GO:0043568

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Name positive regulation of insulin-like growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0043568
Unique Molecular Interactions 868
Total Molecular Interactions 1390
Total Single Events 14180
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of insulin-like growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of insulin-like growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
3 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
4 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
5 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
6 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
7 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
8 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
9 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
10 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
11 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
12 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
13 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
14 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
15 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
16 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
17 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
18 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
19 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
20 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
21 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
22 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
23 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
24 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
25 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
26 INT48117 GH1 Positive_regulation of CGA 1 0.10 0 1.28
27 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
28 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24
29 INT32480 Gh1 Positive_regulation of Gene_expression of Ghrh 1 0.35 0 1.15
30 INT32182 PRL Regulation of GHRH 2 0.17 0 1.12
31 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 0.05 0 1.12
32 INT19887 GHRH Positive_regulation of Positive_regulation of GH1 2 0.56 0.3 1.08
33 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
34 INT33338 Adarb1 Positive_regulation of Localization of Gh1 1 0.04 0 1.08
35 INT33336 Adarb1 Positive_regulation of Negative_regulation of Gh1 1 0.03 0 1.08
36 INT33337 Adarb1 Positive_regulation of Gh1 1 0.03 0 1.08
37 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
38 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
39 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99
40 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
41 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98
42 INT19758 Ghrh Positive_regulation of Positive_regulation of Gh 1 0.26 0 0.98
43 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
44 INT140068 Binding of GH1 and Ghsr 1 0.00 0.47 0.97
45 INT36682 Gh1 Regulation of Gene_expression of Gnrhr 2 0.08 0 0.96
46 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95
47 INT31108 Ghrh Negative_regulation of Gh1 2 0.55 0 0.95
48 INT62106 Ghrh Negative_regulation of Localization of Gh 1 0.06 0 0.94
49 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 0.06 0 0.94
50 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 0.49 0 0.93
51 INT39201 Olr824 Positive_regulation of Localization of Gh1 1 0.03 0 0.91
52 INT48113 GH1 Positive_regulation of Localization of CGA 1 0.07 0 0.9
53 INT30411 Ghrh Regulation of Gene_expression of Gh1 1 0.40 0.12 0.9
54 INT35160 GH1 Regulation of PRL 2 0.37 0 0.89
55 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
56 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
57 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88
58 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
59 INT44589 Negative_regulation of Oprl1 Positive_regulation of Gh1 1 0.22 0.53 0.87
60 INT44590 Oprl1 Positive_regulation of Gh1 1 0.23 0.53 0.87
61 INT40742 Pomc Regulation of Localization of Gh1 1 0.37 0 0.86
62 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84
63 INT105970 GH1 Regulation of Ghsr 1 0.04 1.16 0.84
64 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
65 INT5103 Gal Regulation of Localization of Gh1 1 0.33 0.08 0.82
66 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81
67 INT90382 Binding of CRH and GH1 1 0.34 0.05 0.81
68 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81
69 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
70 INT40743 Binding of Gh1 and Pomc 1 0.22 0 0.8
71 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
72 INT105250 Cyb5b Regulation of Localization of Gh1 1 0.00 0 0.79
73 INT92793 Gh Positive_regulation of CTS 1 0.04 1.39 0.78
74 INT295546 Ghrl Positive_regulation of Ghsr 3 0.39 0.09 0.77
75 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
76 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
77 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
78 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
79 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
80 INT353718 Binding of Rbm39 and Ghsr 1 0.01 0 0.76
81 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75
82 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75
83 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75
84 INT54802 SST Negative_regulation of Localization of Gh 1 0.01 0 0.75
85 INT54801 SST Negative_regulation of Positive_regulation of Gh 1 0.01 0 0.75
86 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
87 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73
88 INT16894 Regulation of GHRH Regulation of GH1 2 0.37 0 0.72
89 INT14196 Glra2 Positive_regulation of Localization of Gh1 1 0.06 0 0.71
90 INT31307 Ghrh Regulation of Gh1 3 0.27 1.36 0.7
91 INT30125 Binding of Gh and Ghrh 2 0.06 0.36 0.7
92 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
93 INT784 Prss12 Positive_regulation of Gh1 1 0.06 0 0.7
94 INT20688 Adra2a Regulation of Localization of Gh1 1 0.26 0.37 0.7
95 INT30409 Negative_regulation of Negative_regulation of Positive_regulation of Gh1 1 0.02 0.1 0.7
96 INT30408 Negative_regulation of Negative_regulation of Gh1 1 0.02 0.1 0.7
97 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
98 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
99 INT47264 Abat Regulation of Localization of Gh1 1 0.14 0 0.67
100 INT40471 GH1 Positive_regulation of POMC 1 0.25 0 0.67
101 INT40470 GH1 Positive_regulation of GHRH 1 0.06 0 0.67
102 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67
103 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
104 INT31260 Sst Negative_regulation of Gh1 2 0.11 0 0.66
105 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
106 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
107 INT142209 Adcyap1 Positive_regulation of Gene_expression of Gh 1 0.05 0 0.63
108 INT30502 Negative_regulation of OPRM1 Negative_regulation of Gh 1 0.00 0 0.63
109 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62
110 INT15731 SST Regulation of Gh 1 0.04 0 0.62
111 INT19011 Binding of Ghrh and Ghsr 1 0.40 0 0.62
112 INT61507 Ghrhr Positive_regulation of Localization of Gh1 1 0.41 0 0.61
113 INT56520 DDX21 Positive_regulation of Localization of Gh 1 0.11 0.16 0.6
114 INT75040 Binding of GHSR and MC1R 1 0.02 0.34 0.6
115 INT56391 Pomc Negative_regulation of Localization of Gh1 1 0.26 0 0.59
116 INT43692 Cyp3a23/3a1 Negative_regulation of Gh1 1 0.04 0 0.59
117 INT30462 Gnrhr Positive_regulation of Localization of Gh1 2 0.21 0.08 0.58
118 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58
119 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
120 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
121 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
122 INT18405 GHRH Positive_regulation of Regulation of SST 1 0.56 0 0.57
123 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
124 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
125 INT32484 Gnrhr Regulation of GHRH 1 0.01 0 0.55
126 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
127 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
128 INT69566 Positive_regulation of Ghrh Regulation of Gh 1 0.04 1.66 0.55
129 INT32478 Gh1 Regulation of Gene_expression of Ghrh 1 0.28 0 0.55
130 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54
131 INT84067 IGFBP1 Regulation of GH1 1 0.02 1.18 0.54
132 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
133 INT142206 Negative_regulation of Adcyap1 Positive_regulation of Gh 1 0.04 0 0.54
134 INT34368 TRH Positive_regulation of GHRH 1 0.23 0.4 0.53
135 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
136 INT33513 GH1 Positive_regulation of PRL 1 0.30 0 0.53
137 INT49696 Trh Regulation of GH1 2 0.02 0.22 0.52
138 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
139 INT105971 GH1 Regulation of Ghrl 1 0.03 0.75 0.52
140 INT24869 GAL Regulation of Localization of Gh 1 0.19 0.4 0.51
141 INT32479 Gh1 Negative_regulation of Dbi 1 0.01 0 0.51
142 INT24205 Gh1 Negative_regulation of Gal 1 0.34 0 0.51
143 INT56671 Negative_regulation of Ghrh Positive_regulation of Gh1 1 0.40 0 0.49
144 INT140067 GH1 Positive_regulation of Ghsr 1 0.00 0.23 0.49
145 INT46051 ABAT Regulation of Localization of GH1 1 0.19 0 0.49
146 INT70930 Sstr2 Regulation of Localization of Gh1 1 0.15 0 0.49
147 INT67984 GHRH Regulation of PRL 1 0.22 0 0.49
148 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48
149 INT48114 GHRH Positive_regulation of Localization of CGB 1 0.05 0 0.48
150 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
151 INT55020 Gh1 Regulation of Gene_expression of Prl 1 0.19 0 0.48
152 INT140066 Ghsr Positive_regulation of GH1 1 0.00 0.23 0.48
153 INT67983 Positive_regulation of HTR1B Positive_regulation of Localization of GHRH 1 0.42 0 0.47
154 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
155 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
156 INT101003 GHRH Regulation of Localization of GGH 1 0.29 0 0.47
157 INT47222 Binding of Gh and Prl 1 0.22 0.18 0.46
158 INT72203 GH1 Regulation of OGG1 1 0.10 0 0.46
159 INT47221 Prl Regulation of Localization of Gh 1 0.28 0.27 0.46
160 INT30412 Sst Regulation of Gene_expression of Gh1 1 0.19 0.06 0.45
161 INT48116 Negative_regulation of GH1 Positive_regulation of CGA 1 0.06 0 0.45
162 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
163 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
164 INT8181 Grm5 Positive_regulation of Gh 1 0.00 0 0.44
165 INT29254 Positive_regulation of ADRA2C Positive_regulation of Localization of GH1 1 0.13 0.06 0.44
166 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43
167 INT122237 Gnrh1 Positive_regulation of Gh1 1 0.20 0 0.43
168 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43
169 INT40446 Cck Regulation of Gh1 1 0.36 0 0.43
170 INT86972 PDE1B Positive_regulation of Localization of Gh 1 0.00 0 0.42
171 INT64069 Sst Regulation of Localization of Gh1 1 0.10 0.1 0.42
172 INT3571 Sst Regulation of Negative_regulation of Gh1 1 0.24 0 0.42
173 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
174 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
175 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
176 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41
177 INT250531 Ghrh Regulation of Gh 1 0.22 0 0.41
178 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
179 INT16302 GHRH Regulation of Localization of GH1 1 0.65 0.62 0.4
180 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
181 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
182 INT62107 Ghrh Negative_regulation of Regulation of Gh 1 0.06 0 0.39
183 INT36812 Olr824 Positive_regulation of Gh1 1 0.04 0 0.39
184 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
185 INT67553 Ghrh Positive_regulation of Regulation of Gh 1 0.04 0.55 0.39
186 INT62110 SLC25A4 Negative_regulation of Regulation of Gh 1 0.06 0 0.39
187 INT36814 Olr824 Regulation of Gh1 1 0.02 0 0.39
188 INT3634 Trh Regulation of Gh1 3 0.20 0.23 0.38
189 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38
190 INT48115 GH1 Positive_regulation of CGB 1 0.06 0 0.38
191 INT30501 Sst Negative_regulation of Localization of Gh 1 0.01 0 0.38
192 INT182497 IL1B Regulation of Localization of GH1 1 0.00 0.84 0.38
193 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
194 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
195 INT8331 OPRD1 Regulation of Localization of GHRH 1 0.18 0.18 0.37
196 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
197 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36
198 INT16896 GHSR Regulation of GH1 2 0.23 0.24 0.36
199 INT35363 Binding of GH1 and GHRH 2 0.36 0.94 0.36
200 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of insulin-like growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of insulin-like growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT876 Localization of Gh1 843 0.80 67.75 340.82
2 INT1893 Localization of Gh 1041 0.79 340.23 256.58
3 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
4 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
5 INT252 Localization of GH1 529 0.80 227.4 122.05
6 INT1530 Regulation of Gh 382 0.61 115.96 112.47
7 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
8 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
9 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
10 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
11 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
12 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
13 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
14 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
15 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
16 INT1782 Regulation of Gh1 125 0.62 22 55.74
17 INT249 Localization of GHRH 215 0.80 78.02 51.87
18 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
19 INT921 Regulation of GH1 172 0.60 52.88 51.04
20 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
21 INT531 Gene_expression of GH1 376 0.75 193.45 46.24
22 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
23 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52
24 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3
25 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
26 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92
27 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
28 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39
29 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
30 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
31 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
32 INT250 Regulation of GHRH 65 0.61 17.46 23.19
33 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15
34 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74
35 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
36 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
37 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49
38 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96
39 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51
40 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
41 INT4242 Negative_regulation of Positive_regulation of Gh1 26 0.58 1.47 15.75
42 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
43 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32
44 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
45 INT9678 Positive_regulation of Positive_regulation of GH1 32 0.68 8.14 12.97
46 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
47 INT254 Regulation of Localization of GHRH 30 0.60 5.17 11.46
48 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34
49 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
50 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16
51 INT35366 Binding of AR 87 0.47 30.52 8.9
52 INT34777 Localization of IGF1 82 0.80 42.68 8.62
53 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28
54 INT953 Positive_regulation of Positive_regulation of GHRH 17 0.67 2.38 8.18
55 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
56 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86
57 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8
58 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31
59 INT878 Regulation of Gene_expression of Gh1 13 0.43 1.13 6.98
60 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
61 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
62 INT28861 Binding of Gh 61 0.46 25.61 6.38
63 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
64 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
65 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
66 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
67 INT9683 Binding of GH1 57 0.47 21.14 5.99
68 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93
69 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
70 INT3614 Negative_regulation of Gene_expression of Gh1 16 0.42 6.8 5.74
71 INT151032 Localization of Igf1 49 0.76 26.32 5.71
72 INT13735 Negative_regulation of Regulation of GH1 14 0.42 4.35 5.39
73 INT18661 Localization of Ghsr 32 0.78 3.19 5.2
74 INT99091 Regulation of AR 70 0.45 31.68 5.05
75 INT19900 Binding of GHRH 22 0.37 5.75 5
76 INT4611 Transcription of Gh1 12 0.68 1.04 4.97
77 INT5205 Localization of AR 43 0.80 12.87 4.63
78 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
79 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61
80 INT149091 Gene_expression of Ghsr 42 0.76 5.11 4.6
81 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
82 INT16220 Negative_regulation of Regulation of Gh 13 0.42 3.59 4.33
83 INT49360 Localization of Igf1 22 0.76 6.96 4.26
84 INT16304 Negative_regulation of Positive_regulation of GHRH 9 0.51 2.56 4.25
85 INT10842 Transcription of Gh 18 0.64 2.94 4.13
86 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88
87 INT11605 Regulation of Positive_regulation of Gh 10 0.45 2.08 3.85
88 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
89 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68
90 INT7365 Binding of Gh1 17 0.37 2.83 3.54
91 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
92 INT20179 Positive_regulation of Regulation of Gh 12 0.54 3.99 3.42
93 INT18407 Regulation of Regulation of GH1 6 0.44 0.14 3.37
94 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
95 INT986 Negative_regulation of Localization of GHRH 16 0.58 8.57 3.16
96 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
97 INT13272 Regulation of Positive_regulation of Gh1 4 0.44 0.35 3.02
98 INT16130 Binding of IGF1 67 0.48 27.43 2.95
99 INT19009 Positive_regulation of Ghsr 17 0.64 5.71 2.78
100 INT919 Regulation of Positive_regulation of GH1 7 0.47 1.09 2.75
101 INT53906 Positive_regulation of Negative_regulation of Gh 9 0.50 6.72 2.73
102 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
103 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
104 INT66544 Binding of Igf1 23 0.46 8.33 2.44
105 INT20410 Regulation of Regulation of Gh1 5 0.30 0.66 2.36
106 INT35210 Gene_expression of Ghsr 39 0.75 6 2.24
107 INT4610 Negative_regulation of Transcription of Gh1 4 0.42 0.51 2.17
108 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
109 INT323480 Negative_regulation of Ghsr 4 0.36 0.9 2.06
110 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
111 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
112 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
113 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
114 INT1780 Regulation of Negative_regulation of Gh1 3 0.49 0.09 1.8
115 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
116 INT45719 Positive_regulation of Transcription of Gh 5 0.47 0.68 1.66
117 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
118 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63
119 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
120 INT19007 Binding of Ghsr 5 0.46 0.46 1.6
121 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
122 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
123 INT16528 Positive_regulation of Regulation of Gh1 5 0.48 0.37 1.47
124 INT43264 Transcription of GHRH 5 0.59 0.4 1.42
125 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
126 INT61068 Gene_expression of Igfbp3 15 0.75 8.48 1.41
127 INT65892 Negative_regulation of Binding of Gh 8 0.32 3.61 1.38
128 INT90491 Binding of Igf1 25 0.44 9.75 1.36
129 INT82932 Transcription of AR 14 0.67 5.75 1.34
130 INT47102 Regulation of Binding of GHRH 2 0.28 0 1.34
131 INT68500 Regulation of Ar 6 0.27 4.16 1.32
132 INT58421 Positive_regulation of Transcription of GHRH 1 0.43 0.38 1.32
133 INT8334 Regulation of Positive_regulation of GHRH 3 0.43 0.7 1.27
134 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
135 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
136 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
137 INT25432 Negative_regulation of Gene_expression of GHRH 6 0.37 2.9 1.12
138 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
139 INT57852 Regulation of Ghsr 15 0.59 1.02 1.1
140 INT47495 Protein_catabolism of Gh 2 0.98 0.68 1.08
141 INT142205 Negative_regulation of Transcription of Gh 1 0.16 0 1.08
142 INT149090 Positive_regulation of Ghsr 10 0.70 2.33 1.06
143 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
144 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
145 INT209679 Positive_regulation of Regulation of AR 3 0.37 1.88 0.96
146 INT62246 Positive_regulation of Transcription of Gh1 1 0.26 0 0.94
147 INT13732 Negative_regulation of Regulation of GHRH 3 0.43 0.84 0.93
148 INT16898 Localization of GHSR 8 0.74 1.76 0.91
149 INT215202 Localization of Igfbp3 3 0.62 2.5 0.91
150 INT75050 Binding of GHSR 3 0.47 0.64 0.89
151 INT353715 Negative_regulation of Gene_expression of Ghsr 1 0.35 0 0.89
152 INT55982 Negative_regulation of Negative_regulation of Gh 4 0.55 1.02 0.88
153 INT7867 Regulation of Negative_regulation of Gh 5 0.33 1.92 0.87
154 INT73784 Regulation of Binding of GH1 2 0.26 0.82 0.86
155 INT3560 Negative_regulation of Regulation of Gh1 5 0.40 2.44 0.85
156 INT132068 Gene_expression of Igfbp3 10 0.64 3.73 0.83
157 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
158 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
159 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
160 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
161 INT156529 Positive_regulation of Gene_expression of Ar 1 0.05 0.09 0.8
162 INT18406 Regulation of Regulation of GHRH 2 0.45 0.93 0.76
163 INT185669 Positive_regulation of Localization of AR 7 0.33 1.83 0.73
164 INT277652 Negative_regulation of Localization of Igfbp3 1 0.11 0.74 0.72
165 INT35208 Positive_regulation of Negative_regulation of Gh1 3 0.49 0.08 0.7
166 INT70362 Transcription of GH1 9 0.56 2.01 0.69
167 INT156060 Regulation of Binding of AR 2 0.09 0.42 0.69
168 INT295519 Localization of Ghsr 7 0.72 0.75 0.68
169 INT19891 Regulation of Gene_expression of GHRH 3 0.43 1.46 0.68
170 INT17698 Positive_regulation of Regulation of GH1 6 0.46 0.9 0.65
171 INT47563 Negative_regulation of Negative_regulation of Gh1 3 0.41 0.7 0.64
172 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
173 INT277647 Negative_regulation of Igfbp3 1 0.15 0.94 0.62
174 INT335991 Positive_regulation of Localization of Igfbp3 1 0.42 1.57 0.61
175 INT17493 Binding of Ar 14 0.48 3.62 0.6
176 INT106343 Positive_regulation of Positive_regulation of Igf1 2 0.69 1.45 0.59
177 INT49343 Positive_regulation of Ar 8 0.42 4.38 0.58
178 INT220365 Negative_regulation of Transcription of Igf1 3 0.45 1.28 0.56
179 INT277649 Localization of Igfbp3 1 0.20 0.69 0.55
180 INT63364 Positive_regulation of Igfbp3 9 0.64 1.92 0.53
181 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53
182 INT49362 Positive_regulation of Localization of Igf1 4 0.65 2.26 0.53
183 INT19005 Positive_regulation of Positive_regulation of Ghsr 1 0.49 0 0.53
184 INT224959 Positive_regulation of Gene_expression of Ghsr 5 0.45 1.09 0.5
185 INT132996 Positive_regulation of Gene_expression of Igfbp3 4 0.49 3.2 0.5
186 INT61067 Positive_regulation of Igfbp3 3 0.41 1.21 0.5
187 INT185513 Phosphorylation of Igf1 3 0.67 0.46 0.5
188 INT58420 Negative_regulation of Transcription of GHRH 1 0.37 0.13 0.45
189 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
190 INT140942 Regulation of Transcription of Igf1 3 0.32 1.37 0.43
191 INT87505 Positive_regulation of Binding of Gh 2 0.49 0 0.42
192 INT16897 Gene_expression of GHSR 6 0.77 0.46 0.41
193 INT58364 Positive_regulation of GHSR 2 0.56 0.35 0.39
194 INT104312 Positive_regulation of Transcription of AR 2 0.37 0.96 0.38
195 INT132995 Negative_regulation of Igfbp3 1 0.44 0.36 0.38
196 INT78447 Protein_catabolism of GH1 2 0.36 1.2 0.36
197 INT261774 Positive_regulation of Phosphorylation of Igf1 1 0.08 0.09 0.36
198 INT200198 Regulation of Localization of Igf1 6 0.58 4.51 0.34
199 INT216379 Positive_regulation of Gene_expression of WNT1 5 0.30 3.1 0.34
200 INT7359 Regulation of Binding of Gh1 1 0.33 0.13 0.34
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