GO:0043280

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Name positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Categary Process
Go Slim No
Go Link GO:0043280
Unique Molecular Interactions 571
Total Molecular Interactions 839
Total Single Events 4399
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
3 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72
4 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
5 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
6 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
7 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
8 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
9 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
10 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
11 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
12 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
13 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
14 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
15 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
16 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98
17 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
18 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
19 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
20 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
21 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
22 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
23 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
24 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
25 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
26 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
27 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
28 INT278812 PYCARD Positive_regulation of VTA1 1 0.09 0.11 0.71
29 INT338057 Positive_regulation of F2r Positive_regulation of Localization of Calca 1 0.05 0.28 0.71
30 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
31 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
32 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 0.02 0.06 0.67
33 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
34 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
35 INT120348 Negative_regulation of Binding of DES and MYC 1 0.06 0.18 0.58
36 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
37 INT120350 Binding of DES and MYC 1 0.05 0.17 0.58
38 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
39 INT167907 Binding of F2r and ITS 1 0.01 0.7 0.55
40 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
41 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
42 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
43 INT338038 Gopc Regulation of Gene_expression of F2r 1 0.08 0 0.52
44 INT338045 F2r Regulation of Localization of Calca 1 0.03 0.05 0.52
45 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
46 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
47 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
48 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
49 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
50 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49
51 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48
52 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
53 INT338083 Binding of LEFTY1 and PYCARD 1 0.02 0 0.46
54 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
55 INT316694 Binding of BLZF1 and Nlrp2 1 0.00 0.75 0.45
56 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44
57 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
58 INT228323 PYCARD Positive_regulation of FIG4 1 0.17 0 0.42
59 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
60 INT338059 Nrtn Positive_regulation of Gene_expression of F2r 1 0.12 0.45 0.41
61 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
62 INT209918 Positive_regulation of Nlrp3 Positive_regulation of Localization of Il1 1 0.42 1.06 0.4
63 INT156237 Binding of F2r and Tnfsf14 1 0.02 1.14 0.4
64 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
65 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
66 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
67 INT353332 Binding of F2r and Pawr 1 0.18 0.67 0.39
68 INT338085 Binding of PYCARD and GOPC 1 0.05 0 0.39
69 INT334533 Binding of Foxq1 and Ngf 1 0.05 0.8 0.38
70 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
71 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
72 INT278813 Binding of NOVA2 and PYCARD 1 0.13 0 0.38
73 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37
74 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
75 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
76 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
77 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
78 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
79 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
80 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
81 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
82 INT112619 Mapk9 Regulation of Il1b 1 0.16 1.11 0.36
83 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
84 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
85 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
86 INT156235 Tnfsf14 Positive_regulation of F2r 1 0.03 1.03 0.35
87 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
88 INT200352 Binding of Rest and Rcor2 1 0.16 0.44 0.34
89 INT239540 Binding of CXCR2 and MYC 1 0.15 0.09 0.33
90 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32
91 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
92 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
93 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
94 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
95 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
96 INT289178 Regulation of PYCARD Regulation of MFGE8 1 0.05 0 0.32
97 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31
98 INT289175 PYCARD Regulation of behavior 1 0.03 0 0.31
99 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
100 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31
101 INT29984 Bad Positive_regulation of Localization of Prl 1 0.15 0 0.3
102 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
103 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3
104 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3
105 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3
106 INT289179 PYCARD Regulation of TW 1 0.02 0 0.3
107 INT239537 CXCR2 Regulation of MYC 1 0.15 0.05 0.29
108 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
109 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
110 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
111 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28
112 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
113 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
114 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
115 INT219156 NLRP3 Positive_regulation of IL1B 1 0.01 1.03 0.27
116 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27
117 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27
118 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
119 INT219194 Nlrp3 Positive_regulation of IL1B 1 0.04 1.03 0.26
120 INT219193 Nlrp3 Positive_regulation of Positive_regulation of NLRP3 1 0.24 1.03 0.26
121 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
122 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
123 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26
124 INT305686 Binding of Gfap and F2r 1 0.01 0 0.25
125 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
126 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
127 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
128 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25
129 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25
130 INT191792 Binding of F2r and Serpinc1 1 0.00 3.74 0.24
131 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
132 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
133 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24
134 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24
135 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24
136 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24
137 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
138 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24
139 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24
140 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
141 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
142 INT292554 MAP3K5 Positive_regulation of MAPK8 1 0.08 0 0.23
143 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
144 INT253773 TNF Positive_regulation of Hmgb1 1 0.09 1.21 0.23
145 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
146 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
147 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23
148 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22
149 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22
150 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22
151 INT274584 Binding of PSTPIP1 and PYCARD 1 0.13 1.34 0.22
152 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
153 INT289174 PYCARD Positive_regulation of MFGE8 1 0.05 0 0.21
154 INT181765 WISP3 Regulation of Gene_expression of RHOC 1 0.49 1.46 0.21
155 INT258456 PYCARD Negative_regulation of Localization of Tms 1 0.02 0.05 0.21
156 INT97694 Ngf Negative_regulation of Gene_expression of REST 1 0.01 0.09 0.21
157 INT258455 Tms Negative_regulation of Localization of PYCARD 1 0.02 0.05 0.21
158 INT349668 Binding of HRH1 and PYCARD 1 0.00 0.37 0.21
159 INT338042 F2r Positive_regulation of Localization of Prkca 1 0.06 0.1 0.2
160 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2
161 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2
162 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
163 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2
164 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2
165 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2
166 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2
167 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19
168 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
169 INT159794 Tnf Positive_regulation of Mapk9 1 0.01 0.42 0.19
170 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
171 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
172 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
173 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
174 INT159793 Tnf Positive_regulation of Gene_expression of Mapk9 1 0.01 0.42 0.19
175 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
176 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
177 INT123664 F2R Positive_regulation of PAR4 1 0.03 0.51 0.19
178 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
179 INT323613 Il1 Regulation of Localization of Hmgb1 1 0.10 0.75 0.19
180 INT339336 Binding of NKX3-1 and TAC4 1 0.03 0.08 0.18
181 INT289176 PYCARD Regulation of Localization of MFGE8 1 0.05 0 0.18
182 INT195115 Gene_expression of Gopc Positive_regulation of Positive_regulation of F2r 1 0.17 1.67 0.18
183 INT289177 PYCARD Regulation of Gene_expression of TW 1 0.03 0 0.18
184 INT195114 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of F2r 1 0.38 1.67 0.18
185 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
186 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
187 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17
188 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17
189 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
190 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
191 INT344832 Hmgb1 Positive_regulation of Gene_expression of Nos2 1 0.12 0.82 0.17
192 INT278398 Hps5 Positive_regulation of Nlrp3 1 0.26 1.38 0.16
193 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16
194 INT23165 Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
195 INT207144 F2r Positive_regulation of Pawr 1 0.14 0.51 0.16
196 INT23164 Negative_regulation of Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
197 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
198 INT104797 Smarce1 Positive_regulation of REST 1 0.01 0.24 0.15
199 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
200 INT207117 Binding of VEGFA and F2r 1 0.02 0.56 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27
2 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
3 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
4 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36
5 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
6 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
7 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
8 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
9 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
10 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
11 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
12 INT97516 Binding of PYCARD 46 0.36 7.06 7.85
13 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
14 INT1766 Negative_regulation of PYCARD 25 0.37 6.54 6.76
15 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52
16 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47
17 INT137052 Positive_regulation of PYCARD 30 0.43 4.72 6.17
18 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
19 INT166765 Localization of PYCARD 21 0.70 3.89 5.66
20 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
21 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
22 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
23 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17
24 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74
25 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
26 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66
27 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55
28 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
29 INT36221 Positive_regulation of Nlrp3 25 0.68 19.7 4.5
30 INT133231 Regulation of PYCARD 18 0.39 5.02 4.44
31 INT99020 Gene_expression of Nlrp3 23 0.75 18.86 4.4
32 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
33 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
34 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
35 INT51654 Regulation of Bad 21 0.40 12.18 4.06
36 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
37 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
38 INT184288 Localization of HMGB1 20 0.61 14.5 3.84
39 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
40 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
41 INT104480 Phosphorylation of Mapk9 8 0.80 6.59 3.62
42 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57
43 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
44 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
45 INT20419 Negative_regulation of Gene_expression of MYC 19 0.57 9.7 3.29
46 INT46754 Localization of F2r 7 0.78 2.36 3.24
47 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
48 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
49 INT58433 Negative_regulation of F2r 9 0.59 2.77 3.08
50 INT3437 Negative_regulation of Bad 5 0.48 1.66 2.99
51 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95
52 INT199255 Binding of Rest 14 0.41 1.43 2.94
53 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
54 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
55 INT36886 Transcription of Myc 6 0.69 3.16 2.86
56 INT82653 Regulation of F2r 8 0.36 3.78 2.62
57 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
58 INT29983 Localization of Bad 5 0.28 4.44 2.52
59 INT184272 Binding of HMGB1 14 0.37 8.78 2.49
60 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
61 INT150339 Gene_expression of F2R 10 0.73 3.59 2.46
62 INT108333 Phosphorylation of BAD 43 0.68 33.77 2.45
63 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
64 INT82798 Regulation of MYC 19 0.60 12.06 2.31
65 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
66 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
67 INT107685 Phosphorylation of MYC 3 0.80 2.52 2.28
68 INT10612 Localization of NLRP3 13 0.78 8.91 2.27
69 INT82652 Negative_regulation of F2r 4 0.37 3.5 2.19
70 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
71 INT73476 Transcription of MYC 18 0.69 12.14 2.13
72 INT92260 Binding of Nlrp3 14 0.46 8.94 2.13
73 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
74 INT172874 Phosphorylation of Bad 31 0.80 27.46 2.07
75 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99
76 INT69702 Positive_regulation of PMAIP1 7 0.35 8.81 1.98
77 INT24453 Binding of NLRP3 18 0.48 13.7 1.93
78 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9
79 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
80 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
81 INT155110 Negative_regulation of Phosphorylation of MYC 1 0.57 1.61 1.83
82 INT43143 Binding of Bad 8 0.21 5.12 1.81
83 INT104478 Positive_regulation of Mapk9 5 0.67 5.56 1.81
84 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
85 INT104479 Negative_regulation of Mapk9 3 0.37 2.83 1.69
86 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66
87 INT93427 Negative_regulation of Bad 4 0.02 2.5 1.63
88 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6
89 INT142678 Positive_regulation of Phosphorylation of Mapk9 4 0.51 2.1 1.6
90 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58
91 INT126759 Negative_regulation of Nlrp3 5 0.41 2.95 1.58
92 INT156231 Binding of F2r 9 0.23 3.78 1.57
93 INT5855 Positive_regulation of Bad 12 0.61 12.26 1.56
94 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53
95 INT184271 Positive_regulation of Gene_expression of HMGB1 7 0.41 6.17 1.53
96 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52
97 INT119835 Positive_regulation of Gene_expression of BAD 6 0.44 7.66 1.51
98 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
99 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
100 INT142676 Phosphorylation of Mapk9 5 0.61 1.48 1.48
101 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
102 INT18495 Regulation of Bad 6 0.19 4.79 1.45
103 INT92685 Transcription of Ctgf 7 0.72 3.92 1.44
104 INT119830 Gene_expression of BAD 24 0.50 20.05 1.41
105 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
106 INT165005 Binding of REST 26 0.43 2.81 1.39
107 INT159784 Gene_expression of Mapk9 8 0.61 6.28 1.37
108 INT142679 Negative_regulation of Phosphorylation of Mapk9 1 0.17 0.51 1.37
109 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
110 INT116265 Binding of Myc 9 0.36 4.28 1.36
111 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36
112 INT90226 Gene_expression of Mapk9 3 0.65 1.94 1.34
113 INT154081 Negative_regulation of Localization of Bad 2 0.16 2.06 1.31
114 INT20418 Regulation of Gene_expression of MYC 6 0.60 4.4 1.29
115 INT117498 Regulation of Positive_regulation of F2r 1 0.18 0.91 1.24
116 INT228328 Positive_regulation of Gene_expression of PYCARD 7 0.34 0.27 1.23
117 INT98976 Regulation of F2r 7 0.60 0.71 1.22
118 INT267652 Negative_regulation of Gene_expression of PYCARD 6 0.37 2.35 1.22
119 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
120 INT338033 Localization of F2r 1 0.41 0.62 1.2
121 INT219168 Positive_regulation of Localization of HMGB1 5 0.36 4 1.16
122 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15
123 INT158565 Regulation of Ctgf 3 0.61 3.93 1.14
124 INT158563 Negative_regulation of Ctgf 6 0.56 4.31 1.12
125 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
126 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05
127 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
128 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04
129 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
130 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
131 INT108340 Negative_regulation of Phosphorylation of BAD 11 0.49 8.29 1.02
132 INT307280 Regulation of Gene_expression of PYCARD 2 0.39 0.27 1.02
133 INT105986 Positive_regulation of Transcription of Ctgf 2 0.69 2.43 1.01
134 INT180423 Positive_regulation of Gene_expression of Rhoa 7 0.40 6.22 0.98
135 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
136 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
137 INT278350 Regulation of Nlrp3 3 0.38 2.8 0.95
138 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
139 INT17894 Regulation of Myc 10 0.60 5.65 0.93
140 INT219135 Positive_regulation of Gene_expression of Nlrp3 4 0.49 3.52 0.93
141 INT190591 Positive_regulation of Rest 3 0.37 2.52 0.92
142 INT195105 Negative_regulation of Gene_expression of F2r 3 0.37 1.41 0.91
143 INT82795 Binding of MYC 16 0.47 6.1 0.9
144 INT164079 Regulation of Gene_expression of CTGF 4 0.44 2 0.9
145 INT159668 Positive_regulation of Bad 8 0.45 6.32 0.89
146 INT200255 Localization of Rest 1 0.68 0.14 0.86
147 INT108341 Positive_regulation of BAD 8 0.42 8.75 0.85
148 INT196583 Regulation of Phosphorylation of Mapk9 1 0.37 0.5 0.85
149 INT146195 Positive_regulation of Localization of Rhoa 4 0.45 2.67 0.84
150 INT133767 Transcription of Bad 2 0.57 1.72 0.84
151 INT104482 Positive_regulation of Phosphorylation of Mapk9 2 0.49 1.55 0.84
152 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
153 INT228326 Positive_regulation of Localization of PYCARD 3 0.41 0 0.8
154 INT231380 Negative_regulation of Phosphorylation of Rhoa 1 0.13 1.28 0.79
155 INT195099 Positive_regulation of Gene_expression of F2r 7 0.57 5.31 0.78
156 INT275180 Positive_regulation of Phosphorylation of Bad 4 0.40 3.79 0.77
157 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
158 INT353325 Positive_regulation of Localization of F2r 1 0.49 1.31 0.76
159 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
160 INT231369 Phosphorylation of Rhoa 1 0.25 1.22 0.73
161 INT201628 Positive_regulation of Gene_expression of Bad 12 0.68 13.86 0.72
162 INT104488 Negative_regulation of Phosphorylation of Mapk9 1 0.41 1.03 0.72
163 INT25663 Localization of PMAIP1 3 0.38 2.47 0.71
164 INT62192 Regulation of Localization of F2r 2 0.60 0.59 0.7
165 INT268557 Regulation of Regulation of MYC 1 0.44 0.86 0.69
166 INT153802 Positive_regulation of Localization of BAD 1 0.30 0.64 0.66
167 INT25664 Negative_regulation of Localization of PMAIP1 1 0.09 0.09 0.66
168 INT153799 Localization of BAD 1 0.45 0.63 0.66
169 INT331152 Positive_regulation of Localization of Bad 1 0.19 1.35 0.64
170 INT36742 Regulation of NLRP3 2 0.16 0 0.63
171 INT197832 Localization of MEN1 1 0.80 11.01 0.63
172 INT331150 Negative_regulation of Gene_expression of Bad 1 0.10 1.33 0.63
173 INT15981 Positive_regulation of Positive_regulation of NLRP3 2 0.44 1.02 0.62
174 INT138235 Positive_regulation of Pycard 2 0.33 1.66 0.62
175 INT207089 Regulation of Negative_regulation of F2r 1 0.17 1.49 0.62
176 INT353321 Regulation of Positive_regulation of F2r 1 0.60 0.6 0.62
177 INT164585 Regulation of PMAIP1 2 0.20 2.07 0.61
178 INT107686 Positive_regulation of Negative_regulation of MYC 2 0.49 1.59 0.6
179 INT123672 Positive_regulation of F2R 9 0.47 0.77 0.58
180 INT168448 Localization of Nlrp3 5 0.73 3.75 0.58
181 INT219136 Positive_regulation of Positive_regulation of Nlrp3 3 0.49 2.61 0.58
182 INT138239 Localization of Pycard 2 0.53 1.05 0.58
183 INT138238 Positive_regulation of Localization of Pycard 1 0.33 0.66 0.58
184 INT184277 Regulation of Localization of HMGB1 1 0.37 1.15 0.58
185 INT316940 Positive_regulation of Phosphorylation of Rhoa 1 0.41 0.41 0.58
186 INT316931 Phosphorylation of Rhoa 1 0.48 0.41 0.57
187 INT140368 Positive_regulation of Positive_regulation of Rhoa 3 0.69 0.2 0.56
188 INT104483 Positive_regulation of Positive_regulation of Mapk9 1 0.49 0.75 0.56
189 INT108339 Positive_regulation of Phosphorylation of BAD 6 0.58 3.95 0.55
190 INT180420 Negative_regulation of Gene_expression of Rhoa 3 0.37 1.65 0.55
191 INT150000 Positive_regulation of Positive_regulation of BAD 2 0.14 3.1 0.55
192 INT180422 Regulation of Gene_expression of Rhoa 2 0.39 0.6 0.55
193 INT104484 Regulation of Mapk9 1 0.12 0.73 0.55
194 INT200273 Negative_regulation of Rest 1 0.43 0.69 0.55
195 INT153634 Regulation of REST 4 0.48 1.42 0.54
196 INT191777 Binding of F2r 2 0.02 0.89 0.54
197 INT192946 Gene_expression of PMAIP1 2 0.27 1.77 0.52
198 INT164584 Positive_regulation of Positive_regulation of PMAIP1 1 0.20 0.9 0.52
199 INT338026 Regulation of Localization of F2r 1 0.25 0.05 0.52
200 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
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