GO:0043484

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Name regulation of RNA splicing
Categary Process
Go Slim No
Go Link GO:0043484
Unique Molecular Interactions 147
Total Molecular Interactions 244
Total Single Events 976
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of RNA splicing. They are ordered first by their pain relevance and then by number of times they were reported for regulation of RNA splicing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
3 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
4 INT125696 Binding of OPRM1 and SNRNP70 1 0.06 0.99 1.15
5 INT278224 Binding of ACSM3 and SNRNP70 1 0.04 3.76 1.01
6 INT92872 SON Positive_regulation of IL1RN 1 0.06 0.64 0.65
7 INT236492 Gtf3a Regulation of SNRNP70 1 0.00 0.52 0.56
8 INT278227 Binding of MBNL1 and SNRNP70 1 0.01 2.05 0.54
9 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
10 INT297152 Binding of PRTN3 and SNRNP70 1 0.40 1.27 0.5
11 INT251731 Binding of CD70 and SNRNP70 1 0.04 0.84 0.49
12 INT307675 Binding of IL1R1 and SNRNP70 1 0.02 1.05 0.45
13 INT352822 SNRNP70 Regulation of Tst 1 0.34 0.46 0.36
14 INT278225 Binding of FOSB and SNRNP70 1 0.00 1.22 0.36
15 INT353669 Binding of SNRNP70 and CD209 1 0.04 6.08 0.35
16 INT92871 Positive_regulation of SON Positive_regulation of IL1RN 1 0.06 0.33 0.34
17 INT329954 Binding of PRKCQ and SNRNP70 1 0.07 0.65 0.33
18 INT92870 SON Regulation of IL1A 1 0.01 0.31 0.32
19 INT92869 SON Regulation of TNF 1 0.03 0.31 0.32
20 INT350145 Binding of SNRNP70 and ERAL1 1 0.05 1.29 0.28
21 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28
22 INT277317 Binding of Celf1 and Slc6a11 1 0.19 0.06 0.26
23 INT319229 Binding of SNRNP70 and Aia1 2 0.00 2.92 0.25
24 INT177982 Binding of RUNX1 and SNRNP70 1 0.01 0.89 0.21
25 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21
26 INT313498 Binding of ALOX5 and SNRNP70 1 0.05 2.7 0.21
27 INT350151 Binding of SNRNP70 and SH2B3 1 0.13 1.22 0.2
28 INT350152 Binding of ATXN2 and SNRNP70 1 0.13 1.22 0.2
29 INT242037 Binding of CRP and SNRNP70 3 0.07 4.62 0.19
30 INT195424 SNRNP70 Negative_regulation of GBE1 1 0.00 0.22 0.19
31 INT230464 Binding of SNRNP70 and TLR1 1 0.02 1.2 0.17
32 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14
33 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12
34 INT162763 Binding of Gh and Son 1 0.39 0.09 0.12
35 INT209952 Binding of SNRNP70 and IGKV2-19 1 0.00 0.47 0.11
36 INT313505 Binding of SNRNP70 and CXADRP1 1 0.00 1.15 0.1
37 INT214138 Son Regulation of Gene_expression of Pomc 1 0.05 0.1 0.09
38 INT214154 Binding of Cck and Son 1 0.02 0.1 0.09
39 INT225805 Binding of SNRNP70 and Enpp1 1 0.42 1.43 0.09
40 INT261627 Binding of CPD and SNRNP70 1 0.01 0.36 0.08
41 INT277319 Gene_expression of Celf1 Positive_regulation of Positive_regulation of Slc6a11 1 0.24 0.08 0.08
42 INT277313 Negative_regulation of Mbnl1 Positive_regulation of Positive_regulation of Slc6a11 1 0.52 0.08 0.08
43 INT280821 Son Regulation of Gene_expression of gr 1 0.01 0.18 0.08
44 INT230462 Binding of SNRNP70 and TH1L 1 0.00 0.99 0.08
45 INT210897 Binding of SNRNP70 and IGHD1-14 1 0.01 1.63 0.08
46 INT162762 Ghrl Regulation of Son 1 0.36 0 0.07
47 INT329552 Binding of PPARA and SNRNP70 1 0.01 1.3 0.07
48 INT313506 Binding of ICAM1 and SNRNP70 1 0.02 1.08 0.06
49 INT242035 Binding of SNRNP70 and CHDH 1 0.02 3.41 0.06
50 INT248344 Binding of IL10 and SNRNP70 1 0.04 0.6 0.05
51 INT313504 Binding of ALOX5AP and SNRNP70 1 0.04 0.5 0.05
52 INT238034 Binding of DMD and SNRNP70 1 0.00 1.18 0.04
53 INT225808 SNRNP70 Regulation of Enpp1 1 0.30 0.71 0.04
54 INT313500 Binding of SELE and SNRNP70 1 0.01 0.55 0.04
55 INT313553 Binding of SNRNP70 and Cor 1 0.00 0.54 0.03
56 INT238032 Binding of SNRNP70 and OPLL 1 0.00 0.13 0.03
57 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
58 INT194484 Binding of SNRNP70 and Chol1 1 0.00 0.64 0.03
59 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0
60 INT289626 Binding of SNRNP70 and SUGT1 3 0.03 2.49 0
61 INT272516 Binding of Celf1 and Tpt1 2 0.05 0.07 0
62 INT251961 Binding of LDLR and SNRNP70 2 0.04 0.55 0
63 INT247442 Binding of HSD11B1 and SNRNP70 2 0.04 1.3 0
64 INT287374 Binding of SNRNP70 and rs 1 0.03 1.7 0
65 INT255143 Regulation of Binding of Mbnl1 and Hnrnph1 1 0.07 0.07 0
66 INT194485 SNRNP70 Regulation of Ppara 1 0.00 0.53 0
67 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
68 INT255146 Negative_regulation of Binding of Dmpk and Hnrnph1 1 0.11 0 0
69 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
70 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0
71 INT353663 Binding of SNRNP70 and SENP8 1 0.01 1.4 0
72 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0
73 INT311387 Binding of Celf1 and Mbnl1 1 0.20 0.25 0
74 INT311405 CCND3 Regulation of Celf1 1 0.41 0.14 0
75 INT279905 Binding of SNRNP70 and TGS1 1 0.01 1.85 0
76 INT247441 Binding of APOC3 and SNRNP70 1 0.04 0.26 0
77 INT332905 Binding of LPL and SNRNP70 1 0.01 1.34 0
78 INT329990 Binding of KCNMA1 and SNRNP70 1 0.03 0.96 0
79 INT339048 SNRNP70 Regulation of PSORS2 1 0.00 0.45 0
80 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0
81 INT272518 Positive_regulation of Binding of Ccnd1 and Celf1 1 0.01 0 0
82 INT277315 Binding of Insr and Mbnl1 1 0.18 1.1 0
83 INT268331 Binding of SNRNP70 and CHD7 1 0.01 1.91 0
84 INT287372 Binding of SNRNP70 and Loxl1 1 0.02 0.38 0
85 INT287373 Positive_regulation of Binding of SNRNP70 and Loxl1 1 0.02 0.19 0
86 INT239185 Binding of Clk1 and Shc1 1 0.04 2.42 0
87 INT311389 Positive_regulation of Binding of Celf1 and Eif2s2 1 0.17 0.59 0
88 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0
89 INT272522 Celf1 Positive_regulation of Phosphorylation of CEBPD 1 0.03 0.52 0
90 INT311381 Phosphorylation of Akt1 Regulation of Celf1 1 0.10 0.14 0
91 INT266453 SNRNP70 Regulation of Acot1 1 0.00 0.53 0
92 INT255144 Binding of Dmpk and Hnrnph1 1 0.09 0 0
93 INT339042 SNRNP70 Regulation of RS1 1 0.00 0.94 0
94 INT311379 Celf1 Negative_regulation of Mbnl1 1 0.24 0.26 0
95 INT302593 Binding of SNRNP70 and Egfl7 1 0.00 0 0
96 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
97 INT311385 Gopc Regulation of Celf1 1 0.04 0.14 0
98 INT311380 Positive_regulation of Celf1 Negative_regulation of Mbnl1 1 0.26 0.26 0
99 INT279898 SNRNP70 Regulation of EMR1 1 0.00 0.93 0
100 INT255147 Binding of Dmpk and Mbnl1 1 0.34 0 0
101 INT205588 Binding of SNRNP70 and PPT2 1 0.03 0.26 0
102 INT277311 Mbnl1 Regulation of Gene_expression of Slc6a11 1 0.50 0.06 0
103 INT189560 Binding of MBNL1 and CCNL1 1 0.12 0.22 0
104 INT301096 SNRNP70 Regulation of Gene_expression of HSPA8 1 0.04 0.32 0
105 INT232515 Binding of SNRNP70 and ACCS 1 0.01 0.75 0
106 INT311397 Binding of Celf1 and Gopc 1 0.04 0.09 0
107 INT310202 Binding of RS1 and SNRNP70 1 0.05 1.77 0
108 INT208051 Binding of SNRNP70 and Accn1 1 0.01 1.81 0
109 INT217877 Binding of CLK1 and BCC1 1 0.00 0 0
110 INT311375 Phosphorylation of Prkca Positive_regulation of Celf1 1 0.04 0.1 0
111 INT255145 Binding of Mbnl1 and Hnrnph1 1 0.09 0.15 0
112 INT232575 SNRNP70 Regulation of SOD1 1 0.12 0.65 0
113 INT332943 Binding of SNRNP70 and Adipoq 1 0.00 1.35 0
114 INT277312 Regulation of Binding of Upf1 and Mbnl1 1 0.01 0.36 0
115 INT279893 Binding of SNRNP70 and USF1 1 0.04 0.78 0
116 INT339045 Binding of RENBP and SNRNP70 1 0.01 0.38 0
117 INT272515 Akt1 Positive_regulation of Binding of Celf1 1 0.03 0 0
118 INT353664 SNRNP70 Regulation of Gene_expression of CD209 1 0.05 1.62 0
119 INT301097 Binding of MECP2 and SNRNP70 1 0.01 1.15 0
120 INT329992 Binding of SNRNP70 and AKAP6 1 0.03 0.95 0
121 INT311394 Binding of Celf1 and Eif2s2 1 0.12 1.67 0
122 INT232518 Binding of SGCB and SNRNP70 1 0.00 0.77 0
123 INT209951 Binding of KCNJ13 and SNRNP70 1 0.00 0 0
124 INT311391 Binding of Celf1 and Dmpk 1 0.34 0.09 0
125 INT311383 Mbnl1 Regulation of Insr 1 0.00 0.24 0
126 INT277309 Binding of Upf1 and Mbnl1 1 0.01 0.71 0
127 INT223319 Binding of ESR2 and SNRNP70 1 0.40 0 0
128 INT277308 Upf1 Regulation of Regulation of Celf1 1 0.00 1.05 0
129 INT302597 SNRNP70 Negative_regulation of Egfl7 1 0.00 0 0
130 INT287371 SNRNP70 Regulation of Gene_expression of Loxl1 1 0.01 0.9 0
131 INT311376 Binding of Ccnd3 and Celf1 1 0.06 0.07 0
132 INT279910 SNRNP70 Regulation of TGS1 1 0.01 0.76 0
133 INT311386 Celf1 Regulation of Insr 1 0.00 0.24 0
134 INT311388 Mbnl1 Positive_regulation of Binding of Celf1 1 0.26 0.13 0
135 INT311396 Akt1 Regulation of Celf1 1 0.04 0.14 0
136 INT277314 Celf1 Regulation of Gene_expression of Slc6a11 1 0.23 0.06 0
137 INT332904 Binding of LEP and SNRNP70 1 0.00 1.34 0
138 INT311403 CDKN2A Regulation of Celf1 1 0.41 0.14 0
139 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of RNA splicing. They are ordered first by their pain relevance and then by number of times they were reported in regulation of RNA splicing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3
2 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5
3 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28
4 INT100384 Regulation of SNRNP70 24 0.60 11 3.56
5 INT156180 Positive_regulation of Gene_expression of SNRNP70 14 0.49 4.54 2.13
6 INT69133 Negative_regulation of SON 3 0.10 1.79 1.96
7 INT178841 Localization of SNRNP70 27 0.78 10.35 1.71
8 INT223323 Transcription of SNRNP70 4 0.67 3.03 1.7
9 INT33413 Positive_regulation of SON 9 0.39 0.09 1.49
10 INT165702 Gene_expression of Son 11 0.35 2.18 1.48
11 INT260874 Positive_regulation of Binding of SNRNP70 3 0.49 2.17 0.91
12 INT58550 Gene_expression of SON 8 0.43 0.99 0.88
13 INT255101 Positive_regulation of Celf1 23 0.56 11.91 0.84
14 INT53848 Localization of SON 5 0.20 0.28 0.79
15 INT242255 Negative_regulation of Regulation of SNRNP70 2 0.09 0.53 0.79
16 INT81047 Negative_regulation of SNRNP70 10 0.36 4.37 0.75
17 INT33541 Positive_regulation of Son 2 0.40 0.29 0.74
18 INT255120 Gene_expression of Celf1 29 0.62 10.82 0.59
19 INT272475 Regulation of Mbnl1 15 0.61 5.39 0.56
20 INT272471 Binding of Celf1 5 0.39 4.97 0.56
21 INT255131 Gene_expression of Mbnl1 34 0.77 10.44 0.55
22 INT249339 Gene_expression of MBNL1 4 0.17 3.64 0.53
23 INT277278 Regulation of Celf1 4 0.49 4.63 0.48
24 INT255113 Positive_regulation of Gene_expression of Mbnl1 15 0.69 3.28 0.47
25 INT255112 Negative_regulation of Mbnl1 22 0.58 8.5 0.45
26 INT290037 Negative_regulation of Gene_expression of SNRNP70 4 0.07 3.64 0.45
27 INT255135 Positive_regulation of Gene_expression of Celf1 18 0.56 5.84 0.43
28 INT165701 Localization of Son 3 0.39 0.06 0.4
29 INT235841 Negative_regulation of Gene_expression of Clk1 1 0.11 0.62 0.4
30 INT80108 Regulation of SON 1 0.02 0.59 0.38
31 INT50884 Binding of MBNL1 3 0.23 0.32 0.37
32 INT235850 Gene_expression of Clk1 1 0.15 0.56 0.37
33 INT68333 Negative_regulation of Localization of SON 1 0.10 0 0.35
34 INT255132 Positive_regulation of Mbnl1 15 0.54 2.58 0.27
35 INT255123 Localization of Mbnl1 7 0.80 3.76 0.24
36 INT277269 Positive_regulation of Binding of Celf1 2 0.40 0.89 0.24
37 INT336834 Regulation of Transcription of SNRNP70 1 0.02 1.06 0.24
38 INT280789 Transcription of Son 1 0.09 0 0.23
39 INT59894 Negative_regulation of Positive_regulation of SON 1 0.36 0 0.19
40 INT250094 Positive_regulation of Gene_expression of SON 1 0.13 0 0.15
41 INT265699 Negative_regulation of Gene_expression of Son 1 0.15 1.49 0.14
42 INT280796 Negative_regulation of Son 1 0.06 0.42 0.14
43 INT277270 Regulation of Regulation of Mbnl1 1 0.45 0.42 0.14
44 INT222897 Regulation of Gene_expression of SNRNP70 5 0.44 1.44 0.13
45 INT255125 Localization of Celf1 7 0.60 2.84 0.11
46 INT255128 Binding of Mbnl1 13 0.37 4.34 0.09
47 INT255099 Regulation of Binding of Mbnl1 1 0.42 0.3 0.09
48 INT265860 Positive_regulation of Regulation of SNRNP70 1 0.08 0.66 0.09
49 INT272486 Phosphorylation of Celf1 10 0.66 4.63 0.08
50 INT239166 Negative_regulation of Clk1 1 0.06 0.74 0.06
51 INT255119 Positive_regulation of Positive_regulation of Celf1 3 0.40 1.26 0.05
52 INT272467 Positive_regulation of Phosphorylation of Celf1 3 0.56 1.61 0.05
53 INT255111 Positive_regulation of Positive_regulation of Mbnl1 1 0.47 0.54 0.05
54 INT311331 Negative_regulation of Binding of Celf1 1 0.34 0 0.04
55 INT217902 Regulation of CLK1 1 0.12 0 0.04
56 INT217903 Gene_expression of CLK1 1 0.16 0 0.04
57 INT255109 Binding of Hnrnph1 3 0.10 0.22 0.03
58 INT255096 Regulation of Gene_expression of Mbnl1 2 0.45 0.72 0
59 INT287367 Regulation of Binding of SNRNP70 2 0.44 1.01 0
60 INT272478 Regulation of Phosphorylation of Celf1 2 0.49 0.36 0
61 INT255108 Regulation of Gene_expression of Celf1 2 0.36 0.18 0
62 INT272459 Negative_regulation of Phosphorylation of Celf1 2 0.47 0.55 0
63 INT255103 Negative_regulation of Hnrnph1 1 0.11 0 0
64 INT311306 Regulation of Transcription of Celf1 1 0.22 0.29 0
65 INT255130 Positive_regulation of Binding of Mbnl1 1 0.47 0.75 0
66 INT248068 Negative_regulation of Binding of SNRNP70 1 0.41 0.09 0
67 INT311310 Regulation of Binding of Celf1 1 0.36 0.88 0
68 INT311340 Positive_regulation of Transcription of Celf1 1 0.40 0.08 0
69 INT311276 Negative_regulation of Gene_expression of Mbnl1 1 0.37 0.32 0
70 INT255124 Positive_regulation of Negative_regulation of Hnrnph1 1 0.11 0 0
71 INT255114 Negative_regulation of Celf1 1 0.07 0.29 0
72 INT277262 Protein_catabolism of Mbnl1 1 0.88 0.11 0
73 INT311342 Positive_regulation of Negative_regulation of Mbnl1 1 0.30 0.26 0
74 INT311291 Regulation of MBNL1 1 0.02 0.69 0
75 INT255105 Negative_regulation of Gene_expression of Celf1 1 0.05 0.21 0
76 INT277281 Positive_regulation of Regulation of Mbnl1 1 0.50 0.16 0
77 INT205598 Positive_regulation of Positive_regulation of SNRNP70 1 0.49 0.24 0
78 INT311302 Positive_regulation of Protein_catabolism of Celf1 1 0.40 0.13 0
79 INT311322 Transcription of Celf1 1 0.55 0.38 0
80 INT255104 Positive_regulation of Localization of Mbnl1 1 0.47 0 0
81 INT255094 Negative_regulation of Positive_regulation of Mbnl1 1 0.40 0 0
82 INT311327 Protein_catabolism of Celf1 1 0.71 0.13 0
83 INT249344 Positive_regulation of MBNL1 1 0.01 2.88 0
84 INT341298 Regulation of Gene_expression of MBNL1 1 0.11 0 0
85 INT255098 Regulation of Negative_regulation of Mbnl1 1 0.25 0 0
86 INT189632 Negative_regulation of MBNL1 1 0.18 0.29 0
87 INT311330 Negative_regulation of Positive_regulation of Celf1 1 0.35 0.85 0
88 INT311315 Regulation of Positive_regulation of Celf1 1 0.22 0.29 0
89 INT272487 Transcription of Mbnl1 1 0.54 0.48 0
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