GO:0043619

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Name regulation of transcription from RNA polymerase II promoter in response to oxidative stress
Categary Process
Go Slim No
Go Link GO:0043619
Unique Molecular Interactions 211
Total Molecular Interactions 271
Total Single Events 2782
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of transcription from RNA polymerase II promoter in response to oxidative stress. They are ordered first by their pain relevance and then by number of times they were reported for regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
2 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
3 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
4 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
5 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
6 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
7 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
8 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
9 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
10 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
11 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
12 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
13 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53
14 INT350076 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 1.29 0.5
15 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
16 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
17 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
18 INT148466 Ccl4 Positive_regulation of Hmox1 1 0.28 0.06 0.47
19 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
20 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45
21 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45
22 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
23 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
24 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
25 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4
26 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39
27 INT147472 co Positive_regulation of Gene_expression of Hmox1 1 0.01 0.57 0.36
28 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
29 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
30 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
31 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
32 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25
33 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25
34 INT350099 Gene_expression of Hmox1 Positive_regulation of Gene_expression of MRXS5 1 0.01 0.51 0.24
35 INT328228 Binding of Cpox and Hmox1 1 0.03 0.83 0.23
36 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
37 INT350065 Gene_expression of Hmox1 Negative_regulation of Gene_expression of Tlr4 1 0.18 0.35 0.22
38 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
39 INT103867 SFTPA1 Positive_regulation of Hmox1 1 0.00 0.35 0.22
40 INT64340 Zc3h15 Negative_regulation of Hmox1 1 0.12 0.47 0.22
41 INT350078 Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 0.35 0.22
42 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
43 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
44 INT103869 Binding of IRF6 and Positive_regulation of Hmox1 1 0.10 0.27 0.21
45 INT349647 Eif2ak1 Positive_regulation of Positive_regulation of Hmox1 1 0.00 1.07 0.2
46 INT350096 Hmox1 Negative_regulation of Gene_expression of MRXS5 1 0.01 0.32 0.2
47 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2
48 INT349646 Eif2ak1 Regulation of Gene_expression of Hmox1 1 0.00 0.78 0.2
49 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19
50 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
51 INT199192 Gnat3 Positive_regulation of Hmox1 1 0.27 0.23 0.19
52 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
53 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
54 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
55 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
56 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
57 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16
58 INT350072 Ptger2 Positive_regulation of Hmox1 1 0.02 0.2 0.15
59 INT231757 TLR4 Positive_regulation of Negative_regulation of HMOX1 1 0.26 1.37 0.15
60 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
61 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
62 INT216882 Tlr4 Positive_regulation of Hmox1 1 0.17 0.19 0.15
63 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
64 INT350081 Pik3r1 Positive_regulation of Hmox1 1 0.07 0.2 0.15
65 INT350069 Prkaca Positive_regulation of Hmox1 1 0.05 0.2 0.15
66 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
67 INT199195 Gnat3 Regulation of Transcription of Hmox1 1 0.24 0.12 0.14
68 INT295267 Binding of Hmox1 and Gtf3a 1 0.01 0.49 0.13
69 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
70 INT295261 Binding of Hmox1 and Nfe2l2 1 0.17 0.49 0.13
71 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
72 INT295264 Positive_regulation of Binding of Hmox1 and Nfe2l2 1 0.25 0.5 0.13
73 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
74 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
75 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
76 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12
77 INT231761 TNF Negative_regulation of HMOX1 1 0.19 1.2 0.12
78 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12
79 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
80 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
81 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11
82 INT231764 TLR4 Negative_regulation of HMOX1 1 0.27 1.54 0.11
83 INT231768 Binding of HMOX1 and TLR4 1 0.23 0.95 0.11
84 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1
85 INT231772 TNF Positive_regulation of Gene_expression of HMOX1 1 0.21 0.96 0.1
86 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
87 INT102245 TNF Positive_regulation of Binding of HIF1A 1 0.18 1.09 0.1
88 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
89 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1
90 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
91 INT231773 IRF6 Negative_regulation of Gene_expression of HMOX1 1 0.06 1.27 0.09
92 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09
93 INT173062 Binding of HIF1A and VHLL 1 0.04 1.26 0.09
94 INT173057 Positive_regulation of HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.24 1.49 0.08
95 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
96 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
97 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 0.00 1 0.08
98 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
99 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
100 INT178103 Binding of DBP and HIF1A 1 0.00 0.99 0.07
101 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
102 INT247578 Hif1a Regulation of VEGFA 1 0.02 1.59 0.07
103 INT241400 Epas1 Positive_regulation of Gene_expression of VEGFA 1 0.03 1.09 0.07
104 INT268675 Binding of NCOR2 and SIN3A 1 0.27 2.54 0.07
105 INT244290 Il6 Positive_regulation of Hmox1 1 0.38 0.09 0.07
106 INT244291 Nos2 Positive_regulation of Positive_regulation of Hmox1 1 0.34 0.07 0.07
107 INT231760 TNF Positive_regulation of Protein_catabolism of HMOX1 1 0.31 0.41 0.06
108 INT200212 Binding of EPAS1 and VHL 3 0.06 4.1 0.05
109 INT349645 Eif2ak1 Positive_regulation of Hmox1 1 0.00 0.18 0.05
110 INT308328 Hif1a Regulation of Positive_regulation of Trib3 1 0.02 0.89 0.05
111 INT231758 IRF6 Regulation of Gene_expression of HMOX1 1 0.08 0.23 0.05
112 INT304322 Hif1a Positive_regulation of Positive_regulation of VEGFA 1 0.11 0.39 0.05
113 INT224310 EPAS1 Positive_regulation of CXCL12 1 0.02 0.63 0.05
114 INT231766 TLR4 Negative_regulation of Gene_expression of HMOX1 1 0.28 0.71 0.05
115 INT231771 Binding of HMOX1 and TNF 2 0.14 1.41 0.04
116 INT231759 IL10 Positive_regulation of Gene_expression of HMOX1 1 0.06 0.7 0.04
117 INT249921 Binding of Hif1a and Asph 1 0.05 0.41 0.04
118 INT102247 Binding of EPO and HIF1A 1 0.41 0.65 0.04
119 INT173060 Negative_regulation of VHLL Positive_regulation of Positive_regulation of HIF1A 1 0.04 0.66 0.04
120 INT349648 Eif2ak1 Positive_regulation of Gene_expression of Hmox1 1 0.00 0.17 0.04
121 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04
122 INT231775 TLR4 Regulation of Gene_expression of HMOX1 1 0.29 0.68 0.04
123 INT178503 Binding of Cd36 and ecs 1 0.01 0.34 0.04
124 INT231774 Gene_expression of TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
125 INT231762 TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
126 INT262177 Nr1i2 Positive_regulation of Cd36 1 0.16 0.18 0.03
127 INT297159 Gsta3 Negative_regulation of Hif1a 1 0.00 0.54 0.03
128 INT322471 Hif1a Positive_regulation of VEGFA 1 0.05 0.26 0.03
129 INT335492 CREM Positive_regulation of Transcription of HMOX1 1 0.00 0.9 0.03
130 INT350071 Hmox1 Regulation of Tlr4 1 0.22 0.33 0.03
131 INT219423 Binding of AHR and ARNT 4 0.24 0.46 0
132 INT247576 Binding of Hif1a and Vbp1 1 0.01 0.6 0
133 INT189554 Binding of HIF1A and Positive_regulation of EGLN1 1 0.04 0.86 0
134 INT135174 Myst2 Positive_regulation of Binding of Hif1a 1 0.41 0 0
135 INT351099 EPAS1 Regulation of Gene_expression of CRTC1 1 0.00 0.8 0
136 INT143438 HIF1A Regulation of Gene_expression of VEGFA 1 0.69 0.13 0
137 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0
138 INT219418 ARNT Positive_regulation of Localization of AHR 1 0.25 0 0
139 INT229818 Fos Positive_regulation of Hmox1 1 0.43 0.37 0
140 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
141 INT247574 Ube2e3 Positive_regulation of Hif1a 1 0.04 0.62 0
142 INT339260 EPAS1 Positive_regulation of VEGFA 1 0.19 3.67 0
143 INT193014 VHL Regulation of EPAS1 1 0.20 0.92 0
144 INT241307 Positive_regulation of HIF1A Positive_regulation of Positive_regulation of EPO 1 0.12 0.64 0
145 INT247575 Binding of Epo and Hif1a 1 0.09 1.24 0
146 INT290478 Mitf Positive_regulation of HIF1A 1 0.57 0.61 0
147 INT135175 Myst2 Positive_regulation of Hif1a 1 0.41 0 0
148 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
149 INT259670 CSE Positive_regulation of Hmox1 1 0.06 0.97 0
150 INT278242 MSC Regulation of Gene_expression of Cd36 1 0.08 1.17 0
151 INT189552 EGLN1 Positive_regulation of HIF1A 1 0.05 0.98 0
152 INT260496 Hif1a Regulation of Gene_expression of VEGFA 1 0.12 0.93 0
153 INT193013 VHL Regulation of Regulation of EPAS1 1 0.14 1.74 0
154 INT330735 GSTK1 Regulation of HMOX1 1 0.08 0.25 0
155 INT260398 Dclk2 Regulation of Gene_expression of Hmox1 1 0.01 1.02 0
156 INT290373 Binding of Cd36 and Scarb1 1 0.11 0 0
157 INT249924 Cpox Positive_regulation of Hif1a 1 0.01 0.68 0
158 INT301469 Negative_regulation of Binding of Sin3a and Smyd2 1 0.28 0.31 0
159 INT337352 Binding of ARNT and HIF1A 1 0.14 0.61 0
160 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0
161 INT262710 Binding of Crem and Hif1a 1 0.00 1.85 0
162 INT299462 Binding of Mxd1 and Sin3a 1 0.08 0.62 0
163 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0
164 INT219505 ARNT Positive_regulation of Positive_regulation of Ppib 1 0.50 0 0
165 INT351098 MTOR Regulation of Binding of EPAS1 1 0.08 0.95 0
166 INT301475 Binding of Sin3a and Smyd2 1 0.32 0.31 0
167 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
168 INT232003 Cd36 Positive_regulation of Transcription of Fasl 1 0.10 0.66 0
169 INT299463 Binding of Sin3a and SIDT1 1 0.39 0.31 0
170 INT143439 Positive_regulation of HIF1A Regulation of Gene_expression of VEGFA 1 0.30 0.13 0
171 INT339262 EPAS1 Positive_regulation of Gene_expression of VEGFA 1 0.14 0.23 0
172 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0
173 INT290479 Binding of HIF1A and Mitf 1 0.30 1.29 0
174 INT260393 Hmox1 Regulation of Positive_regulation of Bcl2 1 0.22 0.86 0
175 INT119044 HIF1A Regulation of TCEAL1 1 0.02 1.06 0
176 INT313884 XRCC1 Positive_regulation of Localization of HIF1A 1 0.00 0.65 0
177 INT301906 Binding of HMOX1 and HSD11B1 1 0.05 2.41 0
178 INT119047 HIF1A Regulation of Regulation of TCEAL1 1 0.08 1.06 0
179 INT350068 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptgs2 1 0.03 0.16 0
180 INT345487 HIF1A Positive_regulation of PMAIP1 1 0.27 1.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of transcription from RNA polymerase II promoter in response to oxidative stress. They are ordered first by their pain relevance and then by number of times they were reported in regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
2 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
3 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
4 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
5 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
6 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
7 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
8 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
9 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
10 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
11 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
12 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
13 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
14 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
15 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
16 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
17 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
18 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2
19 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
20 INT80224 Regulation of Hmox1 19 0.32 10.53 3.52
21 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
22 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3
23 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
24 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
25 INT127904 Negative_regulation of Gene_expression of Hmox1 11 0.42 9.54 2.8
26 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
27 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46
28 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
29 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
30 INT96881 Gene_expression of ARNT 8 0.50 3.27 1.98
31 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94
32 INT99742 Negative_regulation of Gene_expression of Hmox1 12 0.58 9.94 1.77
33 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7
34 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
35 INT80227 Regulation of Gene_expression of Hmox1 12 0.44 11.04 1.61
36 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
37 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55
38 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
39 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
40 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
41 INT103305 Positive_regulation of Positive_regulation of Hmox1 8 0.49 4.81 1.49
42 INT100420 Regulation of HMOX1 10 0.35 6.68 1.48
43 INT165680 Transcription of HMOX1 7 0.71 11.2 1.41
44 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
45 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3
46 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28
47 INT91320 Localization of Hmox1 8 0.81 4.06 1.28
48 INT115831 Transcription of Hmox1 16 0.66 5.31 1.14
49 INT199187 Localization of Hmox1 2 0.78 3.36 1.11
50 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
51 INT116529 Binding of HMOX1 10 0.47 15.38 1.04
52 INT105445 Localization of HMOX1 5 0.71 3.11 0.98
53 INT201454 Positive_regulation of Positive_regulation of Hmox1 6 0.35 5.2 0.94
54 INT148461 Positive_regulation of Transcription of Hmox1 6 0.33 1.83 0.93
55 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
56 INT178485 Binding of Cd36 11 0.22 6.65 0.8
57 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
58 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
59 INT82568 Protein_catabolism of Hmox1 5 0.86 1.03 0.79
60 INT144540 Negative_regulation of Gene_expression of Sin3a 1 0.57 0.85 0.75
61 INT144544 Gene_expression of Sin3a 1 0.75 0.84 0.74
62 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
63 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72
64 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
65 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
66 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
67 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
68 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
69 INT287003 Negative_regulation of Positive_regulation of Hmox1 2 0.34 3.1 0.63
70 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
71 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
72 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
73 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
74 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
75 INT165681 Positive_regulation of Transcription of HMOX1 2 0.69 4.29 0.53
76 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
77 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
78 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
79 INT270030 Negative_regulation of Positive_regulation of Hmox1 3 0.30 2.49 0.47
80 INT144969 Binding of EPAS1 3 0.06 4.12 0.44
81 INT96870 Transcription of ARNT 1 0.44 0.81 0.4
82 INT157157 Negative_regulation of Localization of HMOX1 1 0.37 0.74 0.37
83 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
84 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
85 INT281659 Regulation of Transcription of HMOX1 2 0.27 2.12 0.33
86 INT247563 Negative_regulation of Positive_regulation of Hif1a 1 0.16 9.12 0.32
87 INT216879 Binding of Hmox1 4 0.36 2.82 0.31
88 INT233881 Positive_regulation of Cd36 8 0.48 4.68 0.29
89 INT135772 Regulation of Positive_regulation of HMOX1 3 0.39 1.52 0.29
90 INT173105 Transcription of HIF1A 6 0.67 4.47 0.28
91 INT328227 Positive_regulation of Localization of Hmox1 1 0.45 0.67 0.28
92 INT91231 Binding of Hmox1 4 0.36 0.29 0.27
93 INT232786 Positive_regulation of Localization of Hif1a 2 0.31 2.63 0.27
94 INT201453 Protein_catabolism of Hmox1 3 0.95 4.25 0.23
95 INT96872 Positive_regulation of ARNT 2 0.32 1.82 0.23
96 INT96878 Positive_regulation of Gene_expression of ARNT 1 0.32 0.44 0.23
97 INT96880 Positive_regulation of Transcription of ARNT 1 0.30 0.44 0.23
98 INT350048 Negative_regulation of Regulation of Hmox1 1 0.30 0.37 0.23
99 INT193015 Positive_regulation of Gene_expression of EPAS1 6 0.32 8.77 0.21
100 INT173103 Positive_regulation of Transcription of HIF1A 3 0.49 2.11 0.21
101 INT247564 Positive_regulation of Transcription of Hif1a 1 0.19 2.05 0.2
102 INT96874 Regulation of Transcription of ARNT 1 0.29 0.38 0.18
103 INT280465 Negative_regulation of Sin3a 2 0.41 1.07 0.17
104 INT115829 Regulation of Transcription of Hmox1 1 0.35 1.03 0.17
105 INT200220 Positive_regulation of Positive_regulation of EPAS1 2 0.09 2 0.16
106 INT339266 Regulation of Gene_expression of EPAS1 3 0.11 2.92 0.14
107 INT249919 Regulation of Regulation of Hif1a 2 0.29 1.81 0.14
108 INT249908 Binding of Hif1a 2 0.31 1.48 0.14
109 INT249913 Regulation of Gene_expression of Hif1a 2 0.32 1.82 0.13
110 INT201467 Protein_catabolism of HMOX1 2 0.77 0.83 0.13
111 INT272873 Gene_expression of Epas1 1 0.05 1.57 0.13
112 INT272871 Positive_regulation of Gene_expression of Epas1 1 0.03 1.58 0.13
113 INT105392 Positive_regulation of Binding of HIF1A 5 0.45 3.83 0.1
114 INT153064 Positive_regulation of Regulation of Hif1a 1 0.45 1.52 0.1
115 INT183671 Localization of EPAS1 5 0.16 5.41 0.09
116 INT260478 Negative_regulation of Positive_regulation of Hif1a 2 0.30 1.23 0.09
117 INT260462 Negative_regulation of Binding of Hif1a 1 0.30 1.13 0.09
118 INT224327 Negative_regulation of EPAS1 5 0.09 4.29 0.08
119 INT260451 Positive_regulation of Positive_regulation of Hif1a 1 0.36 1.01 0.08
120 INT199067 Negative_regulation of Gene_expression of Cd36 3 0.28 0.9 0.07
121 INT297157 Negative_regulation of Negative_regulation of Hif1a 1 0.03 0.54 0.07
122 INT247560 Negative_regulation of Negative_regulation of Hif1a 1 0.16 2.06 0.07
123 INT241390 Positive_regulation of Epas1 1 0.03 1.03 0.07
124 INT193016 Regulation of EPAS1 9 0.15 7.38 0.06
125 INT115824 Positive_regulation of Transcription of Hmox1 3 0.45 0.43 0.06
126 INT143444 Positive_regulation of Localization of HIF1A 3 0.45 1.26 0.06
127 INT247553 Regulation of Negative_regulation of Hif1a 1 0.17 1.36 0.06
128 INT297158 Regulation of Localization of Hif1a 1 0.03 0.32 0.06
129 INT247559 Regulation of Positive_regulation of Hif1a 2 0.23 1.64 0.05
130 INT247555 Positive_regulation of Binding of Hif1a 2 0.31 1.15 0.05
131 INT233879 Negative_regulation of Positive_regulation of Cd36 1 0.12 0.81 0.05
132 INT297156 Localization of Hif1a 1 0.06 0.32 0.05
133 INT322464 Regulation of Localization of Hif1a 1 0.28 0.59 0.05
134 INT196696 Negative_regulation of Cd36 5 0.18 5.5 0.04
135 INT206043 Transcription of Cd36 4 0.37 2.59 0.04
136 INT155174 Regulation of Regulation of HIF1A 3 0.24 1.57 0.04
137 INT293311 Positive_regulation of Positive_regulation of HMOX1 3 0.69 1.99 0.04
138 INT299425 Binding of Sin3a 2 0.36 0.92 0.04
139 INT173079 Positive_regulation of Regulation of HIF1A 1 0.26 0.64 0.04
140 INT249918 Regulation of Protein_catabolism of Hif1a 1 0.29 0.4 0.04
141 INT350052 Positive_regulation of Negative_regulation of Hmox1 1 0.35 0.34 0.04
142 INT249916 Protein_catabolism of Hif1a 1 0.64 0.39 0.04
143 INT242952 Regulation of Gene_expression of Cd36 1 0.31 0.71 0.04
144 INT105389 Negative_regulation of Binding of HIF1A 4 0.42 3.2 0.03
145 INT219493 Binding of ARNT 3 0.23 1.4 0
146 INT206050 Positive_regulation of Transcription of Cd36 3 0.32 1.72 0
147 INT236559 Regulation of Cd36 2 0.42 0.65 0
148 INT219456 Localization of ARNT 2 0.48 0.61 0
149 INT112351 Negative_regulation of Epas1 2 0.05 0.3 0
150 INT339265 Negative_regulation of Gene_expression of EPAS1 2 0.15 2.67 0
151 INT189607 Regulation of Binding of HIF1A 2 0.06 1.49 0
152 INT251998 Protein_catabolism of EPAS1 2 0.03 2.68 0
153 INT281337 Regulation of ARNT 1 0.05 0.59 0
154 INT189594 Negative_regulation of Transcription of HIF1A 1 0.05 0.94 0
155 INT249915 Regulation of Positive_regulation of Hif1a 1 0.29 0.85 0
156 INT351121 Positive_regulation of Negative_regulation of EPAS1 1 0.09 0.86 0
157 INT112706 Negative_regulation of Gene_expression of Hif1a 1 0.08 0 0
158 INT337766 Phosphorylation of Hmox1 1 0.79 0.08 0
159 INT322450 Negative_regulation of Binding of Hif1a 1 0.26 0.32 0
160 INT252004 Negative_regulation of Regulation of EPAS1 1 0.02 1.17 0
161 INT256244 Positive_regulation of Regulation of Cd36 1 0.32 0.7 0
162 INT189606 Regulation of Transcription of HIF1A 1 0.06 0.46 0
163 INT281335 Negative_regulation of ARNT 1 0.02 0.31 0
164 INT249917 Regulation of Negative_regulation of Hif1a 1 0.29 0.29 0
165 INT337767 Positive_regulation of Phosphorylation of Hmox1 1 0.49 0.08 0
166 INT203725 Localization of Cd36 1 0.43 0.81 0
167 INT206044 Protein_catabolism of Cd36 1 0.12 0.46 0
168 INT247562 Negative_regulation of Transcription of Hif1a 1 0.16 2.39 0
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