GO:0043491

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Name protein kinase B signaling cascade
Categary Process
Go Slim No
Go Link GO:0043491
Unique Molecular Interactions 2430
Total Molecular Interactions 3442
Total Single Events 28077
Pain Genes Associated 54

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein kinase B signaling cascade. They are ordered first by their pain relevance and then by number of times they were reported for protein kinase B signaling cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
4 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
5 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
6 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
7 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
8 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
9 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
10 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
11 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
12 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
13 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
14 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
15 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
16 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
17 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
18 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
19 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
20 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
21 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
22 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
23 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
24 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
25 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
26 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
27 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
28 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
29 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
30 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
31 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
32 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
33 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
34 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
35 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
36 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
37 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
38 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
39 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
40 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
41 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
42 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
43 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
44 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
45 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
46 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
47 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
48 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
49 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
50 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
51 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
52 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
53 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
54 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
55 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
56 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
57 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
58 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
59 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
60 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
61 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
62 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
63 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
64 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
65 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
66 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
67 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
68 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
69 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
70 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
71 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
72 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
73 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
74 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
75 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
76 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
77 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
78 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
79 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
80 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
81 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
82 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
83 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
84 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
85 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
86 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
87 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
88 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
89 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
90 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
91 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
92 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
93 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
94 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
95 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
96 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
97 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
98 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
99 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
100 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
101 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
102 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
103 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
104 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
105 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
106 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
107 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
108 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
109 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
110 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
111 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
112 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
113 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
114 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
115 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
116 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
117 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
118 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
119 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
120 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
121 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
122 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
123 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
124 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
125 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
126 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
127 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
128 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
129 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
130 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
131 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
132 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
133 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
134 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
135 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
136 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
137 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
138 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
139 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
140 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
141 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
142 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
143 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
144 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
145 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
146 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
147 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
148 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
149 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
150 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
151 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
152 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
153 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
154 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
155 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
156 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
157 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
158 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
159 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
160 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
161 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
162 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
163 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
164 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
165 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
166 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
167 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
168 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
169 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
170 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
171 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
172 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
173 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
174 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
175 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
176 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
177 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
178 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
179 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
180 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
181 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
182 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
183 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
184 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
185 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
186 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
187 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
188 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
189 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
190 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
191 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
192 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
193 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
194 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
195 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
196 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
197 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
198 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
199 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
200 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein kinase B signaling cascade. They are ordered first by their pain relevance and then by number of times they were reported in protein kinase B signaling cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
10 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
11 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
12 INT9660 Regulation of TNF 363 0.62 312.94 139.99
13 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
14 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
15 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
16 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
17 INT10166 Localization of Tnf 237 0.81 153.95 88.64
18 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
19 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
20 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
21 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
22 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
23 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
24 INT6849 Localization of IL1B 229 0.81 112.56 69.63
25 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
26 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
27 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
28 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
29 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
30 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
31 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
32 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
33 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
34 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
35 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
36 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
37 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
38 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
39 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
40 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
41 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
42 INT13354 Transcription of TNF 108 0.72 85.81 42.32
43 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
44 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
45 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
46 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
47 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
48 INT6484 Binding of IL1B 122 0.47 75.84 35.07
49 INT65698 Localization of CCL2 118 0.81 77.54 32.69
50 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
51 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
52 INT35406 Localization of Tnf 94 0.81 64.63 31.65
53 INT9347 Localization of Il1b 58 0.81 26.13 31.53
54 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
55 INT82882 Localization of Ccl2 61 0.80 41.96 28
56 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
57 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
58 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
59 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
60 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
61 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
62 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
63 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
64 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
65 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
66 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
67 INT48081 Localization of Il1b 46 0.80 21.59 22.4
68 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
69 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
70 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
71 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
72 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
73 INT78901 Localization of CCL5 67 0.78 40.79 20.59
74 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
75 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
76 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
77 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
78 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
79 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
80 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
81 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
82 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
83 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
84 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
85 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
86 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
87 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
88 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
89 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
90 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
91 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
92 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
93 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
94 INT10173 Binding of Tnf 45 0.48 35.6 14.32
95 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
96 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
97 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
98 INT148301 Gene_expression of P2ry12 23 0.75 14.24 13.63
99 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
100 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
101 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
102 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
103 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
104 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
105 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
106 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
107 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
108 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
109 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
110 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
111 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
112 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
113 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
114 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
115 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
116 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
117 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
118 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
119 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
120 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
121 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
122 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
123 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
124 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
125 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
126 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
127 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
128 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
129 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
130 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
131 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
132 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
133 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
134 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
135 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
136 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
137 INT68299 Binding of Tnf 17 0.39 12.55 7.49
138 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
139 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
140 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
141 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
142 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
143 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
144 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
145 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
146 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
147 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
148 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
149 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
150 INT120895 Binding of CCL2 22 0.37 15.86 6.55
151 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
152 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
153 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
154 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
155 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
156 INT148308 Regulation of P2ry12 8 0.44 6.2 6.23
157 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
158 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
159 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
160 INT80750 Binding of Il1b 11 0.47 7.97 5.95
161 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
162 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
163 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
164 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
165 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
166 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
167 INT10705 Binding of Il1b 9 0.36 2.8 5.53
168 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
169 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
170 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
171 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
172 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
173 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
174 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
175 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
176 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
177 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
178 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
179 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
180 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
181 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
182 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
183 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
184 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
185 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
186 INT134657 Localization of Akt1 37 0.68 11.58 4.62
187 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
188 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
189 INT2213 Regulation of EP300 10 0.54 4.72 4.5
190 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
191 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
192 INT150464 Positive_regulation of P2ry12 5 0.67 4.39 4.3
193 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
194 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
195 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
196 INT75136 Binding of Akt1 27 0.27 8.81 4.15
197 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
198 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
199 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
200 INT165182 Gene_expression of P2ry12 4 0.65 4.29 4.08
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