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
20 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
21 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
22 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
23 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
24 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
25 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
26 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
27 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
28 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
29 INT73071 Binding of Cpe and Insrr 3 0.01 0.33 3.38
30 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
31 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
32 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
33 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
34 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
35 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
36 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08
37 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
38 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
39 INT28235 Binding of Cck and Gast 5 0.38 0.73 2.96
40 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91
41 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
42 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
43 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
44 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
45 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
46 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
47 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
48 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7
49 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
50 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
51 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
52 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
53 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
54 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
55 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
56 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
57 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57
58 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55
59 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
60 INT104218 SCD Positive_regulation of CNR2 1 0.01 2.67 2.54
61 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
62 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
63 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
64 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41
65 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
66 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
67 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
68 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
69 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
70 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34
71 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
72 INT14781 Cck Regulation of Gast 3 0.38 0.28 2.3
73 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
74 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 0.46 0 2.23
75 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
76 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
77 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
78 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
79 INT45376 Binding of Cpe and Mme 1 0.07 0.32 2.13
80 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
81 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
82 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
83 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
84 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
85 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
86 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
87 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
88 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
89 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
90 INT35502 Ghrh Positive_regulation of Localization of Gnrhr 7 0.57 0.18 2
91 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
92 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
93 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
94 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
95 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
96 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
97 INT69556 Slc7a11 Regulation of Cpe 2 0.06 0.46 1.95
98 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
99 INT73072 Negative_regulation of Binding of Cpe and Insrr 1 0.00 0 1.94
100 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
101 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
102 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
103 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
104 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
105 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
106 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
107 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
108 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
109 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
110 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
111 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
112 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
113 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
114 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
115 INT82867 Cck Regulation of Localization of Pgc 1 0.05 0 1.83
116 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
117 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
118 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
119 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
120 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
121 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
122 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
123 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
124 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
125 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
126 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
127 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
128 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
129 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
130 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
131 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
132 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
133 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
134 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
135 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
136 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
137 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
138 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
139 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
140 INT30743 Cck Regulation of Localization of Acot1 1 0.02 0 1.64
141 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
142 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
143 INT67966 Cck Positive_regulation of Adarb1 2 0.03 0 1.63
144 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
145 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
146 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
147 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
148 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
149 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
150 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
151 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
152 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
153 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
154 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
155 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57
156 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
157 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
158 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
159 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
160 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
161 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
162 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
163 INT40887 Penk Regulation of Th 1 0.04 0 1.53
164 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
165 INT42001 Cck Regulation of Vip 1 0.28 0 1.51
166 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
167 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
168 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
169 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
170 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
171 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
172 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47
173 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
174 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46
175 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
176 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
177 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
178 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
179 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
180 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
181 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
182 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
183 INT111760 Dio1 Positive_regulation of Binding of Cpe 1 0.04 0.34 1.44
184 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
185 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 0.01 0.33 1.43
186 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
187 INT111756 Dio1 Positive_regulation of Cpe 1 0.04 0.34 1.42
188 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
189 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
190 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
191 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
192 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
193 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
194 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
195 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
196 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
197 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
198 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
199 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
200 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for perikaryon. They are ordered first by their pain relevance and then by number of times they were reported in perikaryon. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
2 INT287 Localization of Cck 518 0.81 86.84 364.04
3 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
4 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41
5 INT3948 Regulation of Cck 291 0.62 58.07 255.88
6 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92
7 INT1562 Localization of Crh 499 0.81 126.74 236.68
8 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
9 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
10 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
11 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
12 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78
13 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
14 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
15 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
16 INT2366 Binding of Cck 192 0.48 30.64 163.46
17 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
18 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
19 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
20 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
21 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
22 INT7327 Regulation of Th 164 0.62 29.67 110.14
23 INT1898 Regulation of Crh 220 0.62 61.33 102.64
24 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
25 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25
26 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
27 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
28 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67
29 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
30 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
31 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
32 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
33 INT5095 Localization of Ghrh 185 0.81 28.09 62.08
34 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
35 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
36 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
37 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
38 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83
39 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08
40 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
41 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
42 INT1487 Regulation of Cpe 68 0.62 10.24 52.91
43 INT249 Localization of GHRH 215 0.80 78.02 51.87
44 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22
45 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14
46 INT2463 Localization of CCK 101 0.81 37.54 47.59
47 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
48 INT6544 Negative_regulation of Localization of Cck 67 0.59 8.05 47.23
49 INT5025 Positive_regulation of Gene_expression of Cck 63 0.70 10.96 47.11
50 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67
51 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
52 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
53 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
54 INT5214 Localization of Cpe 49 0.73 13.3 44.36
55 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
56 INT350 Localization of Th 79 0.80 10.26 41.17
57 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52
58 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
59 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
60 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
61 INT7824 Regulation of Cck 39 0.62 5.31 39.28
62 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
63 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
64 INT30817 Gene_expression of Th 142 0.76 33.56 38.12
65 INT12159 Transcription of Cck 46 0.72 9.36 37.58
66 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
67 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
68 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37
69 INT103172 Gene_expression of Slc12a5 81 0.77 39.45 36.22
70 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
71 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
72 INT13501 Binding of Drd2 65 0.48 23.76 35.6
73 INT7326 Transcription of Th 83 0.72 13.5 35.33
74 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21
75 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
76 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68
77 INT2699 Binding of Cpe 40 0.48 7.07 33.64
78 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
79 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
80 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
81 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
82 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
83 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
84 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09
85 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
86 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
87 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
88 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6
89 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
90 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21
91 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
92 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
93 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
94 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
95 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
96 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
97 INT16879 Binding of Crh 72 0.48 21.65 28.43
98 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
99 INT21379 Transcription of Crh 65 0.72 15.64 27.92
100 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
101 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
102 INT37296 Binding of Esr1 117 0.43 62.51 27.33
103 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
104 INT2408 Regulation of CCK 37 0.61 10.01 26.66
105 INT76621 Positive_regulation of Cnr2 32 0.69 17.77 26.57
106 INT7832 Localization of Cck 39 0.81 6.81 26.54
107 INT20462 Binding of ESR1 210 0.44 102.7 26.34
108 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
109 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
110 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
111 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
112 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99
113 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92
114 INT12484 Binding of Drd2 45 0.48 15.17 24.72
115 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
116 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95
117 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
118 INT7827 Binding of Cck 32 0.48 4.66 23.73
119 INT250 Regulation of GHRH 65 0.61 17.46 23.19
120 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
121 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
122 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
123 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
124 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
125 INT2911 Positive_regulation of Glul 36 0.70 11.09 22.07
126 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
127 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
128 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
129 INT103169 Negative_regulation of Slc12a5 38 0.58 27.75 20.81
130 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74
131 INT49774 Binding of DRD2 48 0.48 17.42 20.73
132 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
133 INT1156 Binding of CCK 27 0.48 8.71 20.58
134 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18
135 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
136 INT4841 Localization of Npff 26 0.80 4.36 19.91
137 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
138 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
139 INT8075 Localization of Crh 64 0.81 25.41 19.45
140 INT9128 Regulation of Gene_expression of Cck 27 0.62 6.55 19.45
141 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
142 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05
143 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
144 INT10286 Positive_regulation of Positive_regulation of Cck 20 0.70 4.05 18.46
145 INT9179 Positive_regulation of Localization of Ghrh 42 0.70 7.05 18.1
146 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
147 INT16155 Positive_regulation of Npff 25 0.70 6.21 17.58
148 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
149 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
150 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
151 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
152 INT219 Negative_regulation of Th 55 0.59 20.88 17.09
153 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
154 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
155 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
156 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51
157 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
158 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
159 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
160 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
161 INT24241 Phosphorylation of Th 35 0.81 8.69 16.06
162 INT13716 Positive_regulation of TH 33 0.68 19.11 16
163 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
164 INT92354 Localization of ESR1 77 0.75 33.04 15.51
165 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
166 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
167 INT1154 Negative_regulation of CCK 24 0.59 9.3 15.32
168 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
169 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
170 INT24798 Negative_regulation of Glul 52 0.55 27.25 15.17
171 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
172 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
173 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
174 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
175 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
176 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
177 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45
178 INT103170 Negative_regulation of Gene_expression of Slc12a5 26 0.58 17.25 14.4
179 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33
180 INT81495 Positive_regulation of CNR2 28 0.67 14.62 14.27
181 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
182 INT46582 Binding of Npff 20 0.48 1.49 13.99
183 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
184 INT17938 Binding of Cpe 28 0.48 11.17 13.62
185 INT4842 Regulation of Npff 13 0.54 4.59 13.62
186 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
187 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44
188 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
189 INT2038 Localization of Esr1 104 0.79 40.12 13.27
190 INT7585 Regulation of Crh 24 0.58 9.88 12.97
191 INT22003 Negative_regulation of Cpe 25 0.58 6.23 12.94
192 INT7852 Negative_regulation of Gene_expression of Cck 15 0.59 2.02 12.85
193 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
194 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
195 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51
196 INT18539 Gene_expression of Pnmt 33 0.78 3.08 12.47
197 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
198 INT5959 Protein_catabolism of Cpe 17 0.90 0.98 12.43
199 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
200 INT83601 Binding of CNR2 30 0.47 7.79 12.37
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