GO:0043297

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Name apical junction assembly
Categary Process
Go Slim No
Go Link GO:0043297
Unique Molecular Interactions 125
Total Molecular Interactions 174
Total Single Events 944
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for apical junction assembly. They are ordered first by their pain relevance and then by number of times they were reported for apical junction assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
2 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
3 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
4 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
5 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
6 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
7 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
8 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
9 INT181765 WISP3 Regulation of Gene_expression of RHOC 1 0.49 1.46 0.21
10 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
11 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
12 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
13 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
14 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
15 INT180447 Binding of Rhoa and Car2 1 0.17 0.56 0.13
16 INT241454 Rgnef Positive_regulation of Positive_regulation of Rhoa 1 0.04 0.11 0.13
17 INT269572 MAPKAP1 Positive_regulation of RHOA 1 0.06 0 0.13
18 INT269548 ARHGEF17 Positive_regulation of RHOA 1 0.01 0 0.12
19 INT326387 Binding of PROC and Rhoa 1 0.00 0.59 0.12
20 INT241446 Rgnef Positive_regulation of Rhoa 1 0.04 0.1 0.12
21 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
22 INT180449 Rhoa Regulation of Positive_regulation of Car2 1 0.13 0 0.09
23 INT269593 MAPKAP1 Positive_regulation of Positive_regulation of RHOA 1 0.06 0 0.09
24 INT180443 Rhoa Regulation of Negative_regulation of Mlc1 1 0.04 0 0.09
25 INT109959 INS Positive_regulation of FBF1 1 0.27 0.24 0.09
26 INT141257 Binding of S100A8 and VCL 1 0.36 0.97 0.09
27 INT141256 S100A8 Positive_regulation of VCL 1 0.50 0.99 0.06
28 INT159851 Positive_regulation of RHOA Positive_regulation of Gene_expression of IL2 1 0.15 0.15 0.06
29 INT326377 Ezr Positive_regulation of Positive_regulation of Rhoa 1 0.05 0.16 0.06
30 INT141258 S100A8 Negative_regulation of VCL 1 0.43 0.99 0.06
31 INT326378 Binding of Rhoa and Ezr 1 0.04 0.17 0.06
32 INT183863 RHOC Positive_regulation of Gene_expression of MAPK1 1 0.25 0.26 0.05
33 INT326384 Slc9a3r2 Positive_regulation of Positive_regulation of Rhoa 1 0.03 0.16 0.05
34 INT183851 RHOC Positive_regulation of MAPK1 1 0.34 0.26 0.05
35 INT183859 RHOC Positive_regulation of IFI44 1 0.18 0.26 0.05
36 INT183850 RHOC Positive_regulation of Gene_expression of IFI44 1 0.13 0.26 0.05
37 INT353317 Edn1 Positive_regulation of RHOA 1 0.19 0.16 0.04
38 INT180438 Positive_regulation of Rhoa Positive_regulation of Car2 1 0.22 0.48 0.03
39 INT183858 Negative_regulation of RHOC Positive_regulation of MAPK1 1 0.26 0.17 0.03
40 INT241450 Binding of Rhoa and Dpysl3 1 0.02 0 0.03
41 INT288829 Binding of Rhoa and Rac1 2 0.21 1.88 0
42 INT326383 Binding of Rhoa and Gopc 2 0.04 0.89 0
43 INT254849 Negative_regulation of Rhoa Positive_regulation of Phosphorylation of Smad3 1 0.11 0.45 0
44 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
45 INT269586 Negative_regulation of TMPO Positive_regulation of RHOA 1 0.14 0 0
46 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0
47 INT180446 Rhoa Regulation of Gene_expression of Car2 1 0.21 0.17 0
48 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0
49 INT334472 Gopc Regulation of Positive_regulation of Rhoa 1 0.02 0.3 0
50 INT269547 PTGIR Regulation of Phosphorylation of RHOA 1 0.02 0 0
51 INT295706 PTGER2 Regulation of Regulation of RHOA 1 0.01 0.61 0
52 INT254851 C3 Negative_regulation of Rhoa 1 0.06 0 0
53 INT254848 Tgfb1 Negative_regulation of Rhoa 1 0.02 0 0
54 INT342432 Binding of Rhoa and Positive_regulation of Atp9a 1 0.20 0 0
55 INT334469 Gopc Regulation of Localization of Rhoa 1 0.02 0.3 0
56 INT269549 Regulation of GOPC Positive_regulation of RHOA 1 0.09 0 0
57 INT254854 Positive_regulation of C3 Negative_regulation of Rhoa 1 0.05 0 0
58 INT269581 PTGIR Regulation of RHOA 1 0.02 0 0
59 INT295714 PTGER2 Positive_regulation of RHOA 1 0.01 0.34 0
60 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
61 INT334473 PGGT1B Regulation of Localization of Rhoa 1 0.04 0.47 0
62 INT269571 Positive_regulation of GOPC Positive_regulation of RHOA 1 0.10 0 0
63 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
64 INT183897 Binding of RHOC and Racgap1 1 0.01 0.2 0
65 INT254865 Rhoa Positive_regulation of Fbrs 1 0.08 0.81 0
66 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
67 INT269555 GOPC Positive_regulation of RHOA 1 0.10 0 0
68 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
69 INT254864 Rhoa Positive_regulation of Egfl7 1 0.02 0.82 0
70 INT322843 Positive_regulation of PIK3CD Positive_regulation of Positive_regulation of RHOA 1 0.03 0 0
71 INT269564 MAPKAP1 Regulation of Positive_regulation of RHOA 1 0.03 0 0
72 INT269590 Positive_regulation of TMPO Positive_regulation of RHOA 1 0.16 0 0
73 INT269583 TMPO Positive_regulation of Gene_expression of RHOA 1 0.16 0.14 0
74 INT334468 Rhoa Regulation of Localization of Rac1 1 0.25 0.18 0
75 INT269574 Regulation of TMPO Positive_regulation of RHOA 1 0.20 0 0
76 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0
77 INT254853 Rhoa Positive_regulation of Rac1 1 0.10 0.81 0
78 INT269576 Negative_regulation of GOPC Positive_regulation of RHOA 1 0.08 0 0
79 INT180125 Rhoa Positive_regulation of Rock1 1 0.14 0 0
80 INT344318 PDPN Positive_regulation of Positive_regulation of RHOA 1 0.11 0.92 0
81 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
82 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
83 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
84 INT201741 Binding of Rhoa and Ngfr 1 0.01 1 0
85 INT180439 Rhoa Regulation of Gene_expression of Acot1 1 0.07 0.17 0
86 INT183855 Binding of RHOC and ARHGEF3 1 0.02 1.8 0
87 INT183854 Regulation of CAV1 Positive_regulation of RHOC 1 0.41 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for apical junction assembly. They are ordered first by their pain relevance and then by number of times they were reported in apical junction assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
2 INT24444 Regulation of FBF1 2 0.12 5.55 5.06
3 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
4 INT24441 Positive_regulation of FBF1 13 0.39 6.52 4.29
5 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
6 INT24445 Gene_expression of FBF1 2 0.35 2.73 3.63
7 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
8 INT24442 Negative_regulation of FBF1 5 0.36 3.38 3.17
9 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
10 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
11 INT24446 Positive_regulation of Gene_expression of FBF1 2 0.23 3.96 2.72
12 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
13 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
14 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
15 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
16 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
17 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
18 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
19 INT85348 Localization of RHOA 12 0.59 4.81 1.83
20 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72
21 INT354254 Negative_regulation of Regulation of FBF1 1 0.03 2.25 1.67
22 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
23 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36
24 INT142992 Phosphorylation of RHOA 3 0.80 0.87 1.28
25 INT128176 Regulation of RHOA 13 0.44 4.35 1.26
26 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
27 INT136817 Negative_regulation of Positive_regulation of RHOA 8 0.57 0 1.04
28 INT180423 Positive_regulation of Gene_expression of Rhoa 7 0.40 6.22 0.98
29 INT131824 Negative_regulation of RHOA 10 0.57 2.9 0.92
30 INT146195 Positive_regulation of Localization of Rhoa 4 0.45 2.67 0.84
31 INT111941 Regulation of Phosphorylation of VCL 1 0.27 0.66 0.8
32 INT111942 Positive_regulation of Phosphorylation of VCL 1 0.30 0.67 0.8
33 INT231380 Negative_regulation of Phosphorylation of Rhoa 1 0.13 1.28 0.79
34 INT173338 Positive_regulation of Localization of RHOA 2 0.14 1.52 0.76
35 INT85347 Negative_regulation of Localization of RHOA 1 0.31 0 0.74
36 INT231369 Phosphorylation of Rhoa 1 0.25 1.22 0.73
37 INT111601 Negative_regulation of Gene_expression of CTNNA1 1 0.24 0.58 0.58
38 INT316940 Positive_regulation of Phosphorylation of Rhoa 1 0.41 0.41 0.58
39 INT111609 Gene_expression of CTNNA1 3 0.46 3.2 0.57
40 INT316931 Phosphorylation of Rhoa 1 0.48 0.41 0.57
41 INT140368 Positive_regulation of Positive_regulation of Rhoa 3 0.69 0.2 0.56
42 INT180420 Negative_regulation of Gene_expression of Rhoa 3 0.37 1.65 0.55
43 INT180422 Regulation of Gene_expression of Rhoa 2 0.39 0.6 0.55
44 INT111606 Positive_regulation of CTNNA1 1 0.12 0.47 0.47
45 INT140373 Binding of Rhoa 3 0.48 0.28 0.45
46 INT354255 Negative_regulation of Gene_expression of FBF1 1 0.02 0.74 0.45
47 INT131851 Positive_regulation of RHOC 3 0.57 9.44 0.41
48 INT131849 Negative_regulation of RHOC 4 0.54 6.46 0.34
49 INT183879 Binding of RHOA 6 0.34 2.1 0.31
50 INT131822 Positive_regulation of Positive_regulation of RHOA 2 0.45 0.33 0.29
51 INT140371 Positive_regulation of Negative_regulation of Rhoa 1 0.46 0 0.26
52 INT109859 Localization of Rhoa 3 0.54 1.09 0.24
53 INT289343 Regulation of Gene_expression of Rhoa 1 0.13 0.28 0.23
54 INT140365 Negative_regulation of Protein_catabolism of Rhoa 1 0.43 0 0.23
55 INT140358 Negative_regulation of Positive_regulation of Rhoa 1 0.43 0 0.23
56 INT289342 Negative_regulation of Gene_expression of Rhoa 1 0.20 0.28 0.23
57 INT289353 Positive_regulation of Gene_expression of Rhoa 1 0.23 0.28 0.23
58 INT180415 Regulation of Rhoa 7 0.53 3.92 0.22
59 INT140359 Positive_regulation of Protein_catabolism of Rhoa 1 0.69 0 0.22
60 INT140369 Protein_catabolism of Rhoa 1 0.99 0 0.22
61 INT180418 Binding of Rhoa 16 0.32 7.05 0.2
62 INT354258 Localization of FBF1 1 0.05 0.23 0.18
63 INT140361 Regulation of Positive_regulation of Rhoa 1 0.45 0 0.17
64 INT131847 Negative_regulation of Gene_expression of RHOC 2 0.39 1.38 0.12
65 INT131852 Positive_regulation of Negative_regulation of RHOC 1 0.46 1.12 0.12
66 INT172526 Regulation of RHOC 2 0.51 4.7 0.1
67 INT269666 Regulation of Gene_expression of RHOA 1 0.32 0.38 0.1
68 INT282407 Transcription of Rhoa 1 0.15 0.52 0.1
69 INT109961 Positive_regulation of Positive_regulation of FBF1 1 0.14 0.25 0.08
70 INT109862 Negative_regulation of Localization of Rhoa 1 0.33 0.37 0.08
71 INT141261 Negative_regulation of VCL 1 0.45 0.95 0.07
72 INT148812 Localization of RHOC 2 0.62 1.75 0.05
73 INT126629 Negative_regulation of Transcription of Rhoa 1 0.33 0 0.05
74 INT263798 Gene_expression of VCL 1 0.18 1.14 0.05
75 INT180419 Regulation of Positive_regulation of Rhoa 2 0.39 0.9 0.04
76 INT269659 Negative_regulation of Gene_expression of RHOA 1 0.42 0.26 0.04
77 INT126630 Transcription of Rhoa 1 0.54 0 0.04
78 INT295675 Protein_catabolism of RHOA 2 0.24 0.21 0
79 INT183874 Negative_regulation of Positive_regulation of RHOC 1 0.35 0.18 0
80 INT322860 Regulation of Protein_catabolism of RHOA 1 0.08 0 0
81 INT269608 Regulation of Positive_regulation of RHOA 1 0.32 0.06 0
82 INT183884 Positive_regulation of Binding of RHOC 1 0.41 0.27 0
83 INT183891 Regulation of Positive_regulation of RHOC 1 0.22 0.37 0
84 INT212954 Positive_regulation of Negative_regulation of Rhoa 1 0.19 1.18 0
85 INT191647 Regulation of Regulation of Rhoa 1 0.13 0.32 0
86 INT183887 Binding of RHOC 1 0.40 3.01 0
87 INT355598 Negative_regulation of CTNNA1 1 0.04 1.06 0
88 INT269627 Regulation of Phosphorylation of RHOA 1 0.32 0 0
89 INT269597 Negative_regulation of Phosphorylation of RHOA 1 0.31 0 0
90 INT283878 Localization of VCL 1 0.19 1.12 0
91 INT269624 Positive_regulation of Phosphorylation of RHOA 1 0.36 0 0
92 INT183875 Positive_regulation of Positive_regulation of RHOC 1 0.38 0.73 0
93 INT334441 Regulation of Localization of Rhoa 1 0.33 0.88 0
94 INT307737 Binding of VCL 1 0.13 0.36 0
95 INT183872 Regulation of Gene_expression of RHOC 1 0.32 0.34 0
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