GO:0043496

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Name regulation of protein homodimerization activity
Categary Process
Go Slim No
Go Link GO:0043496
Unique Molecular Interactions 403
Total Molecular Interactions 521
Total Single Events 5132
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of protein homodimerization activity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of protein homodimerization activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
3 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
4 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
5 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
6 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
7 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
8 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
9 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
10 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
11 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
12 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
13 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
14 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
15 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
16 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
17 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
18 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
19 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
20 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
21 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
22 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
23 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
24 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
25 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
26 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
27 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
28 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
29 INT165633 Binding of Ica1 and Cfp 1 0.05 0 0.4
30 INT353836 Binding of CEACAM7 and ICA1 1 0.08 0.32 0.39
31 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
32 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
33 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
34 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
35 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
36 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
37 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
38 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
39 INT146248 Pcbd1 Positive_regulation of Trpv1 1 0.02 0 0.31
40 INT146247 Pcbd1 Positive_regulation of Trpa1 1 0.02 0 0.31
41 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
42 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
43 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
44 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
45 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
46 INT56904 Binding of GCY and ICA1 1 0.15 1.5 0.28
47 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
48 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
49 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
50 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
51 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
52 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
53 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
54 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
55 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
56 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21
57 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19
58 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19
59 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
60 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
61 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
62 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
63 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
64 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
65 INT343852 Binding of TRAF1 and TICAM1 1 0.03 0.19 0.17
66 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
67 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
68 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
69 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
70 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17
71 INT343915 Binding of Traf1 and TICAM1 1 0.08 0.19 0.17
72 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
73 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
74 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
75 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15
76 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
77 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
78 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
79 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
80 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
81 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
82 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
83 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
84 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
85 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
86 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
87 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
88 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
89 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
90 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
91 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
92 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
93 INT324831 Binding of TRIM63 and Ticam1 1 0.01 0.09 0.12
94 INT254229 Binding of Ticam1 and Positive_regulation of Binding of IFNA1 1 0.02 0.3 0.12
95 INT254207 Ticam1 Positive_regulation of Ik 1 0.00 0.14 0.12
96 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
97 INT254227 Binding of Ripk1 and Ticam1 3 0.07 0.18 0.11
98 INT254215 Binding of Tlr4 and Ticam1 2 0.09 0.76 0.11
99 INT334264 Binding of Gtf3a and Ticam1 1 0.00 0.18 0.11
100 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
101 INT254220 Binding of Ticam1 and Sarm1 1 0.09 0.22 0.11
102 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
103 INT324869 Binding of Jun and Ticam1 1 0.01 0.76 0.11
104 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
105 INT324870 Binding of Ticam1 and Tlr3 1 0.03 0.76 0.11
106 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1
107 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
108 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
109 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
110 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
111 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
112 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
113 INT343845 TICAM1 Positive_regulation of TIRAP 1 0.05 0.25 0.09
114 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
115 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
116 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
117 INT54096 NRG1 Regulation of Protein_catabolism of Fgg 1 0.01 0 0.09
118 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
119 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
120 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
121 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
122 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
123 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
124 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
125 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
126 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
127 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
128 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
129 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
130 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
131 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
132 INT346499 Mal Positive_regulation of TICAM1 1 0.06 0.66 0.07
133 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
134 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
135 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
136 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
137 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
138 INT346449 TICAM1 Positive_regulation of TBK1 1 0.01 0.45 0.06
139 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
140 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
141 INT346454 TICAM1 Positive_regulation of IKBKE 1 0.01 0.45 0.06
142 INT350478 Tirap Regulation of Ticam1 1 0.07 0.06 0.05
143 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
144 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
145 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
146 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
147 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
148 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
149 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
150 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
151 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
152 INT348819 Ica1 Positive_regulation of Gene_expression of IFNA1 1 0.01 0.21 0.04
153 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
154 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
155 INT350800 Binding of TLR3 and TICAM1 1 0.01 0 0.04
156 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
157 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
158 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
159 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
160 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
161 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
162 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
163 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
164 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
165 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
166 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
167 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
168 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
169 INT229204 Olr1254 Negative_regulation of Gene_expression of Bcl2 1 0.02 0.18 0.03
170 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
171 INT348028 Binding of Traf3 and Ticam1 1 0.01 0.56 0.03
172 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
173 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03
174 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
175 INT170910 Negative_regulation of Pcbd1 Positive_regulation of Positive_regulation of Mapk8 1 0.00 0.21 0.03
176 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
177 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
178 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
179 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
180 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
181 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
182 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
183 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
184 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
185 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
186 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0
187 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
188 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
189 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
190 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
191 INT185851 BID Positive_regulation of BAK1 1 0.43 0.73 0
192 INT295047 Binding of Bcl2 and Nr4a1 1 0.04 0.96 0
193 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0
194 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
195 INT161438 Penk Positive_regulation of Localization of ICA1 1 0.00 0 0
196 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
197 INT295046 Bcl2 Regulation of Gene_expression of Nr4a1 1 0.02 0.92 0
198 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
199 INT253474 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Bcl2 1 0.04 1.27 0
200 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of protein homodimerization activity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of protein homodimerization activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
5 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
6 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
7 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
8 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
9 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
10 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
11 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
12 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
13 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
14 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
15 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
16 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
17 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
18 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
19 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
20 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
21 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
22 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
23 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
24 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
25 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
26 INT52020 Negative_regulation of ICA1 7 0.31 1.56 5.71
27 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
28 INT145929 Regulation of Bax 20 0.60 18.12 5.35
29 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
30 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
31 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
32 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
33 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
34 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
35 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16
36 INT84686 Regulation of BAX 26 0.49 28.54 4.13
37 INT123752 Regulation of Bax 19 0.60 16.45 4
38 INT112692 Localization of Bax 31 0.80 20.97 3.98
39 INT61495 Positive_regulation of ICA1 8 0.49 4.19 3.87
40 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
41 INT124579 Localization of BAX 35 0.78 30.31 3.43
42 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
43 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
44 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
45 INT105884 Binding of Bcl2 19 0.35 15.67 3
46 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
47 INT134811 Gene_expression of ICA1 22 0.44 6.47 2.42
48 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
49 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
50 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
51 INT103966 Negative_regulation of Gene_expression of BAX 9 0.56 7.95 2.14
52 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12
53 INT154970 Localization of Bax 15 0.74 11.12 2.11
54 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
55 INT98836 Transcription of Bax 6 0.69 5.04 1.96
56 INT134919 Binding of Ticam1 6 0.18 1.12 1.94
57 INT134442 Transcription of Bax 14 0.67 7.6 1.9
58 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
59 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
60 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
61 INT134443 Binding of Bax 10 0.47 5.62 1.84
62 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
63 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
64 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
65 INT25240 Negative_regulation of Pcbd1 11 0.43 3.1 1.59
66 INT152198 Binding of ICA1 3 0.31 1.7 1.55
67 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
68 INT152193 Positive_regulation of Binding of ICA1 1 0.41 1.66 1.53
69 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
70 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
71 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
72 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
73 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
74 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
75 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
76 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
77 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
78 INT30851 Gene_expression of NRG1 8 0.67 4.64 1.12
79 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
80 INT70021 Localization of BCL2 23 0.74 21.6 1.09
81 INT152195 Regulation of ICA1 1 0.37 1.07 1.08
82 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
83 INT134917 Localization of Ticam1 2 0.51 0.6 0.99
84 INT19084 Negative_regulation of NRG1 5 0.42 4.9 0.96
85 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
86 INT98134 Binding of BAX 17 0.39 11.45 0.93
87 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
88 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
89 INT134912 Positive_regulation of Localization of Ticam1 1 0.24 0.32 0.87
90 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
91 INT9033 Positive_regulation of Pcbd1 14 0.39 3.88 0.86
92 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85
93 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
94 INT82896 Transcription of BAX 3 0.67 4.61 0.8
95 INT70019 Binding of BCL2 25 0.47 17.55 0.79
96 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
97 INT148984 Positive_regulation of Localization of BAX 6 0.48 5.29 0.77
98 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
99 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
100 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
101 INT14040 Binding of Bak1 2 0.30 0.55 0.72
102 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
103 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
104 INT290081 Regulation of NRG1 7 0.26 5.24 0.59
105 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
106 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
107 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
108 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
109 INT176242 Binding of Bax 10 0.42 10.18 0.52
110 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
111 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
112 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
113 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
114 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
115 INT19083 Positive_regulation of NRG1 3 0.20 0.65 0.48
116 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
117 INT229243 Negative_regulation of Phosphorylation of BAX 1 0.18 2.32 0.47
118 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
119 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
120 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
121 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
122 INT105888 Phosphorylation of BAX 9 0.80 4.78 0.4
123 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
124 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
125 INT165631 Binding of Ica1 1 0.35 0 0.4
126 INT39150 Gene_expression of Pcbd1 5 0.28 1.3 0.38
127 INT229233 Positive_regulation of Phosphorylation of BAX 1 0.21 1.94 0.38
128 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
129 INT250167 Negative_regulation of Ticam1 3 0.29 2.03 0.37
130 INT290096 Regulation of Gene_expression of NRG1 2 0.06 2.21 0.35
131 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
132 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
133 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
134 INT172216 Binding of Bak1 5 0.25 8.48 0.33
135 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
136 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
137 INT196471 Negative_regulation of Gene_expression of ICA1 2 0.10 1.51 0.32
138 INT122950 Binding of BAK1 16 0.41 12.85 0.31
139 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
140 INT109530 Negative_regulation of Positive_regulation of BAX 3 0.42 3.01 0.3
141 INT125797 Localization of ICA1 2 0.36 0.6 0.29
142 INT82900 Positive_regulation of Transcription of BAX 2 0.49 1.86 0.29
143 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
144 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
145 INT9034 Regulation of Pcbd1 6 0.20 3.28 0.28
146 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
147 INT170924 Negative_regulation of Positive_regulation of Pcbd1 1 0.02 0.4 0.26
148 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
149 INT254195 Gene_expression of Ticam1 3 0.29 0.46 0.24
150 INT172227 Regulation of Localization of BAX 3 0.26 4.79 0.24
151 INT203557 Transcription of NRG1 2 0.31 0.7 0.24
152 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
153 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
154 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
155 INT165632 Gene_expression of Ica1 1 0.63 0 0.22
156 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
157 INT187555 Transcription of BAK1 3 0.19 2.6 0.21
158 INT187556 Regulation of Transcription of BAK1 1 0.02 1.22 0.21
159 INT187553 Regulation of Transcription of BAX 1 0.37 1.21 0.21
160 INT282088 Localization of Bak1 6 0.54 3.78 0.19
161 INT175569 Binding of Pcbd1 1 0.17 0.96 0.19
162 INT324768 Positive_regulation of Ticam1 2 0.16 0.14 0.18
163 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
164 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
165 INT198036 Negative_regulation of BAK1 5 0.27 5.98 0.17
166 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
167 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
168 INT54093 Protein_catabolism of NRG1 1 0.26 0 0.16
169 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
170 INT324781 Protein_catabolism of Ticam1 1 0.27 0.74 0.15
171 INT102109 Protein_catabolism of Bcl2 1 0.65 0.55 0.15
172 INT254190 Positive_regulation of Binding of Ticam1 1 0.22 0.32 0.15
173 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
174 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13
175 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
176 INT185872 Localization of BAK1 6 0.74 11.28 0.12
177 INT265485 Positive_regulation of Localization of BAK1 4 0.50 5.17 0.12
178 INT185907 Positive_regulation of Binding of BAK1 2 0.60 1.59 0.12
179 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
180 INT238490 Regulation of Regulation of BAK1 1 0.19 2.56 0.12
181 INT133486 Negative_regulation of Binding of BAX 1 0.15 0.62 0.12
182 INT203559 Positive_regulation of Transcription of NRG1 1 0.22 0 0.11
183 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
184 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
185 INT54092 Regulation of Protein_catabolism of NRG1 1 0.13 0 0.09
186 INT43108 Binding of Pcbd1 2 0.12 0.16 0.08
187 INT39149 Positive_regulation of Negative_regulation of Pcbd1 1 0.14 0.08 0.08
188 INT327140 Regulation of Localization of BAK1 1 0.45 0.71 0.07
189 INT303976 Negative_regulation of Protein_catabolism of BAX 1 0.09 0.24 0.07
190 INT285012 Positive_regulation of Positive_regulation of Bak1 1 0.16 0.77 0.07
191 INT54094 Positive_regulation of Protein_catabolism of NRG1 1 0.14 0 0.07
192 INT322649 Positive_regulation of Localization of Bak1 1 0.47 1.04 0.07
193 INT303978 Protein_catabolism of BAX 1 0.13 0.24 0.07
194 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
195 INT285008 Negative_regulation of Regulation of Bak1 1 0.14 0.87 0.07
196 INT254184 Positive_regulation of Gene_expression of Ticam1 1 0.22 0.11 0.06
197 INT290102 Localization of NRG1 1 0.15 0.76 0.06
198 INT333214 Regulation of Bak1 1 0.18 1.1 0.06
199 INT268304 Negative_regulation of Gene_expression of Bak1 3 0.28 1.95 0.05
200 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
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