GO:0043552

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Name positive regulation of phosphatidylinositol 3-kinase activity
Categary Process
Go Slim No
Go Link GO:0043552
Unique Molecular Interactions 731
Total Molecular Interactions 989
Total Single Events 7381
Pain Genes Associated 52

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of phosphatidylinositol 3-kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of phosphatidylinositol 3-kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
2 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
3 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
4 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
5 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
6 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
7 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
8 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
9 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
10 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
11 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
12 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
13 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
14 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
15 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
16 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
17 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
18 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
19 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
20 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
21 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
22 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
23 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
24 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
25 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
26 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
27 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
28 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
29 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
30 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
31 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
32 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
33 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
34 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
35 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
36 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86
37 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
38 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
39 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84
40 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84
41 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
42 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
43 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
44 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
45 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
46 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
47 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
48 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
49 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
50 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
51 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
52 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
53 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
54 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
55 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
56 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
57 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
58 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
59 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
60 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
61 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
62 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
63 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
64 INT224726 Negative_regulation of Binding of Fgf2 and Cia1 1 0.01 0.92 0.62
65 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
66 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
67 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
68 INT224727 Binding of Fgf2 and Cia1 1 0.01 0.91 0.61
69 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
70 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
71 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
72 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
73 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
74 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
75 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
76 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
77 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
78 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
79 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
80 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
81 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
82 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 0.12 0.09 0.5
83 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
84 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5
85 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
86 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
87 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
88 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
89 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
90 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
91 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
92 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
93 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
94 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
95 INT237154 LGALS4 Positive_regulation of KIT 1 0.10 1.99 0.47
96 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
97 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
98 INT280614 Il6 Regulation of Transcription of Irs1 1 0.26 0.4 0.46
99 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
100 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
101 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
102 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
103 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
104 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
105 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44
106 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
107 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
108 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
109 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
110 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
111 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
112 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
113 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
114 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
115 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
116 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
117 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38
118 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38
119 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
120 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
121 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
122 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
123 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
124 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
125 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
126 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
127 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
128 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
129 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
130 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
131 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
132 INT252292 CCL21 Regulation of Binding of Mthfd1 1 0.03 0.41 0.33
133 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
134 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
135 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33
136 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
137 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
138 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
139 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
140 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
141 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
142 INT7417 Calca Positive_regulation of Localization of FGFR3 1 0.03 0.09 0.3
143 INT7405 CALCA Negative_regulation of FGFR3 1 0.00 0.1 0.3
144 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
145 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
146 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
147 INT7419 Calca Regulation of Localization of FGFR3 1 0.02 0.09 0.3
148 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
149 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
150 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
151 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
152 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
153 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
154 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
155 INT246841 Binding of Irs1 and Ppp1r13b 5 0.16 0.94 0.28
156 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
157 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
158 INT56091 FGF2 Positive_regulation of Transcription of SERPINE1 1 0.43 0.41 0.28
159 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
160 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
161 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
162 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
163 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
164 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
165 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
166 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
167 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
168 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
169 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
170 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
171 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
172 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
173 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
174 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
175 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
176 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
177 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22
178 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
179 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
180 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
181 INT237201 Cd3e Positive_regulation of KIT 1 0.03 0 0.21
182 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
183 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
184 INT355103 Binding of Ins2 and Ins1 1 0.12 2 0.21
185 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
186 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
187 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
188 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
189 INT260827 Binding of Flt1 and Pgf 1 0.27 0.6 0.2
190 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
191 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
192 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
193 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
194 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
195 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
196 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
197 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
198 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
199 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
200 INT280621 Il6 Negative_regulation of Transcription of Irs1 1 0.25 0.4 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of phosphatidylinositol 3-kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of phosphatidylinositol 3-kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
3 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
4 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
5 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
6 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
7 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
8 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
9 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
10 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
11 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
12 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
13 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
14 INT27627 Binding of Rac1 41 0.41 22.88 13.68
15 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
16 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
17 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
18 INT7411 Localization of FGFR3 40 0.78 4.77 10.24
19 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
20 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
21 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
22 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
23 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
24 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12
25 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48
26 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41
27 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
28 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
29 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
30 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2
31 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
32 INT100222 Binding of Src 9 0.26 5.41 5.37
33 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
34 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18
35 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17
36 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
37 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
38 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
39 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
40 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
41 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
42 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
43 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
44 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24
45 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
46 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
47 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11
48 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
49 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
50 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
51 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
52 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
53 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
54 INT122327 Regulation of Src 6 0.59 0.59 3.6
55 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
56 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
57 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
58 INT207570 Phosphorylation of IRS1 45 0.71 33.27 3.42
59 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
60 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
61 INT7408 Negative_regulation of FGFR3 12 0.43 2.38 3.33
62 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
63 INT168003 Localization of Fgf2 24 0.80 12.52 3.31
64 INT106341 Phosphorylation of Irs1 18 0.72 14.7 3.3
65 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
66 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24
67 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
68 INT58475 Localization of Rac1 12 0.75 5.94 3.2
69 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
70 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
71 INT101083 Binding of Fgf2 14 0.42 4.12 3.14
72 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
73 INT115317 Transcription of FGF2 14 0.62 12.79 3
74 INT174864 Positive_regulation of Transcription of FGF2 8 0.44 7.58 3
75 INT88810 Positive_regulation of Gene_expression of FGF2 17 0.50 12.62 2.98
76 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
77 INT65033 Negative_regulation of Fgf2 21 0.59 12.36 2.94
78 INT103910 Binding of NOD2 19 0.47 12.24 2.93
79 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
80 INT7409 Negative_regulation of Localization of FGFR3 12 0.37 2.24 2.92
81 INT106340 Positive_regulation of Phosphorylation of Irs1 8 0.53 7.03 2.85
82 INT126514 Positive_regulation of CCR7 16 0.43 16.21 2.79
83 INT53733 Positive_regulation of FGFR3 6 0.45 1.32 2.76
84 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
85 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
86 INT64688 Negative_regulation of Gene_expression of Fgf2 5 0.59 5.07 2.56
87 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
88 INT182224 Binding of CCL21 6 0.34 5.91 2.54
89 INT24672 Localization of FGF2 27 0.71 14.59 2.48
90 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
91 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
92 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45
93 INT7410 Positive_regulation of Localization of FGFR3 9 0.45 1.97 2.36
94 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
95 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
96 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
97 INT36314 Gene_expression of FGFR3 11 0.73 6.21 2.23
98 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
99 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
100 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17
101 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15
102 INT97898 Regulation of FGF2 8 0.60 3.85 2.09
103 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
104 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08
105 INT87436 Regulation of Fgf2 6 0.45 3.95 2.03
106 INT100371 Positive_regulation of Flt1 11 0.63 6.42 2.02
107 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01
108 INT237322 Gene_expression of Irs1 52 0.77 21.07 2
109 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97
110 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
111 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92
112 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
113 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
114 INT64687 Regulation of Gene_expression of Fgf2 7 0.62 2.29 1.89
115 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
116 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
117 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
118 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
119 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
120 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
121 INT92677 Positive_regulation of Gene_expression of Fgf2 11 0.69 4.25 1.68
122 INT177509 Regulation of CCL21 6 0.45 5.43 1.66
123 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
124 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
125 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
126 INT255663 Binding of Flt1 11 0.32 6.92 1.64
127 INT230799 Positive_regulation of Phosphorylation of Irs1 28 0.69 11.17 1.63
128 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
129 INT221059 Negative_regulation of CCL21 5 0.28 2.48 1.58
130 INT145921 Localization of CCL21 4 0.73 2.41 1.58
131 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
132 INT240031 Positive_regulation of Phosphorylation of IRS1 15 0.46 13.17 1.53
133 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
134 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
135 INT122547 Positive_regulation of Positive_regulation of FGF2 3 0.44 3.1 1.49
136 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
137 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48
138 INT98455 Regulation of Src 4 0.20 1.76 1.48
139 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
140 INT53735 Regulation of FGFR3 4 0.26 0.76 1.45
141 INT33299 Binding of CCR7 3 0.31 2.88 1.45
142 INT24671 Binding of FGF2 14 0.35 8.73 1.43
143 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
144 INT237409 Localization of Erbb4 3 0.57 1.31 1.41
145 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
146 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37
147 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37
148 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
149 INT240842 Positive_regulation of Gene_expression of Irs1 31 0.69 12 1.31
150 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
151 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
152 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
153 INT120970 Negative_regulation of Irs1 12 0.37 8.65 1.28
154 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
155 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26
156 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
157 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
158 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
159 INT174866 Regulation of Gene_expression of FGF2 4 0.39 7.13 1.2
160 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
161 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
162 INT31572 Negative_regulation of FLT1 21 0.48 16.49 1.18
163 INT87346 Binding of PTK2 6 0.37 4.03 1.18
164 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
165 INT181400 Negative_regulation of Ccl19 3 0.43 1.97 1.13
166 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
167 INT134627 Positive_regulation of Gene_expression of Flt1 9 0.49 7.16 1.12
168 INT81235 Regulation of Localization of FGFR3 2 0.26 0 1.12
169 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
170 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
171 INT147407 Protein_catabolism of FGF2 1 0.91 0.33 1.06
172 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
173 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
174 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
175 INT145864 Gene_expression of Irs1 5 0.71 3.34 1.01
176 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
177 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
178 INT181367 Negative_regulation of Ccl21b 1 0.01 1.72 0.98
179 INT317504 Protein_catabolism of Src 1 0.49 0.13 0.97
180 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
181 INT184236 Positive_regulation of Localization of Fgf2 1 0.27 2.23 0.95
182 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
183 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
184 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
185 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91
186 INT149383 Binding of Lyn 1 0.36 1.14 0.91
187 INT182239 Negative_regulation of Gene_expression of CCR7 1 0.36 1.16 0.91
188 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
189 INT184687 Transcription of Ccl19 1 0.68 1.04 0.9
190 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
191 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
192 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
193 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
194 INT240849 Negative_regulation of Phosphorylation of Irs1 11 0.43 4.74 0.85
195 INT178498 Negative_regulation of Fgf2 11 0.42 4.21 0.84
196 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
197 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
198 INT167833 Positive_regulation of Ins2 4 0.50 6.52 0.82
199 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
200 INT89407 Positive_regulation of IRS1 10 0.51 9.67 0.81
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