GO:0044212

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Name transcription regulatory region DNA binding
Categary Function
Go Slim No
Go Link GO:0044212
Unique Molecular Interactions 4228
Total Molecular Interactions 5699
Total Single Events 57643
Pain Genes Associated 189

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transcription regulatory region DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for transcription regulatory region DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
3 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
4 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
5 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
6 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
7 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
8 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
9 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
10 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
11 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
12 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
13 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
14 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
15 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
16 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
17 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
18 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
19 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
20 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
21 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
22 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
23 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
24 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
25 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
26 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
27 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
28 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14
29 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
30 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
31 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
32 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
33 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
34 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
35 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
36 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
37 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
38 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
39 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
40 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
41 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
42 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
43 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
44 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
45 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
46 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
47 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
48 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
49 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
50 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
51 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
52 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
53 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
54 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
55 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
56 INT62065 Binding of YY1 and Penk 3 0.14 0 1.69
57 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
58 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
59 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
60 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
61 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
62 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
63 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
64 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
65 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
66 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
67 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
68 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
69 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
70 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
71 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
72 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
73 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
74 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
75 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
76 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
77 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
78 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
79 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
80 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
81 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41
82 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
83 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
84 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
85 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
86 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
87 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
88 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
89 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
90 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
91 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
92 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
93 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
94 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
95 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
96 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
97 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
98 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
99 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
100 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
101 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
102 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
103 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
104 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
105 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
106 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
107 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
108 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
109 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
110 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
111 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
112 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
113 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 0.12 0.07 1.21
114 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
115 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
116 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
117 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
118 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
119 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
120 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
121 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
122 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
123 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
124 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
125 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
126 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
127 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
128 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
129 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
130 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
131 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
132 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
133 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12
134 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
135 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
136 INT56882 Binding of YY1 and Ppbp 1 0.01 0 1.11
137 INT65254 LOC100360318 Regulation of Gene_expression of Basp1 1 0.00 0.05 1.11
138 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
139 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
140 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
141 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
142 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
143 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
144 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
145 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
146 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
147 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
148 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
149 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
150 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
151 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
152 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
153 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
154 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
155 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
156 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
157 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
158 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
159 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
160 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
161 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
162 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
163 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
164 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
165 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05
166 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
167 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
168 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
169 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
170 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
171 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
172 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
173 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
174 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
175 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
176 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
177 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
178 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
179 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
180 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
181 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
182 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
183 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
184 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
185 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
186 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
187 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
188 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
189 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
190 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
191 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
192 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
193 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
194 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
195 INT59518 YY1 Positive_regulation of SGCG 1 0.50 0.32 0.99
196 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
197 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
198 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
199 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
200 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98

Single Events

The table below shows the top 100 pain related interactions that have been reported for transcription regulatory region DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in transcription regulatory region DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
3 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
4 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
5 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
6 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
7 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
8 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
9 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
10 INT6852 Localization of TNF 883 0.81 705.95 270.84
11 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
12 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
13 INT6481 Binding of TNF 624 0.48 510.2 214.82
14 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
15 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
16 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
17 INT9660 Regulation of TNF 363 0.62 312.94 139.99
18 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
19 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
20 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
21 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
22 INT5587 Regulation of Fos 191 0.62 40.81 99.7
23 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
24 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
25 INT6437 Binding of YY1 154 0.47 26.3 90.46
26 INT10166 Localization of Tnf 237 0.81 153.95 88.64
27 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
28 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
29 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
30 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
31 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
32 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
33 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
34 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
35 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
36 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
37 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
38 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
39 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
40 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
41 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
42 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
43 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
44 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
45 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
46 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
47 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
48 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
49 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
50 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
51 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
52 INT13354 Transcription of TNF 108 0.72 85.81 42.32
53 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
54 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94
55 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
56 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
57 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
58 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33
59 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58
60 INT6053 Transcription of Fos 107 0.72 20.97 31.88
61 INT35406 Localization of Tnf 94 0.81 64.63 31.65
62 INT47764 Binding of Jun 106 0.48 22.62 31.39
63 INT6058 Localization of Fos 73 0.81 16.7 30.84
64 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
65 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
66 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
67 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
68 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8
69 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
70 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
71 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
72 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
73 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35
74 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
75 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
76 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
77 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
78 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
79 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
80 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
81 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
82 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
83 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
84 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
85 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
86 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
87 INT5586 Binding of Fos 47 0.48 12.7 21.33
88 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
89 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
90 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
91 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
92 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
93 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
94 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
95 INT3359 Regulation of YY1 32 0.60 8.19 19.2
96 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
97 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
98 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
99 INT11275 Regulation of Fos 37 0.60 5.79 18.18
100 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
101 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
102 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
103 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
104 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
105 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
106 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
107 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
108 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09
109 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
110 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
111 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
112 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47
113 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
114 INT41558 Localization of Sp1 9 0.48 0.56 14.9
115 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
116 INT93482 Localization of Rela 56 0.78 24.52 14.82
117 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
118 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
119 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
120 INT17593 Regulation of Jun 37 0.60 5.5 14.35
121 INT10173 Binding of Tnf 45 0.48 35.6 14.32
122 INT39733 Localization of NFKB1 59 0.79 22.76 13.99
123 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
124 INT173505 Localization of Hand2 63 0.57 45.32 13.66
125 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64
126 INT71879 Negative_regulation of Localization of Nfkb1 30 0.57 21.8 13.48
127 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
128 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
129 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
130 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
131 INT55168 Binding of NFKB1 55 0.48 22.94 13.15
132 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
133 INT15246 Regulation of FOS 32 0.60 15.34 12.94
134 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
135 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
136 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
137 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
138 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
139 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62
140 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
141 INT70816 Negative_regulation of Fos 32 0.58 13 11.18
142 INT52233 Transcription of Jun 37 0.66 6.39 11.15
143 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
144 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04
145 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
146 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
147 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
148 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
149 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
150 INT60198 Binding of JUN 54 0.48 11.56 10.27
151 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07
152 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02
153 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
154 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
155 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
156 INT18647 Localization of YY1 16 0.78 4.04 9.77
157 INT8527 Positive_regulation of Positive_regulation of Fos 20 0.70 6.87 9.62
158 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49
159 INT71878 Protein_catabolism of Nfkb1 24 0.65 10.85 9.46
160 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
161 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
162 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
163 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
164 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
165 INT67612 Binding of PPARG 38 0.48 22.67 8.94
166 INT35366 Binding of AR 87 0.47 30.52 8.9
167 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
168 INT66213 Localization of RELA 63 0.78 14.71 8.77
169 INT61264 Regulation of Jun 36 0.61 18.42 8.71
170 INT47769 Phosphorylation of Fos 20 0.61 3.03 8.68
171 INT64815 Binding of Jun 49 0.48 21.47 8.59
172 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
173 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
174 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
175 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
176 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23
177 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
178 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89
179 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
180 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
181 INT121977 Phosphorylation of Nfkb1 15 0.51 9.83 7.77
182 INT116552 Positive_regulation of Localization of Nfkb1 16 0.61 12.7 7.74
183 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
184 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
185 INT64816 Transcription of Jun 31 0.69 16.01 7.64
186 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
187 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
188 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
189 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
190 INT68299 Binding of Tnf 17 0.39 12.55 7.49
191 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48
192 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
193 INT10344 Localization of Jun 23 0.73 6.36 7.46
194 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
195 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
196 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
197 INT77404 Gene_expression of ARRB1 19 0.62 1.53 7.22
198 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
199 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
200 INT75497 Regulation of JUN 28 0.61 11.04 7.09
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