GO:0043237

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Name laminin-1 binding
Categary Function
Go Slim No
Go Link GO:0043237
Unique Molecular Interactions 60
Total Molecular Interactions 83
Total Single Events 444
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for laminin-1 binding. They are ordered first by their pain relevance and then by number of times they were reported for laminin-1 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
2 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
3 INT179844 Nid1 Regulation of Negative_regulation of Il11 1 0.19 0 0.29
4 INT189670 CHKB Negative_regulation of Gene_expression of DAG1 1 0.11 0 0.24
5 INT335464 Binding of DAG1 and PRKCA 1 0.03 0 0.22
6 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
7 INT189563 Binding of SLIT2 and ROBO4 1 0.03 0.71 0.18
8 INT352763 Sms Regulation of Gene_expression of DAG1 1 0.08 0.64 0.11
9 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
10 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
11 INT352766 DAG1 Positive_regulation of Prkd1 1 0.15 0.38 0.07
12 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
13 INT140771 Binding of NTN4 and Unc5a 1 0.02 0.35 0.07
14 INT140770 Binding of NTN4 and Unc5a 1 0.01 0.35 0.07
15 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
16 INT352762 DAG1 Regulation of Sms 1 0.03 0.37 0.05
17 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
18 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
19 INT352764 DAG1 Positive_regulation of Sms 1 0.06 0.11 0.03
20 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
21 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
22 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
23 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
24 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
25 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
26 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
27 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
28 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
29 INT180854 Binding of FBLN2 and NID1 1 0.01 0.92 0
30 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
31 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
32 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
33 INT230762 Binding of DAG1 and Tbx15 1 0.00 0.21 0
34 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
35 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
36 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
37 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
38 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
39 INT180859 Binding of COL1A1 and NID1 1 0.01 0.9 0
40 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
41 INT180863 Binding of COL5A2 and NID1 1 0.00 0.91 0
42 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
43 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
44 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
45 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
46 INT352765 DAG1 Regulation of Localization of Prkd1 1 0.09 0.09 0
47 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
48 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
49 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for laminin-1 binding. They are ordered first by their pain relevance and then by number of times they were reported in laminin-1 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
2 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
3 INT173328 Positive_regulation of DAG1 6 0.31 1.74 1.36
4 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
5 INT189771 Gene_expression of DAG1 5 0.27 4.14 1.12
6 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
7 INT64044 Localization of DAG1 3 0.59 0.27 0.87
8 INT206484 Localization of Shh 2 0.75 1.14 0.46
9 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
10 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
11 INT284325 Positive_regulation of Gene_expression of DAG1 3 0.13 1.08 0.36
12 INT179813 Regulation of Nid1 1 0.33 0 0.29
13 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
14 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
15 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
16 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
17 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
18 INT196355 Protein_catabolism of NID1 1 0.11 0.39 0.16
19 INT196358 Positive_regulation of Localization of NID1 1 0.06 0.44 0.16
20 INT196356 Localization of NID1 1 0.09 0.44 0.16
21 INT196354 Negative_regulation of Localization of NID1 1 0.05 0.44 0.16
22 INT253190 Localization of Shh 2 0.77 1.06 0.13
23 INT140759 Binding of NTN4 1 0.19 1.57 0.13
24 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
25 INT189625 Binding of SLIT2 3 0.33 0.49 0.12
26 INT270442 Transcription of Shh 1 0.53 0.25 0.09
27 INT213515 Binding of Shh 8 0.37 1.92 0.08
28 INT270453 Regulation of Shh 1 0.27 0.83 0.08
29 INT205973 Binding of SHH 3 0.35 1.03 0.07
30 INT140758 Gene_expression of NTN4 1 0.31 0.29 0.07
31 INT179792 Gene_expression of Nid1 1 0.56 0.21 0.07
32 INT256862 Regulation of Shh 1 0.25 0 0.07
33 INT341884 Positive_regulation of Localization of DAG1 1 0.03 0.21 0.06
34 INT352747 Regulation of DAG1 1 0.16 0.99 0.05
35 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
36 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
37 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
38 INT179815 Positive_regulation of Gene_expression of Nid1 1 0.50 0 0.04
39 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
40 INT253181 Transcription of Shh 1 0.68 0.54 0.03
41 INT179829 Negative_regulation of Nid1 1 0.42 0 0.03
42 INT140751 Regulation of NTN4 1 0.11 0.32 0
43 INT352742 Regulation of Gene_expression of DAG1 1 0.12 0.14 0
44 INT213595 Localization of SLIT2 1 0.67 0.06 0
45 INT213593 Gene_expression of SLIT2 1 0.60 0 0
46 INT230759 Binding of DAG1 1 0.03 0.21 0
47 INT179801 Positive_regulation of Nid1 1 0.50 0.06 0
48 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
49 INT140748 Positive_regulation of NTN4 1 0.20 0.31 0
50 INT179825 Localization of Nid1 1 0.44 0 0
51 INT179804 Regulation of Transcription of Nid1 1 0.33 0 0
52 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
53 INT290929 Binding of Shh 1 0.31 0.1 0
54 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
55 INT179808 Transcription of Nid1 1 0.50 0 0
56 INT352733 Negative_regulation of Localization of DAG1 1 0.11 0.06 0
57 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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