GO:0043401

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Name steroid hormone mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0043401
Unique Molecular Interactions 1178
Total Molecular Interactions 1502
Total Single Events 18424
Pain Genes Associated 48

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for steroid hormone mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for steroid hormone mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
3 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
4 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
5 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
6 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
7 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
8 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
9 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
10 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
11 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
12 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
13 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
14 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
15 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
16 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
17 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92
18 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
19 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
20 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
21 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
22 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
23 INT291548 Binding of Gper and Sec22b 1 0.02 0.94 0.67
24 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
25 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
26 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
27 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
28 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
29 INT231027 LOC100366054 Negative_regulation of Gene_expression of Pgr 1 0.02 0 0.62
30 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 0.43 0.1 0.62
31 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
32 INT2686 Binding of Thra and SGSM3 1 0.36 0.1 0.61
33 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
34 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
35 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
36 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
37 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
38 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54
39 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
40 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53
41 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
42 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
43 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
44 INT130335 Binding of Mc4r and Nr3c2 1 0.06 1.87 0.5
45 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
46 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
47 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49
48 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47
49 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
50 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46
51 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
52 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44
53 INT321293 Binding of Nr1h4 and Nr0b2 1 0.18 0.31 0.43
54 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
55 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
56 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
57 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
58 INT49716 PCA Negative_regulation of Nr3c2 1 0.02 0 0.41
59 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4
60 INT238382 Il13 Positive_regulation of Gene_expression of Ppara 1 0.18 0.79 0.4
61 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
62 INT236110 Binding of Ppara and Olfm4 1 0.00 1.22 0.4
63 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
64 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38
65 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
66 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38
67 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
68 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38
69 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38
70 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
71 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38
72 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38
73 INT337890 Per1 Regulation of Nr2f2 1 0.08 0 0.37
74 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
75 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
76 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37
77 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
78 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37
79 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
80 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
81 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36
82 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
83 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35
84 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
85 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
86 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34
87 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33
88 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
89 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
90 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
91 INT291543 Binding of Dlat and Gper 1 0.15 0.37 0.33
92 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
93 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
94 INT253142 Positive_regulation of Nr1h2 Negative_regulation of Gene_expression of Mmp9 1 0.05 0.6 0.33
95 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
96 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
97 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
98 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32
99 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
100 INT336936 Binding of GSR and Nr3c2 1 0.06 2.29 0.31
101 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
102 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
103 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
104 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
105 INT209931 IL1B Positive_regulation of PPARA 1 0.32 0.62 0.31
106 INT336933 Binding of Nr3c2 and Ugcg 1 0.07 2.3 0.31
107 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
108 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
109 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
110 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29
111 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
112 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
113 INT209933 PPARA Regulation of Positive_regulation of IL1B 1 0.21 0.58 0.29
114 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29
115 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29
116 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29
117 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29
118 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29
119 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
120 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
121 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29
122 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29
123 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
124 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28
125 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
126 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
127 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
128 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28
129 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
130 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
131 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27
132 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27
133 INT101510 PPARA Regulation of IL6 1 0.31 0.53 0.27
134 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27
135 INT101508 PPARA Regulation of IL8 1 0.31 0.53 0.27
136 INT49717 PCA Regulation of Nr3c2 1 0.01 0 0.27
137 INT337884 Ins1 Negative_regulation of Gene_expression of Nr2f2 1 0.11 0.08 0.27
138 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
139 INT101509 PPARA Regulation of Gene_expression of IL8 1 0.31 0.53 0.27
140 INT337896 Ins1 Negative_regulation of Nr2f2 1 0.15 0.1 0.27
141 INT101511 PPARA Regulation of Gene_expression of IL6 1 0.31 0.53 0.27
142 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27
143 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
144 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
145 INT103280 PGR Negative_regulation of Positive_regulation of ATF4 1 0.02 0.31 0.26
146 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26
147 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26
148 INT245640 Nr3c2 Regulation of Positive_regulation of Hpse 1 0.08 0.66 0.26
149 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26
150 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26
151 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
152 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25
153 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25
154 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
155 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25
156 INT262180 Nr1h4 Regulation of Sult2a1 1 0.11 0.11 0.25
157 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
158 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25
159 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
160 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25
161 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
162 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
163 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
164 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25
165 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
166 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
167 INT138088 Ddc Regulation of Transcription of Nr4a1 1 0.02 0.16 0.24
168 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
169 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24
170 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
171 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
172 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24
173 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
174 INT298785 PPARA Positive_regulation of ACOX1 3 0.29 1.58 0.23
175 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23
176 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
177 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23
178 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
179 INT337892 Positive_regulation of Mc4r Positive_regulation of Gene_expression of Nr2f2 1 0.34 0 0.23
180 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
181 INT238383 Tlr4 Positive_regulation of Ppara 1 0.17 0.41 0.23
182 INT63193 POMC Positive_regulation of PGR 1 0.17 0.3 0.23
183 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 0.03 0.23 0.23
184 INT63199 INS Positive_regulation of PGR 1 0.11 0.3 0.23
185 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23
186 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
187 INT179229 Binding of GSR and NR3C2 1 0.03 0.37 0.23
188 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
189 INT229702 Binding of Ppara and Ros1 1 0.01 1.05 0.23
190 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
191 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
192 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22
193 INT63194 PTH Positive_regulation of PGR 1 0.25 0.29 0.22
194 INT35151 PLOD1 Regulation of PGR 1 0.09 0 0.21
195 INT35152 GH1 Regulation of PGR 1 0.08 0 0.21
196 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21
197 INT35156 FSHR Regulation of PGR 1 0.18 0 0.21
198 INT263339 Ptger2 Regulation of Ppara 1 0.09 0.44 0.21
199 INT262210 Negative_regulation of Nr1i2 Negative_regulation of Positive_regulation of Cyp3a11 1 0.31 0.4 0.2
200 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2

Single Events

The table below shows the top 100 pain related interactions that have been reported for steroid hormone mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in steroid hormone mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
2 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
3 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
4 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
5 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
6 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
7 INT122041 Binding of Ppara 308 0.48 189.17 51.48
8 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
9 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
10 INT103094 Binding of PPARA 308 0.47 177.26 34.75
11 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
12 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
13 INT37296 Binding of Esr1 117 0.43 62.51 27.33
14 INT20462 Binding of ESR1 210 0.44 102.7 26.34
15 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
16 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
17 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
18 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84
19 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
20 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
21 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
22 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
23 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
24 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
25 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
26 INT92354 Localization of ESR1 77 0.75 33.04 15.51
27 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
28 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
29 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
30 INT12321 Binding of Nr3c2 19 0.46 5.44 13.46
31 INT2038 Localization of Esr1 104 0.79 40.12 13.27
32 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
33 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79
34 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
35 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
36 INT194462 Localization of Ppara 94 0.78 68.33 12.09
37 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97
38 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
39 INT173159 Localization of PPARA 96 0.74 64.55 10.26
40 INT7577 Regulation of Nr3c2 16 0.56 7.7 10.1
41 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
42 INT125444 Gene_expression of Rora 5 0.75 3.05 8.97
43 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39
44 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
45 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
46 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
47 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
48 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
49 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83
50 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
51 INT12314 Negative_regulation of Nr3c2 16 0.56 14.82 6.72
52 INT170922 Binding of Ppara 59 0.45 28.45 6.7
53 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
54 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
55 INT96218 Positive_regulation of Pgr 17 0.68 5.23 6.57
56 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
57 INT67609 Binding of Pparg 17 0.46 9.53 6.06
58 INT129901 Gene_expression of Nr1i2 60 0.73 22.44 6.04
59 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96
60 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74
61 INT86023 Transcription of PPARA 60 0.66 25.8 5.7
62 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
63 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56
64 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
65 INT122038 Transcription of Ppara 35 0.71 20.5 5.12
66 INT170927 Negative_regulation of Ppara 27 0.54 13.58 5.12
67 INT181186 Binding of Rxra 78 0.35 14.93 4.87
68 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
69 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73
70 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67
71 INT337882 Gene_expression of Nr2f2 1 0.76 3.45 4.6
72 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
73 INT55552 Regulation of Gene_expression of Nr3c2 5 0.59 5.93 4.53
74 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41
75 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39
76 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
77 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
78 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
79 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84
80 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
81 INT20461 Binding of Esr1 34 0.48 9.58 3.66
82 INT121942 Binding of Nr1i2 2 0.45 15.69 3.66
83 INT114957 Positive_regulation of Transcription of PPARA 18 0.62 10.36 3.65
84 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
85 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
86 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
87 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33
88 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
89 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28
90 INT147522 Positive_regulation of Gene_expression of Ppara 28 0.47 15.82 3.18
91 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
92 INT114276 Gene_expression of Nr4a1 20 0.77 7.71 3.14
93 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
94 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
95 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
96 INT187618 Localization of Ppara 13 0.70 6.91 3.09
97 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
98 INT82913 Regulation of Ppara 15 0.61 10.66 3.03
99 INT7571 Transcription of Nr3c2 6 0.58 2.15 3.03
100 INT2897 Positive_regulation of Thra 20 0.45 5.17 3.01
101 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
102 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89
103 INT112758 Binding of Ppard 7 0.37 3.6 2.87
104 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85
105 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
106 INT321310 Positive_regulation of Nr1h4 1 0.49 1.75 2.75
107 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73
108 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72
109 INT190881 Positive_regulation of Rora 2 0.43 1.76 2.71
110 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
111 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68
112 INT136105 Regulation of Pgr 4 0.45 1.93 2.62
113 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58
114 INT147517 Negative_regulation of Gene_expression of Ppara 12 0.37 3.46 2.55
115 INT125442 Negative_regulation of Gene_expression of Rora 5 0.57 2.92 2.54
116 INT7574 Positive_regulation of Transcription of Nr3c2 4 0.54 1.26 2.52
117 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
118 INT110284 Negative_regulation of Positive_regulation of Nr3c2 4 0.53 2.08 2.48
119 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
120 INT169073 Positive_regulation of Nr1h4 8 0.47 2.44 2.45
121 INT197228 Positive_regulation of Gene_expression of Rora 1 0.05 0 2.43
122 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36
123 INT108796 Binding of ESR2 5 0.46 6.84 2.36
124 INT34830 Regulation of PGR 14 0.45 6.99 2.32
125 INT129902 Regulation of Nr1i2 16 0.58 6.3 2.31
126 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3
127 INT22605 Regulation of Pgr 22 0.62 7.1 2.26
128 INT178632 Regulation of Gene_expression of Pgr 11 0.35 1.56 2.26
129 INT83236 Localization of PGR 14 0.73 8.26 2.23
130 INT13267 Binding of Pgr 15 0.40 3.5 2.22
131 INT55365 Regulation of Binding of Nr3c2 2 0.56 0.85 2.2
132 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
133 INT169072 Gene_expression of Nr1h4 7 0.60 6.23 2.18
134 INT55364 Negative_regulation of Binding of Nr3c2 2 0.39 0.87 2.17
135 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14
136 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
137 INT68496 Binding of PGR 26 0.48 16.36 2.09
138 INT337864 Positive_regulation of Gene_expression of Nr2f2 1 0.68 0.48 2.07
139 INT135692 Localization of Nr3c2 7 0.77 4.14 1.98
140 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
141 INT109800 Binding of Esr2 8 0.42 1.79 1.93
142 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
143 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
144 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89
145 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88
146 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88
147 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
148 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87
149 INT168269 Negative_regulation of Positive_regulation of Ppara 3 0.38 0.57 1.87
150 INT90315 Positive_regulation of Gene_expression of Nr3c2 4 0.55 2 1.83
151 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74
152 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
153 INT96216 Negative_regulation of Positive_regulation of Pgr 2 0.37 0.74 1.72
154 INT81169 Localization of Nr4a2 1 0.68 0 1.71
155 INT153918 Binding of Esr2 3 0.33 2.56 1.7
156 INT314189 Positive_regulation of Phosphorylation of Nr5a1 1 0.02 2.16 1.7
157 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
158 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
159 INT30076 Negative_regulation of Esr2 1 0.01 0 1.63
160 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
161 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
162 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
163 INT114279 Positive_regulation of Nr4a1 9 0.59 3.37 1.59
164 INT314187 Phosphorylation of Nr5a1 1 0.04 1.96 1.59
165 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
166 INT132761 Negative_regulation of Pgr 6 0.50 3.07 1.58
167 INT50724 Positive_regulation of Positive_regulation of Nr4a2 2 0.49 0.17 1.58
168 INT262127 Negative_regulation of Gene_expression of Nr1i2 1 0.55 6.92 1.57
169 INT45711 Localization of Pgr 7 0.61 1.27 1.56
170 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
171 INT173198 Regulation of Binding of PPARA 17 0.43 9.58 1.47
172 INT67457 Binding of Rara 12 0.24 8.28 1.45
173 INT84888 Binding of PPARD 5 0.48 2.82 1.45
174 INT112963 Regulation of Positive_regulation of PPARA 8 0.44 5.29 1.43
175 INT96324 Negative_regulation of Gene_expression of Nr3c2 3 0.56 1.01 1.43
176 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
177 INT173162 Phosphorylation of PPARA 22 0.80 11.09 1.38
178 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
179 INT136981 Positive_regulation of Gene_expression of Nr1i2 2 0.65 3.63 1.34
180 INT122040 Positive_regulation of Transcription of Ppara 9 0.50 3.97 1.33
181 INT68500 Regulation of Ar 6 0.27 4.16 1.32
182 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28
183 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
184 INT2681 Binding of Thra 11 0.32 5.98 1.27
185 INT139356 Regulation of Nr1h2 2 0.43 2.95 1.27
186 INT158078 Gene_expression of Gper 7 0.67 1.13 1.26
187 INT8511 Localization of Esr1 6 0.80 3.27 1.26
188 INT245636 Regulation of Positive_regulation of Nr3c2 2 0.59 1.55 1.25
189 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
190 INT197167 Positive_regulation of Localization of Ppara 18 0.67 9.51 1.21
191 INT2682 Regulation of Thra 4 0.55 0.49 1.21
192 INT183635 Negative_regulation of Positive_regulation of Ppara 11 0.42 10 1.2
193 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
194 INT227548 Negative_regulation of Localization of Ppara 7 0.38 4.1 1.17
195 INT114272 Regulation of Gene_expression of Nr4a1 5 0.45 1.82 1.14
196 INT159162 Binding of Gper 2 0.48 1.69 1.12
197 INT262114 Negative_regulation of Nr1i2 1 0.55 4.72 1.12
198 INT52546 Gene_expression of NR3C2 10 0.65 1.09 1.1
199 INT19277 Gene_expression of Thra 4 0.58 0.68 1.1
200 INT321329 Positive_regulation of Positive_regulation of Nr1h4 1 0.35 0.43 1.07
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