GO:0043490

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Name malate-aspartate shuttle
Categary Process
Go Slim No
Go Link GO:0043490
Unique Molecular Interactions 20
Total Molecular Interactions 27
Total Single Events 346
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for malate-aspartate shuttle. They are ordered first by their pain relevance and then by number of times they were reported for malate-aspartate shuttle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
2 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
3 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
4 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
5 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
6 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
7 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
8 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
9 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
10 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27
11 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27
12 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27
13 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
14 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
15 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
16 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
17 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08
18 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
19 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
20 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for malate-aspartate shuttle. They are ordered first by their pain relevance and then by number of times they were reported in malate-aspartate shuttle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
2 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
3 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
4 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
5 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
6 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
7 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
8 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
9 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
10 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
11 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
12 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
13 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
14 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
15 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
16 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
17 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
18 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
19 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
20 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
21 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
22 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
23 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
24 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
25 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
26 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
27 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
28 INT187801 Negative_regulation of Binding of Slc1a3 1 0.26 0.25 1.26
29 INT165458 Regulation of Gene_expression of SLC1A3 1 0.23 0.26 1.08
30 INT187804 Positive_regulation of Localization of Slc1a3 1 0.26 0.84 1.06
31 INT179751 Negative_regulation of Gene_expression of SLC1A3 1 0.19 0.75 1.05
32 INT127051 Positive_regulation of Transcription of Slc1a3 2 0.14 0.37 0.89
33 INT191831 Positive_regulation of Slc1a3 6 0.49 3.66 0.87
34 INT352660 Transcription of SLC1A3 1 0.05 0.76 0.8
35 INT179748 Regulation of SLC1A3 1 0.15 0.09 0.66
36 INT352659 Positive_regulation of Transcription of SLC1A3 1 0.04 0.39 0.43
37 INT198078 Positive_regulation of Negative_regulation of Slc1a3 1 0.40 0.15 0.38
38 INT150431 Regulation of Transcription of Slc1a3 1 0.10 0.33 0.37
39 INT198071 Regulation of Slc1a3 1 0.36 0.08 0.35
40 INT206487 Binding of SLC1A3 2 0.36 0.21 0.17
41 INT198065 Binding of Slc1a3 3 0.30 0 0.05
42 INT277525 Transcription of Slc1a3 1 0.59 0.09 0.05
43 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04
44 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04
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