GO:0043566

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Name structure-specific DNA binding
Categary Function
Go Slim No
Go Link GO:0043566
Unique Molecular Interactions 10
Total Molecular Interactions 13
Total Single Events 103
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for structure-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for structure-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128677 Positive_regulation of Binding of TET1 and Tet2 1 0.26 0.8 0.33
2 INT128678 Binding of TET1 and Tet2 1 0.19 0.8 0.33
3 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0
4 INT285772 ERCC1 Positive_regulation of Binding of RAD51 1 0.05 0 0
5 INT285771 ERCC1 Regulation of Binding of RAD51 1 0.05 0 0
6 INT277136 Ebp Positive_regulation of Gene_expression of Mlh1 1 0.01 1.45 0
7 INT190049 Binding of Mlh1 and Msh3 1 0.24 0.22 0
8 INT190048 Binding of Mlh1 and Msh2 1 0.31 0.22 0
9 INT276759 ABCB1 Regulation of TOP2A 1 0.04 0.61 0
10 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for structure-specific DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in structure-specific DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128670 Binding of TET1 10 0.42 3.96 1.63
2 INT39931 Negative_regulation of TET1 1 0.37 0 0.44
3 INT219001 Gene_expression of ERCC1 12 0.54 3.77 0.38
4 INT11327 Positive_regulation of TET1 1 0.67 0.23 0.27
5 INT184997 Gene_expression of TOP2A 6 0.63 1.65 0.15
6 INT285813 Negative_regulation of ERCC1 13 0.30 2.03 0.08
7 INT244340 Localization of TET1 1 0.61 0.33 0.08
8 INT268846 Negative_regulation of Top2a 6 0.29 3.06 0.07
9 INT258473 Binding of TOP2A 3 0.05 1.65 0.05
10 INT190022 Positive_regulation of Mlh1 2 0.38 3.16 0.03
11 INT235686 Gene_expression of Top2a 5 0.60 4.34 0
12 INT118827 Regulation of TOP2A 4 0.04 1.75 0
13 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0
14 INT190039 Gene_expression of Mlh1 3 0.68 6.14 0
15 INT190038 Binding of Mlh1 2 0.28 3.11 0
16 INT268847 Binding of Top2a 2 0.24 0.6 0
17 INT211582 Transcription of Mlh1 1 0.41 0.34 0
18 INT285815 Binding of ERCC1 1 0.26 0 0
19 INT190012 Regulation of Mlh1 1 0.34 0.34 0
20 INT308260 Positive_regulation of TOP2A 1 0.03 0.58 0
21 INT256916 Regulation of Gene_expression of Top2a 1 0.47 1.2 0
22 INT285814 Positive_regulation of ERCC1 1 0.35 0.14 0
23 INT350584 Negative_regulation of Gene_expression of Mlh1 1 0.51 2.21 0
24 INT239664 Positive_regulation of Gene_expression of TOP2A 1 0.01 0.1 0
25 INT256921 Regulation of Top2a 1 0.21 1.28 0
26 INT268845 Positive_regulation of Binding of Top2a 1 0.05 0.33 0
27 INT285819 Negative_regulation of Negative_regulation of ERCC1 1 0.30 0.18 0
28 INT211583 Regulation of Transcription of Mlh1 1 0.27 0.34 0
29 INT273508 Negative_regulation of Gene_expression of Top2a 1 0.21 0.17 0
30 INT350588 Negative_regulation of Mlh1 1 0.38 3.05 0
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