GO:0043576

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Name regulation of respiratory gaseous exchange
Categary Process
Go Slim No
Go Link GO:0043576
Unique Molecular Interactions 115
Total Molecular Interactions 163
Total Single Events 2009
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of respiratory gaseous exchange. They are ordered first by their pain relevance and then by number of times they were reported for regulation of respiratory gaseous exchange. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
2 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
3 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
4 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
5 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
6 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
7 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
8 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
9 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
10 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
11 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
12 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
13 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
14 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
15 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
16 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
17 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
18 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
19 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
20 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
21 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
22 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
23 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
24 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
25 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
26 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
27 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
28 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
29 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
30 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
31 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
32 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
33 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
34 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
35 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
36 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
37 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
38 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
39 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
40 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
41 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
42 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
43 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
44 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
45 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
46 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
47 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
48 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
49 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
50 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
51 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54
52 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
53 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
54 INT283736 Tbs1 Positive_regulation of Grin1 1 0.04 0 0.48
55 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
56 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
57 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
58 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43
59 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
60 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
61 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
62 INT296300 Binding of Grin1 and Kcnip3 1 0.18 0 0.4
63 INT131180 Binding of Grin1 and Oprd1 1 0.24 0 0.39
64 INT121757 Grin1 Regulation of Gene_expression of Fos 1 0.44 0.44 0.35
65 INT13374 Binding of Grin1 and Ltp 1 0.20 0 0.35
66 INT121758 Grin1 Regulation of Positive_regulation of Fos 1 0.44 0.44 0.35
67 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
68 INT16382 Binding of Grin1 and Gnmt 1 0.04 0.17 0.32
69 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
70 INT99599 ZNF398 Negative_regulation of NR4A2 1 0.05 0.41 0.3
71 INT99600 ZNF398 Negative_regulation of Transcription of NR4A2 1 0.10 0.41 0.3
72 INT317571 Grin1 Regulation of Trpv1 1 0.00 0 0.29
73 INT317562 Binding of Grin1 and Gnptab 1 0.00 0 0.29
74 INT334666 Slc9a1 Positive_regulation of Grin1 1 0.09 0.09 0.27
75 INT310402 Binding of CALM1 and Grin1 1 0.00 0 0.26
76 INT149973 MC1R Positive_regulation of Gene_expression of NR4A2 1 0.44 0.32 0.23
77 INT201868 PASK Regulation of POU5F2 1 0.00 0.12 0.21
78 INT263765 Neto1 Regulation of Grin1 1 0.39 0.26 0.2
79 INT263721 Binding of Grin1 and Neto1 1 0.33 0 0.18
80 INT238087 Binding of Grin1 and Mmp3 1 0.13 0 0.15
81 INT273238 Grin1 Positive_regulation of Ptprs 1 0.07 0.51 0.14
82 INT201867 Binding of PGR and PASK 1 0.02 0.23 0.14
83 INT197317 Nr4a2 Regulation of Gene_expression of Th 1 0.03 0.07 0.12
84 INT260495 VEGFA Positive_regulation of Grin1 1 0.08 1.08 0.12
85 INT350343 Csnk2a2 Regulation of Grin1 1 0.11 0.09 0.11
86 INT231301 Prnp Regulation of Regulation of Grin1 1 0.26 0.24 0.08
87 INT263725 Neto1 Regulation of Localization of Grin1 1 0.39 0.15 0.08
88 INT263755 Grin1 Regulation of Localization of Grin2b 1 0.27 0.17 0.07
89 INT263782 Grin2a Regulation of Localization of Grin1 1 0.29 0.17 0.07
90 INT263761 Grin1 Regulation of Localization of Vamp2 1 0.27 0.17 0.07
91 INT263784 Dlg4 Regulation of Localization of Grin1 1 0.17 0.17 0.07
92 INT263748 Grin1 Regulation of Localization of Gria2 1 0.20 0.17 0.07
93 INT263728 Grin2b Regulation of Localization of Grin1 1 0.27 0.17 0.07
94 INT263759 Grin1 Regulation of Localization of Grin2a 1 0.29 0.17 0.07
95 INT263742 Grin1 Regulation of Localization of Dlg4 1 0.19 0.17 0.07
96 INT350345 Tbp Positive_regulation of Positive_regulation of Grin1 1 0.18 0 0.07
97 INT263770 Rasgrf1 Positive_regulation of Positive_regulation of Grin1 1 0.24 0 0.06
98 INT202893 Camk4 Negative_regulation of Grin1 1 0.10 0.17 0.05
99 INT263781 Localization of Neto1 Regulation of Localization of Grin1 1 0.39 0.18 0.05
100 INT263783 Grin1 Positive_regulation of Mapk1 1 0.14 0 0.03
101 INT294206 Ldlr Positive_regulation of Grin1 1 0.26 0 0.03
102 INT231308 Prnp Negative_regulation of Gene_expression of Grin1 1 0.41 0.05 0.03
103 INT180954 PASK Regulation of COL5A2 1 0.00 0.7 0.03
104 INT231312 Prnp Negative_regulation of Grin1 1 0.42 0.05 0.03
105 INT213549 Phox2b Regulation of Transcription of Phox2a 1 0.44 0.17 0
106 INT213552 Gene_expression of Phox2a Positive_regulation of Gene_expression of Phox2b 1 0.45 0.17 0
107 INT263775 Negative_regulation of Binding of Grin1 and Neto1 1 0.37 0 0
108 INT169858 Grin1 Regulation of Gene_expression of Grin2b 1 0.42 0 0
109 INT294219 PLG Positive_regulation of Grin1 1 0.44 0 0
110 INT213548 Neurog2 Regulation of Transcription of Phox2a 1 0.45 0.17 0
111 INT263758 Positive_regulation of Binding of Grin1 and Neto1 1 0.41 0 0
112 INT299445 Lhb Positive_regulation of Gene_expression of Nr4a2 1 0.22 0.13 0
113 INT169856 Grin1 Positive_regulation of Grin2b 1 0.46 0 0
114 INT213560 Phox2a Regulation of Transcription of Phox2b 1 0.44 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of respiratory gaseous exchange. They are ordered first by their pain relevance and then by number of times they were reported in regulation of respiratory gaseous exchange. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
5 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
6 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
7 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
8 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
9 INT11246 Binding of Grin1 65 0.48 14.53 36.93
10 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
11 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
12 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
13 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
14 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
15 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
16 INT16624 Localization of Grin1 38 0.79 8.46 17.15
17 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
18 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
19 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
20 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
21 INT112103 Binding of Grin1 28 0.48 4.21 12.08
22 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
23 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
24 INT135113 Localization of Grin1 18 0.73 3.73 7.69
25 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
26 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
27 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92
28 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
29 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
30 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
31 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
32 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
33 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
34 INT59433 Gene_expression of PASK 24 0.68 25.13 3.21
35 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
36 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
37 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
38 INT114026 Transcription of Grin1 7 0.67 3.13 2.45
39 INT99607 Transcription of NR4A2 2 0.68 1.61 2.41
40 INT114024 Positive_regulation of Transcription of Grin1 1 0.49 1.69 2.37
41 INT59434 Positive_regulation of PASK 4 0.49 16.64 2.01
42 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89
43 INT195599 Binding of PASK 15 0.36 17.35 1.82
44 INT111405 Negative_regulation of Regulation of Grin1 1 0.54 0.09 1.81
45 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71
46 INT81169 Localization of Nr4a2 1 0.68 0 1.71
47 INT135112 Regulation of Phosphorylation of Grin1 2 0.44 0.3 1.58
48 INT50724 Positive_regulation of Positive_regulation of Nr4a2 2 0.49 0.17 1.58
49 INT74592 Regulation of Transcription of Grin1 2 0.60 1.05 1.51
50 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5
51 INT115355 Regulation of Negative_regulation of Grin1 2 0.23 0.23 1.44
52 INT59040 Regulation of Positive_regulation of Grin1 3 0.27 1.61 1.42
53 INT251602 Regulation of Binding of Grin1 2 0.25 0.05 1.34
54 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28
55 INT96330 Regulation of Regulation of Grin1 2 0.14 0.83 1.2
56 INT105326 Regulation of Localization of Grin1 3 0.44 0.76 1.16
57 INT317484 Positive_regulation of Localization of Grin1 1 0.28 0.11 1.07
58 INT135114 Negative_regulation of Localization of Grin1 1 0.41 0.17 1
59 INT195598 Regulation of PASK 1 0.52 7.57 0.95
60 INT148259 Negative_regulation of Gene_expression of NR4A2 2 0.55 0.71 0.91
61 INT148261 Negative_regulation of Transcription of NR4A2 1 0.41 0.31 0.72
62 INT90714 Positive_regulation of Nr4a2 1 0.67 0.97 0.71
63 INT121717 Positive_regulation of Negative_regulation of Grin1 2 0.66 0.13 0.69
64 INT235994 Protein_catabolism of Grin1 2 0.42 0.64 0.63
65 INT238082 Positive_regulation of Localization of Grin1 2 0.37 0.23 0.61
66 INT149974 Positive_regulation of Gene_expression of NR4A2 4 0.41 0.52 0.58
67 INT148260 Negative_regulation of NR4A2 2 0.36 0.68 0.56
68 INT148258 Regulation of Gene_expression of NR4A2 1 0.26 0.39 0.56
69 INT148265 Regulation of Transcription of NR4A2 1 0.58 0.39 0.56
70 INT271631 Negative_regulation of Localization of Grin1 2 0.32 0.58 0.52
71 INT96771 Localization of PASK 3 0.80 11.6 0.51
72 INT273217 Protein_catabolism of Grin1 1 0.55 1.31 0.43
73 INT170354 Positive_regulation of Binding of Grin1 3 0.49 0 0.38
74 INT157679 Positive_regulation of Gene_expression of PASK 1 0.50 0.07 0.36
75 INT273225 Regulation of Protein_catabolism of Grin1 1 0.30 1.16 0.36
76 INT195597 Negative_regulation of Gene_expression of PASK 1 0.42 1.47 0.35
77 INT90716 Regulation of Gene_expression of Nr4a2 2 0.43 0.41 0.32
78 INT99609 Localization of NR4A2 2 0.73 0.6 0.3
79 INT53816 Negative_regulation of Binding of Grin1 2 0.39 0 0.3
80 INT99611 Negative_regulation of Localization of NR4A2 1 0.42 0.41 0.3
81 INT246013 Transcription of Nr4a2 4 0.46 1.29 0.27
82 INT180976 Negative_regulation of PASK 2 0.37 1.78 0.27
83 INT148898 Negative_regulation of Gene_expression of Nr4a2 3 0.54 1.13 0.26
84 INT276798 Positive_regulation of NR4A2 2 0.16 0.08 0.25
85 INT213524 Transcription of Phox2a 2 0.64 0.29 0.21
86 INT238075 Regulation of Protein_catabolism of Grin1 1 0.13 0 0.16
87 INT238070 Positive_regulation of Protein_catabolism of Grin1 1 0.24 0 0.16
88 INT273228 Positive_regulation of Protein_catabolism of Grin1 1 0.28 0.31 0.14
89 INT159223 Binding of NR4A2 2 0.47 0.38 0.12
90 INT197289 Transcription of Nr4a2 1 0.06 0.06 0.12
91 INT281212 Negative_regulation of Negative_regulation of Grin1 1 0.08 0.06 0.12
92 INT213513 Gene_expression of Phox2a 1 0.72 0.51 0.09
93 INT84940 Binding of Nr4a2 1 0.35 0.09 0.08
94 INT231288 Positive_regulation of Regulation of Grin1 1 0.42 0.24 0.08
95 INT213536 Negative_regulation of Gene_expression of Phox2a 1 0.39 0.1 0.05
96 INT246012 Negative_regulation of Gene_expression of Nr4a2 1 0.29 0.06 0.05
97 INT246014 Negative_regulation of Nr4a2 1 0.29 0 0.05
98 INT213521 Positive_regulation of Gene_expression of Phox2a 1 0.64 0.24 0.04
99 INT246015 Localization of Nr4a2 1 0.50 0 0.03
100 INT213518 Regulation of Gene_expression of Phox2a 1 0.57 0.35 0.03
101 INT183673 Positive_regulation of Localization of PASK 2 0.43 2.4 0
102 INT206868 Regulation of NR4A2 1 0.02 0.28 0
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