GO:0043525

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Name positive regulation of neuron apoptosis
Categary Process
Go Slim No
Go Link GO:0043525
Unique Molecular Interactions 2597
Total Molecular Interactions 3478
Total Single Events 32447
Pain Genes Associated 83

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of neuron apoptosis. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of neuron apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
3 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
4 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
5 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
6 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
7 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
8 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
9 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
10 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
11 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
12 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
13 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
14 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
15 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
16 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
17 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
18 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
19 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
20 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
21 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
22 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
23 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
24 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
25 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
26 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
27 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
28 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
29 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
30 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
31 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
32 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
33 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
34 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
35 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
36 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
37 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
38 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
39 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
40 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
41 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
42 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
43 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
44 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
45 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
46 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
47 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
48 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
49 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
50 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
51 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
52 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
53 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
54 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
55 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
56 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
57 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
58 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
59 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
60 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
61 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
62 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
63 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
64 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
65 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
66 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
67 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
68 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
69 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
70 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
71 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
72 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
73 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
74 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
75 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
76 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
77 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
78 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
79 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
80 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
81 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
82 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
83 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
84 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
85 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
86 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
87 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
88 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
89 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
90 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2
91 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
92 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
93 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
94 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
95 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
96 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
97 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
98 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
99 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
100 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
101 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
102 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
103 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
104 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
105 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
106 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
107 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
108 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
109 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
110 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
111 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
112 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
113 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
114 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
115 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
116 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
117 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
118 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
119 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
120 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
121 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
122 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
123 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
124 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
125 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
126 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
127 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
128 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
129 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
130 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
131 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
132 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
133 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
134 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
135 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
136 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
137 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
138 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
139 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
140 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
141 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
142 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
143 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
144 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
145 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
146 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
147 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
148 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
149 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
150 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
151 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
152 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
153 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
154 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
155 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
156 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
157 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
158 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
159 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
160 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
161 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
162 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
163 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
164 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
165 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
166 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
167 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
168 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
169 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
170 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
171 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
172 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
173 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
174 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
175 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
176 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
177 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
178 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
179 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
180 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
181 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
182 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
183 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
184 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
185 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
186 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
187 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
188 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
189 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
190 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
191 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
192 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
193 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
194 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
195 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
196 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
197 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
198 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
199 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
200 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of neuron apoptosis. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of neuron apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
10 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
11 INT9660 Regulation of TNF 363 0.62 312.94 139.99
12 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
13 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
14 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
15 INT10166 Localization of Tnf 237 0.81 153.95 88.64
16 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
17 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
18 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
19 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
20 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
21 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
22 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
23 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
24 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
25 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
26 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
27 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
28 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
29 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
30 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
31 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
32 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
33 INT13354 Transcription of TNF 108 0.72 85.81 42.32
34 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
35 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
36 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
37 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
38 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
39 INT35406 Localization of Tnf 94 0.81 64.63 31.65
40 INT47764 Binding of Jun 106 0.48 22.62 31.39
41 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
42 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
43 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
44 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
45 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
46 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
47 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
48 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
49 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
50 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
51 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
52 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
53 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
54 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
55 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
56 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
57 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
58 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
59 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
60 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
61 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
62 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
63 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
64 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
65 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
66 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
67 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
68 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48
69 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
70 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
71 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
72 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
73 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
74 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
75 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
76 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
77 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
78 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
79 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
80 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
81 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
82 INT17593 Regulation of Jun 37 0.60 5.5 14.35
83 INT10173 Binding of Tnf 45 0.48 35.6 14.32
84 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
85 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
86 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
87 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3
88 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
89 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
90 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
91 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
92 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
93 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
94 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
95 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
96 INT52233 Transcription of Jun 37 0.66 6.39 11.15
97 INT10384 Positive_regulation of Nqo1 62 0.70 14.27 11.08
98 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
99 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
100 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
101 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
102 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
103 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
104 INT41627 Gene_expression of Nqo1 33 0.65 4.58 10.48
105 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
106 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
107 INT60198 Binding of JUN 54 0.48 11.56 10.27
108 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
109 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
110 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
111 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
112 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
113 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
114 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
115 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
116 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
117 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
118 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
119 INT61264 Regulation of Jun 36 0.61 18.42 8.71
120 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7
121 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
122 INT64815 Binding of Jun 49 0.48 21.47 8.59
123 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
124 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
125 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
126 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
127 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
128 INT88919 Positive_regulation of Casp9 39 0.70 28.64 8.18
129 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
130 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
131 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
132 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
133 INT98178 Localization of Casp3 32 0.65 21.01 7.77
134 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
135 INT64816 Transcription of Jun 31 0.69 16.01 7.64
136 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
137 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
138 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
139 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
140 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
141 INT68299 Binding of Tnf 17 0.39 12.55 7.49
142 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
143 INT10344 Localization of Jun 23 0.73 6.36 7.46
144 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
145 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
146 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
147 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
148 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
149 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
150 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
151 INT75497 Regulation of JUN 28 0.61 11.04 7.09
152 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
153 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
154 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
155 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92
156 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
157 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
158 INT140170 Binding of Nqo1 24 0.38 36.16 6.79
159 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
160 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
161 INT91721 Binding of IL18 21 0.48 21.17 6.56
162 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
163 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
164 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
165 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
166 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
167 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
168 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
169 INT57232 Binding of Casp3 22 0.36 9.42 6.2
170 INT73382 Regulation of Nqo1 13 0.58 1.58 6.16
171 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
172 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
173 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01
174 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
175 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
176 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
177 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
178 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
179 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
180 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
181 INT84704 Positive_regulation of Nqo1 18 0.70 18.64 5.65
182 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
183 INT124705 Binding of Il18 29 0.47 19.02 5.59
184 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
185 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
186 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
187 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
188 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
189 INT145929 Regulation of Bax 20 0.60 18.12 5.35
190 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33
191 INT60585 Regulation of TP53 59 0.59 54.55 5.21
192 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
193 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
194 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
195 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
196 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
197 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
198 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
199 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
200 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
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