GO:0043219

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Name lateral loop
Categary Component
Go Slim No
Go Link GO:0043219
Unique Molecular Interactions 104
Total Molecular Interactions 173
Total Single Events 1743
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lateral loop. They are ordered first by their pain relevance and then by number of times they were reported for lateral loop. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
2 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
3 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
4 INT338044 F2 Positive_regulation of Pard3 1 0.08 0.38 0.4
5 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
6 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
7 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
8 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
9 INT144434 Gene_expression of Erbb2 Positive_regulation of ras 1 0.16 0.6 0.28
10 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
11 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
12 INT144433 Gene_expression of Erbb2 Positive_regulation of Positive_regulation of Mapk3 1 0.41 0.56 0.21
13 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
14 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18
15 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17
16 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
17 INT115610 Binding of ERBB2 and KLF1 1 0.02 2.12 0.17
18 INT118127 Binding of STXBP3 and Stx4 1 0.01 0.24 0.15
19 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
20 INT106994 PARD3 Positive_regulation of PAR4 1 0.21 0.28 0.14
21 INT107006 PARD3 Positive_regulation of SPG21 1 0.24 0.29 0.14
22 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13
23 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
24 INT338041 F2r Positive_regulation of Pard3 1 0.15 0.05 0.11
25 INT338048 F2rl3 Positive_regulation of Pard3 1 0.11 0.05 0.11
26 INT341826 Binding of ERBB2 and TNC 1 0.18 0.63 0.09
27 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09
28 INT257665 Binding of Nphs1 and Pard3 1 0.39 0.67 0.09
29 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08
30 INT309904 Binding of ERBB2 and TXK 1 0.01 0.23 0.08
31 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
32 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
33 INT293813 ERBB2 Positive_regulation of Positive_regulation of AR 1 0.09 0.45 0.07
34 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07
35 INT339101 ERBB2 Positive_regulation of TGFA 1 0.33 0.68 0.06
36 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
37 INT339099 ERBB2 Positive_regulation of IGF2R 1 0.33 0.67 0.06
38 INT339105 ERBB2 Positive_regulation of EGFR 1 0.37 0.68 0.06
39 INT339110 ERBB2 Positive_regulation of GATA6 1 0.31 0.67 0.06
40 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04
41 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
42 INT213901 EGFR Positive_regulation of ERBB2 1 0.52 0.41 0.04
43 INT339112 Binding of ERBB2 and TAB2 1 0.00 0.05 0.04
44 INT213906 EGFR Positive_regulation of Gene_expression of ERBB2 1 0.52 0.42 0.04
45 INT234196 ERBB2 Positive_regulation of Negative_regulation of HSP90AA1 1 0.19 0.79 0.03
46 INT341847 ERBB2 Positive_regulation of Gene_expression of ESYT1 1 0.02 1.42 0.03
47 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0
48 INT115609 Binding of ERBB2 and SFRP5 3 0.15 1.83 0
49 INT294088 Binding of ERBB2 and ERBB4 2 0.13 0.88 0
50 INT294089 Negative_regulation of Binding of ERBB2 and ERBB4 1 0.08 0.6 0
51 INT315163 Erbb2 Negative_regulation of Akt1 1 0.17 0.83 0
52 INT115611 Binding of EDNRA and ERBB2 1 0.08 0.78 0
53 INT315161 Egfr Negative_regulation of Erbb2 1 0.36 0.83 0
54 INT266925 Regulation of Binding of EGFR and ERBB2 1 0.26 0.5 0
55 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
56 INT351602 TXK Positive_regulation of ERBB2 1 0.02 0.58 0
57 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
58 INT186603 Binding of ERBB2 and Ednra 1 0.02 0.53 0
59 INT339113 Binding of ASIP and ERBB2 1 0.00 0.64 0
60 INT339104 Binding of ERBB2 and GRB7 1 0.30 1.29 0
61 INT256988 Binding of Dlg1 and Rpe 1 0.06 0 0
62 INT186589 Binding of ERBB2 and SCFV 1 0.13 0.65 0
63 INT263737 Binding of Dlg1 and Neto1 1 0.07 0 0
64 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0
65 INT191099 Erbb2 Positive_regulation of Shc1 1 0.08 1.95 0
66 INT293807 Positive_regulation of Binding of ERBB2 and RORC 1 0.02 0.12 0
67 INT250667 KLF1 Regulation of ERBB2 1 0.00 1.16 0
68 INT293803 Negative_regulation of ERBB2 Negative_regulation of Gene_expression of AR 1 0.10 0 0
69 INT312318 Binding of Cdh1 and Regulation of Transcription of Prl 1 0.30 0.39 0
70 INT293493 Hsp90aa1 Regulation of Gene_expression of Erbb2 1 0.38 0.1 0
71 INT315166 Erbb2 Negative_regulation of Egfr 1 0.36 0.83 0
72 INT310042 Binding of Cdh1 and Lsr1 1 0.01 0.09 0
73 INT294090 Negative_regulation of Binding of EGFR and ERBB2 1 0.14 0.6 0
74 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0
75 INT293814 Negative_regulation of ERBB2 Negative_regulation of Gene_expression of GOPC 1 0.02 0 0
76 INT225266 Erbb2 Positive_regulation of Gene_expression of VEGFA 1 0.04 0.79 0
77 INT160861 Erbb2 Regulation of EGF 1 0.49 0.73 0
78 INT257666 Binding of Mgst1 and Pard3 1 0.05 0 0
79 INT338047 Binding of F2r and Pard3 1 0.11 0 0
80 INT277860 MUC4 Negative_regulation of ERBB2 1 0.19 0.29 0
81 INT315168 Erbb2 Negative_regulation of Mapk3 1 0.03 0.83 0
82 INT223583 TXK Negative_regulation of ERBB2 1 0.07 0.18 0
83 INT315170 Erbb2 Negative_regulation of PCNA 1 0.03 0.84 0
84 INT312316 Gene_expression of Cdh1 Negative_regulation of Prl 1 0.29 0 0
85 INT277864 Binding of ERBB2 and Ralbp1 1 0.28 0.57 0
86 INT339115 Binding of ERBB2 and PVT1 1 0.43 1.11 0
87 INT257664 Regulation of Binding of Nphs1 and Pard3 1 0.36 0 0
88 INT232558 Binding of Erbb2 and Esr1 1 0.24 0.59 0
89 INT351603 Binding of ERBB2 and KDR 1 0.13 0.55 0
90 INT293799 Binding of ERBB2 and RORC 1 0.02 0.12 0
91 INT256981 Binding of Dlg1 and Slc9a3r1 1 0.22 0 0
92 INT314691 ERBB2 Negative_regulation of TP53 1 0.28 1.23 0
93 INT294087 Negative_regulation of Binding of ERBB2 and ERBB3 1 0.08 0.6 0
94 INT339103 Binding of ERBB2 and TRPS1 1 0.39 0.3 0
95 INT339106 Binding of BCS1L and ERBB2 1 0.04 0.17 0
96 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
97 INT339114 Binding of ERBB2 and MYC 1 0.22 0.81 0
98 INT93173 Ttf1 Positive_regulation of Erbb2 1 0.05 0.07 0
99 INT277863 Binding of ERBB2 and Abcc3 1 0.01 0.28 0
100 INT310039 Binding of Cdh1 and Slc30a4 1 0.04 0.46 0
101 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
102 INT339120 Binding of ERBB2 and MIEN1 1 0.31 0.42 0
103 INT312317 Cdh1 Regulation of Transcription of Prl 1 0.41 0.39 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lateral loop. They are ordered first by their pain relevance and then by number of times they were reported in lateral loop. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
2 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
3 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
4 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
5 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
6 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
7 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86
8 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
9 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
10 INT52962 Binding of ERBB2 77 0.47 50.03 1.49
11 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48
12 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34
13 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
14 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
15 INT293487 Regulation of Gene_expression of Erbb2 4 0.61 3.4 1.06
16 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
17 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91
18 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
19 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84
20 INT71649 Localization of ERBB2 23 0.78 13.63 0.83
21 INT176588 Phosphorylation of ERBB2 27 0.78 16.37 0.81
22 INT81396 Regulation of Gene_expression of ERBB2 14 0.43 10.73 0.74
23 INT235069 Localization of Cdh1 9 0.74 3.81 0.71
24 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66
25 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57
26 INT202196 Transcription of Erbb2 3 0.69 3.87 0.51
27 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48
28 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42
29 INT199559 Binding of Erbb2 5 0.36 4.23 0.36
30 INT181756 Positive_regulation of Erbb2 6 0.46 4.12 0.28
31 INT319280 Positive_regulation of Dlg1 1 0.45 0.42 0.28
32 INT208930 Positive_regulation of Pard3 2 0.33 0.49 0.27
33 INT178191 Regulation of Erbb2 7 0.36 4.11 0.24
34 INT209224 Binding of Dlg1 3 0.13 0.22 0.23
35 INT234858 Binding of Cdh1 11 0.47 4.58 0.22
36 INT215000 Transcription of Cdh1 4 0.40 1.17 0.22
37 INT153075 Phosphorylation of Erbb2 5 0.73 2.06 0.19
38 INT153074 Negative_regulation of Phosphorylation of Erbb2 3 0.52 1.41 0.19
39 INT339167 Positive_regulation of Localization of ERBB2 2 0.49 1.49 0.17
40 INT181787 Transcription of ERBB2 13 0.71 10.03 0.16
41 INT229402 Positive_regulation of PARD3 1 0.11 0.8 0.11
42 INT314718 Negative_regulation of Localization of ERBB2 1 0.37 1.13 0.11
43 INT153073 Positive_regulation of Phosphorylation of Erbb2 1 0.39 0.47 0.1
44 INT296622 Positive_regulation of Gene_expression of Cdh1 3 0.52 2.24 0.09
45 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09
46 INT276619 Negative_regulation of Transcription of Cdh1 1 0.24 0.57 0.09
47 INT232550 Negative_regulation of Gene_expression of Erbb2 9 0.43 4.96 0.07
48 INT251364 Negative_regulation of Gene_expression of Cdh1 4 0.32 1.02 0.07
49 INT221674 Localization of Erbb2 2 0.38 1.28 0.07
50 INT256975 Binding of Dlg1 7 0.36 0 0.06
51 INT192961 Positive_regulation of Negative_regulation of ERBB2 2 0.64 3.53 0.06
52 INT213915 Negative_regulation of Positive_regulation of ERBB2 2 0.41 1.09 0.05
53 INT349912 Negative_regulation of Negative_regulation of Cdh1 1 0.42 1.04 0.05
54 INT212270 Regulation of Localization of ERBB2 1 0.42 0.45 0.05
55 INT189881 Binding of Cdh1 6 0.36 1.24 0.04
56 INT251361 Transcription of Cdh1 1 0.36 0 0.04
57 INT257639 Binding of Pard3 1 0.35 0.4 0.04
58 INT349906 Negative_regulation of Localization of Cdh1 1 0.42 0.37 0.04
59 INT266927 Positive_regulation of Transcription of ERBB2 2 0.46 2.5 0.03
60 INT234210 Regulation of Negative_regulation of ERBB2 1 0.25 0.5 0.03
61 INT265512 Negative_regulation of Binding of ERBB2 4 0.40 1.43 0
62 INT234204 Protein_catabolism of ERBB2 3 0.82 1.6 0
63 INT286987 Positive_regulation of Phosphorylation of ERBB2 2 0.23 0.91 0
64 INT279213 Positive_regulation of Binding of ERBB2 2 0.46 2.29 0
65 INT251359 Regulation of Cdh1 2 0.34 0.47 0
66 INT189878 Localization of Cdh1 2 0.56 0.34 0
67 INT251362 Regulation of Gene_expression of Cdh1 2 0.46 0.4 0
68 INT256961 Regulation of Gene_expression of Dlg1 1 0.33 0 0
69 INT232554 Negative_regulation of Transcription of Erbb2 1 0.42 1.16 0
70 INT256978 Positive_regulation of Dlg1 1 0.34 0 0
71 INT293491 Protein_catabolism of Erbb2 1 0.87 1.06 0
72 INT256952 Localization of Dlg1 1 0.55 0 0
73 INT189879 Positive_regulation of Binding of Cdh1 1 0.08 0.15 0
74 INT301987 Negative_regulation of Positive_regulation of Cdh1 1 0.07 1.28 0
75 INT312313 Protein_catabolism of Cdh1 1 0.75 0.21 0
76 INT277861 Positive_regulation of Positive_regulation of ERBB2 1 0.64 0.32 0
77 INT349911 Regulation of Negative_regulation of Cdh1 1 0.44 0.23 0
78 INT324055 Regulation of Transcription of Cdh1 1 0.09 0.49 0
79 INT257646 Positive_regulation of Gene_expression of Pard3 1 0.51 0 0
80 INT189883 Negative_regulation of Localization of Cdh1 1 0.07 0.06 0
81 INT223291 Regulation of Transcription of ERBB2 1 0.25 0.21 0
82 INT341850 Positive_regulation of Protein_catabolism of ERBB2 1 0.42 0.97 0
83 INT293781 Regulation of Phosphorylation of ERBB2 1 0.24 0.13 0
84 INT296611 Positive_regulation of Negative_regulation of Cdh1 1 0.11 0.78 0
85 INT310014 Phosphorylation of Cdh1 1 0.16 0.24 0
86 INT256974 Gene_expression of Dlg1 1 0.50 0.08 0
87 INT301989 Positive_regulation of Binding of Cdh1 1 0.08 0.42 0
88 INT349904 Regulation of Localization of Cdh1 1 0.44 0.05 0
89 INT257653 Negative_regulation of Binding of Pard3 1 0.32 0.07 0
90 INT213924 Regulation of Binding of ERBB2 1 0.43 0.46 0
91 INT263679 Transcription of Dlg1 1 0.12 0.07 0
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