GO:0044299

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Name C-fiber
Categary Component
Go Slim No
Go Link GO:0044299
Unique Molecular Interactions 24
Total Molecular Interactions 26
Total Single Events 648
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for C-fiber. They are ordered first by their pain relevance and then by number of times they were reported for C-fiber. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT208621 Binding of Prph and Nmbr 1 0.05 0.43 1.12
2 INT86662 Ngf Regulation of SCN10A 1 0.27 1.24 0.99
3 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
4 INT253165 SCN10A Positive_regulation of OVGP1 1 0.06 1.34 0.61
5 INT98117 Gdnf Regulation of SCN11A 1 0.05 0.39 0.5
6 INT98116 Gdnf Regulation of SCN10A 1 0.03 0.39 0.5
7 INT98119 Gdnf Regulation of SCN10A 1 0.01 0.34 0.45
8 INT98118 Gdnf Regulation of SCN11A 1 0.01 0.34 0.45
9 INT98121 Ngf Regulation of SCN11A 1 0.07 0.29 0.39
10 INT98120 Ngf Regulation of SCN10A 1 0.04 0.29 0.39
11 INT208623 Nmbr Positive_regulation of Prph 1 0.04 0.15 0.36
12 INT156632 Prkaca Regulation of Scn10a 1 0.13 0.67 0.3
13 INT281963 SCN11A Positive_regulation of MDK 1 0.12 0.24 0.26
14 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22
15 INT204477 Binding of App and Scn10a 1 0.17 0.36 0.1
16 INT285381 Scn11a Positive_regulation of Localization of Chst10 1 0.12 0.08 0.06
17 INT204493 App Negative_regulation of Scn10a 1 0.20 0.74 0
18 INT345287 Binding of SCN10A and RAPGEF5 1 0.01 0.67 0
19 INT204480 Fmr1 Negative_regulation of Positive_regulation of Scn10a 1 0.17 0.74 0
20 INT204481 App Negative_regulation of Positive_regulation of Scn10a 1 0.20 0.74 0
21 INT204490 Binding of Fmr1 and Scn10a 1 0.15 0 0
22 INT204486 Fmr1 Negative_regulation of Scn10a 1 0.17 0.74 0
23 INT204496 App Positive_regulation of Scn10a 1 0.20 0.48 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for C-fiber. They are ordered first by their pain relevance and then by number of times they were reported in C-fiber. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT85395 Gene_expression of Scn11a 62 0.78 17.97 26.89
2 INT48248 Gene_expression of Scn10a 38 0.78 19.3 25.05
3 INT78749 Gene_expression of SCN10A 25 0.75 9.23 16.5
4 INT69311 Gene_expression of Scn10a 31 0.78 15.54 14.64
5 INT142941 Negative_regulation of Scn11a 14 0.43 12.2 13.38
6 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24
7 INT85214 Gene_expression of SCN11A 24 0.78 4.05 12.5
8 INT91932 Positive_regulation of Scn10a 18 0.67 10.39 10.9
9 INT83674 Negative_regulation of SCN10A 14 0.59 7.28 9.65
10 INT73323 Negative_regulation of Scn10a 13 0.58 5.77 7.85
11 INT19995 Gene_expression of Prph 16 0.75 8.11 5.52
12 INT124960 Regulation of Scn11a 9 0.52 8.39 5.49
13 INT73322 Transcription of Scn10a 8 0.69 5.35 4.99
14 INT83671 Negative_regulation of SCN11A 6 0.57 2.6 4.91
15 INT8624 Positive_regulation of Scn11a 7 0.46 3.56 4.41
16 INT86647 Localization of SCN10A 8 0.78 3.88 4.27
17 INT97375 Positive_regulation of Gene_expression of Scn10a 5 0.67 2.92 3.98
18 INT46208 Negative_regulation of Scn10a 6 0.58 7.16 3.46
19 INT69313 Regulation of Scn10a 5 0.60 4.45 3.14
20 INT100344 Regulation of Gene_expression of Scn11a 4 0.44 1.6 2.82
21 INT82730 Transcription of Scn10a 3 0.69 2.5 2.53
22 INT236490 Positive_regulation of SCN11A 2 0.48 0.91 2.37
23 INT86483 Localization of SCN11A 4 0.78 1.25 2.23
24 INT73754 Regulation of Gene_expression of Scn10a 3 0.62 1.66 2.15
25 INT36400 Regulation of SCN10A 7 0.62 2.73 1.97
26 INT89714 Regulation of Transcription of Scn10a 3 0.60 2.43 1.9
27 INT8623 Transcription of Scn11a 5 0.58 2.42 1.82
28 INT263066 Negative_regulation of Negative_regulation of Scn11a 1 0.42 2.77 1.78
29 INT73755 Localization of Scn10a 2 0.81 1.82 1.76
30 INT89715 Regulation of Scn10a 3 0.60 1.81 1.61
31 INT83528 Localization of Scn11a 6 0.75 1.51 1.4
32 INT86648 Binding of SCN11A 2 0.36 1.11 1.4
33 INT46206 Positive_regulation of Scn10a 11 0.60 6.57 1.38
34 INT8622 Positive_regulation of Transcription of Scn11a 2 0.45 1.45 1.37
35 INT83606 Negative_regulation of Gene_expression of Scn10a 1 0.43 0.51 1.36
36 INT120521 Negative_regulation of Gene_expression of Scn11a 2 0.42 2.12 1.3
37 INT98795 Negative_regulation of Gene_expression of Scn10a 3 0.57 1.2 1.29
38 INT82728 Positive_regulation of Transcription of Scn10a 1 0.49 1.07 1.25
39 INT85056 Negative_regulation of Transcription of SCN11A 1 0.42 0.96 1.18
40 INT85057 Transcription of SCN11A 1 0.52 0.96 1.17
41 INT84146 Negative_regulation of Negative_regulation of SCN10A 1 0.42 1.11 1.12
42 INT86649 Binding of SCN10A 2 0.36 1.85 1.1
43 INT150630 Positive_regulation of Positive_regulation of Scn10a 1 0.24 0.69 1.04
44 INT152125 Negative_regulation of Gene_expression of Prph 6 0.57 3.28 1.01
45 INT129360 Positive_regulation of Gene_expression of Scn11a 2 0.10 0.49 1.01
46 INT310857 Positive_regulation of Gene_expression of Prph 1 0.14 1.89 0.96
47 INT108622 Binding of Scn10a 2 0.47 0.18 0.9
48 INT83672 Regulation of Negative_regulation of SCN10A 1 0.44 0.37 0.89
49 INT83673 Regulation of Negative_regulation of SCN11A 1 0.44 0.37 0.89
50 INT204461 Localization of Scn10a 4 0.31 2.58 0.79
51 INT49593 Regulation of Prph 2 0.26 0.93 0.73
52 INT355995 Positive_regulation of Prph 1 0.21 1 0.73
53 INT132063 Negative_regulation of Negative_regulation of SCN11A 1 0.15 0 0.73
54 INT318458 Transcription of Prph 1 0.22 0.77 0.72
55 INT220695 Positive_regulation of Gene_expression of Scn10a 2 0.10 2.06 0.7
56 INT142692 Negative_regulation of Transcription of Scn10a 1 0.42 0.74 0.66
57 INT152177 Positive_regulation of Negative_regulation of Scn10a 1 0.43 0.16 0.6
58 INT208612 Binding of Prph 2 0.12 0.54 0.57
59 INT131632 Negative_regulation of Positive_regulation of Scn10a 1 0.41 0.89 0.53
60 INT124043 Regulation of Regulation of Scn10a 1 0.26 0.4 0.48
61 INT69312 Regulation of Gene_expression of Scn10a 1 0.54 0.06 0.43
62 INT156688 Negative_regulation of Negative_regulation of Scn10a 1 0.42 0.07 0.4
63 INT52334 Regulation of SCN11A 1 0.50 0 0.36
64 INT142491 Positive_regulation of Positive_regulation of SCN10A 6 0.61 3.48 0.35
65 INT156631 Regulation of Positive_regulation of Scn10a 1 0.26 0.61 0.34
66 INT320255 Regulation of Regulation of Scn10a 1 0.44 0.19 0.29
67 INT281974 Negative_regulation of Gene_expression of SCN11A 1 0.16 0.46 0.29
68 INT281975 Positive_regulation of Gene_expression of SCN11A 1 0.19 0.47 0.29
69 INT46204 Negative_regulation of Negative_regulation of Scn10a 1 0.37 1.15 0.18
70 INT251741 Regulation of Gene_expression of SCN10A 1 0.45 1.08 0.06
71 INT251742 Regulation of Positive_regulation of SCN10A 1 0.27 1.37 0.06
72 INT208616 Positive_regulation of Binding of Prph 1 0.08 0 0.06
73 INT296812 Negative_regulation of Binding of Scn11a 1 0.02 0.2 0
74 INT296818 Binding of Scn11a 1 0.02 0.14 0
75 INT204464 Binding of Scn10a 1 0.15 1.16 0
76 INT204455 Regulation of Binding of Scn10a 1 0.18 0.72 0
77 INT328234 Negative_regulation of Positive_regulation of SCN10A 1 0.36 0.52 0
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