GO:0043218

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Name compact myelin
Categary Component
Go Slim No
Go Link GO:0043218
Unique Molecular Interactions 43
Total Molecular Interactions 70
Total Single Events 567
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for compact myelin. They are ordered first by their pain relevance and then by number of times they were reported for compact myelin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49083 Mbp Positive_regulation of Eae1 1 0.02 2.96 1.71
2 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
3 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7
4 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
5 INT48304 Positive_regulation of MBP Positive_regulation of PLP1 1 0.10 0.97 0.64
6 INT48303 MBP Positive_regulation of PLP1 1 0.10 0.97 0.64
7 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61
8 INT62055 Mbp Positive_regulation of Lta 1 0.07 1.4 0.51
9 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
10 INT128944 Binding of Mbp and Mog 1 0.08 0.8 0.43
11 INT72348 Mbp Positive_regulation of Localization of PRSS1 1 0.01 0.22 0.41
12 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
13 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27
14 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27
15 INT238263 pma Positive_regulation of Gene_expression of Cd59 1 0.02 0.57 0.26
16 INT318620 Mog Regulation of Mbp 1 0.05 0.85 0.23
17 INT261384 Nsdhl Negative_regulation of Gene_expression of Mbp 1 0.01 1.43 0.14
18 INT96589 Mbp Regulation of S100B 1 0.34 0.97 0.13
19 INT312839 Egr2 Regulation of Gene_expression of Mbp 1 0.32 0.16 0.09
20 INT312844 Pou3f1 Regulation of Gene_expression of Pmp22 1 0.27 0.16 0.09
21 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09
22 INT312845 Pou3f1 Regulation of Gene_expression of Mbp 1 0.25 0.16 0.09
23 INT307665 Binding of Mpz and Pmp22 1 0.34 0.39 0.08
24 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08
25 INT249890 Binding of Mbp and Gpr17 1 0.11 0.09 0.08
26 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08
27 INT307664 Binding of Pmp22 and LOC689781 1 0.03 0.39 0.08
28 INT302530 Cpz Regulation of Negative_regulation of Mbp 1 0.22 0.1 0.07
29 INT302528 Hal Regulation of Negative_regulation of Mbp 1 0.16 0.1 0.07
30 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05
31 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
32 INT249426 Mbp Positive_regulation of Stx1a 1 0.10 0.11 0
33 INT257662 Binding of Mbp and Nphs1 1 0.11 0 0
34 INT249402 Binding of Mbp and Napa 1 0.17 0 0
35 INT32195 Itga7 Negative_regulation of Mbp 1 0.04 0.32 0
36 INT249401 Mbp Positive_regulation of Snap25 1 0.17 0.11 0
37 INT249408 Mbp Positive_regulation of Localization of Stx1a 1 0.11 0.33 0
38 INT249405 Binding of Mbp and Stx1a 1 0.11 0 0
39 INT249419 Mbp Positive_regulation of Localization of Snap25 1 0.17 0.33 0
40 INT249425 Binding of Mbp and Snap25 1 0.16 0 0
41 INT249407 Mbp Positive_regulation of Localization of Vamp2 1 0.13 0.11 0
42 INT249428 Mbp Negative_regulation of Binding of Napa 1 0.18 0 0
43 INT249422 Binding of Mbp and Vamp2 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for compact myelin. They are ordered first by their pain relevance and then by number of times they were reported in compact myelin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7580 Positive_regulation of Mbp 54 0.70 23.37 17.14
2 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11
3 INT7465 Negative_regulation of Mbp 53 0.58 19.12 13.27
4 INT4929 Binding of Mbp 25 0.48 18.01 9.41
5 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79
6 INT7464 Regulation of Mbp 25 0.62 6.62 6.43
7 INT14486 Localization of Mbp 23 0.74 11.24 6.14
8 INT48308 Binding of PLP1 7 0.48 9.59 6.09
9 INT48307 Positive_regulation of PLP1 5 0.66 8.42 5.09
10 INT48246 Gene_expression of PLP1 18 0.64 10.33 4.73
11 INT83623 Gene_expression of Cd59 7 0.76 7.35 4.7
12 INT78203 Gene_expression of PMP22 12 0.63 7.49 3.58
13 INT83737 Phosphorylation of Mbp 4 0.81 1.63 3.48
14 INT39884 Negative_regulation of Mbp 23 0.56 11.93 3.21
15 INT84021 Regulation of Mbp 8 0.57 6.79 3.09
16 INT15555 Localization of PLP1 6 0.60 3.35 2.75
17 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5
18 INT83622 Positive_regulation of Gene_expression of Cd59 4 0.49 3.77 2.35
19 INT14907 Negative_regulation of Positive_regulation of Mbp 4 0.40 0.75 2.32
20 INT62054 Transcription of Mbp 5 0.69 4.83 2.06
21 INT73239 Negative_regulation of Gene_expression of Mbp 6 0.46 5.65 1.96
22 INT67253 Gene_expression of Pmp22 4 0.33 6.48 1.79
23 INT231373 Negative_regulation of Pmp22 1 0.26 2.98 1.75
24 INT146387 Positive_regulation of Regulation of Mbp 1 0.43 0.25 1.71
25 INT14908 Positive_regulation of Positive_regulation of Mbp 4 0.42 0.85 1.47
26 INT83736 Regulation of Phosphorylation of Mbp 2 0.53 0.47 1.22
27 INT11771 Positive_regulation of Mbp 7 0.38 2.98 1.1
28 INT231379 Negative_regulation of Negative_regulation of Pmp22 1 0.26 1.72 1.09
29 INT83842 Positive_regulation of Gene_expression of Mbp 4 0.31 1.68 1.08
30 INT28849 Positive_regulation of Negative_regulation of Mbp 2 0.41 1.07 1.06
31 INT83738 Positive_regulation of Phosphorylation of Mbp 1 0.69 0 0.94
32 INT117254 Regulation of Gene_expression of PMP22 2 0.37 0.81 0.93
33 INT148293 Positive_regulation of Gene_expression of Pmp22 1 0.30 1.58 0.92
34 INT210276 Positive_regulation of Gene_expression of PMP22 3 0.46 1.58 0.88
35 INT83624 Positive_regulation of Cd59 2 0.49 1.41 0.82
36 INT94300 Negative_regulation of Gene_expression of Mbp 6 0.44 1.79 0.7
37 INT48306 Positive_regulation of Positive_regulation of PLP1 1 0.42 0.97 0.64
38 INT149155 Positive_regulation of Pmp22 1 0.15 0.08 0.62
39 INT149154 Positive_regulation of Gene_expression of Pmp22 1 0.15 0.08 0.62
40 INT355015 Protein_catabolism of Mbp 1 0.21 2.47 0.61
41 INT206530 Protein_catabolism of Mbp 3 0.79 0.92 0.5
42 INT135750 Positive_regulation of Transcription of Mbp 1 0.49 0 0.5
43 INT81550 Binding of Pmp22 4 0.35 4.2 0.49
44 INT27115 Binding of Mbp 8 0.31 3.01 0.48
45 INT215924 Regulation of Regulation of Mbp 1 0.17 0.8 0.48
46 INT135835 Positive_regulation of Gene_expression of PLP1 1 0.21 2.44 0.41
47 INT94304 Negative_regulation of Gene_expression of PLP1 2 0.20 1.02 0.36
48 INT94305 Negative_regulation of PLP1 1 0.03 4.28 0.35
49 INT153495 Binding of Pmp22 3 0.37 2.51 0.34
50 INT183394 Localization of Mbp 8 0.54 3.17 0.3
51 INT83775 Negative_regulation of Phosphorylation of Mbp 1 0.32 0.14 0.28
52 INT153496 Negative_regulation of Pmp22 2 0.42 3.34 0.26
53 INT160768 Negative_regulation of Cd59 2 0.36 1.12 0.26
54 INT78227 Positive_regulation of Gene_expression of Mbp 3 0.43 2.54 0.25
55 INT238251 Transcription of Cd59 1 0.30 0.19 0.18
56 INT81551 Negative_regulation of Gene_expression of Pmp22 2 0.11 4.03 0.15
57 INT141326 Positive_regulation of Binding of Mbp 1 0.00 0.94 0.15
58 INT238252 Negative_regulation of Gene_expression of Cd59 1 0.24 0.26 0.13
59 INT14547 Regulation of Negative_regulation of Mbp 1 0.24 0 0.13
60 INT27308 Negative_regulation of Localization of Mbp 1 0.41 0.08 0.12
61 INT238254 Positive_regulation of Positive_regulation of Cd59 1 0.28 0.34 0.11
62 INT137123 Regulation of Gene_expression of Mbp 3 0.25 0.7 0.1
63 INT27309 Negative_regulation of Negative_regulation of Mbp 2 0.57 0.3 0.09
64 INT139170 Negative_regulation of Gene_expression of Pmp22 1 0.37 0.83 0.09
65 INT160767 Regulation of Cd59 1 0.37 0.93 0.08
66 INT51444 Regulation of PMP22 2 0.44 1.39 0.07
67 INT206882 Regulation of PLP1 1 0.13 0.84 0.04
68 INT245657 Phosphorylation of Mbp 1 0.62 0.26 0.04
69 INT169666 Localization of Pmp22 1 0.81 0.49 0.03
70 INT81553 Binding of PMP22 2 0.03 2.13 0
71 INT252396 Transcription of PLP1 1 0.03 0.05 0
72 INT210275 Positive_regulation of PMP22 1 0.55 0.52 0
73 INT210279 Negative_regulation of Gene_expression of PMP22 1 0.34 0.3 0
74 INT307660 Positive_regulation of Pmp22 1 0.42 0.06 0
75 INT245662 Negative_regulation of Negative_regulation of Mbp 1 0.32 0.21 0
76 INT343056 Transcription of Mbp 1 0.33 0 0
77 INT334622 Negative_regulation of Regulation of Mbp 1 0.35 0.94 0
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