GO:0043508

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Name negative regulation of JUN kinase activity
Categary Process
Go Slim No
Go Link GO:0043508
Unique Molecular Interactions 18
Total Molecular Interactions 36
Total Single Events 257
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of JUN kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of JUN kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108732 Gene_expression of Gstp1 Positive_regulation of Gene_expression of Mgst1 1 0.44 0.58 0.41
2 INT223829 Binding of GSTM1 and GSTP1 2 0.41 2.78 0.39
3 INT223828 Binding of GSTP1 and MAPK8 1 0.06 1.8 0.21
4 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12
5 INT223827 MAPK8 Positive_regulation of Gene_expression of GSTP1 1 0.12 0.88 0.1
6 INT278164 GSTM1 Positive_regulation of Transcription of GSTP1 1 0.57 0.94 0.07
7 INT223825 GSTP1 Negative_regulation of MAPK8 1 0.11 1.53 0.06
8 INT143647 Negative_regulation of Mapk8ip1 Negative_regulation of Gene_expression of Fas 1 0.02 0.15 0.05
9 INT338900 MYC Positive_regulation of Gene_expression of TP73 1 0.05 0.27 0.03
10 INT268510 PDCD4 Regulation of MIR21 1 0.01 1.17 0
11 INT235649 TP73 Regulation of EFNA1 1 0.09 0.97 0
12 INT293982 MYC Negative_regulation of SFRP1 1 0.21 0.62 0
13 INT235651 TP73 Regulation of EPHA2 1 0.15 0.98 0
14 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0
15 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0
16 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of JUN kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of JUN kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133085 Gene_expression of Mapk8ip1 7 0.66 6.13 2.98
2 INT95737 Positive_regulation of Phosphorylation of Mapk8ip1 2 0.06 3.27 2.74
3 INT133083 Positive_regulation of Gene_expression of Mapk8ip1 1 0.07 3.27 2.47
4 INT95736 Phosphorylation of Mapk8ip1 2 0.10 2.84 2.32
5 INT135077 Binding of GSTP1 11 0.48 7.03 1.8
6 INT143646 Negative_regulation of Mapk8ip1 5 0.03 5.46 1.28
7 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
8 INT129006 Negative_regulation of Gstp1 1 0.34 1.85 0.65
9 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
10 INT106022 Negative_regulation of GSTP1 5 0.59 2.12 0.55
11 INT120762 Regulation of GSTP1 2 0.45 3.66 0.54
12 INT154151 Positive_regulation of TP73 5 0.67 5.71 0.52
13 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48
14 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
15 INT167981 Negative_regulation of Negative_regulation of Mapk8ip1 1 0.01 0.91 0.45
16 INT179413 Positive_regulation of Mapk8ip1 1 0.01 0.97 0.4
17 INT325423 Localization of Gstp1 1 0.06 0.85 0.37
18 INT325425 Positive_regulation of Localization of Gstp1 1 0.04 0.9 0.37
19 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35
20 INT144474 Protein_catabolism of Gstp1 1 0.06 0.57 0.33
21 INT199762 Positive_regulation of Gstp1 2 0.55 2.02 0.32
22 INT95740 Negative_regulation of Phosphorylation of Mapk8ip1 1 0.01 0 0.27
23 INT278169 Regulation of Regulation of GSTP1 1 0.45 1.1 0.25
24 INT154150 Regulation of TP73 3 0.15 2.81 0.24
25 INT97465 Regulation of PDCD4 3 0.37 3.68 0.24
26 INT154147 Gene_expression of TP73 7 0.34 3.97 0.19
27 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19
28 INT154148 Negative_regulation of Gene_expression of TP73 3 0.21 1.89 0.14
29 INT278171 Positive_regulation of Transcription of GSTP1 1 0.50 1.86 0.13
30 INT146072 Binding of TP73 2 0.12 0.58 0.1
31 INT223834 Localization of GSTP1 2 0.70 1.28 0.1
32 INT120767 Negative_regulation of Gene_expression of GSTP1 3 0.42 1.15 0.09
33 INT120771 Negative_regulation of Positive_regulation of GSTP1 1 0.30 0.39 0.08
34 INT120766 Regulation of Positive_regulation of GSTP1 1 0.32 0.39 0.08
35 INT278173 Transcription of GSTP1 1 0.68 0.93 0.07
36 INT254642 Binding of Mapk8ip1 1 0.32 0.22 0.07
37 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
38 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
39 INT285978 Negative_regulation of Gene_expression of Mapk8ip1 1 0.01 0.66 0.04
40 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0
41 INT154149 Positive_regulation of Gene_expression of TP73 3 0.18 0.67 0
42 INT203874 Positive_regulation of Gene_expression of GSTP1 3 0.49 1.91 0
43 INT234016 Gene_expression of PDCD4 2 0.32 3.13 0
44 INT154146 Regulation of Gene_expression of TP73 1 0.16 0.26 0
45 INT305470 Regulation of Gene_expression of GSTP1 1 0.06 0.59 0
46 INT203877 Phosphorylation of GSTP1 1 0.79 0.22 0
47 INT154152 Negative_regulation of TP73 1 0.13 0.21 0
48 INT199764 Positive_regulation of Gene_expression of Gstp1 1 0.55 2.21 0
49 INT315189 Binding of SFRP1 1 0.15 2.96 0
50 INT226287 Regulation of Gene_expression of SFRP1 1 0.38 0.37 0
51 INT203870 Negative_regulation of Binding of GSTP1 1 0.42 0.22 0
52 INT268549 Localization of PDCD4 1 0.30 1.17 0
53 INT268564 Positive_regulation of Gene_expression of PDCD4 1 0.28 1.12 0
54 INT226286 Negative_regulation of Gene_expression of SFRP1 1 0.31 0.7 0
55 INT268591 Binding of PDCD4 1 0.15 1.06 0
56 INT294017 Negative_regulation of Localization of SFRP1 1 0.32 0.47 0
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