GO:0043206

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Name fibril organization
Categary Process
Go Slim No
Go Link GO:0043206
Unique Molecular Interactions 66
Total Molecular Interactions 76
Total Single Events 734
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fibril organization. They are ordered first by their pain relevance and then by number of times they were reported for fibril organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
3 INT282712 Binding of MUC5AC and Csf2 1 0.01 2.63 1.07
4 INT132166 PSG7 Positive_regulation of Muc5ac 1 0.00 0 0.73
5 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52
6 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
7 INT132171 PSG7 Positive_regulation of Localization of Muc5ac 1 0.00 0 0.39
8 INT132172 PSG7 Positive_regulation of Gene_expression of Muc5ac 1 0.00 0 0.34
9 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
10 INT179838 Col3a1 Regulation of Negative_regulation of Il11 1 0.21 0 0.29
11 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23
12 INT128986 Binding of CST3 and Phdlc1 1 0.01 1.96 0.22
13 INT285639 Col3a1 Regulation of Tnfrsf12a 1 0.19 0.16 0.22
14 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
15 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
16 INT318211 MUC5AC Positive_regulation of Muc4 1 0.17 1.12 0.17
17 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17
18 INT274168 Egf Positive_regulation of Gene_expression of Muc5ac 1 0.01 2.11 0.17
19 INT318185 MUC5AC Positive_regulation of Gene_expression of MMP3 1 0.09 0.86 0.13
20 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
21 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
22 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
23 INT318192 MUC5AC Negative_regulation of Gene_expression of VEGFA 1 0.20 0.98 0.1
24 INT318210 MUC5AC Negative_regulation of Phosphorylation of Flt1 1 0.07 0.98 0.09
25 INT294608 Binding of Serpinh1 and Col5a1 1 0.03 0.45 0.09
26 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05
27 INT207760 Fkbp1a Regulation of MSMB 1 0.12 0.69 0.04
28 INT318186 MUC5AC Positive_regulation of Gene_expression of VEGFA 1 0.22 1.01 0.04
29 INT188903 MUC5AC Positive_regulation of LDHA 1 0.00 1.2 0.04
30 INT179840 Binding of Col3a1 and Sparc 1 0.25 0 0.04
31 INT336752 Sparc Regulation of Regulation of Ilk 1 0.30 0.71 0.03
32 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
33 INT318190 Negative_regulation of MUC5AC Negative_regulation of Gene_expression of VEGFA 1 0.23 1.06 0.03
34 INT318187 Binding of INCENP and MUC5AC 1 0.00 1.03 0.03
35 INT132220 Muc5ac Regulation of Gene_expression of KRT7 1 0.01 0.18 0
36 INT129874 Binding of CST3 and CTSS 1 0.42 2.45 0
37 INT165187 Positive_regulation of Binding of CST3 and IL18 1 0.03 0.28 0
38 INT282879 Binding of MUC5AC and RHCE 1 0.00 0.36 0
39 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
40 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
41 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
42 INT225873 Ilk Positive_regulation of AKT1 1 0.00 0.07 0
43 INT316811 Negative_regulation of Col1a2 Negative_regulation of Col3a1 1 0.33 0.07 0
44 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0
45 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0
46 INT324305 Binding of CST3 and UMOD 1 0.05 3.22 0
47 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
48 INT265234 Binding of FKBP1A and SGCG 1 0.03 0.35 0
49 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
50 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
51 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0
52 INT145556 Binding of CST3 and TNNI3 1 0.25 0.11 0
53 INT324309 Binding of CST3 and GATM 1 0.00 1.6 0
54 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
55 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0
56 INT165189 Binding of CST3 and IL18 1 0.02 0.28 0
57 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0
58 INT282882 Binding of MUC1 and MUC5AC 1 0.15 0.56 0
59 INT132221 Muc5ac Regulation of KRT7 1 0.01 0.18 0
60 INT316821 Col1a2 Negative_regulation of Col3a1 1 0.33 0.07 0
61 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
62 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
63 INT353619 Positive_regulation of Mapk8 Positive_regulation of Gene_expression of Muc5ac 1 0.51 0.3 0
64 INT347297 ILK Regulation of Gene_expression of AKT1 1 0.21 0.62 0
65 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0
66 INT324308 Binding of CST3 and SHROOM3 1 0.04 1.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for fibril organization. They are ordered first by their pain relevance and then by number of times they were reported in fibril organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18
2 INT677 Positive_regulation of CST3 20 0.67 17.47 6
3 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
4 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
5 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32
6 INT152552 Gene_expression of Muc5ac 24 0.73 19.44 4
7 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
8 INT36032 Gene_expression of Col3a1 23 0.72 10.55 3.18
9 INT21076 Negative_regulation of Muc5ac 8 0.42 2.48 2.78
10 INT124862 Gene_expression of Col5a1 4 0.17 2.05 2.32
11 INT640 Regulation of CST3 9 0.60 4.04 2.26
12 INT69181 Positive_regulation of Col3a1 10 0.33 5.54 1.91
13 INT4489 Positive_regulation of Muc5ac 5 0.66 5.39 1.91
14 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
15 INT111575 Gene_expression of Muc5ac 15 0.78 7.97 1.84
16 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
17 INT60975 Localization of CST3 6 0.78 2.4 1.58
18 INT71847 Positive_regulation of Positive_regulation of Col3a1 2 0.33 0.61 1.39
19 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38
20 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36
21 INT124861 Positive_regulation of Col5a1 2 0.09 0.75 1.27
22 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22
23 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
24 INT173004 Transcription of MUC5AC 2 0.56 1.33 1.18
25 INT98595 Regulation of ILK 6 0.62 3.84 1.16
26 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14
27 INT36064 Binding of CST3 14 0.47 16.38 1.12
28 INT219108 Negative_regulation of Gene_expression of MUC5AC 11 0.31 9.74 1.08
29 INT13696 Regulation of COL3A1 2 0.45 2.97 0.95
30 INT173014 Positive_regulation of Gene_expression of MUC5AC 10 0.45 4.82 0.94
31 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
32 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91
33 INT111568 Transcription of Muc5ac 1 0.53 0.5 0.75
34 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7
35 INT104305 Binding of COL3A1 2 0.35 3.45 0.68
36 INT109603 Positive_regulation of Localization of CST3 1 0.45 0.61 0.67
37 INT125709 Positive_regulation of Gene_expression of Col3a1 7 0.27 5.17 0.65
38 INT111566 Regulation of Transcription of Muc5ac 1 0.27 0.43 0.65
39 INT22556 Positive_regulation of Gene_expression of COL3A1 5 0.37 4.25 0.64
40 INT11890 Protein_catabolism of COL3A1 2 0.77 2.41 0.64
41 INT124858 Negative_regulation of Positive_regulation of Col5a1 1 0.01 0.75 0.64
42 INT215183 Positive_regulation of MUC5AC 4 0.45 2.78 0.6
43 INT222716 Negative_regulation of Transcription of MUC5AC 1 0.42 0.6 0.59
44 INT197250 Localization of Muc5ac 7 0.71 4.83 0.55
45 INT98590 Negative_regulation of Positive_regulation of ILK 1 0.43 1.17 0.55
46 INT138429 Negative_regulation of Gene_expression of Col3a1 3 0.17 2.51 0.54
47 INT98592 Gene_expression of ILK 6 0.78 5.23 0.53
48 INT111574 Localization of Muc5ac 2 0.80 0.1 0.53
49 INT209517 Positive_regulation of Gene_expression of Muc5ac 5 0.57 8.26 0.5
50 INT98594 Positive_regulation of ILK 3 0.70 1.74 0.49
51 INT92684 Positive_regulation of Col3a1 5 0.56 1.79 0.45
52 INT125708 Negative_regulation of Col3a1 2 0.16 1.37 0.42
53 INT111571 Regulation of Gene_expression of Muc5ac 1 0.45 0.28 0.42
54 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
55 INT236948 Positive_regulation of Gene_expression of Col5a1 1 0.10 1.15 0.41
56 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
57 INT169628 Binding of SNCA 4 0.47 3.53 0.36
58 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34
59 INT222715 Positive_regulation of Transcription of MUC5AC 1 0.45 0.35 0.34
60 INT207065 Localization of Fkbp1a 1 0.36 0.82 0.33
61 INT131134 Regulation of Col5a1 1 0.06 0 0.32
62 INT109604 Negative_regulation of Localization of CST3 1 0.41 0.31 0.31
63 INT343973 Localization of SNCA 1 0.63 0.07 0.3
64 INT157605 Localization of COL3A1 3 0.80 0.55 0.29
65 INT179809 Regulation of Col3a1 2 0.25 0.1 0.29
66 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28
67 INT202802 Regulation of Fkbp1a 4 0.26 0.96 0.28
68 INT98593 Positive_regulation of Positive_regulation of ILK 1 0.50 0.58 0.28
69 INT209527 Regulation of Muc5ac 4 0.51 2.17 0.25
70 INT179798 Regulation of Gene_expression of Col3a1 2 0.22 0.57 0.25
71 INT292362 Negative_regulation of Gene_expression of Col3a1 1 0.10 1.01 0.25
72 INT98597 Positive_regulation of Gene_expression of ILK 4 0.70 3.08 0.23
73 INT130888 Regulation of Muc5ac 1 0.09 0.92 0.23
74 INT115873 Negative_regulation of Col5a1 1 0.06 0 0.22
75 INT212536 Negative_regulation of COL3A1 2 0.57 3.53 0.21
76 INT20608 Positive_regulation of Regulation of CST3 1 0.01 1.23 0.21
77 INT111570 Positive_regulation of Gene_expression of Muc5ac 1 0.50 0.14 0.21
78 INT22560 Positive_regulation of COL3A1 3 0.23 1.16 0.2
79 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19
80 INT98591 Positive_regulation of Regulation of ILK 1 0.47 0.7 0.18
81 INT22559 Regulation of Gene_expression of COL3A1 1 0.13 0.99 0.17
82 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
83 INT267616 Positive_regulation of Positive_regulation of MUC5AC 1 0.14 1.15 0.16
84 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
85 INT241037 Regulation of Col3a1 2 0.05 1.94 0.14
86 INT142657 Regulation of Gene_expression of Col3a1 2 0.15 1.6 0.14
87 INT142656 Transcription of Col3a1 3 0.37 0.82 0.13
88 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13
89 INT111572 Positive_regulation of Transcription of Muc5ac 1 0.47 0.08 0.12
90 INT111569 Negative_regulation of Gene_expression of Muc5ac 1 0.59 0.07 0.1
91 INT318205 Regulation of Negative_regulation of MUC5AC 1 0.19 0.44 0.09
92 INT314778 Regulation of Binding of CST3 1 0.26 1.5 0.09
93 INT678 Regulation of Negative_regulation of CST3 1 0.39 0.09 0.09
94 INT299319 Localization of FKBP1A 1 0.44 0 0.09
95 INT41924 Phosphorylation of CST3 1 0.57 0.23 0.09
96 INT247892 Positive_regulation of Localization of MUC5AC 1 0.28 1.51 0.09
97 INT344765 Negative_regulation of Positive_regulation of MUC5AC 1 0.27 0.44 0.08
98 INT353618 Transcription of Muc5ac 1 0.68 0.48 0.08
99 INT353612 Positive_regulation of Transcription of Muc5ac 1 0.44 0.48 0.08
100 INT353614 Regulation of Gene_expression of Muc5ac 1 0.58 0.95 0.08
101 INT353610 Regulation of Transcription of Muc5ac 1 0.58 0.48 0.08
102 INT39981 Positive_regulation of Binding of CST3 1 0.43 0.71 0.08
103 INT353615 Positive_regulation of Positive_regulation of Muc5ac 1 0.44 0.48 0.07
104 INT299313 Positive_regulation of Gene_expression of FKBP1A 1 0.29 0 0.05
105 INT324011 Negative_regulation of Muc5ac 1 0.20 0 0.04
106 INT179793 Binding of Col3a1 1 0.29 0 0.04
107 INT255522 Transcription of COL3A1 1 0.07 0.09 0.03
108 INT255537 Positive_regulation of Positive_regulation of COL3A1 1 0.05 0.09 0.03
109 INT336745 Regulation of Ilk 1 0.33 0.7 0.03
110 INT288241 Regulation of Gene_expression of CST3 1 0.44 0.28 0.03
111 INT179799 Negative_regulation of Col3a1 1 0.47 0 0.03
112 INT257448 Negative_regulation of Localization of MUC5AC 2 0.35 2.57 0
113 INT329612 Positive_regulation of Gene_expression of Col3a1 1 0.17 0.32 0
114 INT353617 Negative_regulation of Gene_expression of Muc5ac 1 0.41 0.6 0
115 INT209522 Binding of Muc5ac 1 0.45 0.14 0
116 INT347313 Binding of ILK 1 0.22 0.12 0
117 INT130135 Regulation of Localization of CST3 1 0.26 0 0
118 INT179819 Localization of Col3a1 1 0.64 0 0
119 INT347317 Localization of ILK 1 0.45 0 0
120 INT342934 Negative_regulation of Transcription of Col3a1 1 0.10 0.06 0
121 INT198452 Regulation of Binding of MUC5AC 1 0.15 0.33 0
122 INT347314 Regulation of Gene_expression of ILK 1 0.27 1.15 0
123 INT328632 Regulation of Gene_expression of MUC5AC 1 0.25 2.46 0
124 INT347307 Regulation of Binding of ILK 1 0.27 0.12 0
125 INT179811 Transcription of Col3a1 1 0.55 0.18 0
126 INT314777 Negative_regulation of Gene_expression of CST3 1 0.41 1.32 0
127 INT179789 Negative_regulation of Transcription of Col3a1 1 0.34 0.18 0
128 INT179834 Regulation of Transcription of Col3a1 1 0.36 0 0
129 INT198449 Positive_regulation of Negative_regulation of MUC5AC 1 0.17 0.26 0
130 INT318207 Negative_regulation of Negative_regulation of MUC5AC 1 0.34 0.75 0
131 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
132 INT324333 Transcription of CST3 1 0.67 0.2 0
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