GO:0043624

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Name cellular protein complex disassembly
Categary Process
Go Slim No
Go Link GO:0043624
Unique Molecular Interactions 28
Total Molecular Interactions 38
Total Single Events 169
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular protein complex disassembly. They are ordered first by their pain relevance and then by number of times they were reported for cellular protein complex disassembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
2 INT155958 Binding of Kcnk2 and Akap5 1 0.15 0.64 0.48
3 INT235887 CALM1 Regulation of Akap5 1 0.00 0 0.39
4 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
5 INT235861 Binding of Prkaca and Akap5 1 0.20 0 0.35
6 INT235862 Binding of Ppp3r2 and Akap5 1 0.01 0 0.35
7 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35
8 INT154194 Binding of KCNK2 and Akap5 1 0.08 0.19 0.29
9 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26
10 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25
11 INT134523 Nrg1 Positive_regulation of Gene_expression of Mpz 1 0.49 0.32 0.23
12 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2
13 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14
14 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11
15 INT231273 Binding of Egfr and Nrg1 1 0.12 0 0.09
16 INT341008 Nrg1 Regulation of Binding of Erbb4 1 0.04 0 0.09
17 INT54096 NRG1 Regulation of Protein_catabolism of Fgg 1 0.01 0 0.09
18 INT341009 Nrg1 Positive_regulation of Gene_expression of Fabp7 1 0.10 0.49 0.04
19 INT231276 Erbb4 Positive_regulation of Nrg1 2 0.35 0.06 0.03
20 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03
21 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03
22 INT231275 Erbb4 Positive_regulation of Gene_expression of Nrg1 1 0.35 0 0.03
23 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03
24 INT341005 Binding of Vim and Nrg1 1 0.05 0.14 0
25 INT341013 Binding of Erbb3 and Nrg1 1 0.04 0.14 0
26 INT341023 PIK3CB Positive_regulation of Nrg1 1 0.03 0.06 0
27 INT341010 Nrg1 Positive_regulation of Regulation of Vim 1 0.07 0 0
28 INT341014 Positive_regulation of Binding of Erbb3 and Nrg1 1 0.06 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular protein complex disassembly. They are ordered first by their pain relevance and then by number of times they were reported in cellular protein complex disassembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15771 Gene_expression of Nrg1 34 0.67 3.16 4.11
2 INT168983 Negative_regulation of Nrg1 11 0.43 3.4 2.03
3 INT105784 Binding of Nrg1 7 0.37 1.29 1.52
4 INT158056 Localization of Nrg1 13 0.79 3.11 1.28
5 INT30851 Gene_expression of NRG1 8 0.67 4.64 1.12
6 INT101994 Positive_regulation of Nrg1 10 0.50 1.24 1.05
7 INT19084 Negative_regulation of NRG1 5 0.42 4.9 0.96
8 INT139846 Protein_catabolism of Nrg1 5 0.60 1.78 0.74
9 INT126736 Positive_regulation of Gene_expression of Nrg1 3 0.50 0.42 0.71
10 INT290081 Regulation of NRG1 7 0.26 5.24 0.59
11 INT15770 Negative_regulation of Gene_expression of Nrg1 3 0.43 1.27 0.5
12 INT19083 Positive_regulation of NRG1 3 0.20 0.65 0.48
13 INT290096 Regulation of Gene_expression of NRG1 2 0.06 2.21 0.35
14 INT334851 Positive_regulation of Localization of Nrg1 1 0.30 0.68 0.34
15 INT203557 Transcription of NRG1 2 0.31 0.7 0.24
16 INT54093 Protein_catabolism of NRG1 1 0.26 0 0.16
17 INT231261 Regulation of Nrg1 3 0.31 1.32 0.15
18 INT220571 Positive_regulation of Protein_catabolism of Nrg1 1 0.30 0.08 0.15
19 INT323165 Regulation of Akap5 1 0.10 0.08 0.14
20 INT203559 Positive_regulation of Transcription of NRG1 1 0.22 0 0.11
21 INT54092 Regulation of Protein_catabolism of NRG1 1 0.13 0 0.09
22 INT329735 Negative_regulation of Protein_catabolism of Nrg1 1 0.36 0.49 0.08
23 INT323163 Negative_regulation of Akap5 1 0.16 0.1 0.07
24 INT323162 Transcription of Akap5 1 0.19 0.1 0.07
25 INT54094 Positive_regulation of Protein_catabolism of NRG1 1 0.14 0 0.07
26 INT334840 Positive_regulation of Phosphorylation of Nrg1 1 0.30 0 0.06
27 INT290102 Localization of NRG1 1 0.15 0.76 0.06
28 INT220593 Negative_regulation of Localization of Nrg1 1 0.26 0.07 0.04
29 INT334841 Negative_regulation of Phosphorylation of Nrg1 1 0.26 0 0.03
30 INT340964 Positive_regulation of Negative_regulation of Nrg1 1 0.28 0.12 0.03
31 INT334845 Phosphorylation of Nrg1 1 0.49 0 0.03
32 INT340965 Negative_regulation of Binding of Nrg1 1 0.24 0 0
33 INT220588 Transcription of Nrg1 1 0.41 0.64 0
34 INT171658 Binding of NRG1 1 0.05 0.17 0
35 INT340954 Positive_regulation of Positive_regulation of Nrg1 1 0.28 0 0
36 INT234187 Positive_regulation of Gene_expression of NRG1 1 0.02 0.32 0
37 INT340974 Negative_regulation of Negative_regulation of Nrg1 1 0.24 0 0
38 INT231271 Regulation of Localization of Nrg1 1 0.45 0 0
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