GO:0043616

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Name keratinocyte proliferation
Categary Process
Go Slim No
Go Link GO:0043616
Unique Molecular Interactions 286
Total Molecular Interactions 438
Total Single Events 1270
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for keratinocyte proliferation. They are ordered first by their pain relevance and then by number of times they were reported for keratinocyte proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
2 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
3 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
4 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
5 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
6 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
7 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
8 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
9 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
10 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15
11 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
12 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05
13 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
14 INT318490 IRF6 Positive_regulation of LTB4R 1 0.01 4.39 1.03
15 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
16 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
17 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
18 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
19 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
20 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
21 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
22 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
23 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
24 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93
25 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
26 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9
27 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87
28 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
29 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
30 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
31 INT286346 IRF6 Positive_regulation of IL8 3 0.03 0.88 0.8
32 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
33 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75
34 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
35 INT104835 IRF6 Positive_regulation of IL10 4 0.32 0.91 0.69
36 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
37 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
38 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
39 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67
40 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
41 INT318476 IRF6 Positive_regulation of Localization of RETNLB 1 0.00 1.42 0.65
42 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
43 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
44 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
45 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
46 INT115592 IRF6 Positive_regulation of Gene_expression of FAS 1 0.34 0.34 0.62
47 INT85489 IRF6 Negative_regulation of PLOD1 1 0.01 0.16 0.61
48 INT85488 Negative_regulation of IRF6 Negative_regulation of PLOD1 1 0.01 0.16 0.61
49 INT318481 IRF6 Positive_regulation of Gene_expression of FPR2 1 0.14 5.09 0.59
50 INT318487 Negative_regulation of IRF6 Positive_regulation of FPR2 1 0.09 1.39 0.59
51 INT263454 Negative_regulation of IRF6 Positive_regulation of TNF 1 0.12 0.49 0.59
52 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
53 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
54 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
55 INT286349 IRF6 Positive_regulation of Localization of IL10 1 0.03 1.22 0.55
56 INT318478 Negative_regulation of IRF6 Positive_regulation of LTB4R 1 0.01 2.38 0.53
57 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51
58 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
59 INT97800 Gm5564 Regulation of IRF6 1 0.00 0.07 0.5
60 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5
61 INT217037 Binding of IRF6 and Il12a 1 0.01 0.08 0.5
62 INT169400 Negative_regulation of IRF6 Positive_regulation of Gene_expression of Il1b 1 0.50 0.62 0.5
63 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
64 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
65 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48
66 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48
67 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48
68 INT217040 Negative_regulation of IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
69 INT217039 IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
70 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
71 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45
72 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44
73 INT188564 IRF6 Positive_regulation of Gene_expression of PRF1 1 0.01 0.44 0.44
74 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43
75 INT243682 IRF6 Positive_regulation of NEU2 1 0.01 0.18 0.43
76 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43
77 INT188562 IRF6 Regulation of Gene_expression of PRF1 1 0.01 0.7 0.43
78 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42
79 INT84518 IRF6 Positive_regulation of Gene_expression of TF 1 0.14 0.09 0.41
80 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4
81 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
82 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
83 INT318489 Positive_regulation of IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38
84 INT318482 IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38
85 INT144044 IRF6 Positive_regulation of PTGES 1 0.10 0.43 0.37
86 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
87 INT286351 IL8 Positive_regulation of Gene_expression of IRF6 1 0.03 0.71 0.36
88 INT286350 IL6 Positive_regulation of Gene_expression of IRF6 1 0.04 0.71 0.36
89 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35
90 INT250781 IRF6 Positive_regulation of AMIGO2 1 0.02 1.25 0.35
91 INT318484 IRF6 Positive_regulation of Positive_regulation of LTB4R 1 0.01 1.38 0.35
92 INT144048 IRF6 Positive_regulation of Gene_expression of PTGES 1 0.12 0.46 0.35
93 INT318486 IRF6 Positive_regulation of Negative_regulation of FPR2 1 0.10 1.39 0.35
94 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34
95 INT133021 IRF6 Positive_regulation of Gene_expression of IL8 1 0.11 0.51 0.32
96 INT76088 IFNA1 Positive_regulation of IRF6 1 0.19 0.18 0.31
97 INT76086 IRF6 Positive_regulation of ISYNA1 1 0.07 0.18 0.31
98 INT105437 IRF6 Positive_regulation of Localization of PTGER1 1 0.01 0.61 0.31
99 INT187523 IRF6 Positive_regulation of Gene_expression of Cpox 1 0.00 1.38 0.31
100 INT105438 IRF6 Positive_regulation of PTGER1 1 0.01 0.61 0.3
101 INT318480 IRF6 Positive_regulation of Gene_expression of LTB4R 1 0.01 1.63 0.29
102 INT237679 IRF6 Positive_regulation of MAPK8 1 0.00 0.56 0.28
103 INT294709 IRF6 Positive_regulation of Gene_expression of CCL2 1 0.08 0.14 0.28
104 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28
105 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
106 INT295472 IRF6 Positive_regulation of Gene_expression of TNF 2 0.16 0.95 0.27
107 INT318477 Regulation of IRF6 Positive_regulation of LTB4R 1 0.00 1 0.27
108 INT155530 IRF6 Regulation of Gene_expression of IL8 1 0.06 0.79 0.26
109 INT155529 IRF6 Regulation of Transcription of IL6 1 0.08 0.79 0.26
110 INT267631 IRF6 Positive_regulation of Gene_expression of Il1 1 0.00 0.96 0.25
111 INT179233 IRF6 Negative_regulation of Binding of GSR 1 0.03 0.83 0.25
112 INT355567 IRF6 Positive_regulation of MIF 1 0.01 0.29 0.25
113 INT188561 IRF6 Positive_regulation of Transcription of CD14 1 0.03 0.25 0.25
114 INT212568 Fst Regulation of Gene_expression of Il2 1 0.30 0.07 0.24
115 INT14065 IRF6 Positive_regulation of PCA 1 0.24 0.51 0.24
116 INT14064 Negative_regulation of IRF6 Positive_regulation of PCA 1 0.22 0.52 0.24
117 INT318485 Positive_regulation of IRF6 Positive_regulation of LTB4R 1 0.00 1.03 0.23
118 INT84522 IRF6 Positive_regulation of Gene_expression of F3 1 0.08 0.1 0.21
119 INT103869 Binding of IRF6 and Positive_regulation of Hmox1 1 0.10 0.27 0.21
120 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2
121 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
122 INT188568 Negative_regulation of IRF6 Positive_regulation of CD28 1 0.05 0.19 0.19
123 INT335299 IRF6 Positive_regulation of TIMP1 1 0.03 0.21 0.19
124 INT188570 Negative_regulation of IRF6 Positive_regulation of CD4 1 0.04 0.19 0.19
125 INT335298 IRF6 Positive_regulation of MMP9 1 0.01 0.21 0.19
126 INT335311 Binding of IRF6 and SLC15A4 1 0.00 0.23 0.19
127 INT323593 IRF6 Positive_regulation of PROCR 1 0.00 0.46 0.19
128 INT188573 IRF6 Positive_regulation of CD4 1 0.05 0.19 0.19
129 INT323592 IRF6 Positive_regulation of Positive_regulation of PROCR 1 0.00 0.46 0.19
130 INT188571 IRF6 Positive_regulation of CD28 1 0.06 0.19 0.19
131 INT335306 IRF6 Positive_regulation of MMP3 1 0.03 0.21 0.18
132 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18
133 INT335304 IRF6 Positive_regulation of Gene_expression of MMP1 1 0.01 0.21 0.18
134 INT335302 IRF6 Positive_regulation of MMP1 1 0.01 0.21 0.18
135 INT355569 IRF6 Positive_regulation of Gene_expression of NOS2 1 0.00 0.27 0.17
136 INT73506 Binding of IFNG and IRF6 1 0.02 0.42 0.17
137 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17
138 INT104827 IRF6 Positive_regulation of IL12A 2 0.07 0.13 0.16
139 INT208217 IRF6 Positive_regulation of Gene_expression of ISYNA1 1 0.00 0.54 0.16
140 INT104829 Negative_regulation of IRF6 Positive_regulation of IL10 1 0.30 0 0.16
141 INT334590 IRF6 Positive_regulation of Localization of Ptger2 1 0.00 0 0.15
142 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14
143 INT343836 Binding of IRF6 and LBP 1 0.02 0.8 0.14
144 INT316130 IRF6 Positive_regulation of Gene_expression of HLA-DRA 1 0.02 0.27 0.13
145 INT343917 Binding of IRF6 and Hmgb1 1 0.05 0.98 0.13
146 INT322014 Binding of IRF6 and Positive_regulation of Localization of IL1B 1 0.01 0 0.13
147 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13
148 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
149 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12
150 INT105436 IRF6 Positive_regulation of CPOX 1 0.08 0.74 0.11
151 INT231767 Positive_regulation of CD14 Positive_regulation of Binding of IRF6 1 0.04 1.6 0.11
152 INT231770 CD14 Positive_regulation of Binding of IRF6 1 0.04 1.59 0.11
153 INT79444 IL4 Negative_regulation of Positive_regulation of IRF6 2 0.09 0.09 0.1
154 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
155 INT343843 Binding of FN1 and IRF6 1 0.01 0.9 0.1
156 INT294773 IRF6 Positive_regulation of TLR9 1 0.06 0.17 0.1
157 INT294779 IRF6 Positive_regulation of TLR2 1 0.06 0.17 0.1
158 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
159 INT231773 IRF6 Negative_regulation of Gene_expression of HMOX1 1 0.06 1.27 0.09
160 INT285423 LBP Positive_regulation of Gene_expression of IRF6 1 0.07 0.19 0.09
161 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
162 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
163 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08
164 INT180983 IRF6 Regulation of Localization of IL8 1 0.06 0.38 0.08
165 INT343865 IRF6 Positive_regulation of TIRAP 1 0.03 0.28 0.08
166 INT208218 NFKB1 Regulation of IRF6 1 0.01 0.07 0.07
167 INT306255 IRF6 Positive_regulation of TFAM 1 0.01 0 0.07
168 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
169 INT208219 RELA Regulation of IRF6 1 0.00 0.07 0.07
170 INT222431 Tlr4 Positive_regulation of Gene_expression of Fst 1 0.01 0.29 0.06
171 INT318028 Binding of IRF6 and Tlr4 1 0.00 0.61 0.06
172 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05
173 INT222520 Mzb1 Positive_regulation of Gene_expression of Fst 1 0.04 0 0.05
174 INT82578 IRF6 Positive_regulation of Gene_expression of PDE4B 1 0.21 0.09 0.05
175 INT222476 Gnrh1 Negative_regulation of Gene_expression of Fst 1 0.04 0 0.05
176 INT231758 IRF6 Regulation of Gene_expression of HMOX1 1 0.08 0.23 0.05
177 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05
178 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05
179 INT250780 IRF6 Positive_regulation of ASAP1 1 0.06 0.34 0.04
180 INT295475 IRF6 Positive_regulation of Gene_expression of FBRS 1 0.12 0.17 0.04
181 INT335289 IRF6 Positive_regulation of Gene_expression of TIMP1 1 0.03 0.16 0.04
182 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03
183 INT133631 IRF6 Negative_regulation of Transcription of PDYN 1 0.17 0 0.03
184 INT340558 Gene_expression of Fst Positive_regulation of Akt1 1 0.09 0.41 0.03
185 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
186 INT283252 IRF6 Regulation of MIR155 1 0.01 1.04 0.03
187 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
188 INT318479 Positive_regulation of IRF6 Positive_regulation of FPR2 1 0.10 0.94 0.03
189 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
190 INT262150 Binding of Rare1 and Sfn 1 0.01 0.33 0.03
191 INT283255 IRF6 Regulation of MIR15B 1 0.00 1.04 0.03
192 INT295474 IRF6 Positive_regulation of MAP2K1 1 0.18 0.41 0.03
193 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0
194 INT319686 Positive_regulation of Sfn Positive_regulation of Nfe2l2 1 0.18 0 0
195 INT348532 TP63 Positive_regulation of CASP3 1 0.04 0.55 0
196 INT103286 Negative_regulation of IRF6 Positive_regulation of NFKB1 1 0.18 0 0
197 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0
198 INT103287 IRF6 Positive_regulation of NFKB1 1 0.19 0 0
199 INT27743 IRF6 Positive_regulation of TBXA2R 1 0.01 1.03 0
200 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for keratinocyte proliferation. They are ordered first by their pain relevance and then by number of times they were reported in keratinocyte proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81
2 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51
3 INT97798 Localization of IRF6 86 0.73 33.27 20.94
4 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13
5 INT99586 Binding of IRF6 60 0.36 27.87 13.2
6 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83
7 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
8 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24
9 INT60931 Negative_regulation of Fst 15 0.57 5.44 7.21
10 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
11 INT76096 Positive_regulation of Gene_expression of IRF6 37 0.49 14.24 6.39
12 INT86060 Positive_regulation of Fst 13 0.64 3.04 6.33
13 INT150417 Negative_regulation of Gene_expression of IRF6 20 0.41 11.48 6.28
14 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05
15 INT138779 Positive_regulation of Localization of IRF6 25 0.45 11.51 4.51
16 INT97799 Regulation of IRF6 23 0.26 6.54 3.75
17 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
18 INT12844 Binding of TP63 15 0.47 10.57 3.38
19 INT76098 Positive_regulation of Positive_regulation of IRF6 16 0.27 6.05 3.35
20 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
21 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
22 INT33237 Regulation of Fst 10 0.39 1.3 3
23 INT181008 Negative_regulation of Localization of IRF6 13 0.14 2.32 2.96
24 INT112758 Binding of Ppard 7 0.37 3.6 2.87
25 INT237700 Regulation of Negative_regulation of IRF6 2 0.11 1.08 2.58
26 INT237655 Binding of Sfn 1 0.42 3.62 2.55
27 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
28 INT237653 Gene_expression of Sfn 6 0.59 5.54 2.26
29 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
30 INT163580 Positive_regulation of Fst 4 0.19 2.85 2.17
31 INT138316 Regulation of Fst 5 0.44 1.15 1.99
32 INT280933 Binding of Fst 4 0.12 3.53 1.63
33 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
34 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
35 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
36 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
37 INT188397 Regulation of Positive_regulation of IRF6 4 0.12 1.34 1.47
38 INT84888 Binding of PPARD 5 0.48 2.82 1.45
39 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
40 INT95367 Negative_regulation of Positive_regulation of IRF6 7 0.21 3.5 1.34
41 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
42 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
43 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
44 INT185929 Regulation of Gene_expression of IRF6 9 0.20 1.66 0.99
45 INT112759 Negative_regulation of Binding of Ppard 2 0.39 2.08 0.99
46 INT280942 Localization of Fst 2 0.22 2.13 0.91
47 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
48 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
49 INT89340 Positive_regulation of EREG 5 0.69 4.98 0.77
50 INT44293 Regulation of TP63 6 0.24 2.88 0.76
51 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
52 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
53 INT156967 Localization of Fst 2 0.66 0.1 0.66
54 INT156968 Negative_regulation of Localization of Fst 1 0.37 0.1 0.64
55 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
56 INT185397 Positive_regulation of Binding of IRF6 3 0.12 0.56 0.57
57 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
58 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
59 INT349703 Positive_regulation of Transcription of Fst 1 0.46 0.14 0.53
60 INT349725 Transcription of Fst 1 0.63 0.13 0.53
61 INT97796 Regulation of Localization of IRF6 2 0.20 0.32 0.5
62 INT237651 Negative_regulation of Sfn 3 0.51 1.7 0.49
63 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49
64 INT216998 Regulation of Binding of IRF6 2 0.05 0.06 0.48
65 INT278121 Negative_regulation of Negative_regulation of TP63 1 0.03 0 0.48
66 INT237703 Phosphorylation of IRF6 2 0.05 0.91 0.47
67 INT101515 Negative_regulation of Positive_regulation of PPARD 2 0.35 0.68 0.47
68 INT84893 Negative_regulation of Binding of PPARD 1 0.43 0.5 0.46
69 INT188395 Regulation of Regulation of IRF6 1 0.06 0.89 0.46
70 INT289471 Negative_regulation of Negative_regulation of IRF6 1 0.10 0.31 0.45
71 INT132946 Negative_regulation of Positive_regulation of Ppard 1 0.42 0.09 0.44
72 INT181007 Protein_catabolism of IRF6 3 0.61 1.17 0.39
73 INT89341 Gene_expression of EREG 3 0.78 2.38 0.38
74 INT317694 Negative_regulation of Localization of Fst 1 0.12 0.79 0.36
75 INT89342 Transcription of EREG 1 0.69 1.22 0.35
76 INT288541 Negative_regulation of Gene_expression of Fst 2 0.23 1.18 0.34
77 INT349714 Binding of Fst 1 0.34 0.19 0.32
78 INT89339 Regulation of EREG 2 0.27 1.86 0.31
79 INT144419 Regulation of Ppard 1 0.24 0.91 0.3
80 INT61115 Localization of Ppard 2 0.66 1.99 0.28
81 INT159198 Positive_regulation of Binding of Ppard 1 0.34 0.68 0.28
82 INT237652 Positive_regulation of Sfn 3 0.49 1.17 0.27
83 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
84 INT185399 Negative_regulation of Binding of IRF6 1 0.07 1.12 0.25
85 INT162564 Gene_expression of KRT2 5 0.59 1.75 0.24
86 INT263475 Negative_regulation of Protein_catabolism of IRF6 1 0.36 0.48 0.21
87 INT318506 Positive_regulation of Negative_regulation of IRF6 1 0.11 0.75 0.19
88 INT139201 Localization of TP63 4 0.32 2.56 0.15
89 INT145147 Negative_regulation of Gene_expression of TP63 4 0.42 2.91 0.15
90 INT222654 Regulation of Gene_expression of Fst 1 0.09 0 0.15
91 INT256864 Gene_expression of Tp63 1 0.14 0.47 0.14
92 INT342320 Positive_regulation of Irf6 1 0.44 1.08 0.13
93 INT186516 Regulation of PPARD 1 0.15 1.12 0.11
94 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
95 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
96 INT270450 Transcription of Ptch1 1 0.49 0.55 0.09
97 INT165148 Regulation of Binding of Ptch1 1 0.22 0.08 0.08
98 INT270452 Regulation of Gene_expression of Ptch1 1 0.25 0.25 0.08
99 INT256854 Regulation of Tp63 1 0.06 0.06 0.08
100 INT136890 Protein_catabolism of TP63 2 0.56 1.17 0.07
101 INT165154 Negative_regulation of Positive_regulation of Ptch1 1 0.34 0.09 0.07
102 INT183056 Positive_regulation of Transcription of PTCH1 1 0.28 0.46 0.07
103 INT255719 Phosphorylation of Ptch1 1 0.32 3.7 0.06
104 INT223571 Localization of PPARD 1 0.73 0.39 0.06
105 INT222593 Negative_regulation of Gene_expression of Fst 1 0.07 0 0.05
106 INT255726 Localization of Ptch1 1 0.33 1.74 0.05
107 INT183070 Transcription of PTCH1 2 0.68 0.95 0.04
108 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
109 INT340535 Positive_regulation of Gene_expression of Fst 1 0.26 0.4 0.03
110 INT307325 Negative_regulation of Gene_expression of EREG 1 0.01 0.31 0.03
111 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
112 INT340540 Regulation of Gene_expression of Fst 1 0.17 0.42 0.03
113 INT183064 Regulation of Gene_expression of PTCH1 1 0.34 0.22 0.03
114 INT222613 Positive_regulation of Gene_expression of Fst 4 0.42 0.25 0
115 INT209451 Regulation of Gene_expression of TP63 3 0.16 4.32 0
116 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0
117 INT255723 Positive_regulation of Gene_expression of Ptch1 2 0.39 1.3 0
118 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0
119 INT233002 Binding of KRT2 1 0.29 0 0
120 INT319641 Negative_regulation of Positive_regulation of Sfn 1 0.18 0 0
121 INT260088 Negative_regulation of Transcription of PTCH1 1 0.43 0.4 0
122 INT347150 Protein_catabolism of Sfn 1 0.96 0 0
123 INT260089 Localization of PTCH1 1 0.70 0.37 0
124 INT327160 Negative_regulation of Gene_expression of KRT2 1 0.01 0.15 0
125 INT270455 Negative_regulation of Gene_expression of Ptch1 1 0.39 0.66 0
126 INT237708 Negative_regulation of Regulation of IRF6 1 0.03 0 0
127 INT280555 Regulation of Binding of TP63 1 0.12 0.93 0
128 INT199005 Localization of KRT2 1 0.05 1.5 0
129 INT333599 Positive_regulation of Phosphorylation of IRF6 1 0.03 0 0
130 INT201567 Positive_regulation of Protein_catabolism of TP63 1 0.23 1.17 0
131 INT342325 Regulation of Irf6 1 0.25 0 0
132 INT183052 Positive_regulation of Gene_expression of PTCH1 1 0.38 0.26 0
133 INT260080 Negative_regulation of Gene_expression of PTCH1 1 0.58 2.09 0
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