GO:0043304

From wiki-pain
Jump to: navigation, search
Name regulation of mast cell degranulation
Categary Process
Go Slim No
Go Link GO:0043304
Unique Molecular Interactions 67
Total Molecular Interactions 82
Total Single Events 420
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of mast cell degranulation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of mast cell degranulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
2 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
3 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
4 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
5 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
6 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
7 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
8 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
9 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
10 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
11 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
12 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
13 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
14 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
15 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
16 INT95469 P2ry6 Positive_regulation of Positive_regulation of Pdpk1 1 0.15 0 0.46
17 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
18 INT151184 Pdpk1 Positive_regulation of Trpv1 1 0.08 0 0.42
19 INT151183 Pdpk1 Positive_regulation of Phosphorylation of Trpv1 1 0.08 0 0.42
20 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
21 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36
22 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
23 INT222721 Binding of HTR1A and Pdpk1 1 0.00 0.35 0.33
24 INT18994 Negative_regulation of Pdpk1 Negative_regulation of Regulation of Cck 1 0.10 0 0.26
25 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2
26 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
27 INT58006 DYT10 Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.14 0.18
28 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
29 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
30 INT179849 Il11 Regulation of Positive_regulation of Pdpk1 1 0.05 0.07 0.17
31 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15
32 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
33 INT1233 Gcg Positive_regulation of Pdpk1 1 0.27 0 0.14
34 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
35 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
36 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12
37 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12
38 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
39 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
40 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
41 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
42 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
43 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08
44 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
45 INT352941 Pik3cb Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.21 0.06
46 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05
47 INT276211 Pdpk1 Regulation of Akt1 1 0.07 0.72 0.04
48 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
49 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
50 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
51 INT78615 Pdpk1 Regulation of Gene_expression of Penk 1 0.03 0 0
52 INT278388 Msu Positive_regulation of Phosphorylation of Lyn 1 0.17 0.12 0
53 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
54 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
55 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0
56 INT353435 Binding of Pdpk1 and Rock1 1 0.09 0.27 0
57 INT221622 Dpysl2 Positive_regulation of Fes 1 0.24 0 0
58 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0
59 INT200818 Akt1 Positive_regulation of Negative_regulation of Lyn 1 0.25 1.02 0
60 INT98235 Pde5a Negative_regulation of Pdpk1 1 0.00 0.32 0
61 INT221635 Dpysl2 Negative_regulation of Phosphorylation of Fes 1 0.20 0 0
62 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0
63 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of mast cell degranulation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of mast cell degranulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
2 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
3 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
4 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
5 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
6 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
7 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
8 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
9 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
10 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
11 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
12 INT47846 Negative_regulation of Localization of Pdpk1 2 0.33 1.12 2.75
13 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65
14 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
15 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84
16 INT104014 Negative_regulation of Phosphorylation of Pdpk1 2 0.23 0.59 1.72
17 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
18 INT67464 Positive_regulation of Negative_regulation of Pdpk1 1 0.19 0.15 1.41
19 INT118927 Positive_regulation of Phosphorylation of Pdpk1 2 0.04 0.76 1.38
20 INT221206 Phosphorylation of Pdpk1 3 0.53 0.13 1.25
21 INT104011 Transcription of Pdpk1 1 0.28 0 1.2
22 INT104012 Regulation of Transcription of Pdpk1 1 0.14 0 1.2
23 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19
24 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
25 INT68467 Regulation of Regulation of Pdpk1 1 0.05 0.09 0.96
26 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
27 INT149383 Binding of Lyn 1 0.36 1.14 0.91
28 INT221543 Binding of Fes 1 0.45 1.79 0.83
29 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
30 INT79249 Regulation of Negative_regulation of Pdpk1 1 0.03 0.09 0.57
31 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
32 INT98037 Negative_regulation of Negative_regulation of Pdpk1 1 0.05 0.26 0.52
33 INT236107 Binding of Pdpk1 2 0.26 1.38 0.39
34 INT236105 Negative_regulation of Binding of Pdpk1 1 0.30 1.22 0.39
35 INT179816 Positive_regulation of Pdpk1 4 0.31 0.36 0.35
36 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2
37 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2
38 INT221535 Regulation of Fes 1 0.25 0.19 0.19
39 INT221549 Localization of Fes 1 0.70 0.66 0.19
40 INT221532 Positive_regulation of Fes 1 0.47 0.59 0.19
41 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15
42 INT304452 Regulation of Lyn 1 0.17 0 0.15
43 INT221571 Negative_regulation of Fes 1 0.55 0.56 0.12
44 INT236109 Localization of Pdpk1 1 0.49 0.75 0.12
45 INT221577 Negative_regulation of Phosphorylation of Fes 1 0.40 0.37 0.12
46 INT221530 Negative_regulation of Binding of Fes 1 0.40 0.17 0.08
47 INT104656 Regulation of Phosphorylation of Pdpk1 1 0.05 1.74 0.07
48 INT120564 Gene_expression of Pdpk1 2 0.62 1.54 0.06
49 INT120565 Positive_regulation of Gene_expression of Pdpk1 1 0.40 1.26 0.06
50 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05
51 INT315847 Positive_regulation of Negative_regulation of Lyn 1 0.18 0.61 0.05
52 INT236706 Regulation of Pdpk1 1 0.12 0.38 0.04
53 INT221565 Regulation of Binding of Fes 1 0.42 0.05 0.03
54 INT331203 Positive_regulation of Binding of Pdpk1 1 0.15 0.17 0
55 INT221567 Transcription of Fes 1 0.64 0 0
56 INT278323 Positive_regulation of Phosphorylation of Lyn 1 0.22 0 0
57 INT278322 Negative_regulation of Localization of Lyn 1 0.20 0.11 0
58 INT221563 Positive_regulation of Localization of Fes 1 0.47 0.05 0
59 INT221524 Regulation of Localization of Fes 1 0.42 0.06 0
60 INT221523 Negative_regulation of Gene_expression of Fes 1 0.40 0 0
61 INT278356 Localization of Lyn 1 0.35 0.11 0
62 INT189989 Negative_regulation of Pdpk1 1 0.08 1.48 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox