GO:0043438

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Name acetoacetic acid metabolic process
Categary Process
Go Slim No
Go Link GO:0043438
Unique Molecular Interactions 23
Total Molecular Interactions 35
Total Single Events 290
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for acetoacetic acid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for acetoacetic acid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69874 POMC Negative_regulation of TYRP1 1 0.13 0 1.07
2 INT69871 ASIP Negative_regulation of TYRP1 1 0.36 0 1.07
3 INT30130 Binding of TYRP1 and Gast 1 0.06 0.09 0.63
4 INT293900 TYRP1 Regulation of IGKC 1 0.01 0.11 0.27
5 INT71643 Binding of HLA-A and TYRP1 1 0.24 0.36 0.26
6 INT323346 Positive_regulation of Tyrp1 Positive_regulation of Positive_regulation of Gpr35 1 0.11 0.76 0.21
7 INT313799 Binding of HLA-B and TYRP1 1 0.01 0.54 0.18
8 INT293901 Positive_regulation of TYRP1 Regulation of IGKC 1 0.02 0.06 0.15
9 INT162776 TYRP1 Regulation of Kcnq2 1 0.24 0.14 0.14
10 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
11 INT309724 Regulation of Binding of TYRP1 and TRPV4 1 0.01 0 0.09
12 INT309754 Binding of TYRP1 and TRPV4 1 0.02 0 0.09
13 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 0.00 0 0.09
14 INT94653 Tyrp1 Positive_regulation of Positive_regulation of Tyr 1 0.39 0 0.08
15 INT268087 Binding of Tyrp1 and Gpr35 1 0.02 0 0.08
16 INT313807 Binding of TYRP1 and YOD1 1 0.00 0.49 0.06
17 INT309726 Binding of CALM1 and TYRP1 1 0.00 0 0.05
18 INT309730 Binding of CALM3 and TYRP1 1 0.01 0 0.05
19 INT268085 Tdo2 Regulation of Gene_expression of Tyrp1 1 0.25 0.09 0.04
20 INT268084 Tdo2 Positive_regulation of Tyrp1 1 0.26 0.09 0.04
21 INT313805 Binding of TYRP1 and SPG16 1 0.00 0 0
22 INT313801 Binding of TYR and TYRP1 1 0.03 0 0
23 INT313797 Binding of MET and TYRP1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for acetoacetic acid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in acetoacetic acid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59
2 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84
3 INT49027 Gene_expression of TYRP1 35 0.75 9.81 6.06
4 INT68591 Regulation of TYRP1 14 0.44 3.93 5.05
5 INT142501 Transcription of Tyrp1 4 0.18 2.09 3.71
6 INT18073 Positive_regulation of TYRP1 11 0.67 1.98 3.36
7 INT83073 Negative_regulation of Tyrp1 10 0.23 4.4 2.65
8 INT30040 Negative_regulation of TYRP1 11 0.51 2.72 2.54
9 INT37341 Regulation of Tyrp1 4 0.29 4.53 2.42
10 INT30037 Binding of TYRP1 9 0.36 0.45 1.6
11 INT145177 Positive_regulation of Gene_expression of Tyrp1 5 0.30 3.31 1.46
12 INT62425 Regulation of Gene_expression of Tyrp1 7 0.29 1.44 1.41
13 INT323338 Positive_regulation of Positive_regulation of Tyrp1 2 0.13 1.53 1.4
14 INT162196 Binding of Tyrp1 2 0.31 0.69 1.35
15 INT38737 Localization of TYRP1 2 0.68 0.5 0.97
16 INT49024 Transcription of TYRP1 3 0.66 0.96 0.9
17 INT30038 Negative_regulation of Binding of TYRP1 1 0.42 0 0.72
18 INT126213 Regulation of Gene_expression of TYRP1 2 0.44 0.51 0.55
19 INT114527 Positive_regulation of Regulation of TYRP1 1 0.45 0.43 0.3
20 INT91597 Negative_regulation of Positive_regulation of TYRP1 1 0.41 0.09 0.23
21 INT136228 Phosphorylation of TYRP1 1 0.80 0.17 0.21
22 INT196100 Localization of Tyrp1 3 0.36 0 0.19
23 INT279733 Regulation of Regulation of TYRP1 1 0.01 0 0.18
24 INT323337 Positive_regulation of Negative_regulation of Tyrp1 1 0.15 0.86 0.11
25 INT268070 Negative_regulation of Positive_regulation of Tyrp1 1 0.23 0.21 0.03
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