GO:0043966

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Name histone H3 acetylation
Categary Process
Go Slim No
Go Link GO:0043966
Unique Molecular Interactions 92
Total Molecular Interactions 123
Total Single Events 478
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone H3 acetylation. They are ordered first by their pain relevance and then by number of times they were reported for histone H3 acetylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
2 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
3 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
4 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
5 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
6 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
7 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
8 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
9 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
10 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
11 INT300549 Il1 Regulation of Gene_expression of Irf4 1 0.01 0.63 0.33
12 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33
13 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
14 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
15 INT334261 Binding of Irf4 and Irf5 1 0.22 0.42 0.18
16 INT65744 Map3k7 Negative_regulation of Gene_expression of Il2 1 0.10 0.74 0.18
17 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14
18 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
19 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
20 INT149541 Binding of GCA and TADA1 1 0.40 1.4 0.13
21 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13
22 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
23 INT242881 SPI1 Negative_regulation of Regulation of TLR2 1 0.04 1.13 0.11
24 INT243216 Myst2 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.75 0.11
25 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1
26 INT243215 Myst2 Negative_regulation of Gene_expression of Icam1 1 0.01 0.68 0.1
27 INT35691 IGHG3 Positive_regulation of Gene_expression of SUPT7L 1 0.26 0.18 0.09
28 INT88752 Map3k7 Negative_regulation of Ednra 1 0.05 0 0.08
29 INT243213 Myst2 Negative_regulation of Alms1 1 0.01 0.91 0.08
30 INT242880 Binding of SPI1 and TLR4 1 0.03 0.24 0.07
31 INT223531 Binding of Hmga1 and Tcf3 1 0.26 0.57 0.07
32 INT182943 Binding of DR1 and NR1H4 3 0.03 0.14 0.06
33 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 0.04 0.23 0.05
34 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
35 INT175083 TAF6L Regulation of Gene_expression of PENK 1 0.00 0.05 0.04
36 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
37 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03
38 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03
39 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
40 INT182918 Binding of DR1 and RARA 2 0.08 0 0
41 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
42 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
43 INT135174 Myst2 Positive_regulation of Binding of Hif1a 1 0.41 0 0
44 INT242876 Negative_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
45 INT348018 Map3k7 Positive_regulation of Chuk 1 0.19 0.06 0
46 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
47 INT284296 Mir155 Regulation of Spi1 1 0.25 0.36 0
48 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
49 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0
50 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0
51 INT293492 Hsp90aa1 Regulation of Gene_expression of Sfpi1 1 0.04 0.1 0
52 INT287072 Chrm2 Positive_regulation of Gene_expression of Irf4 1 0.18 0.06 0
53 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
54 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
55 INT273949 Binding of Crem and Smarca4 1 0.01 0 0
56 INT291715 Binding of DR1 and Rxra 1 0.09 0 0
57 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
58 INT350715 Sfpi1 Positive_regulation of Transcription of MIR424 1 0.09 0.25 0
59 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
60 INT135175 Myst2 Positive_regulation of Hif1a 1 0.41 0 0
61 INT287060 Proc Regulation of Irf4 1 0.00 0.13 0
62 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
63 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
64 INT287076 Chrm2 Regulation of Irf4 1 0.10 0.09 0
65 INT287068 Irf4 Regulation of Igj 1 0.25 0.13 0
66 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
67 INT236719 Binding of Dr1 and Rxra 1 0.01 0 0
68 INT182939 Binding of DR1 and VDR 1 0.12 0 0
69 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
70 INT203674 Myst2 Positive_regulation of Ros1 1 0.00 1.45 0
71 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
72 INT264407 Binding of DR1 and MMP13 1 0.08 0 0
73 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
74 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
75 INT242879 Positive_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
76 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
77 INT242885 Binding of POU2F1 and SPI1 1 0.01 0 0
78 INT264394 Binding of DR1 and JUN 1 0.01 0.07 0
79 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
80 INT74066 Binding of DR1 and HLA-B 1 0.00 0.08 0
81 INT348035 Map3k7 Positive_regulation of Binding of Chuk 1 0.20 0.06 0
82 INT264401 Binding of DR1 and MMP1 1 0.05 0 0
83 INT26912 SUPT7L Positive_regulation of Localization of Prl 1 0.44 0 0
84 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
85 INT287066 Chrm2 Positive_regulation of Irf4 1 0.18 0.29 0
86 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0
87 INT350705 Sfpi1 Positive_regulation of Mir223 1 0.04 0.13 0
88 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0
89 INT291681 Positive_regulation of Binding of DR1 and RARA 1 0.06 0 0
90 INT225587 Binding of Kat2b and Cytip 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone H3 acetylation. They are ordered first by their pain relevance and then by number of times they were reported in histone H3 acetylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1849 Binding of SUPT7L 14 0.47 0.95 5.44
2 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
3 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
4 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
5 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
6 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
7 INT262317 Binding of TAF9 7 0.31 9.67 2.15
8 INT28412 Gene_expression of SUPT7L 6 0.75 0.79 2.12
9 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04
10 INT102360 Negative_regulation of BRD1 5 0.11 0 1.87
11 INT9702 Localization of SUPT7L 6 0.68 1.11 1.85
12 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
13 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
14 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
15 INT54996 Regulation of KAT2B 1 0.19 0.38 1.45
16 INT43658 Negative_regulation of SUPT7L 3 0.42 0.26 1.35
17 INT102361 Negative_regulation of Negative_regulation of BRD1 1 0.07 0 1.35
18 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
19 INT222843 Positive_regulation of Map3k7 4 0.24 3.04 1.24
20 INT72614 Negative_regulation of Regulation of Tcf3 1 0.41 0.17 1.2
21 INT158278 Positive_regulation of Myst2 2 0.41 0.89 1.02
22 INT59307 Negative_regulation of Binding of SUPT7L 2 0.57 0.51 1.01
23 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1
24 INT173163 Binding of DR1 18 0.16 2.86 0.91
25 INT77167 Positive_regulation of Dr1 2 0.25 0 0.85
26 INT102359 Positive_regulation of BRD1 1 0.08 0 0.85
27 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
28 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
29 INT30050 Gene_expression of Tcf3 13 0.48 2.57 0.77
30 INT77974 Positive_regulation of Gene_expression of SUPT7L 1 0.45 0 0.74
31 INT242889 Binding of SPI1 15 0.36 7.37 0.69
32 INT158279 Regulation of Myst2 2 0.37 0.51 0.65
33 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63
34 INT79936 Positive_regulation of SUPT7L 1 0.49 0 0.63
35 INT105266 Localization of Tcf3 3 0.32 1.08 0.59
36 INT323004 Transcription of TAF9 1 0.05 0.79 0.54
37 INT264419 Negative_regulation of Binding of DR1 1 0.08 1.03 0.45
38 INT200258 Binding of Irf4 2 0.21 0.43 0.43
39 INT248805 Gene_expression of TADA1 1 0.01 0 0.42
40 INT322997 Localization of TAF9 1 0.05 1.2 0.4
41 INT181025 Localization of Sfpi1 3 0.80 4.96 0.38
42 INT102362 Negative_regulation of Positive_regulation of BRD1 1 0.07 0 0.38
43 INT276311 Gene_expression of Irf4 6 0.64 4.95 0.37
44 INT30052 Positive_regulation of Tcf3 3 0.41 0.27 0.37
45 INT287043 Positive_regulation of Irf4 7 0.57 2.81 0.36
46 INT239084 Localization of KAT2B 4 0.73 3.08 0.36
47 INT80141 Negative_regulation of SPI1 6 0.08 5.44 0.34
48 INT84555 Negative_regulation of Spi1 6 0.42 0.71 0.34
49 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
50 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32
51 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31
52 INT266973 Negative_regulation of KAT2B 1 0.01 0.99 0.29
53 INT181051 Transcription of Sfpi1 1 0.62 1.1 0.29
54 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
55 INT222841 Phosphorylation of Map3k7 1 0.16 0.55 0.25
56 INT65739 Gene_expression of Map3k7 1 0.54 1.41 0.25
57 INT297982 Negative_regulation of ING5 1 0.33 1.29 0.24
58 INT242900 Regulation of SPI1 3 0.26 1.12 0.23
59 INT101308 Positive_regulation of Spi1 2 0.67 0.38 0.23
60 INT264459 Gene_expression of DR1 9 0.13 0.95 0.21
61 INT264442 Positive_regulation of DR1 5 0.16 0.42 0.21
62 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21
63 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
64 INT89690 Binding of Brca2 2 0.37 1.8 0.18
65 INT101309 Gene_expression of Spi1 2 0.75 0.64 0.18
66 INT101307 Positive_regulation of Gene_expression of Spi1 1 0.67 0.28 0.18
67 INT106451 Regulation of Spi1 1 0.43 0 0.18
68 INT42672 Transcription of SUPT7L 1 0.67 0 0.17
69 INT212845 Negative_regulation of DR1 2 0.12 0.41 0.15
70 INT90229 Transcription of Tcf3 2 0.12 0.39 0.13
71 INT181033 Regulation of Sfpi1 2 0.40 1.58 0.13
72 INT149543 Binding of TADA1 1 0.37 1.4 0.13
73 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
74 INT103042 Negative_regulation of Myst2 2 0.04 2.09 0.11
75 INT347994 Positive_regulation of Gene_expression of Map3k7 1 0.26 1.27 0.11
76 INT347985 Gene_expression of Map3k7 1 0.35 1.26 0.11
77 INT2228 Protein_catabolism of SUPT7L 1 0.64 0.09 0.1
78 INT32946 Positive_regulation of TADA1 1 0.36 1.31 0.1
79 INT304667 Positive_regulation of SPI1 2 0.13 4.7 0.09
80 INT101082 Positive_regulation of KAT2B 1 0.38 0.76 0.09
81 INT239085 Binding of KAT2B 1 0.18 2.04 0.09
82 INT351182 Positive_regulation of Binding of SPI1 1 0.08 1.25 0.09
83 INT227451 Gene_expression of Myst2 2 0.06 2.98 0.08
84 INT252991 Regulation of TAF9 2 0.44 3.54 0.08
85 INT243209 Positive_regulation of Gene_expression of Myst2 1 0.05 0.93 0.08
86 INT234186 Localization of BRCA2 2 0.69 1.48 0.07
87 INT190543 Localization of Map3k7 1 0.33 0.74 0.07
88 INT264440 Positive_regulation of Binding of DR1 1 0.14 0.21 0.07
89 INT242888 Negative_regulation of Binding of SPI1 1 0.10 0.41 0.06
90 INT242892 Regulation of Binding of SPI1 1 0.08 0.37 0.06
91 INT264453 Positive_regulation of Gene_expression of DR1 6 0.10 0.43 0.05
92 INT273784 Negative_regulation of Gene_expression of DR1 1 0.07 0.43 0.05
93 INT126461 Binding of BRD1 1 0.09 0 0.05
94 INT220802 Binding of LEF1 7 0.36 3.86 0.04
95 INT289116 Positive_regulation of Localization of LEF1 2 0.22 1.19 0.04
96 INT289110 Localization of LEF1 2 0.32 1.19 0.04
97 INT295091 Positive_regulation of Gene_expression of Tcf3 2 0.19 0.4 0.04
98 INT260908 Positive_regulation of Smarca4 2 0.21 0.53 0.03
99 INT264452 Regulation of Gene_expression of DR1 1 0.09 0.2 0.03
100 INT310472 Negative_regulation of Gene_expression of Sfpi1 1 0.41 0.23 0.03
101 INT167536 Positive_regulation of BRCA2 2 0.49 0.29 0
102 INT289127 Positive_regulation of LEF1 2 0.22 0.76 0
103 INT322953 Localization of SPI1 2 0.13 2.17 0
104 INT261756 Gene_expression of Dr1 2 0.26 0.34 0
105 INT234191 Positive_regulation of Localization of BRCA2 1 0.46 0.68 0
106 INT295084 Regulation of Gene_expression of Tcf3 1 0.20 0.36 0
107 INT266482 Phosphorylation of Map3k7 1 0.18 0.26 0
108 INT284294 Transcription of Spi1 1 0.67 0.36 0
109 INT314708 Gene_expression of Brca2 1 0.41 1.75 0
110 INT284295 Negative_regulation of Gene_expression of Spi1 1 0.41 0.36 0
111 INT337456 Positive_regulation of Binding of LEF1 1 0.22 0 0
112 INT314707 Regulation of Transcription of Brca2 1 0.27 0.56 0
113 INT234916 Gene_expression of Lef1 1 0.04 0.25 0
114 INT106452 Negative_regulation of Positive_regulation of Spi1 1 0.30 0 0
115 INT289129 Positive_regulation of Gene_expression of LEF1 1 0.13 0.76 0
116 INT243207 Regulation of Gene_expression of Myst2 1 0.04 0.4 0
117 INT314705 Transcription of Brca2 1 0.42 0.56 0
118 INT291707 Phosphorylation of DR1 1 0.29 0 0
119 INT347996 Binding of Map3k7 1 0.19 0.06 0
120 INT337461 Positive_regulation of Transcription of LEF1 1 0.22 0.26 0
121 INT351181 Positive_regulation of Gene_expression of SPI1 1 0.10 1.87 0
122 INT260913 Negative_regulation of Smarca4 1 0.18 0.29 0
123 INT250466 Regulation of Gene_expression of Sfpi1 1 0.39 0.98 0
124 INT301534 Binding of Dr1 1 0.16 0 0
125 INT173224 Regulation of BRCA2 1 0.21 1.3 0
126 INT273916 Binding of Smarca4 1 0.01 0 0
127 INT293482 Protein_catabolism of Sfpi1 1 0.09 0.52 0
128 INT289108 Negative_regulation of Transcription of LEF1 1 0.11 0.32 0
129 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0
130 INT220775 Binding of Lef1 1 0.20 0.06 0
131 INT271230 Gene_expression of BRD1 1 0.23 0.44 0
132 INT289124 Negative_regulation of Positive_regulation of LEF1 1 0.11 0.34 0
133 INT135168 Binding of Myst2 1 0.28 0 0
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